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L

Lewis C. Cantley

Weill Cornell Medicine
H指数:214
被引数:20.7万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study

极低碳水化合物生酮饮食在初治未接受过治疗的子宫内膜癌伴超重女性中的随机可行性研究

Nature Communications
IF15.7
2026-05-270
OAAI
Ezequiel Dantas; Katie C. Hootman; Jenna Moyer; Morgan Tomberlin; Katherine Curran; Bhavani Ramesh; Hannah Price; Jeshua Kim; Alex C. McPherson; Maurice A. Hurd; Yuan-Shan Zhu; Andrew J. Plodkowski; Erica Nagase; Anastasia Tsomides; Brandon M. Cuevas; M. Laura Martin; John Nguyen; Gabrielle Bennetti; Gissell Botero Rodriguez; Kaity Chang; Marissa Mezzancello; Ginger J. Gardner; Vance Broach; Jennifer J. Mueller; Yukio Sonoda; Oliver Zivanovic; Mario M. Leitao; Alexia Iasonos; Krysten Soldan; Karen Carthew; Vania Hom; Francis N. Villamater; Rema Rao Chaari; Kathryn Gorski; Michael Sigouros; Carol Aghajanian; Olivier Elemento; Lewis C. Cantley; Benjamin D. Hopkins; Britta Weigelt; Lora H. Ellenson; Kari Hacker; Nadeem R. Abu-Rustum; Vicky Makker; Marcus D. Goncalves
Author Correction: Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

作者更正：对致癌基因消除具有抵抗性的胰腺癌细胞依赖于线粒体功能

Nature
IF48.5
2026-04-080
PRE
Andrea Viale; Piergiorgio Pettazzoni; Costas A. Lyssiotis; Haoqiang Ying; Nora Sánchez; Matteo Marchesini; Alessandro Carugo; Tessa Green; Sahil Seth; Virginia Giuliani; Maria Kost-Alimova; Florian Muller; Simona Colla; Luigi Nezi; Giannicola Genovese; Angela K. Deem; Avnish Kapoor; Wantong Yao; Emanuela Brunetto; Ya’an Kang; Min Yuan; John M. Asara; Y. Alan Wang; Timothy P. Heffernan; Alec C. Kimmelman; Huamin Wang; Jason B. Fleming; Lewis C. Cantley; Ronald A. DePinho; Giulio F. Draetta
Publisher Correction: Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity

出版者更正：基于基序的胞质受体样激酶BIK1底物作图揭示了植物免疫的新型组分和调控节点

Nature Plants
IF13.6
2026-03-030
OA
Ryan Toth; Sera Choi; Marie Le Naour--Vernet; Florian Schwanke; Jared L. Johnson; Estee E. Tee; Tomer M. Yaron-Barir; Eleanor Khochaba; Paul Derbyshire; Anka Colo; Philipp Köster; Emily M. Huntsman; Laura Herold; Yoonyoung Lee; Álvaro D. Fernández-Fernández; Hee-Kyung Ahn; Julian Dindas; Marta Bjornson; Jack Rhodes; Beibei Song; Weibing Wang; Marija Smokvarska; Emmanuelle M. Bayer; Jian-Min Zhou; Lewis C. Cantley; Jonathan D. G. Jones; Kyle W. Bender; Frank L. H. Menke; Christine Faulkner; Cyril Zipfel; Thomas A. DeFalco
Comprehensive evaluation of phosphoproteomic-based kinase activity inference

基于磷酸蛋白质组学的激酶活性推断的综合评价

Nature Communications
IF15.7
2025-05-220
OAAI
Sophia Müller-Dott; Eric J. Jaehnig; Khoi Pham Munchic; Wen Jiang; Tomer M. Yaron-Barir; Sara R. Savage; Martin Garrido-Rodriguez; Jared L. Johnson; Alessandro Lussana; Evangelia Petsalaki; Jonathan T. Lei; Aurelien Dugourd; Karsten Krug; Lewis C. Cantley; D. R. Mani; Bing Zhang; Julio Saez-Rodriguez
Multi-node inhibition targeting mTORC1, mTORC2 and PI3Kα potently inhibits the PI3K/AKT/mTOR pathway in endometrial and breast cancer models

Tyrakis, P.A.等人（2025）多节点抑制靶向mTORC1、mTORC2和PI3Kα，在子宫内膜癌和乳腺癌模型中强效抑制PI3K/AKT/mTOR通路。Br. J. Cancer, 133, 144–154。

British Journal of Cancer
IF6.8
2025-05-130
OAAI
Petros A. Tyrakis; Domen Kampjut; Georgina F. Steele; H. Jonathan G. Lindström; Deborah Chirnomas; Benjamin D. Hopkins; Marcus D. Goncalves; Siddhartha Mukherjee; Lewis C. Cantley; Oliver D. K. Maddocks
Phosphoproteomics-directed manipulation reveals SEC22B as a hepatocellular signaling node governing metabolic actions of glucagon

