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N

Nadezda A. Stepicheva

pennsylvania commonwealth system of higher education (pcshe)
H指数:17
被引数:1,104

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Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD-Like Pathology in Mice
AGING CELL
IF7.1
2025-02-170
OAAI
Chowdhury, Olivia; Bammidi, Sridhar; Gautam, Pooja; Babu, Vishnu Suresh; Liu, Haitao; Shang, Peng; Xin, Ying; Mahally, Emma; Nemani, Mihir; Koontz, Victoria; Lathrop, Kira; Kedziora, Katarzyna M.; Franks, Jonathan; Sun, Ming; Smith, Joshua W.; Devine, Lauren R.; Cole, Robert N.; Stepicheva, Nadezda; Strizhakova, Anastasia; Chattopadhyay, Sreya; Hose, Stacey; Zigler, Jacob Samuel; Sahel, Jose-Alain; Qian, Jiang; Guha, Prasun; Handa, James T.; Ghosh, Sayan; Sinha, Debasish
Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy

活化的cGAS/STING信号诱导早期糖尿病视网膜病变内皮细胞衰老

JCI INSIGHT
IF6.1
2023-06-2225
OA
Liu, Haitao; Ghosh, Sayan; Vaidya, Tanuja; Bammidi, Sridhar; Huang, Chao; Shang, Peng; Nair, Archana Padmanabhan; Chowdhury, Olivia; Stepicheva, Nadezda A.; Strizhakova, Anastasia; Hose, Stacey; Mitrousis, Nikolaos; Gadde, Santosh Gopikrishna; Thirumalesh, M. B.; Strassburger, Pamela; Widmer, Gabriella; Lad, Eleonora M.; Fort, Patrice E.; Sahel, Jose-Alain; Zigler Jr, J. Samuel; Sethu, Swaminathan; Westenskow, Peter D.; Proia, Alan D.; Sodhi, Akrit; Ghosh, Arkasubhra; Feenstra, Derrick; Sinha, Debasish
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy
NATURE COMMUNICATIONS
IF15.7
2022-10-1320
OAAI
Liu, Haitao; Stepicheva, Nadezda A.; Ghosh, Sayan; Shang, Peng; Chowdhury, Olivia; Daley, Rachel A.; Yazdankhah, Meysam; Gupta, Urvi; Hose, Stacey L.; Valapala, Mallika; Fitting, Christopher Scott; Strizhakova, Anastasia; Shan, Yang; Feenstra, Derrick; Sahel, Jose-Alain; Jayagopal, Ashwath; Handa, James T.; Zigler, J. Samuel, Jr.; Fort, Patrice E.; Sodhi, Akrit; Sinha, Debasish
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD

在干性AMD小鼠模型中，RPE中LCN2 (脂质运载蛋白2) 的增加会降低自噬并激活炎症小体-铁死亡过程

AUTOPHAGY
IF14.3
2022-04-2676
OA
Gupta, Urvi; Ghosh, Sayan; Wallace, Callen T.; Shang, Peng; Xin, Ying; Nair, Archana Padmanabhan; Yazdankhah, Meysam; Strizhakova, Anastasia; Ross, Mark A.; Liu, Haitao; Hose, Stacey; Stepicheva, Nadezda A.; Chowdhury, Olivia; Nemani, Mihir; Maddipatla, Vishnu; Grebe, Rhonda; Das, Manjula; Lathrop, Kira L.; Sahel, Jose-Alain; Zigler, J. Samuel, Jr.; Qian, Jiang; Ghosh, Arkasubhra; Sergeev, Yuri; Handa, James T.; St Croix, Claudette M.; Sinha, Debasish
βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells
COMMUNICATIONS BIOLOGY
IF5.1
2021-07-0820
OAAI
Shang, Peng; Stepicheva, Nadezda; Teel, Kenneth; McCauley, Austin; Fitting, Christopher Scott; Hose, Stacey; Grebe, Rhonda; Yazdankhah, Meysam; Ghosh, Sayan; Liu, Haitao; Strizhakova, Anastasia; Weiss, Joseph; Bhutto, Imran A.; Lutty, Gerard A.; Jayagopal, Ashwath; Qian, Jiang; Sahel, Jose-Alain; Zigler, J. Samuel, Jr.; Handa, James T.; Sergeev, Yuri; Rajala, Raju V. S.; Watkins, Simon; Sinha, Debasish
βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity
COMMUNICATIONS BIOLOGY
IF5.1
2021-02-248
OAAI
Ghosh, Sayan; Liu, Haitao; Yazdankhah, Meysam; Stepicheva, Nadezda; Shang, Peng; Vaidya, Tanuja; Hose, Stacey; Gupta, Urvi; Calderon, Michael Joseph; Hu, Ming-Wen; Nair, Archana Padmanabhan; Weiss, Joseph; Fitting, Christopher S.; Bhutto, Imran A.; Gadde, Santosh Gopi Krishna; Naik, Naveen Kumar; Jaydev, Chaitra; Lutty, Gerard A.; Handa, James T.; Jayagopal, Ashwath; Qian, Jiang; Sahel, Jose-Alain; Rajasundaram, Dhivyaa; Sergeev, Yuri; Zigler, J. Samuel; Sethu, Swaminathan; Watkins, Simon; Ghosh, Arkasubhra; Sinha, Debasish
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes
AUTOPHAGY
IF14.3
2021-01-1940
OAAI
Yazdankhah, Meysam; Ghosh, Sayan; Shang, Peng; Stepicheva, Nadezda; Hose, Stacey; Liu, Haitao; Chamling, Xitiz; Tian, Shenghe; Sullivan, Mara L. G.; Calderon, Michael Joseph; Fitting, Christopher S.; Weiss, Joseph; Jayagopal, Ashwath; Handa, James T.; Sahel, Jose-Alain; Zigler, J. Samuel, Jr.; Kinchington, Paul R.; Zack, Donald J.; Sinha, Debasish
Neutrophils homing into the retina trigger pathology in early age-related macular degeneration
COMMUNICATIONS BIOLOGY
IF5.1
2019-09-2042
OAAI
Ghosh, Sayan; Padmanabhan, Archana; Vaidya, Tanuja; Watson, Alan M.; Bhutto, Imran A.; Hose, Stacey; Shang, Peng; Stepicheva, Nadezda; Yazdankhah, Meysam; Weiss, Joseph; Das, Manjula; Gopikrishna, Santosh; Aishwarya; Yadav, Naresh; Berger, Thorsten; Mak, Tak W.; Xia, Shuli; Qian, Jiang; Lutty, Gerard A.; Jayagopal, Ashwath; Zigler, J. Samuel, Jr.; Sethu, Swaminathan; Handa, James T.; Watkins, Simon C.; Ghosh, Arkasubhra; Sinha, Debasish

研究方向

暂未获取到该数据
D
Debasish Sinha
H 指数:40论文数:164被引数:5,218
S
Stacey Hose
H 指数:24论文数:137被引数:1,783
S
Sayan Ghosh
H 指数:15论文数:49被引数:878
P
Peng Shang
H 指数:17论文数:70被引数:1,107
J
J. Samuel Zigler
H 指数:46论文数:221被引数:5,825
J
James T. Handa
H 指数:64论文数:347被引数:1.9万
H
Haitao Liu
H 指数:38论文数:237被引数:4,379
M
Meysam Yazdankhah
H 指数:20论文数:71被引数:3,769
J
José‐Alain Sahel
H 指数:100论文数:1,846被引数:4.1万
J
Joseph Weiss
H 指数:10论文数:28被引数:434