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Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo. (vol 12, 3412, 2020) Stat5抑制剂IST5-002的临床开发前景：前列腺癌中高转录组特异性及体内低毒性。(vol 12, 3412, 2020) Maranto, Cristina; Udhane, Vindhya; Jia, Jing; Verma, Ranjit; Mueller-Newen, Gerhard; Laviolette, Peter S.; Pereckas, Michael; Sabharwal, Lavannya; Terhune, Scott; Pattabiraman, Nagarajan; Njar, Vincent C. O.; Imig, John D.; Wang, Liang; Nevalainen, Marja T. 分享 收藏
Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA 异常摄取，有限蛋白表达：肝巨噬细胞在合成mRNA的翻译中丢失 Lin, C; Kuzmanovic, A; Wang, N; Liao, LL; Ernst, S; Penners, C; Jans, A; Hammoor, T; Stach, PB; Peltzer, M; Volkert, I; Zechendorf, E; Hassan, R; Myllys, M; Liedtke, C; Herrmann, A; Chakraborty, G; Trautwein, C; Hengstler, J; Mueller-Newen, G; Wang, JQ; Ghallab, A; Bartneck, M 分享 收藏
Engineering Mesoscopic 3D Tumor Models with a Self-Organizing Vascularized Matrix (Adv. Mater. 5/2024) De Lorenzi, Federica; Hansen, Nadja; Theek, Benjamin; Daware, Rasika; Motta, Alessandro; Breuel, Saskia; Nasehi, Ramin; Baumeister, Julian; Schoeneberg, Jan; Stojanovic, Natalija; von Stillfried, Saskia; Vogt, Michael; Mueller-Newen, Gerhard; Maurer, Jochen; Sofias, Alexandros Marios; Lammers, Twan; Fischer, Horst; Kiessling, Fabian 分享 收藏
Engineering Mesoscopic 3D Tumor Models with a Self-Organizing Vascularized Matrix De Lorenzi, Federica; Hansen, Nadja; Theek, Benjamin; Daware, Rasika; Motta, Alessandro; Breuel, Saskia; Nasehi, Ramin; Baumeister, Julian; Schoeneberg, Jan; Stojanovic, Natalija; von Stillfried, Saskia; Vogt, Michael; Mueller-Newen, Gerhard; Maurer, Jochen; Sofias, Alexandros Marios; Lammers, Twan; Fischer, Horst; Kiessling, Fabian 分享 收藏
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Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization 制瘤素M调节骨髓中的造血干细胞 (HSC) 壁ni以限制HSC动员 Bisht, Kavita; McGirr, Crystal; Lee, Seo-Youn; Tseng, Hsu-Wen; Fleming, Whitney; Alexander, Kylie A.; Matsumoto, Taichi; Barbier, Valerie; Sims, Natalie A.; Mueller-Newen, Gerhard; Winkler, Ingrid G.; Bonig, Halvard; Levesque, Jean-Pierre 分享 收藏
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Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-in-Silico Approach Combining In Vitro Experiments and Machine Learning (vol 9, 393, 2018) Zechendorf, Elisabeth; Vassen, Phillip; Zhang, Jieyi; Hallawa, Ahmed; Martincuks, Antons; Krenkel, Oliver; Mueller-Newen, Gerhard; Schuerholz, Tobias; Simon, Tim-Philipp; Marx, Gernot; Ascheid, Gerd; Schmeink, Anke; Dartmann, Guido; Thiemermann, Christoph; Martin, Lukas 分享 收藏
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis Zechendorf, Elisabeth; O'Riordan, Caroline E.; Stiehler, Lara; Wischmeyer, Natalie; Chiazza, Fausto; Collotta, Debora; Denecke, Bernd; Ernst, Sabrina; Mueller-Newen, Gerhard; Coldewey, Sina M.; Wissuwa, Bianka; Collino, Massimo; Simon, Tim-Philipp; Schuerholz, Tobias; Stoppe, Christian; Marx, Gernot; Thiemermann, Christoph; Martin, Lukas 分享 收藏
Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells Hollmann, Jonathan; Brecht, Johanna; Goetzke, Roman; Franzen, Julia; Selich, Anton; Schmidt, Marco; Eipel, Monika; Ostrowska, Alina; Hapala, Jan; Fernandez-Rebollo, Eduardo; Mueller-Newen, Gerhard; Rothe, Michael; Eggermann, Thomas; Zenke, Martin; Wagner, Wolfgang 分享 收藏
Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis Puelles, Victor G.; Fleck, David; Ortz, Lena; Papadouri, Stella; Strieder, Thiago; Boehner, Alexander M. C.; van der Wolde, James W.; Vogt, Michael; Saritas, Turgay; Kuppe, Christoph; Fuss, Astrid; Menzel, Sylvia; Klinkhammer, Barbara M.; Mueller-Newen, Gerhard; Heymann, Felix; Decker, Leon; Braun, Fabian; Kretz, Oliver; Huber, Tobias B.; Susaki, Etsuo A.; Ueda, Hiroki R.; Boor, Peter; Floege, Juergen; Kramann, Rafael; Kurts, Christian; Bertram, John F.; Spehr, Marc; Nikolic-Paterson, David J.; Moeller, Marcus J. 分享 收藏
Stem cell persistence in CML is mediated by extrinsically activated JAK1-STAT3 signaling Kuepper, Maja Kim; Buetow, Marlena; Herrmann, Oliver; Ziemons, Janine; Chatain, Nicolas; Maurer, Angela; Kirschner, Martin; Maie, Tiago; Costa, Ivan G.; Eschweiler, Joerg; Koschmieder, Steffen; Bruemmendorf, Tim H.; Mueller-Newen, Gerhard; Schemionek, Mirle 分享 收藏
JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation Czech, Julia; Cordua, Sabrina; Weinbergerova, Barbora; Baumeister, Julian; Crepcia, Assja; Han, Lijuan; Maie, Tiago; Costa, Ivan G.; Denecke, Bernd; Maurer, Angela; Schubert, Claudia; Feldberg, Kristina; Gezer, Deniz; Bruemmendorf, Tim H.; Mueller-Newen, Gerhard; Mayer, Jiri; Racil, Zdenek; Kubesova, Blanka; Knudsen, Trine; Sorensen, Anders L.; Holmstrom, Morten; Kjaer, Lasse; Skov, Vibe; Larsen, Thomas Stauffer; Hasselbalch, Hans C.; Chatain, Nicolas; Koschmieder, Steffen 分享 收藏
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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma Sonntag, Roland; Giebeler, Nives; Nevzorova, Yulia A.; Bangen, Joerg-Martin; Fahrenkamp, Dirk; Lambertz, Daniela; Haas, Ute; Hu, Wei; Gassier, Nikolaus; Cubero, Francisco Javier; Mueller-Newen, Gerhard; Abdallan, Ali T.; Weiskirchen, Ralf; Ticconi, Fabio; Costa, Ivan G.; Barbacid, Mariano; Trautwein, Christian; Liedtke, Christian 分享 收藏
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target (vol 20, pg 785, 2017) Schneider, Rebekka K.; Mullally, Ann; Dugourd, Aurelien; Peisker, Fabian; Hoogenboezem, Remco; Van Strien, Paulina M. H.; Bindels, Eric M.; Heckl, Dirk; Busche, Guntram; Fleck, David; Mueller-Newen, Gerhard; Wongboonsin, Janewit; Ferreira, Monica Ventura; Puelles, Victor G.; Saez-Rodriguez, Julio; Ebert, Benjamin L.; Humphreys, Benjamin D.; Kramann, Rafael 分享 收藏
Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription Buetepage, Mareike; Preisinger, Christian; von Kriegsheim, Alexander; Scheufen, Anja; Lausberg, Eva; Li, Jinyu; Kappes, Ferdinand; Feederle, Regina; Ernst, Sabrina; Eckei, Laura; Krieg, Sarah; Mueller-Newen, Gerhard; Rossetti, Giulia; Feijs, Karla L. H.; Verheugd, Patricia; Luescher, Bernhard 分享 收藏
Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning 硫酸乙酰肝素诱导小鼠心肌细胞坏死性凋亡: 结合体外实验和机器学习的医学计算机方法 Zechendorf, Elisabeth; Vassen, Phillip; Zhang, Jieyi; Hallawa, Ahmed; Martincuks, Antons; Krenkel, Oliver; Mueller-Newen, Gerhard; Schuerholz, Tobias; Simon, Tim-Philipp; Marx, Gernot; Ascheid, Gerd; Schmeink, Anke; Dartmann, Guido; Thiemermann, Christoph; Martin, Lukas 分享 收藏
Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies Abagnale, Giulio; Sechi, Antonio; Steger, Michael; Zhou, Qihui; Kuo, Chao-Chung; Aydin, Guelcan; Schalla, Carmen; Mueller-Newen, Gerhard; Zenke, Martin; Costa, Ivan G.; van Rijn, Patrick; Gillner, Arnold; Wagner, Wolfgang 分享 收藏
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