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Tip W. Loo

Eli Lilly

63H指数
136论文数
1.0W被引数
收录论文 64
发表时间
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A short cross-linker activates human P-glycoprotein missing a catalytic carboxylate
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2017-12-01
err2
PREAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Corrector VX-809 promotes interactions between cytoplasmic loop one and the first nucleotide-binding domain of CFTR
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2017-07-01
err46
PREAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-12-01
err44
errOAAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-07-01
err32
errOAAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformation
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2014-12-01
err57
PREAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Cysteines Introduced into Extracellular Loops 1 and 4 of Human P-Glycoprotein That Are Close Only in the Open Conformation Spontaneously Form a Disulfide Bond That Inhibits Drug Efflux and ATPase Activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2014-09-01
err15
errOAAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Identification of the Distance between the Homologous Halves of P-glycoprotein That Triggers the High/Low ATPase Activity Switch
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2014-03-01
err21
errOAAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bonds
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2014-03-01
err11
PREAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Locking Intracellular Helices 2 and 3 Together Inactivates Human P-glycoprotein
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2014-01-01
err22
errOAAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏
Corrector VX-809 stabilizes the first transmembrane domain of CFTR
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2013-09-01
err101
PREAI
errLoo, Tip W.; Bartlett, M. Claire; Clarke, David M.
err分享
err收藏
Human P-glycoprotein Contains a Greasy Ball-and-Socket Joint at the Second Transmission Interface
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-07-01
err48
errOAAI
errLoo, Tip W.; Bartlett, M. Claire; Clarke, David M.
err分享
err收藏
The ATPase Activity of the P-glycoprotein Drug Pump Is Highly Activated When the N-terminal and Central Regions of the Nucleotide-binding Domains Are Linked Closely Together
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2012-08-01
err64
errOAAI
errLoo, Tip W.; Bartlett, M. Claire; Detty, Michael R.; Clarke, David M.
err分享
err收藏
Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1)
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2012-07-01
err18
errOAAI
errOrchard, Alexandra; Schamerhorn, Gregory A.; Calitree, Brandon D.; Sawada, Geri A.; Loo, Tip W.; Bartlett, M. Claire; Clarke, David M.; Detty, Michael R.
err分享
err收藏
Chalcogenopyrylium Compounds as Modulators of the ATP-Binding Cassette Transporters P-Glycoprotein (P-gp/ABCB1) and Multidrug Resistance Protein 1 (MRP1/ABCC1)
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2012-05-10
err46
PREAI
errEbert, Sean P.; Wetzel, Bryan; Myette, Robert L.; Conseil, Gwenaelle; Cole, Susan P. C.; Sawada, Geri A.; Loo, Tip W.; Bartlett, M. Claire; Clarke, David M.; Detty, Michael R.
err分享
err收藏
Corrector-mediated rescue of misprocessed CFUR mutants can be reduced by the P-glycoprotein drug pump
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2012-02-01
err33
PREAI
errLoo, Tip W.; Bartlett, M. Claire; Shi, Li; Clarke, David M.
err分享
err收藏
Identification of Residues in the Drug Translocation Pathway of the Human Multidrug Resistance P-glycoprotein by Arginine Mutagenesis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2009-09-01
err90
errOAAI
errLoo, Tip W.; Bartlett, M. Claire; Clarke, David M.
err分享
err收藏
Rhodamine Inhibitors of P-Glycoprotein: An Amide/Thioamide Switch for ATPase Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2009-04-29
err75
errOAAI
errGannon, Michael K., II; Holt, Jason J.; Bennett, Stephanie M.; Wetzel, Bryan R.; Loo, Tip W.; Bartlett, M. Claire; Clarke, David M.; Sawada, Geri A.; Higgins, J. William; Tombline, Gregory; Raub, Thomas J.; Detty, Michael R.
err分享
err收藏
Processing mutations disrupt interactions between the nucleotide binding and transmembrane domains of P-glycoprotein and the cystic fibrosis transmembrane conductance regulator (CFTR)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2008-10-01
err68
errOAAI
errLoo, Tip W.; Bartlett, M. Claire; Clarke, David M.
err分享
err收藏
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2008-09-01
err28
errOAAI
errLoo, Tip W.; Bartlett, M. Claire; Clarke, David M.
err分享
err收藏
Mutational analysis of ABC proteins
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2008-08-01
err80
PREAI
errLoo, Tip W.; Clarke, David M.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
S
Susan P.C. Cole
H 指数: 77 · 论文数: 291
王
王莹 (Ying Wang)
H 指数: 74 · 论文数: 1.0K
D
David M. Clarke
H 指数: 70 · 论文数: 199
J
John W. Hanrahan
H 指数: 61 · 论文数: 209
M
Michael R. Detty
H 指数: 54 · 论文数: 334
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