未登录 CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety CDK4选择性抑制提高了临床前抗肿瘤疗效和安全性 Palmer, Cynthia L.; Boras, Britton; Pascual, Bernadette; Li, Na; Li, Danan; Garza, Scott; Huser, Nanni; Yuan, Jing Tang; Cianfrogna, Julie A.; Sung, Tae; Mcmillan, Elizabeth; Wei, Na; Carmody, Jason; Kang, Aubrey Nayeon; Darensburg, Seth; Dodd, Taran; Oakley, James, V; Solowiej, James; Nguyen, Lisa; Orr, Suvi T. M.; Chen, Ping; Johnson, Eric; Yu, Xiu; Diehl, Wade C.; Gallego, Gary M.; Jalaie, Mehran; Ferre, Rose Ann; Cho-Schultz, Sujin; Shen, Hong; Deal, Judith G.; Zhang, Qin; Baffi, Timothy R.; Xu, Meirong; Roh, Whijae; Lapira-Miller, Jennifer; Goudeau, Jerome; Yu, Yanke; Gupta, Rajat; Kim, Kimberly; Dann, Stephen G.; Kan, Zhengyan; Kath, John C.; Nair, Sajiv K.; Miller, Nichol; Murray, Brion W.; Nager, Andrew R.; Quinlan, Casey; Petroski, Matthew D.; Zhang, Cathy; Sacaan, Aida; Vanarsdale, Todd; Anders, Lars 分享 收藏
BBO-10203, a first-in-class, orally bioavailable, selective covalent small molecule that inhibits RAS- driven PI3Kalpha activity without affecting glucose metabolism Beltran, Pedro; Dhirendra, Simanshu; Xu, Rui; Chen, Ming; Czyzyk, Daniel; Donovan, Sofia; Feng, Siyu; Feng, Cindy; Fu, Lijuan; Lightstone, Felice; Lin, Ken; Maciag, Anna; Nissley, Dwight; Riegler, Erin; Sinkevicius, Kerstin; Stephen, Andrew; Stice, James; Turner, David; Wang, Bin; Wang, Keshi; Yang, Yue; Zhang, Cathy; McCormick, Frank; Wallace, Eli 分享 收藏
Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib Zhu, Zhou; Turner, Nicholas C.; Loi, Sherene; Andre, Fabrice; Martin, Miguel; Dieras, Veronique; Gelmon, Karen A.; Harbeck, Nadia; Zhang, Cathy; Cao, Joan Q.; Yan, Zhengming; Lu, Dongrui R.; Wei, Ping; VanArsdale, Todd L.; Rejto, Paul A.; Huang, Xin; Rugo, Hope S.; Loibl, Sibylle; Cristofanilli, Massimo; Finn, Richard S.; Liu, Yuan 分享 收藏
Long-read genome sequencing informs the molecular etiology of imprinting disorders Dixon, Katherine; Shen, Yaoqing; Chin, Hui-Lin; Gazzaz, Nour; Huynh, Stephanie; Chan, Simon; Zhang, Cathy; Culibrk, Luka; O'Neill, Kieran; Mungall, Karen; Mungall, Andrew; Moore, Richard; Gibson, William; Chanoine, Jean-Pierre; Boerkoel, Cornelius; Jones, Steven 分享 收藏
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer Freeman-Cook, Kevin D.; Hoffman, Robert L.; Behenna, Douglas C.; Boras, Britton; Carelli, Jordan; Diehl, Wade; Ferre, Rose Ann; He, You-Ai; Hui, Andrea; Huang, Buwen; Huser, Nanni; Jones, Rhys; Kephart, Susan E.; Lapek, John; McTigue, Michele; Miller, Nichol; Murray, Brion W.; Nagata, Asako; Nguyen, Lisa; Niessen, Sherry; Ninkovic, Sacha; O'Doherty, Inish; Ornelas, Martha A.; Solowiej, James; Sutton, Scott C.; Tran, Khanh; Tseng, Elaine; Visswanathan, Ravi; Xu, Meirong; Zehnder, Luke; Zhang, Qin; Zhang, Cathy; Dann, Stephen 分享 收藏
分享 收藏
分享 收藏
