未登录 A proposed screening strategy for evaluating the genotoxicity potential of botanicals and botanical extracts Witt, Kristine L.; van Benthem, Jan; Kobets, Tetyana; Chen, Guosheng; Kelber, Olaf; Krzykwa, Julie; Macgregor, James T.; Mei, Nan; Mitchell, Constance A.; Rietjens, Ivonne; Sarigol-Kilic, Zehra; Smith-Roe, Stephanie L.; Stopper, Helga; Thakkar, Yax; Zeiger, Errol; Pfuhler, Stefan 分享 收藏
Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R Yang, Shu; Zhang, Li; Khan, Kamal; Travers, Jameson; Huang, Ruili; Jovanovic, Vukasin M.; Veeramachaneni, Rithvik; Sakamuru, Srilatha; Tristan, Carlos A.; Davis, Erica E.; Klumpp-Thomas, Carleen; Witt, Kristine L.; Simeonov, Anton; Shaw, Natalie D.; Xia, Menghang 分享 收藏
Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing Marchetti, Francesco; Cardoso, Renato; Chen, Connie L. L.; Douglas, George R.; Elloway, Joanne; Escobar, Patricia A.; Harper Jr, Tod; Heflich, Robert H.; Kidd, Darren; Lynch, Anthony M.; Myers, Meagan B.; Parsons, Barbara L.; Salk, Jesse J.; Settivari, Raja S.; Smith-Roe, Stephanie L.; Witt, Kristine L.; Yauk, Carole; Young, Robert R.; Zhang, Shaofei; Minocherhomji, Sheroy 分享 收藏
Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation Ooka, Masato; Zhao, Jinghua; Shah, Pranav; Travers, Jameson; Klumpp-Thomas, Carleen; Xu, Xin; Huang, Ruili; Ferguson, Stephen; Witt, Kristine L.; Smith-Roe, Stephanie L.; Simeonov, Anton; Xia, Menghang 分享 收藏
Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells Seo, Ji-Eun; Guo, Xiaoqing; Petibone, Dayton M.; Shelton, Sharon D.; Chen, Ying; Li, Xilin; Tryndyak, Volodymyr; Smith-Roe, Stephanie L.; Witt, Kristine L.; Mei, Nan; Manjanatha, Mugimane G. 分享 收藏
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Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines 使用具有代谢能力的TK6细胞系评估吡咯里西啶生物碱诱导的遗传毒性 Li, Xilin; He, Xiaobo; Chen, Si; Guo, Xiaoqing; Bryant, Matthew S.; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan 分享 收藏
Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing (vol 175, pg 251, 2020) Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan 分享 收藏
Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies Frawley, Rachel P.; Witt, Kristine L.; Cunny, Helen; Germolec, Dori R.; Jackson-Humbles, Daven; Malarkey, David; Shockley, Keith R.; Stout, Matthew; Travlos, Greg; Buccellato, Matthew; Fallacara, Dawn; Harris, Shawn; Kissling, Grace E.; Manheng, Wimolnut; Surh, Irene Inok; White, Kimber, Jr.; Auerbach, Scott S. 分享 收藏
Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing 表达人细胞色素P450s TK6-derived细胞的研制及其在遗传毒性检测中的应用 Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G.; Zhou, Tong; Witt, Kristine L.; Mei, Nan 分享 收藏
Genetic toxicology in silico protocol 计算机协议中的遗传毒理学 Hasselgren, Catrin; Ahlberg, Ernst; Akahori, Yumi; Amberg, Alexander; Anger, Lennart T.; Atienzar, Franck; Auerbach, Scott; Beilke, Lisa; Bellion, Phillip; Benigni, Romualdo; Bercu, Joel; Booth, Ewan D.; Bower, Dave; Brigo, Alessandro; Cammerer, Zoryana; Cronin, Mark T. D.; Crooks, Ian; Cross, Kevin P.; Custer, Laura; Dobo, Krista; Doktorova, Tatyana; Faulkner, David; Ford, Kevin A.; Fortin, Marie C.; Frericks, Markus; Gad-McDonald, Samantha E.; Gellatly, Nichola; Gerets, Helga; Gervais, Veronique; Glowienke, Susanne; Van Gompel, Jacky; Harvey, James S.; Hillegass, Jedd; Honma, Masamitsu; Hsieh, Jui-Hua; Hsu, Chia-Wen; Barton-Maclaren, Tara S.; Johnson, Candice; Jolly, Robert; Jones, David; Kemper, Ray; Kenyon, Michelle O.; Kruhlak, Naomi L.; Kulkarni, Sunil A.; Kuemmerer, Klaus; Leavitt, Penny; Masten, Scott; Miller, Scott; Moudgal, Chandrika; Muster, Wolfgang; Paulino, Alexandre; Lo Piparo, Elena; Powley, Mark; Quigley, Donald P.; Reddy, M. Vijayaray; Richarz, Andrea-Nicole; Schilter, Benoit; Snyder, Ronald D.; Stavitskaya, Lidiya; Stidl, Reinhard; Szabo, David T.; Teasdale, Andrew; Tice, Raymond R.; Trejo-Martin, Alejandra; Vuorinen, Anna; Wall, Brian A.; Watts, Pete; White, Angela T.; Wichard, Joerg; Witt, Kristine L.; Woolley, Adam; Woolley, David; Zwickl, Craig; Myatt, Glenn J. 分享 收藏
