William Sheffler - Publications, H-index & Citations

William Sheffler

Department of Biochemistry

36H指数

83论文数

1.2W被引数

收录论文 14

发表时间

Bond-centric modular design of protein assemblies 以键为中心的蛋白质组装模块化设计

Nature Materials

IF38.5

2025-07-31

OAAI

Shunzhi Wang; Andrew Favor; Ryan D. Kibler; Joshua M. Lubner; Andrew J. Borst; Nicolas Coudray; Rachel L. Redler; Huat Thart Chiang; William Sheffler; Yang Hsia; Neville P. Bethel; Zhe Li; Damian C. Ekiert; Gira Bhabha; Lilo D. Pozzo; David Baker

De novo design of pH-responsive self-assembling helical protein filaments

NATURE NANOTECHNOLOGY

IF34.9

2024-04-03

OAAI

Shen, Hao; Lynch, Eric M.; Akkineni, Susrut; Watson, Joseph L.; Decarreau, Justin; Bethel, Neville P.; Benna, Issa; Sheffler, William; Farrell, Daniel; Dimaio, Frank; Derivery, Emmanuel; De Yoreo, James J.; Kollman, Justin; Baker, David

Accurate computational design of three-dimensional protein crystals

NATURE MATERIALS

IF38.5

2023-10-16

OAAI

Li, Zhe; Wang, Shunzhi; Nattermann, Una; Bera, Asim K.; Borst, Andrew J.; Yaman, Muammer Y.; Bick, Matthew J.; Yang, Erin C.; Sheffler, William; Lee, Byeongdu; Seifert, Soenke; Hura, Greg L.; Nguyen, Hannah; Kang, Alex; Dalal, Radhika; Lubner, Joshua M.; Hsia, Yang; Haddox, Hugh; Courbet, Alexis; Dowling, Quinton; Miranda, Marcos; Favor, Andrew; Etemadi, Ali; Edman, Natasha I.; Yang, Wei; Weidle, Connor; Sankaran, Banumathi; Negahdari, Babak; Ross, Michael B.; Ginger, David S.; Baker, David

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains 通过隐性跨膜结构域的负设计改善设计的蛋白质组装体的分泌

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-08

OAAI

Wang, Jing Yang (John); Khmelinskaia, Alena; Sheffler, William; Miranda, Marcos C.; Antanasijevic, Aleksandar; Borst, Andrew J.; V. Torres, Susana; Shu, Chelsea; Hsia, Yang; Nattermann, Una; Ellis, Daniel; Walkey, Carl; Ahlrichs, Maggie; Chan, Sidney; Kang, Alex; Nguyen, Hannah; Sydeman, Claire; Sankaran, Banumathi; Wu, Mengyu; Bera, Asim K.; Carter, Lauren; Fiala, Brooke; Murphy, Michael; Baker, David; Ward, Andrew B.; King, Neil P.

Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks

CHEMISTRY OF MATERIALS

IF7

2022-10-25

OAAI

Said, Meerit Y.; Kang, Christine S.; Wang, Shunzhi; Sheffler, William; Salveson, Patrick J.; Bera, Asim K.; Kang, Alex; Nguyen, Hannah; Ballard, Ryanne; Li, Xinting; Bai, Hua; Stewart, Lance; Levine, Paul; Baker, David

Design of multi-scale protein complexes by hierarchical building block fusion

NATURE COMMUNICATIONS

IF15.7

2021-04-16

OAAI

Hsia, Yang; Mout, Rubul; Sheffler, William; Edman, Natasha, I; Vulovic, Ivan; Park, Young-Jun; Redler, Rachel L.; Bick, Matthew J.; Bera, Asim K.; Courbet, Alexis; Kang, Alex; Brunette, T. J.; Nattermann, Una; Tsai, Evelyn; Saleem, Ayesha; Chow, Cameron M.; Ekiert, Damian; Bhabha, Gira; Veesler, David; Baker, David

