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收藏Enhancing antibody affinity through experimental sampling of non-deleterious CDR mutations predicted by machine learning
Clark, Thomas; Subramanian, Vidya; Jayaraman, Akila; Fitzpatrick, Emmett; Gopal, Ranjani; Pentakota, Niharika; Rurak, Troy; Anand, Shweta; Viglione, Alexander; Raman, Rahul; Tharakaraman, Kannan; Sasisekharan, Ram
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收藏Generation of bispecific antibodies by structure-guided redesign of IgG constant regions
Iwasaki, Yordkhwan W. W.; Tharakaraman, Kannan; Subramanian, Vidya; Hatas, Andrew; Fleischer, Eduardo; Rurak, Troy T.; Ngok-ngam, Patchara T.; Tit-oon, Phanthakarn; Ruchirawat, Mathuros; Khongmanee, Amnart; Satayavivad, Jutamaad; Fuangthong, Mayuree; Sasisekharan, Ram
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收藏Prediction of the binding interface between monoclonal antibody m102.4 and Nipah attachment glycoprotein using structure-guided alanine scanning and computational docking
Tit-oon, Phanthakarn; Tharakaraman, Kannan; Artpradit, Charlermchai; Godavarthi, Abhinav; Sungkeeree, Pareenart; Sasisekharan, Varun; Kerdwong, Jarunee; Miller, Nathaniel Loren; Mahajan, Bhuvna; Khongmanee, Amnart; Ruchirawat, Mathuros; Sasisekharan, Ram; Fuangthong, Mayuree
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收藏Phase 1 Trial of a Therapeutic Anti-Yellow Fever Virus Human Antibody
Low, Jenny G.; Ng, Justin H. J.; Ong, Eugenia Z.; Kalimuddin, Shirin; Wijaya, Limin; Chan, Yvonne F. Z.; Ng, Dorothy H. L.; Tan, Hwee-Cheng; Baglody, Anjali; Chionh, Yok-Hian; Lee, Debbie C. P.; Budigi, Yadunanda; Sasisekharan, Ram; Ooi, Eng-Eong
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收藏In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
Alekseeva, Anna; Raman, Rahul; Eisele, Giorgio; Clark, Thomas; Fisher, Adam; Lee, Sau (Larry); Jiang, Xiaohui; Torri, Giangiacomo; Sasisekharan, Ram; Bertini, Sabrina
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收藏Structural features of low-molecular-weight heparins affecting their affinity to antithrombin
Bisio, Antonella; Vecchietti, Davide; Citterio, Laura; Guerrini, Marco; Raman, Rahul; Bertini, Sabrina; Eisele, Giorgio; Naggi, Annamaria; Sasisekharan, Ram; Torri, Giangiacomo
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