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Identifying Compounds with Genotoxicity Potential Using Tox21 High-Throughput Screening Assays Hsieh, Jui-Hua; Smith-Roe, Stephanie L.; Huang, Ruili; Sedykh, Alexander; Shockley, Keith R.; Auerbach, Scott S.; Merrick, B. Alex; Xia, Menghang; Tice, Raymond R.; Witt, Kristine L. 分享 收藏
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How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract Catlin, Natasha R.; Collins, Bradley J.; Auerbach, Scott S.; Ferguson, Stephen S.; Harnly, James M.; Gennings, Chris; Waidyanatha, Suramya; Rice, Glenn E.; Smith-Roe, Stephanie L.; Witt, Kristine L.; Rider, Cynthia V. 分享 收藏
Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 通过深入的机理研究对影响线粒体功能的Tox21 10k化学物质进行综合分析和优先排序 Xia, Menghang; Huang, Ruili; Shi, Qiang; Boyd, Windy A.; Zhao, Jinghua; Sun, Nuo; Rice, Julie R.; Dunlap, Paul E.; Hackstadt, Amber J.; Bridge, Matt F.; Smith, Marjolein V.; Dai, Sheng; Zheng, Wei; Chu, Pei-Hsuan; Gerhold, David; Witt, Kristine L.; DeVito, Michael; Freedman, Jonathan H.; Austin, Christopher P.; Houck, Keith A.; Thomas, Russell S.; Paules, Richard S.; Tice, Raymond R.; Simeonov, Anton 分享 收藏
In silico toxicology protocols 计算机毒理学协议 Myatt, Glenn J.; Ahlberg, Ernst; Akahori, Yumi; Allen, David; Amberg, Alexander; Anger, Lennart T.; Aptula, Aynur; Auerbach, Scott; Beilke, Lisa; Bellion, Phillip; Benigni, Romualdo; Bercu, Joel; Booth, Ewan D.; Bower, Dave; Brigo, Alessandro; Burden, Natalie; Cammerer, Zoryana; Cronin, Mark T. D.; Cross, Kevin P.; Custer, Laura; Dettwiler, Magdalena; Dobo, Krista; Ford, Kevin A.; Fortin, Marie C.; Gad-McDonald, Samantha E.; Gellatly, Nichola; Gervais, Veronique; Glover, Kyle P.; Glowienke, Susanne; Van Gompel, Jacky; Gutsell, Steve; Hardy, Barry; Harvey, James S.; Hillegass, Jedd; Honma, Masamitsu; Hsieh, Jui-Hua; Hsu, Chia-Wen; Hughes, Kathy; Johnson, Candice; Jolly, Robert; Jones, David; Kemper, Ray; Kenyon, Michelle O.; Kim, Marlene T.; Kruhlak, Naomi L.; Kulkarni, Sunil A.; Kuemmerer, Klaus; Leavitt, Penny; Majer, Bernhard; Masten, Scott; Miller, Scott; Moser, Janet; Mumtaz, Moiz; Muster, Wolfgang; Neilson, Louise; Oprea, Tudor I.; Patlewicz, Grace; Paulino, Alexandre; Lo Piparo, Elena; Powley, Mark; Quigley, Donald P.; Reddy, M. Vijayaraj; Richarz, Andrea-Nicole; Ruiz, Patricia; Schilter, Benoit; Serafimova, Rositsa; Simpson, Wendy; Stavitskaya, Lidiya; Stidl, Reinhard; Suarez-Rodriguez, Diana; Szabo, David T.; Teasdale, Andrew; Trejo-Martin, Alejandra; Valentin, Jean-Pierre; Vuorinen, Anna; Wall, Brian A.; Watts, Pete; White, Angela T.; Wichard, Joerg; Witt, Kristine L.; Woolley, Adam; Woolley, David; Zwickl, Craig; Hasselgren, Catrin 分享 收藏
Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity (vol 123, pg 237, 2015) French, John E.; Gatti, Daniel M.; Morgan, Daniel L.; Kissling, Grace E.; Shockley, Keith R.; Knudsen, Gabriel A.; Shepard, Kim G.; Price, Herman C.; King, Deborah; Witt, Kristine L.; Pedersen, Lars C.; Munger, Steven C.; Svenson, Karen L.; Churchill, Gary A. 分享 收藏
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Identification of Estrogen-Related Receptor α Agonists in the Tox21 Compound Library Lynch, Caitlin; Zhao, Jinghua; Huang, Ruili; Kanaya, Noriko; Bernal, Lauren; Hsieh, Jui-Hua; Auerbach, Scott S.; Witt, Kristine L.; Merrick, B. Alex; Chen, Shiuan; Teng, Christina T.; Xia, Menghang 分享 收藏