Paul J. Hergenrother - Publications, H-index & Citations

Paul J. Hergenrother

University of Illinois at Urbana Champaign

58H指数

449论文数

1.4W被引数

收录论文 153

发表时间

FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer FGD3介导裂解性细胞死亡，增强化疗药物在乳腺癌中的疗效和免疫原性。

Journal of Experimental & Clinical Cancer Research

IF12.8

2025-11-18

OAAI

Junyao Zhu; Xinyi Dai; Santanu Ghosh; Elaine Wei; Chengjian Mao; Qianjin Jiang; Abigail J. Spaulding; Michael P. Mulligan; Roger Romero; Yoo Jane Han; Matthew W. Boudreau; Olufunmilayo Olopade; Paul J. Hergenrother; David J. Shapiro

A necrosis inducer promotes an immunogenic response and destroys ovarian cancers in mouse xenografts and patient ascites organoids 坏死诱导剂促进免疫原性反应并破坏小鼠异种移植瘤和患者腹水类器官中的卵巢癌

CANCER LETTERS

IF10.1

2025-06-04

PREAI

Duraki, Darjan; Jabeen, Musarrat; Mao, Chengjian; Wang, Lawrence; Ghosh, Santanu; Dai, Xinyi; Zhu, Junyao; Boudreau, Matthew W.; Nelson, Erik R.; Hergenrother, Paul J.; Cheng, Georgina; Shapiro, David J.

PAC-1 Synergizes with Sunitinib to Enhance Cell Death in Pancreatic Neuroendocrine Tumors PAC-1与舒尼替尼协同作用以增强胰腺神经内分泌肿瘤的细胞死亡

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-04-02

PREAI

Lee, HY; Lee, MR; Fan, TM; Hergenrother, PJ

Single Dose of a Small Molecule Leads to Complete Regressions of Large Breast Tumors in Mice 单次给予小分子剂量可导致小鼠大型乳腺癌肿瘤完全消退。

ACS CENTRAL SCIENCE

IF10.4

2025-01-22

OAAI

Mulligan, MP; Boudreau, MW; Bouwens, BA; Lee, Y; Carrell, HW; Zhu, JY; Mousses, S; Shapiro, DJ; Nelson, ER; Fan, TM; Hergenrother, PJ

Simultaneous Targeting of NQO1 and SOD1 Eradicates Breast Cancer Stem Cells via Mitochondrial Futile Redox Cycling

CANCER RESEARCH

IF16.6

2024-09-12

OAAI

Luo, Ming; Shen, Na; Shang, Li; Fang, Zeng; Xin, Ying; Ma, Yuxi; Du, Min; Yuan, Yuan; Hu, Chenchen; Tang, Yun; Huang, Jing; Wei, Wei; Lee, Myung Ryul; Hergenrother, Paul J.; Wicha, Max S.

Raptinal: a powerful tool for rapid induction of apoptotic cell death

CELL DEATH DISCOVERY

IF7

2024-08-21

OAAI

Smith, Amanda J.; Hergenrother, Paul J.

Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells

CANCER LETTERS

IF10.1

2024-08-01

OAAI

Gamage, Hashni Epa Vidana; Albright, Samuel T.; Smith, Amanda J.; Farmer, Rachel; Shahoei, Sayyed Hamed; Wang, Yu; Fink, Emma C.; Jacquin, Elise; Weisser, Erin; Bautista, Rafael O.; Henn, Madeline A.; Schane, Claire P.; Nelczyk, Adam T.; Ma, Liqian; Das Gupta, Anasuya; Bendre, Shruti V.; Nguyen, Tiffany; Tiwari, Srishti; Krawczynska, Natalia; He, Sisi; Tjoanda, Evelyn; Chen, Hong; Sverdlov, Maria; Gann, Peter H.; Boidot, Romain; Vegran, Frederique; Fanning, Sean W.; Apetoh, Lionel; Hergenrother, Paul J.; Nelson, Erik R.

NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors

CANCER LETTERS

IF10.1

2024-08-01

OAAI

Gamage, Hashni Epa Vidana; Shahoei, Sayyed Hamed; Wang, Yu; Jacquin, Elise; Weisser, Erin; Bautista, Rafael O.; Henn, Madeline A.; Schane, Claire P.; Nelczyk, Adam T.; Ma, Liqian; Das Gupta, Anasuya; Bendre, Shruti, V; Nguyen, Tiffany; Tiwari, Srishti; Tjoanda, Evelyn; Krawczynska, Natalia; He, Sisi; Albright, Samuel T.; Farmer, Rachel; Smith, Amanda J.; Fink, Emma C.; Chen, Hong; Sverdlov, Maria; Gann, Peter H.; Boidot, Romain; Vegran, Frederique; Fanning, Sean W.; Hergenrother, Paul J.; Apetoh, Lionel; Nelson, Erik R.

Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging

JOURNAL OF BIOMEDICAL OPTICS

IF2.9

2024-07-16

OAAI

Hur, Sun Woong; Kwon, Minsung; Manoharaan, Revathi; Mohammadi, Melika Haji; Samuel, Ashok Zachariah; Mulligan, Michael P.; Hergenrother, Paul J.; Bhargava, Rohit

Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1-Positive Pancreatic Cancer Cells

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2024-07-01

PREAI

Jiang, Lingxiang; Liu, Yingchun; Tumbath, Soumya; Boudreau, Matthew W.; Chatkewitz, Lindsay E.; Wang, Jiangwei; Su, Xiaolin; Zahid, Kashif Rafiq; Li, Katherine; Chen, Yaomin; Yang, Kai; Hergenrother, Paul J.; Huang, Xiumei

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

SCIENTIFIC REPORTS

IF3.9

2024-06-20

OAAI

Gonzalez-Lopez, Adrian; Larsson, Daniel S. D.; Koripella, Ravi Kiran; Cain, Brett N.; Chavez, Martin Garcia; Hergenrother, Paul J.; Sanyal, Suparna; Selmer, Maria

Small molecule procaspase activating compound 1 (PAC-1) enhances CAR-T immunotherapy for solid tumors in syngeneic murine models

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Ranoa, Diana R.; Kang, Yifei; Drnevich, Jenny; Rendon, Gloria; Fields, Christopher J.; Bailey, Keith; Roy, Edward J.; Fan, Timothy M.; Kranz, David M.; Hergenrother, Paul J.

A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain (vol 18, pg 1200, 2023)

ACS CHEMICAL BIOLOGY

IF3.8

2024-03-27

OAAI

Anmangandla, Ananya; Jana, Sadhan; Peng, Kewen; Wallace, Shamar D.; Bagde, Saket R.; Drown, Bryon S.; Xu, Jiashu; Hergenrother, Paul J.; Fromme, J. Christopher; Lin, Hening

A novel pathway controlling anticancer drug induced immunogenic cell death

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Zhu, Junyao; Ghosh, Santanu; Duraki, Darjan; Boudreau, Matthew; Jabeen, Musarrat; Mao, Chengjian; Park, Ben H.; Cheng, Georgina; Nelson, Erik R.; Hergenrother, Paul J.; Shapiro, David J.

Precise Readout of MEK1 Proteoforms upon MAPK Pathway Modulation by Individual Ion Mass Spectrometry

ANALYTICAL CHEMISTRY

IF6.7

2024-03-08

PREAI

Drown, Bryon S.; Gupta, Raveena; Mcgee, John P.; Hollas, Michael A. R.; Hergenrother, Paul J.; Kafader, Jared O.; Kelleher, Neil L.

Using permeation guidelines to design new antibiotics-A PASsagE into Pseudomonas aeruginosa

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2024-03-01

OAAI

Cain, Brett N.; Hergenrother, Paul J.

A catalytic process enables efficient and programmable access to precisely altered indole alkaloid scaffolds

NATURE CHEMISTRY

IF20.2

2024-02-19

PREAI

Huang, Youming; Li, Xinghan; Mai, Binh Khanh; Tonogai, Emily J.; Smith, Amanda J.; Hergenrother, Paul J.; Liu, Peng; Hoveyda, Amir H.

Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-Induced Necrosis

CANCER RESEARCH

IF16.6

2023-07-31

OAAI

Ghosh, Santanu; Yang, Rachel; Duraki, Darjan; Zhu, Junyao; Kim, Ji Eun; Jabeen, Musarrat; Mao, Chengjian; Dai, Xinyi; Livezey, Mara R.; Boudreau, Matthew W.; Park, Ben H.; Nelson, Erik R.; Hergenrother, Paul J.; Shapiro, David J.

Phase I dose-escalation study of procaspase-activating compound-1 in combination with temozolomide in patients with recurrent high-grade astrocytomas

NEURO-ONCOLOGY ADVANCES

IF4.1

2023-07-19

OAAI

Holdhoff, Matthias; Nicholas, M. Kelly; Peterson, Richard A.; Maraka, Stefania; Liu, Li C.; Fischer, James H.; Wefel, Jeffrey S.; Fan, Timothy M.; Vannorsdall, Tracy; Russell, Meredith; Iacoboni, Michaella; Tarasow, Theodore M.; Hergenrother, Paul J.; Dudek, Arkadiusz Z.; Danciu, Oana C.

Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2023-05-31

OAAI

Ranoa, Diana Rose E.; Sharma, Preeti; Schane, Claire P.; Lewis, Amber N.; Valdez, Edward; Marada, Venkata V. V. R.; Hager, Marlies, V; Montgomery, Will; Wolf, Steven P.; Schreiber, Karin; Schreiber, Hans; Bailey, Keith; Fan, Timothy M.; Hergenrother, Paul J.; Roy, Edward J.; Kranz, David M.

研究方向