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J

James T. Handa

johns hopkins university school of medicine

64H指数
346论文数
1.9W被引数
收录论文 109
发表时间
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Correction: Examining the effects of cigarette smoke on mouse lens through a multi OMIC approach更正：通过多组学方法考察香烟烟雾对小鼠晶状体的影响
errScientific Reports
IF3.9
err2026-07-10
err0
errOAAI
errShahid Y. Khan; Muhammad Ali; Yura Jang; Taekyung Ryu; Andrew J. Schwab; Brian O. Ingram; Peter H. Cable; Chan Hyun Na; James T. Handa; S. Amer Riazuddin
err分享
err收藏
A critical role for mitochondrial dynamics in cigarette smoke condensate-induced RPE senescence香烟冷凝物诱导的RPE细胞衰老中，线粒体动力学发挥关键作用
errFree Radical Biology and Medicine
IF8.2
err2026-07-01
err0
errOAAI
errQi Zhou; Zunyi Zhang; Yinga Wu; Chunmin Dong; Chen-Chuan Wu; James T. Handa; Jing Ma; Shusheng Wang
err分享
err收藏
The internal limiting basement membrane inhibits functional engraftment of transplanted human retinal ganglion cells in vivo内部限制性基底层抑制移植人视网膜神经节细胞在体功能整合
errScience Translational Medicine
IF14.6
err2026-04-29
err0
PREAI
errErika A. Aguzzi; Stella Mary; Marzieh Mowlavi Vardanjani; Dayn Romero Godinez; Elizabeth Kimball; Behnoosh Bonakdar; Kevin Y. Zhang; Jian Du; Arumugam Nagalingam; William Yutzy; Sarah Quillen; Shreya Hariharakumar; Harry A. Quigley; Donald J. Zack; James T. Handa; Thomas V. Johnson
err分享
err收藏
In Vivo Characterization of ONL1204, a Small Peptide Inhibitor of the Fas Receptor, as a Potential Neuroprotective Therapy for Geographic Atrophy and Dry Age-Related Macular Degeneration体内评价ONL1204，一种Fas受体的小肽抑制剂，作为地理性萎缩和干性年龄相关性黄斑变性的潜在神经保护疗法
errBiomedicines
IF3.9
err2026-03-03
err0
errOAAI
errAndrew J. Kocab; Marisol Cano; Marianna Bacellar-Galdino; Jeffrey A. Jamison; William J. Brock; David N. Zacks; James T. Handa
err分享
err收藏
Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation年龄相关性黄斑变性和脑淀粉样血管病具有相似的由胆固醇-APOE-淀粉样β-补体介导的炎症病理。
errProgress in Retinal and Eye Research
IF14.7
err2026-02-16
err0
PREAI
errWhitney Stuard Sambhariya; Catherine Bowes Rickman; Patricia A. D’Amore; Giulia Corradetti; Gregory S. Hageman; Gareth R. Howell; Olivia J. Marola; Hemali Phatnani; Nancy J. Philp; Debasish Sinha; Christopher B. Toomey; Faith Stone; Charles Eberhart; James T. Handa
err分享
err收藏
Elevated Lactic Acid Levels in the Aqueous Humor May Be an Indicator of Uveal Melanoma房水中升高的乳酸水平可能是葡萄膜黑色素瘤的指标
errAmerican Journal of Ophthalmology
IF4.2
err2025-09-11
err0
PREAI
errSarah Miller; Marisol Cano; Ryan Kawalerski; Michan Daisy Shi; Akrit Sodhi; Shannath L. Merbs; Fatemeh Rajaii; Dan-Ning Hu; Charles G. Eberhart; James T. Handa
err分享
err收藏
A feasibility study of preclinical ocular x-ray FLASH radiotherapy眼科X射线FLASH放射治疗的临床前可行性研究
errinternational journal of radiation oncology biology physics
IF0
err2025-06-28
err0
PREAI
errDevin Miles; Daniel Sforza; Marisol Cano; Cornelia Peterson; Kathleen Gabrielson; John W. Wong; James Handa; Mohammad Rezaee
err分享
err收藏
Dissecting the biological complexity of age-related macular degeneration: Is it one disease, multiple separate diseases, or a spectrum?
