未登录Targeting Menin in T-Lineage Acute Lymphoblastic Leukemia靶向Menin在T系急性淋巴细胞白血病中的应用
Shimamoto, Kathryn Kimi; Karaoglu, Arda Arda; Chan, Zachary; Giordano, Giorgia; Eisfelder, Bartholomew; Cheng, Jason Xiaojun; Youshanlouei, Hamed; Shah, Syed; Patel, Anand Ashwin; Duvall, Adam S.; Burrows, Francis; Kessler, Linda; Drazer, Michael W.; Odenike, Olatoyosi; Thirman, Michael J.; Stock, Wendy; Saygin, Caner .png)
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收藏Combined Use of Ziftomenib and Selinexor Is Effective in NPM1 Mutant Acute Myeloid LeukemiaZiftomenib与Selinexor的联合使用对NPM1突变急性髓系白血病有效Dhiman, Sandhya; Uddin, Md. Hafiz; Dhillon, Vikram; Aguilar, Jeff Justin; Aboukameel, Amro; Khan, Husain; Bannoura, Sahar; Yang, Jay; Dyson, Gregory; Buck, Steven; Azmi, Asfar; Polin, Lisa; Burrows, Francis; Kessler, Linda; Maciejewski, Jaroslaw; Balasubramanian, Suresh Kumar 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapiesFigarol, Sarah; Delahaye, Celia; Gence, Remi; Doussine, Aurelia; Cerapio, Juan Pablo; Brachais, Mathylda; Tardy, Claudine; Bery, Nicolas; Asslan, Raghda; Colinge, Jacques; Villemin, Jean-Philippe; Maraver, Antonio; Ferrer, Irene; Paz-Ares, Luis; Kessler, Linda; Burrows, Francis; Lajoie-Mazenc, Isabelle; Dongay, Vincent; Morin, Clara; Florent, Amelie; Pagano, Sandra; Taranchon-Clermont, Estelle; Casanova, Anne; Pradines, Anne; Mazieres, Julien; Favre, Gilles; Calvayrac, Olivier 分享 收藏 Evolutionary dynamics of tipifarnib in HRAS mutated head and neck squamous cell carcinomaJagadeeshan, Sankar; Suryamohan, Kushal; Shin, Nara; Mathukkada, Sooraj; Boyko, Alexandra; Melikhova, Daria; Tsareva, Anastasia; Yunusova, Leysan; Pravdivtseva, Ekaterina; Stupichev, Danil; Shaposhnikov, Kirill; Peterson, Angela; Bednyagin, Lev; Shugaev-Mendosa, Eduardo; Kessler, Linda; Burrows, Francis; Ho, Alan L.; Agrawal, Nishant; Pearson, Alexander T.; Izumchenko, Evgeny; Cole, Grayson; Elkabets, Moshe; Rosenberg, Ari J. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR ActivitySmith, Alison E.; Chan, Stacia; Wang, Zhiyong; Mccloskey, Asako; Reilly, Quinn; Wang, Jayden Z.; Patel, Hetika Vora; Koshizuka, Keiichi; Soifer, Harris S.; Kessler, Linda; Dayoub, Ashley; Villaflor, Victoria; Adkins, Douglas R.; Bruce, Justine Y.; Ho, Alan L.; Perez, Cesar A.; Hanna, Glenn J.; Hernandez, Amaya Gasco; Saunders, Andrew; Dale, Stephen; Gutkind, J. Silvio; Burrows, Francis; Malik, Shivani 分享 收藏 Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with MLL rearrangement or NPM1 mutation to venetoclaxRausch, Johanna; Dzama, Margarita M.; Dolgikh, Nadezda; Stiller, Hanna L.; Bohl, Stephan R.; Lahrmann, Catharina; Kunz, Kerstin; Kessler, Linda; Echchannaoui, Hakim; Chen, Chun-Wei; Kindler, Thomas; Doehner, Konstanze; Burrows, Francis; Theobald, Matthias; Sasca, Daniel; Kuehn, Michael W. M. 分享 收藏 分享 收藏 分享 收藏 Mutated HRAS Activates YAP1-AXL Signaling to Drive Metastasis of Head and Neck CancerJagadeeshan, Sankar; Prasad, Manu; Badarni, Mai; Ben-Lulu, Talal; Liju, Vijayasteltar Belsamma; Mathukkada, Sooraj; Saunders, Claire; Shnerb, Avital Beeri; Zorea, Jonathan; Yegodayev, Ksenia M.; Wainer, Monica; Vtorov, Liza; Allon, Irit; Cohen, Ofir; Gausdal, Gro; Friedmann-Morvinski, Dinorah; Cheong, Sok Ching; Ho, Alan L.; Rosenberg, Ari J.; Kessler, Linda; Burrows, Francis; Kong, Dexin; Grandis, Jennifer R.; Gutkind, J. Silvio; Elkabets, Moshe 分享 收藏 Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1Fiskus, Warren; Daver, Naval; Boettcher, Steffen; Mill, Christopher P.; Sasaki, Koji; Birdwell, Christine E.; Davis, John A.; Das, Kaberi; Takahashi, Koichi; Kadia, Tapan M.; DiNardo, Courtney D.; Burrows, Francis; Loghavi, Sanam; Khoury, Joseph D.; Ebert, Benjamin L.; Bhalla, Kapil N. 分享 收藏 分享 收藏 The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of actionChen, Rong; Tsai, Jennifer; Thompson, Philip A.; Chen, Yuling; Xiong, Ping; Liu, Chaomei; Burrows, Francis; Sivina, Mariela; Burger, Jan A.; Keating, Michael J.; Wierda, William G.; Plunkett, William 分享 收藏 Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell CarcinomasGilardi, Mara; Wang, Zhiyong; Proietto, Marco; Chilla, Anastasia; Calleja-Valera, Juan Luis; Goto, Yusuke; Vanoni, Marco; Janes, Matthew R.; Mikulski, Zbigniew; Gualberto, Antonio; Molinolo, Alfredo A.; Ferrara, Napoleone; Gutkind, J. Silvio; Burrows, Francis 分享 收藏 
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