Fair Allocation of Scarce Medical Resources in the Time of Covid-19 新型冠状病毒肺炎时代稀缺医疗资源的公平配置 Emanuel, Ezekiel J.; Persad, Govind; Upshur, Ross; Thome, Beatriz; Parker, Michael; Glickman, Aaron; Zhang, Cathy; Boyle, Connor; Smith, Maxwell; Phillips, James P. 分享 收藏
Fc-effector function activity of the CXCR4 IgG1 antibody PF-06747143: a novel clinical candidate for the treatment of hematologic malignancies Pernasetti, Flavia; Liu, Shu-Hui; Yin, Gu; Pascual, Bernadette; Yan, Zhengming; Hallin, Max; Yafawi, Rolla; Zhang, Cathy; Fang, Connie; Wang, Wenlian; Lam, Justine; Spilker, Mary E.; Blasi, Eileen; Simmons, Brett; Huser, Nanni; Ho, Wei-Hsien; Lindquist, Kevin; Tran, Thomas-Toan; Kudaravalli, Jyothirmayee; Ma, Jing-Tyan; Jimenez, Gretchen; Barman, Ishita; Brown, Colleen; Chin, Sherman-Michael; Costa, Maria; Shelton, David; Smeal, Tod; Fantin, Valeria R. 分享 收藏
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies Liu, Shu-Hui; Gu, Yin; Pascual, Bernadette; Yan, Zhengming; Hallin, Max; Zhang, Cathy; Fan, Conglin; Wang, Wenlian; Lam, Justine; Spilker, Mary E.; Yafawi, Rolla; Blasi, Eileen; Simmons, Brett; Huser, Nanni; Ho, Wei-Hsien; Lindquist, Kevin; Tran, Thomas-Toan; Kudaravalli, Jyothirmayee; Ma, Jing-Tyan; Jimenez, Gretchen; Barman, Ishita; Brown, Colleen; Chin, Sherman Michael; Costa, Maria J.; Shelton, David; Smeal, Tod; Fantin, Valeria R.; Pernasetti, Flavia 分享 收藏
Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF06747143) in chronic lymphocytic leukemia 在慢性淋巴细胞白血病中使用新型anti-CXCR4 IgG1抗体 (PF06747143) 靶向CXCR4途径 Kashyap, Manoj K.; Amaya-Chanaga, Carlos I.; Kumar, Deepak; Simmons, Brett; Huser, Nanni; Gu, Yin; Hallin, Max; Lindquist, Kevin; Yafawi, Rolla; Choi, Michael Y.; Amine, Ale-Ali; Rassenti, Laura Z.; Zhang, Cathy; Liu, Shu-Hui; Smeal, Tod; Fantin, Valeria R.; Kipps, Thomas J.; Pernasetti, Flavia; Castro, Januario E. 分享 收藏
分享 收藏
分享 收藏
Identification of drug-sensitive Notch receptor alterations in human breast cancer Wang, Kai; Zhang, Qin; Li, Danan; Ching, Keith; Zhang, Cathy; Zheng, Xianxian; Ozeck, Mark; Shi, Stephanie; Li, Xiaorong; Wang, Hui; Rejto, Paul; Christensen, James; Olson, Peter 分享 收藏
分享 收藏
分享 收藏
Interrogating hedgehog pathway and smoothened inhibition by PF-04449913 in patient-derived acute myeloid leukemia models Jackson-Fisher, Amy; Whalen, Pamela; Elliott, Mark; McMahon, Melissa; Chen, Enhong; Zheng, Xianxian; Ozeck, Mark; Huang, Donghui; Lira, Paul; Lee, Joseph; Zhang, Cathy; Lam, Justine; Spilker, Mary; Deng, Shibing; Lappin, Patrick; Venne, Penny; Heinlein, Cynthia; Schairer, Annelie; McLachlan, Karen; VanArsdale, Todd 分享 收藏
A simplified approach to measuring thymidine kinase activity in cells, tumors, and blood as a biomarker of tumor proliferative potential Li, Wenlin; Kang, Xiaolin; Kindt, Kristian E.; Zhang, Cathy; Spilker, Mary; Berlinski, Pamela J.; Eisenbraun, Michael; Yan, Zhengming; Elliott, Mark; Arbuckle, J. Alan; Faria, Morse; Karnes, H. Thomas; O'Brien, Peter J. 分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