errEXPERIMENTAL EYE RESEARCH
IF2.7
err2025-05-01
err0
errOAAI
errMiller, Jason M. L.; Thompson, Benjamin R.; Handa, James T.; Luthert, Philip; Chakravarthy, Usha; Csaky, Karl G.; Bird, Alan; Young, Benjamin K.; Iyengar, Sudha K.; Baek, Jiwon; Zouache, Moussa A.; Richards, Burt T.; Hageman, Gregory S.; Rodrigues, Gerry; Bharti, Kapil; Flannery, John G.; Gorin, Michael B.; Rickman, Catherine Bowes
err分享
err收藏
Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD-Like Pathology in Mice
errAGING CELL
IF7.1
err2025-02-17
err0
errOAAI
errChowdhury, Olivia; Bammidi, Sridhar; Gautam, Pooja; Babu, Vishnu Suresh; Liu, Haitao; Shang, Peng; Xin, Ying; Mahally, Emma; Nemani, Mihir; Koontz, Victoria; Lathrop, Kira; Kedziora, Katarzyna M.; Franks, Jonathan; Sun, Ming; Smith, Joshua W.; Devine, Lauren R.; Cole, Robert N.; Stepicheva, Nadezda; Strizhakova, Anastasia; Chattopadhyay, Sreya; Hose, Stacey; Zigler, Jacob Samuel; Sahel, Jose-Alain; Qian, Jiang; Guha, Prasun; Handa, James T.; Ghosh, Sayan; Sinha, Debasish
err分享
err收藏
OCT Changes Observed during the Progression of Early Age-Related Macular Degeneration
errOPHTHALMOLOGY SCIENCE
IF4.6
err2025-01-01
err0
errOAAI
errHeckenlaible, Nicolas J.; Toomey, Christopher B.; Handa, James T.
err分享
err收藏
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD
errNATURE COMMUNICATIONS
IF15.7
err2024-07-21
err2
errOAAI
errGhosh, Sayan; Sharma, Ruchi; Bammidi, Sridhar; Koontz, Victoria; Nemani, Mihir; Yazdankhah, Meysam; Kedziora, Katarzyna M.; Stolz, Donna Beer; Wallace, Callen T.; Cheng, Yu-Wei; Franks, Jonathan; Bose, Devika; Shang, Peng; Ambrosino, Helena M.; Dutton, James R.; Geng, Zhaohui; Montford, Jair; Ryu, Jiwon; Rajasundaram, Dhivyaa; Hose, Stacey; Sahel, Jose-Alain; Puertollano, Rosa; Finkel, Toren; Zigler, J. Samuel; Sergeev, Yuri; Watkins, Simon C.; Goetzman, Eric S.; Ferrington, Deborah A.; Flores-Bellver, Miguel; Kaarniranta, Kai; Sodhi, Akrit; Bharti, Kapil; Handa, James T.; Sinha, Debasish
err分享
err收藏
Significance of Social Determinants of Health in Tumor Presentation, Hospital Readmission, and Overall Survival in Ocular Oncology
errAMERICAN JOURNAL OF OPHTHALMOLOGY
IF4.2
err2024-04-01
err3
PREAI
errChoudhry, Hassaam S.; Patel, Aman M.; Nguyen, Helen N.; Kaleem, Mona A.; Handa, James T.
err分享
err收藏
A Clinical and Preclinical Assessment of Clinical Trials for Dry Age-Related Macular Degeneration
errOPHTHALMOLOGY SCIENCE
IF4.6
err2022-12-01
err6
errOAAI
errAbidi, Muhammad; Karrer, Erik; Csaky, Karl; Handa, James T.
