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收藏分享 收藏 A cancer persistent DNA repair circuit driven by MDM2, MDM4 (MDMX), and mutant p53 for recruitment of MDC1 and 53BP1 on chromatin由MDM2、MDM4（MDMX）和突变型p53驱动的癌症持续性DNA修复通路，用于招募MDC1和53BP1到染色质上
Ellison, Viola; Polotskaia, Alla; Xiao, Gu; Leybengrub, Pamella; Lee, Rusia; Qiu, Weigang; Hendrickson, Ronald C.; Hu, Wenwei; Bargonetti, Jill 分享 收藏 Lipogenic enzyme FASN promotes mutant p53 accumulation and gain-of-function through palmitoylation脂生成酶FASN通过棕榈酰化促进突变型p53的积累和获得性功能。Liu, Juan; Shen, Yiyun; Liu, Jie; Xu, Dandan; Chang, Chun-Yuan; Wang, Jianming; Zhou, Jason; Haffty, Bruce G.; Zhang, Lanjing; Bargonetti, Jill; De, Subhajyoti; Hu, Wenwei 分享 收藏 分享 收藏 Fruquintinib plus paclitaxel versus placebo plus paclitaxel for gastric or gastroesophageal junction adenocarcinoma: the randomized phase 3 FRUTIGA trialFruquintinib联合紫杉醇与安慰剂联合紫杉醇治疗胃或胃食管交界处腺癌的比较: FRUTIGA随机3期试验Wang, Feng; Shen, Lin; Guo, Weijian; Liu, Tianshu; Li, Jin; Qin, Shukui; Bai, Yuxian; Chen, Zhendong; Wang, Jufeng; Pan, Yueyin; Shu, Yongqian; Zhao, Fuyou; Cheng, Ying; Ye, Feng; Gu, Kangsheng; Zhang, Tao; Pan, Hongming; Zhong, Haijun; Zhou, Fuxiang; Qin, Yanru; Yang, Lei; Mao, Weidong; Li, Qiu; Dai, Wenxiang; Li, Wei; Wang, Shubin; Tang, Yong; Ma, Dong; Yin, Xianli; Deng, Yanhong; Yuan, Ying; Li, Man; Hu, Wenwei; Chen, Donghui; Li, Guoxin; Liu, Qiqi; Tan, Panfeng; Fan, Songhua; Shi, Michael; Su, Weiguo; Xu, Rui-Hua 分享 收藏 分享 收藏 Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in miceYang, Xue; Wang, Jianming; Chang, Chun-Yuan; Zhou, Fan; Liu, Juan; Xu, Huiting; Ibrahim, Maria; Gomez, Maria; Guo, Grace L.; Liu, Hao; Zong, Wei-Xing; Wondisford, Fredric E.; Su, Xiaoyang; White, Eileen; Feng, Zhaohui; Hu, Wenwei 分享 收藏 p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndromeWang, Jianming; Chang, Chun-Yuan; Yang, Xue; Zhou, Fan; Liu, Juan; Bargonetti, Jill; Zhang, Lanjing; Xie, Ping; Feng, Zhaohui; Hu, Wenwei 分享 收藏 Autophagy and MEK inhibition promotes ferroptosis in liver kinase B1 (Lkb1)-deficient Kras-driven lung tumorsBhatt, Vrushank; Lan, Taijin; Wang, Wenping; Kong, Jerry; Lopes, Eduardo Cararo; Khayati, Khoosheh; Wang, Jianming; Raju, Akash; Rangel, Michael; Lopez, Enrique; Hu, Zhixian Sherrie; Luo, Xuefei; Su, Xiaoyang; Malhotra, Jyoti; Hu, Wenwei; Pine, Sharon R.; White, Eileen; Guo, Jessie Yanxiang 分享 收藏 The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancerLiu, Juan; Zhang, Cen; Xu, Dandan; Zhang, Tianliang; Chang, Chun-Yuan; Wang, Jianming; Liu, Jie; Zhang, Lanjing; Haffty, Bruce G.; Zong, Wei-Xing; Hu, Wenwei; Feng, Zhaohui 