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

ELIFE

IF0

2020-08-04

127

OAAI

Ueda, George; Antanasijevic, Aleksandar; Fallas, Jorge A.; Sheffler, William; Copps, Jeffrey; Ellis, Daniel; Hutchinson, Geoffrey B.; Moyer, Adam; Yasmeen, Anila; Tsybovsky, Yaroslav; Park, Young-Jun; Bick, Matthew J.; Sankaran, Banumathi; Gillespie, Rebecca A.; Brouwer, Philip J. M.; Zwart, Peter H.; Veesler, David; Kanekiyo, Masaru; Graham, Barney S.; Sanders, Rogier W.; Moore, John P.; Klasse, Per Johan; Ward, Andrew B.; King, Neil P.; Baker, David

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

NATURE COMMUNICATIONS

IF15.7

2019-09-19

158

OAAI

Brouwer, Philip J. M.; Antanasijevic, Aleksandar; Berndsen, Zachary; Yasmeen, Anila; Fiala, Brooke; Bijl, Tom Pl; Bontjer, Ilja; Bale, Jacob B.; Sheffler, William; Allen, Joel D.; Schorcht, Anna; Burgers, Judith A.; Camacho, Miguel; Ellis, Daniel; Cottrell, Christopher A.; Behrens, Anna-Janina; Catalano, Marco; Del Moral-Sanchez, Ivan; Ketas, Thomas J.; LaBranche, Celia; van Gils, Marit J.; Sliepen, Kwinten; Stewart, Lance J.; Crispin, Max; Montefiori, David C.; Baker, David; Moore, John P.; Klasse, Per Johan; Ward, Andrew B.; King, Neil P.; Sanders, Rogier W.

Multi-input chemical control of protein dimerization for programming graded cellular responses

NATURE BIOTECHNOLOGY

IF41.7

2019-09-09

OAAI

Foight, Glenna Wink; Wang, Zhizhi; Wei, Cindy T.; Greisen, Per, Jr.; Warner, Katrina M.; Cunningham-Bryant, Daniel; Park, Keunwan; Brunette, T. J.; Sheffler, William; Baker, David; Maly, Dustin J.

Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-01-19

OAAI

Sahasrabuddhe, Aniruddha; Hsia, Yang; Busch, Florian; Sheffler, William; King, Neil P.; Baker, David; Wysocki, Vicki H.

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site

NATURE BIOTECHNOLOGY

IF41.7

2017-06-12

109

OAAI

Strauch, Eva-Maria; Bernard, Steffen M.; La, David; Bohn, Alan J.; Lee, Peter S.; Anderson, Caitlin E.; Nieusma, Travis; Holstein, Carly A.; Garcia, Natalie K.; Hooper, Kathryn A.; Ravichandran, Rashmi; Nelson, Jorgen W.; Sheffler, William; Bloom, Jesse D.; Lee, Kelly K.; Ward, Andrew B.; Yager, Paul; Fuller, Deborah H.; Wilson, Ian A.; Baker, David

Computational design of a homotrimeric metalloprotein with a trisbipyridyl core

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-12-08

OAAI

Mills, Jeremy H.; Sheffler, William; Ener, Maraia E.; Almhjell, Patrick J.; Oberdorfer, Gustav; Pereira, Jose Henrique; Parmeggiani, Fabio; Sankaran, Banumathi; Zwart, Peter H.; Baker, David

Symmetry-Based Design and Structure of Self-Assembling Protein Cages and Nanomaterials

BIOPHYSICAL JOURNAL

IF3.1

2014-01-01

OAAI

Lai, Yen-Ting; King, Neil P.; Sheffler, William; McNamara, Dan E.; Bale, Jacob B.; Baker, David; Yeates, Todd O.

Structure prediction for CABP7 targets using extensive all-atom refinement with Rosetta@home

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2007-01-01

198

PREAI

Das, Rhiju; Bin Qian; Raman, Srivatsan; Vernon, Robert; Thompson, James; Bradley, Philip; Khare, Sagar; Tyka, Michael D.; Bhat, Divya; Chivian, Dylan; Kim, David E.; Sheffler, William H.; Malmstrom, Lars; Wollacott, Andrew M.; Wang, Chu; Andre, Ingemar; Baker, David

研究方向