Elizabeth A. Blackburn - Publications, H-index & Citations

Elizabeth A. Blackburn

University of Edinburgh

19H指数

43论文数

1.0K被引数

收录论文 25

发表时间

A lymphostatin homologue from Chlamydia pecorum inhibits mitogen-activated bovine T cell proliferation and IFNγ production Chlamydia pecorum来源的淋巴稳定素同系物抑制丝裂原激活的牛T细胞增殖和IFNγ产生

VIRULENCE

IF5.4

2025-05-22

OAAI

Elizabeth A. Blackburn; Cosmin Chintoan-Uta; Andrew G. Bease; Maarten W. Tuijtel; Max Hateley; Martin Wear; David Longbottom; Robin Cassady-Cain; Mark P. Stevens

Chemically cross-linked hydrogels from repetitive protein arrays

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2023-09-01

OAAI

Boni, Rossana; Blackburn, Elizabeth. A.; Kleinjan, Dirk-Jan; Jonaitis, Mantas; Hewitt-Harris, Flora; Murdoch, Megan; Rosser, Susan; Hay, David. C.; Regan, Lynne

Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC

JOURNAL OF CELL BIOLOGY

IF6.4

2022-07-01

OAAI

Abad, Maria Alba; Gupta, Tanmay; Hadders, Michael A.; Meppelink, Amanda; Wopken, J. Pepijn; Blackburn, Elizabeth; Zou, Juan; Gireesh, Anjitha; Buzuk, Lana; Kelly, David A.; McHugh, Toni; Rappsilber, Juri; Lens, Susanne M. A.; Jeyaprakash, A. Arockia

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice 速效变构磷酸果糖激酶抑制剂阻断锥虫糖酵解并治愈小鼠急性非洲锥虫病

NATURE COMMUNICATIONS

IF15.7

2021-02-16

OAAI

McNae, Iain W.; Kinkead, James; Malik, Divya; Yen, Li-Hsuan; Walker, Martin K.; Swain, Chris; Webster, Scott P.; Gray, Nick; Fernandes, Peter M.; Myburgh, Elmarie; Blackburn, Elizabeth A.; Ritchie, Ryan; Austin, Carol; Wear, Martin A.; Highton, Adrian J.; Keats, Andrew J.; Vong, Antonio; Dornan, Jacqueline; Mottram, Jeremy C.; Michels, Paul A. M.; Pettit, Simon; Walkinshaw, Malcolm D.

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment

JOURNAL OF CELL SCIENCE

IF3.6

2020-08-25

OAAI

Legal, Thibault; Hayward, Daniel; Gluszek-Kustusz, Agata; Blackburn, Elizabeth A.; Spanos, Christos; Rappsilber, Juri; Gruneberg, Ulrike; Welburn, Julie P. I.

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

CHEMICAL SCIENCE

IF7.4

2019-01-01

OAAI

De Simone, Alessio; Georgiou, Charis; Ioannidis, Harris; Gupta, Arun A.; Juarez-Jimenez, Jordi; Doughty-Shenton, Dahlia; Blackburn, Elizabeth A.; Wear, Martin A.; Richards, Jonathan P.; Barlow, Paul N.; Carragher, Neil; Walkinshaw, Malcolm D.; Hulme, Alison N.; Michel, Julien

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation 半胱氨酸氧化和S-亚硝化对丙酮酸激酶M2的氧化还原调节

BIOCHEMICAL JOURNAL

IF4.3

2018-10-31

OAAI

Mitchell, Alice Rose; Yuan, Meng; Morgan, Hugh P.; McNae, Iain W.; Blackburn, Elizabeth A.; Le Bihan, Thierry; Homem, Rafael A.; Yu, Manda; Loake, Gary J.; Michels, Paul A.; Wear, Martin A.; Walkinshaw, Malcolm D.

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor M2丙酮酸激酶作为氨基酸传感器的同种异体机制

BIOCHEMICAL JOURNAL

IF4.3

2018-05-31

OAAI

Yuan, Meng; McNae, Iain W.; Chen, Yiyuan; Blackburn, Elizabeth A.; Wear, Martin A.; Michels, Paul A. M.; Fothergill-Gilmore, Linda A.; Hupp, Ted; Walkinshaw, Malcolm D.

Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2018-04-09

OAAI

Gur, Mert; Blackburn, Elizabeth A.; Ning, Jia; Narayan, Vikram; Ball, Kathryn L.; Walkinshaw, Malcolm D.; Erman, Burak

Novel Entropically Driven Conformation-specific Interactions with Tomm34 Protein Modulate Hsp70 Protein Folding and ATPase Activities

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2016-05-01

OAAI

Durech, Michal; Trcka, Filip; Man, Petr; Blackburn, Elizabeth A.; Hernychova, Lenka; Dvorakova, Petra; Coufalova, Dominika; Kavan, Daniel; Vojtesek, Borivoj; Muller, Petr

Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-03-01

OAAI

Cassady-Cain, Robin L.; Blackburn, Elizabeth A.; Alsarraf, Husam; Dedic, Emil; Bease, Andrew G.; Boettcher, Bettina; Jorgensen, Rene; Wear, Martin; Stevens, Mark P.