磷酸化蛋白质组学指导的操作揭示了SEC22B作为控制胰高血糖素代谢作用的肝细胞信号节点

NATURE COMMUNICATIONS
IF15.7
2024-09-271
OAAI
Wu, Yuqin; Foollee, Ashish; Chan, Andrea Y.; Hille, Susanne; Hauke, Jana; Challis, Matthew P.; Johnson, Jared L.; Yaron, Tomer M.; Mynard, Victoria; Aung, Okka H.; Cleofe, Maria Almira S.; Huang, Cheng; Lim Kam Sian, Terry C. C.; Rahbari, Mohammad; Gallage, Suchira; Heikenwalder, Mathias; Cantley, Lewis C.; Schittenhelm, Ralf B.; Formosa, Luke E.; Smith, Greg C.; Okun, Juergen G.; Mueller, Oliver J.; Rusu, Patricia M.; Rose, Adam J.
Paediatric strategy forum for medicinal product development of PI3-K, mTOR, AKT and GSK3β inhibitors in children and adolescents with cancer

儿童和青少年癌症PI3-K、mTOR、AKT和GSK3β 抑制剂药物开发儿科战略论坛

EUROPEAN JOURNAL OF CANCER
IF7.1
2024-08-010
PRE
Pearson, Andrew D. J.; DuBois, Steven G.; Macy, Margaret E.; de Rojas, Teresa; Donoghue, Martha; Weiner, Susan; Knoderer, Holly; Bernardi, Ronald; Buenger, Vickie; Canaud, Guillaume; Cantley, Lewis; Chung, John; Fox, Elizabeth; Friend, John; Glade-Bender, Julia; Gorbatchevsky, Igor; Gore, Lia; Gupta, Abha; Hawkins, Douglas S.; Juric, Dejan; Lang, Leigh Anna; Leach, Danielle; Liaw, Danny; Lesa, Giovanni; Ligas, Franca; Lindberg, Gavin; Lindberg, Wendy; Ludwinski, Donna; Marshall, Lynley; Mazar, Andrew; McDonough, Joe; Nysom, Karsten; Urs, Christopher O.; Pappo, Alberto; Parsons, D. William; Rosenfeld, Amy; Scobie, Nicole; Smith, Malcolm; Taylor, Danielle; Weigel, Brenda; Weinstein, Amy; Karres, Dominik; Vassal, Gilles
Genome- wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase

球体培养中的全基因组CRISPR筛选揭示了肿瘤抑制因子LKB1通过PIKFYVE脂质激酶抑制生长

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-05-141
OAAI
Ferrarone, John R.; Thomas, Jerin; Unni, Arun M.; Zheng, Yuxiang; Nagiec, Michal J.; Gardner, Eric E.; Mashadova, Oksana; Li, Kate; Koundouros, Nikos; Montalbano, Antonino; Mustafa, Meer; Cantley, Lewis C.; Blenis, John; Sanjana, Neville E.; Varmus, Harold
The intrinsic substrate specificity of the human tyrosine kinome
Nature
IF48.5
2024-05-080
OAAI
Tomer M. Yaron-Barir; Brian A. Joughin; Emily M. Huntsman; Alexander Kerelsky; Daniel M. Cizin; Benjamin M. Cohen; Amit Regev; Junho Song; Neil Vasan; Ting-Yu Lin; Jose M. Orozco; Christina Schoenherr; Cari Sagum; Mark T. Bedford; R. Max Wynn; Shih-Chia Tso; David T. Chuang; Lei Li; Shawn S.-C. Li; Pau Creixell; Konstantin Krismer; Mina Takegami; Harin Lee; Bin Zhang; Jingyi Lu; Ian Cossentino; Sean D. Landry; Mohamed Uduman; John Blenis; Olivier Elemento; Margaret C. Frame; Peter V. Hornbeck; Lewis C. Cantley; Benjamin E. Turk; Michael B. Yaffe; Jared L. Johnson

研究方向

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J
John M. Asara
H 指数:115论文数:839被引数:6.0万
J
Jared L. Johnson
H 指数:32论文数:111被引数:4,849
T
Tomer M. Yaron
H 指数:25论文数:82被引数:3,132
C
Costas A. Lyssiotis
H 指数:79论文数:765被引数:3.2万
M
Matthew G. Vander Heiden
H 指数:119论文数:700被引数:9.0万
J
Ji Luo
H 指数:48论文数:157被引数:2.1万
O
Olivier Elemento
H 指数:117论文数:1,686被引数:6.3万
G
Gerburg M. Wulf
H 指数:52论文数:366被引数:1.2万
J
John Blenis
H 指数:112论文数:334被引数:6.7万
J
Jason W. Locasale
H 指数:91论文数:434被引数:4.2万