分享 收藏 分享 收藏 Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors抑制自噬和MEK促进Lkb1-deficient Kras驱动的肺肿瘤的铁死亡Bhatt, Vrushank; Lan, Taijin; Wang, Wenping; Kong, Jerry; Lopes, Eduardo Cararo; Wang, Jianming; Khayati, Khoosheh; Raju, Akash; Rangel, Michael; Lopez, Enrique; Hu, Zhixian Sherrie; Luo, Xuefei; Su, Xiaoyang; Malhotra, Jyoti; Hu, Wenwei; Pine, Sharon R.; White, Eileen; Guo, Jessie Yanxiang 分享 收藏 Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancerLiu, Juan; Zhang, Cen; Zhang, Tianliang; Chang, Chun-Yuan; Wang, Jianming; Bazile, Ludvinna; Zhang, Lanjing; Haffty, Bruce G. G.; Hu, Wenwei; Feng, Zhaohui 分享 收藏 Sintilimab versus docetaxel as second-line treatment in advanced or metastatic squamous non-small-cell lung cancer: an open-label, randomized controlled phase 3 trial (ORIENT-3)Shi, Yuankai; Wu, Lin; Yu, Xinmin; Xing, Puyuan; Wang, Yan; Zhou, Jianying; Wang, Airong; Shi, Jianhua; Hu, Yi; Wang, Ziping; An, Guangyu; Fang, Yong; Sun, Sanyuan; Zhou, Caicun; Wang, Changli; Ye, Feng; Li, Xingya; Wang, Junye; Wang, Mengzhao; Liu, Yunpeng; Zhao, Yanqiu; Yuan, Ying; Feng, Jifeng; Chen, Zhendong; Shi, Jindong; Sun, Tao; Wu, Gang; Shu, Yongqian; Guo, Qisen; Zhang, Yi; Song, Yong; Zhang, Shucai; Chen, Yuan; Li, Wei; Niu, Hongrui; Hu, Wenwei; Wang, Lijun; Huang, Jianan; Zhang, Yang; Cheng, Ying; Wu, Zhengdong; Peng, Bo; Sun, Jiya; Mancao, Christoph; Wang, Yanqi; Sun, Luyao 分享 收藏 First-line nivolumab plus chemotherapy vs chemotherapy in patients with advanced gastric, gastroesophageal junction and esophageal adenocarcinoma: CheckMate 649 Chinese subgroup analysis晚期胃，胃食管交界处和食管腺癌患者的一线nivolumab加化疗与化疗: CheckMate 649中国亚组分析Liu, Tianshu; Bai, Yuxian; Lin, Xiaoyan; Li, Wei; Wang, Jufeng; Zhang, Xiaochun; Pan, Hongming; Bai, Chunmei; Bai, Li; Cheng, Ying; Zhang, Jingdong; Zhong, Haijun; Ba, Yi; Hu, Wenwei; Xu, Ruihua; Guo, Weijian; Qin, Shukui; Yang, Nong; Lu, Jianwei; Shitara, Kohei; Lei, Ming; Li, Mingshun; Bao, Nicole; Chen, Tian; Shen, Lin 分享 收藏 Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesisYue, Xuetian; Wang, Jianming; Chang, Chun-Yuan; Liu, Juan; Yang, Xue; Zhou, Fan; Qiu, Xia; Bhatt, Vrushank; Guo, Jessie Yanxiang; Su, Xiaoyang; Zhang, Lanjing; Feng, Zhaohui; Hu, Wenwei 分享 收藏 分享 收藏 分享 收藏 Tumor suppressor p53 regulates intestinal type 2 immunityChang, Chun-Yuan; Wang, Jianming; Zhao, Yuhan; Liu, Juan; Yang, Xue; Yue, Xuetian; Wang, Huaying; Zhou, Fan; Inclan-Rico, Juan M.; Ponessa, John J.; Xie, Ping; Zhang, Lanjing; Siracusa, Mark C.; Feng, Zhaohui; Hu, Wenwei 分享 收藏 
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