Protein-Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2015-11-01

OAAI

Narayan, Vikram; Landre, Vivien; Ning, Jia; Hernychova, Lenka; Muller, Petr; Verma, Chandra; Walkinshaw, Malcolm D.; Blackburn, Elizabeth A.; Ball, Kathryn L.

Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90

BIOSCIENCE REPORTS

IF4.7

2015-10-19

OAAI

Blackburn, Elizabeth A.; Wear, Martin A.; Landre, Vivian; Narayan, Vikram; Ning, Jia; Erman, Burak; Ball, Kathryn L.; Walkinshaw, Malcolm D.

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA plus superfamily oncoprotein reptin 发现调节AAA加超家族癌蛋白reptin的蛋白质-蛋白质相互作用的新型配体

CHEMICAL SCIENCE

IF7.4

2015-01-01

OAAI

Healy, Alan R.; Houston, Douglas R.; Remnant, Lucy; Huart, Anne-Sophie; Brychtova, Veronika; Maslon, Magda M.; Meers, Olivia; Muller, Petr; Krejci, Adam; Blackburn, Elizabeth A.; Vojtesek, Borek; Hernychova, Lenka; Walkinshaw, Malcolm D.; Westwood, Nicholas J.; Hupp, Ted R.

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2014-12-15

183

OAAI

Guenther, Claudia; Kind, Barbara; Reijns, Martin A. M.; Berndt, Nicole; Martinez-Bueno, Manuel; Wolf, Christine; Tuengler, Victoria; Chara, Osvaldo; Lee, Young Ae; Huebner, Norbert; Bicknell, Louise; Blum, Sophia; Krug, Claudia; Schmidt, Franziska; Kretschmer, Stefanie; Koss, Sarah; Astell, Katy R.; Ramantani, Georgia; Bauerfeind, Anja; Morris, David L.; Graham, Deborah S. Cunninghame; Bubeck, Doryen; Leitch, Andrea; Ralston, Stuart H.; Blackburn, Elizabeth A.; Gahr, Manfred; Witte, Torsten; Vyse, Timothy J.; Melchers, Inga; Mangold, Elisabeth; Noethen, Markus M.; Aringer, Martin; Kuhn, Annegret; Luethke, Kirsten; Unger, Leonore; Bley, Annette; Lorenzi, Alice; Isaacs, John D.; Alexopoulou, Dimitra; Conrad, Karsten; Dahl, Andreas; Roers, Axel; Alarcon-Riquelme, Marta E.; Jackson, Andrew P.; Lee-Kirsch, Min Ae

An X-ray crystal structure-based understanding of the inhibition of the MDM2-p53 protein-protein interaction by isoindolinones

EUROPEAN JOURNAL OF CANCER

IF7.1

2014-11-01

PREAI

Anil, B.; Blackburn, E.; Blackburn, T.; Cully, S.; Liu, J.; Drummond, C. J.; Endicott, J. A.; Golding, B. T.; Griffin, R. J.; Haggerty, K.; Lunec, J.; Newell, D. R.; Revill, C. H.; Riedinger, C.; Watson, A. F.; Xu, Q.; Zhao, Y.; Hardcastle, I. R.; Noble, M. E. M.

A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2

CELLULAR SIGNALLING

IF3.7

2014-06-01

PREAI

Nicholson, Judith; Scherl, Alex; Way, Luke; Blackburn, Elizabeth A.; Walkinshaw, Malcolm D.; Ball, Kathryn L.; Hupp, Ted R.

Q&A: Elizabeth Blackburn on Telomerase and Tumors

CANCER DISCOVERY

IF33.3

2013-12-10

PREAI

Bender, Eric; Blackburn, Elizabeth

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase

BIOCHEMICAL JOURNAL

IF4.3

2012-10-18

OAAI

Morgan, Hugh P.; Walsh, Martin J.; Blackburn, Elizabeth A.; Wear, Martin A.; Boxer, Matthew B.; Shen, Min; Veith, Henrike; McNae, Iain W.; Nowicki, Matthew W.; Michels, Paul A. M.; Auld, Douglas S.; Fothergill-Gilmore, Linda A.; Walkinshaw, Malcolm D.

The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-09-01

OAAI

Soares, Dinesh C.; Bradshaw, Nicholas J.; Zou, Juan; Kennaway, Christopher K.; Hamilton, Russell S.; Chen, Zhuo A.; Wear, Martin A.; Blackburn, Elizabeth A.; Bramham, Janice; Boettcher, Bettina; Millar, J. Kirsty; Barlow, Paul N.; Walkinshaw, Malcolm D.; Rappsilber, Juri; Porteous, David J.

研究方向