未登录 Phase Ib study of PRT543, an oral protein arginine methyltransferase 5 (PRMT5) inhibitor, in patients with advanced splicing factor-mutant myeloid malignancies Ib期PRT543研究，PRT543是一种口服蛋白精氨酸甲基转移酶5（PRMT5）抑制剂，用于治疗具有高级别剪接因子突变骨髓性恶性肿瘤的患者 Bewersdorf, Jan Philipp; Mi, Xiaoli; Lu, Bin; Kuykendall, Andrew; Sallman, David; Patel, Manish; Stevens, Don; Philipovskiy, Alexander; Sutamtewagul, Grerk; Masarova, Lucia; Keiffer, Gina; Verma, Amit; Bhagwat, Neha; Wang, Min; Moore, Andrew; Rager, Joseph; Heiser, Diane; Ro, Sunhee; Hong, Wan-Jen; Abdel-Wahab, Omar; Stein, Eytan M. 分享 收藏
Phase Ib Study of PRT543, an Oral Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, in Patients with Relapsed or Refractory, Splicing Factor-Mutant Myeloid Malignancies Ib期研究：PRT543（一种口服蛋白精氨酸甲基转移酶5 [PRMT5] 抑制剂）在复发或难治性、剪接因子突变性髓系恶性肿瘤患者中的应用 Bewersdorf, Jan Philipp; Mi, Xiaoli; Lu, Bin; Kuykendall, Andrew T.; Sallman, David; Patel, Manish; Stevens, Don A.; Philipovskiy, Alexander; Sutamtewagul, Grerk; Masarova, Lucia; Keiffer, Gina; Uerma, Amit; Bhagwat, Neha; Heiser, Diane; Ro, Sunhee; Hong, Wan-Jen; Abdel-Wahab, Omar; Stein, Eytan M. 分享 收藏
分享 收藏
Phase 2 study of venetoclax plus carfilzomib and dexamethasone in patients with relapsed/refractory multiple myeloma Costa, Luciano J.; Davies, Faith E.; Monohan, Gregory P.; Kovacsovics, Tibor; Burwick, Nicholas; Jakubowiak, Andrzej; Kaufman, Jonathan L.; Hong, Wan-Jen; Dail, Monique; Salem, Ahmed Hamed; Yang, Xiaoqing; Masud, Abdullah A.; Munasinghe, Wijith; Ross, Jeremy A.; Bueno, Orlando F.; Kumar, Shaji K.; Stadtmauer, Edward A. 分享 收藏
NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity Richards, Rebecca M.; Zhao, Feifei; Freitas, Katherine A.; Parker, Kevin R.; Xu, Peng; Fan, Amy; Sotillo, Elena; Daugaard, Mads; Oo, Htoo Zarni; Liu, Jie; Hong, Wan-Jen; Sorensen, Poul H.; Chang, Howard Y.; Satpathy, Ansuman T.; Majzner, Robbie G.; Majeti, Ravindra; Mackall, Crystal L. 分享 收藏
Targeting BCL-2 with venetoclax and dexamethasone in patients with relapsed/refractory t(11;14) multiple myeloma Kaufman, Jonathan L.; Gasparetto, Cristina; Schjesvold, Fredrik H.; Moreau, Philippe; Touzeau, Cyrille; Facon, Thierry; Boise, Lawrence H.; Jiang, Yanwen; Yang, Xiaoqing; Dunbar, Fengjiao; Vishwamitra, Deeksha; Unger, Stefanie; Macartney, Tammy; Pesko, John; Yu, Yao; Salem, Ahmed Hamed; Ross, Jeremy A.; Hong, Wan-Jen; Maciag, Paulo C.; Pauff, James M.; Kumar, Shaji 分享 收藏
Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow-up from a phase 1b study Pollyea, Daniel A.; Pratz, Keith; Letai, Anthony; Jonas, Brian A.; Wei, Andrew H.; Pullarkat, Vinod; Konopleva, Marina; Thirman, Michael J.; Arellano, Martha; Becker, Pamela S.; Chyla, Brenda; Hong, Wan-Jen; Jiang, Qi; Potluri, Jalaja; DiNardo, Courtney D. 分享 收藏
Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia 阿扎胞苷和维尼托克在先前未经治疗的急性髓性白血病中的作用 DiNardo, C. D.; Jonas, B. A.; Pullarkat, V.; Thirman, M. J.; Garcia, J. S.; Wei, A. H.; Konopleva, M.; Doehner, H.; Letai, A.; Fenaux, P.; Koller, E.; Havelange, V.; Leber, B.; Esteve, J.; Wang, J.; Pejsa, V.; Hajek, R.; Porkka, K.; Illes, A.; Lavie, D.; Lemoli, R. M.; Yamamoto, K.; Yoon, S. -S.; Jang, J. -H.; Yeh, S. -P.; Turgut, M.; Hong, W. -J.; Zhou, Y.; Potluri, J.; Pratz, K. W. 分享 收藏
Novel and established acute myeloid leukemia (AML) subsets correlate with ex vivo sensitivity to BCL-2 and PI3K inhibition Sumiyoshi, Teiko; Bolen, Chris; Tyner, Jeff; Kurtz, Steve; Borate, Uma; McWeeney, Shannon; Wilmot, Beth; Bottomly, Dan; Segerdell, Erik; Dail, Monique; Wilson, Timothy R.; Hong, Wan-Jen; Venstrom, Jeffrey M. 分享 收藏
分享 收藏
Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation Mazumdar, Claire; Shen, Ying; Xavy, Seethu; Zhao, Feifei; Reinisch, Andreas; Li, Rui; Corces, M. Ryan; Flynn, Ryan A.; Buenrostro, Jason D.; Chan, Steven M.; Thomas, Daniel; Koenig, Julie L.; Hong, Wan-Jen; Chang, Howard Y.; Majeti, Ravindra 分享 收藏
Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia Chan, Steven M.; Thomas, Daniel; Corces-Zimmerman, M. Ryan; Xavy, Seethu; Rastogi, Suchita; Hong, Wan-Jen; Zhao, Feifei; Medeiros, Bruno C.; Tyvoll, David A.; Majeti, Ravindra 分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