err分享
err收藏
Microglia-Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
errCELLS
IF5.2
err2022-11-09
err13
errOAAI
errBoyce, Maeve; Xin, Ying; Chowdhury, Olivia; Shang, Peng; Liu, Haitao; Koontz, Victoria; Strizhakova, Anastasia; Nemani, Mihir; Hose, Stacey; Zigler, J. Samuel; Campbell, Matthew; Sinha, Debasish; Handa, James T.; Kaarniranta, Kai; Qian, Jiang; Ghosh, Sayan
err分享
err收藏
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy
errNATURE COMMUNICATIONS
IF15.7
err2022-10-13
err20
errOAAI
errLiu, Haitao; Stepicheva, Nadezda A.; Ghosh, Sayan; Shang, Peng; Chowdhury, Olivia; Daley, Rachel A.; Yazdankhah, Meysam; Gupta, Urvi; Hose, Stacey L.; Valapala, Mallika; Fitting, Christopher Scott; Strizhakova, Anastasia; Shan, Yang; Feenstra, Derrick; Sahel, Jose-Alain; Jayagopal, Ashwath; Handa, James T.; Zigler, J. Samuel, Jr.; Fort, Patrice E.; Sodhi, Akrit; Sinha, Debasish
err分享
err收藏
Characterization and identification of measurable endpoints in a mouse model featuring age-related retinal pathologies: a platform to test therapies
errLABORATORY INVESTIGATION
IF4.2
err2022-10-01
err3
errOAAI
errChoudhary, Mayur; Tayyari, Faryan; Handa, James T.; Malek, Goldis
err分享
err收藏
Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity
errAUTOPHAGY
IF14.3
err2022-08-13
err34
errOAAI
errDatta, Sayantan; Cano, Marisol; Satyanarayana, Ganesh; Liu, Tongyun; Wang, Lei; Wang, Jie; Cheng, Jie; Itoh, Kie; Sharma, Anjali; Bhutto, Imran; Kannan, Rangaramanujam; Qian, Jiang; Sinha, Debasish; Handa, James T.
err分享
err收藏
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD在干性AMD小鼠模型中，RPE中LCN2 (脂质运载蛋白2) 的增加会降低自噬并激活炎症小体-铁死亡过程
errAUTOPHAGY
IF14.3
err2022-04-26
err76
errOAAI
errGupta, Urvi; Ghosh, Sayan; Wallace, Callen T.; Shang, Peng; Xin, Ying; Nair, Archana Padmanabhan; Yazdankhah, Meysam; Strizhakova, Anastasia; Ross, Mark A.; Liu, Haitao; Hose, Stacey; Stepicheva, Nadezda A.; Chowdhury, Olivia; Nemani, Mihir; Maddipatla, Vishnu; Grebe, Rhonda; Das, Manjula; Lathrop, Kira L.; Sahel, Jose-Alain; Zigler, J. Samuel, Jr.; Qian, Jiang; Ghosh, Arkasubhra; Sergeev, Yuri; Handa, James T.; St Croix, Claudette M.; Sinha, Debasish
err分享
err收藏
Cell Death in AMD: The Rationale for Targeting Fas
errJOURNAL OF CLINICAL MEDICINE
IF2.9
err2022-01-25
err14
errOAAI
errZacks, David N.; Kocab, Andrew J.; Choi, Joanne J.; Gregory-Ksander, Meredith S.; Cano, Marisol; Handa, James T.
err分享
err收藏
Effects of fetal haemoglobin on systemic oxygenation in preterm infants and the development of retinopathy of prematurity PacIFiHER Report No. 2
errBRITISH JOURNAL OF OPHTHALMOLOGY
IF3.5
err2021-10-07
err7
PREAI
errJiramongkolchai, Kim; Repka, Michael X.; Tian, Jing; Aucott, Sue W.; Shepard, Jennifer; Collins, Megan; Clemens, Julia; Feller, Mia; Burd, Irina; Roizenblatt, Marina; Smith, Kerry; Arevalo, J. Fernando; Gehlbach, Peter L.; Handa, James T.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
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Gregg L. Semenza
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T
Tak W. Mak
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S
Simon C. Watkins
H 指数: 147 · 论文数: 1.1K
J
Julie R. Brahmer
H 指数: 115 · 论文数: 823
P
Peter A. Campochiaro
H 指数: 112 · 论文数: 541
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