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YAP/TAZ activity in PDGFRα-expressing alveolar fibroblasts modulates AT2 proliferation through Wnt4 YAP/TAZ在表达PDGFRα的肺泡成纤维细胞中的活性通过Wnt4调控AT2细胞增殖。 Song, Jane Y.; Wehbe, Fabien; Wong, Aaron K.; Hall, Ben M.; Heiden, Jason A. Vander; Brightbill, Hans D.; Arron, Joseph R.; Garfield, David A.; Dey, Anwesha; Rock, Jason R. 分享 收藏
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Early Stage Preclinical Formulation Strategies to Alter the Pharmacokinetic Profile of Two Small Molecule Therapeutics An, Le; De Bruyn, Tom; Pang, Jodie; Ubhayakar, Savita; Salphati, Laurent; Zhang, Xing; Liu, Liling; Li, Ruina; Chan, Bryan; Dey, Anwesha; Levy, Elizabeth S. 分享 收藏
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BAP1 promotes osteoclast function by metabolic reprogramming Rohatgi, Nidhi; Zou, Wei; Li, Yongjia; Cho, Kevin; Collins, Patrick L.; Tycksen, Eric; Pandey, Gaurav; Deselm, Carl J.; Patti, Gary J.; Dey, Anwesha; Teitelbaum, Steven L. 分享 收藏
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance 变构泛TEAD抑制剂阻断致癌YAP/TAZ信号传导并克服KRAS G12C抑制剂抗性 Hagenbeek, Thijs J. J.; Zbieg, Jason R. R.; Hafner, Marc; Mroue, Rana; Lacap, Jennifer A. A.; Sodir, Nicole M. M.; Noland, Cameron L. L.; Afghani, Shervin; Kishore, Ayush; Bhat, Kamakoti P. P.; Yao, Xiaosai; Schmidt, Stephen; Clausen, Saundra; Steffek, Micah; Lee, Wendy; Beroza, Paul; Martin, Scott; Lin, Eva; Fong, Rina; Di Lello, Paola; Kubala, Marta H. H.; Yang, Michelle N. -Y.; Lau, Jeffrey T. T.; Chan, Emily; Arrazate, Alfonso; An, Le; Levy, Elizabeth; Lorenzo, Maria N. N.; Lee, Ho-June; Pham, Trang H. H.; Modrusan, Zora; Zang, Richard; Chen, Yi-Chen; Kabza, Michal; Ahmed, Musaddeque; Li, Jason; Chang, Matthew T. T.; Maddalo, Danilo; Evangelista, Marie; Ye, Xin; Crawford, James J. J.; Dey, Anwesha 分享 收藏
TEAD Proteins Associate With DNA Repair Proteins to Facilitate Cellular Recovery From DNA Damage Calses, Philamer C.; Pham, Victoria C.; Guarnaccia, Alissa D.; Choi, Meena; Verschueren, Erik; Bakker, Sietske T.; Pham, Trang H.; Hinkle, Trent; Liu, Chad; Chang, Matthew T.; Kljavin, Noelyn; Bakalarski, Corey; Haley, Benjamin; Zou, Jianing; Yan, Cuicui; Song, Xia; Lin, Xiaoyan; Rowntree, Rebecca; Ashworth, Alan; Dey, Anwesha; Lill, Jennie R. 分享 收藏
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Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways Pham, Trang H.; Hagenbeek, Thijs J.; Lee, Ho-June; Li, Jason; Rose, Christopher M.; Lin, Eva; Yu, Mamie; Martin, Scott E.; Piskol, Robert; Lacap, Jennifer A.; Sampath, Deepak; Pham, Victoria C.; Modrusan, Zora; Lill, Jennie R.; Klijn, Christiaan; Malek, Shiva; Chang, Matthew T.; Dey, Anwesha 分享 收藏
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Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer Carbone, Michele; Harbour, J. William; Brugarolas, James; Bononi, Angela; Pagano, Ian; Dey, Anwesha; Krausz, Thomas; Pass, Harvey, I; Yang, Haining; Gaudino, Giovanni 分享 收藏
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Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure Zou, Wei; Rohatgi, Nidhi; Brestoff, Jonathan R.; Moley, John R.; Li, Yongjia; Williams, Jesse W.; Alippe, Yael; Pan, Hua; Pietka, Terri A.; Mbalaviele, Gabriel; Newberry, Elizabeth P.; Davidson, Nicholas O.; Dey, Anwesha; Shoghi, Kooresh, I; Head, Richard D.; Wickline, Samuel A.; Randolph, Gwendalyn J.; Abumrad, Nada A.; Teitelbaum, Steven L. 分享 收藏
y The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma Lee, Ho-June; Trang Pham; Chang, Matthew T.; Barnes, Dwight; Cai, Allen G.; Noubade, Rajkumar; Totpal, Klara; Chen, Xu; Tran, Christopher; Hagenbeek, Thijs; Wu, Xiumin; Eastham-Anderson, Jeff; Tao, Janet; Lee, Wyne; Bastian, Boris C.; Carbone, Michele; Webster, Joshua D.; Dey, Anwesha 分享 收藏
TAZ is required for lung alveolar epithelial cell differentiation after injury Sun, Tianhe; Huang, Zhiyu; Zhang, Hua; Posner, Clara; Jia, Guiquan; Ramalingam, Thirumalai R.; Xu, Min; Brightbill, Hans; Egen, Jackson G.; Dey, Anwesha; Arron, Joseph R. 分享 收藏
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The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma 肿瘤抑制因子BAP1与BRAFV600E协同促进皮肤黑色素瘤的肿瘤形成 Webster, Joshua D.; Pham, Trang H.; Wu, Xiumin; Hughes, Nicolas W.; Li, Zhongwu; Totpal, Klara; Lee, Ho-June; Calses, Philamer C.; Chaurushiya, Mira S.; Stawiski, Eric W.; Modrusan, Zora; Chang, Matthew T.; Tran, Christopher; Lee, Wyne P.; Chalasani, Sreedevi; Hung, Jeffrey; Sharma, Neeraj; Chan, Sara; Hotzel, Kathy; Talevich, Eric; Shain, Alan; Xu, Mengshu; Lill, Jennie; Dixit, Vishva M.; Bastian, Boris C.; Dey, Anwesha 分享 收藏
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