Teresa Fernandes‐Alnemri

Thomas Jefferson University

59H指数

80论文数

2.6W被引数

收录论文 51

发表时间

Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

NATURE COMMUNICATIONS

IF15.7

2021-07-27

OAAI

Mayes-Hopfinger, Lindsey; Enache, Aura; Xie, Jian; Huang, Chou-Long; Kochl, Robert; Tybulewicz, Victor L. J.; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation Gasdermin孔透化线粒体以增强细胞凋亡和炎症小体激活过程中的caspase-3激活

NATURE COMMUNICATIONS

IF15.7

2019-04-11

578

OAAI

Rogers, Corey; Erkes, Dan A.; Nardone, Alexandria; Aplin, Andrew E.; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

SUMO-mediated regulation of NLRP3 modulates inflammasome activity SUMO介导的NLRP3调节炎性体活性

NATURE COMMUNICATIONS

IF15.7

2018-08-01

175

OAAI

Barry, Rachael; John, Sidonie Wicky; Liccardi, Gianmaria; Tenev, Tencho; Jaco, Isabel; Chen, Chih-Hong; Choi, Justin; Kasperkiewicz, Paulina; Fernandes-Alnemri, Teresa; Alnemri, Emad; Drag, Marcin; Chen, Yuan; Meier, Pascal

Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability

CIRCULATION

IF38.6

2018-07-17

OAAI

Paulin, Nicole; Viola, Joana R.; Maas, Sanne L.; de Jong, Renske; Fernandes-Alnemri, Teresa; Weber, Christian; Drechsler, Maik; Doring, Yvonne; Soehnlein, Oliver

Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death 凋亡过程中caspase-3对DFNA5的裂解介导了继发性坏死/热凋亡细胞死亡

NATURE COMMUNICATIONS

IF15.7

2017-01-03

1.1K

OAAI

Rogers, Corey; Fernandes-Alnemri, Teresa; Mayes, Lindsey; Alnemri, Diana; Cingolani, Gino; Alnemri, Emad S.

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 Caspase-8支架功能和MLKL调节TLR3下游的NLRP3炎性体激活

NATURE COMMUNICATIONS

IF15.7

2015-06-24

216

OAAI

Kang, Seokwon; Fernandes-Alnemri, Teresa; Rogers, Corey; Mayes, Lindsey; Wang, Ying; Dillon, Christopher; Roback, Linda; Kaiser, William; Oberst, Andrew; Sagara, Junji; Fitzgerald, Katherine A.; Green, Douglas R.; Zhang, Jianke; Mocarski, Edward S.; Alnemri, Emad S.

Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4

IMMUNOLOGY AND CELL BIOLOGY

IF3

2015-01-20

OAAI

Hwang, Inhwa; Yang, Jungmin; Hong, Sujeong; Lee, Eun Ju; Lee, Seung-Hyo; Fernandes-Alnemri, Teresa; Alnemri, Emad S.; Yu, Je-Wook

A novel role for the mitochondrial HTRA2/OMI protease in aging

AUTOPHAGY

IF14.3

2014-10-27

OAAI

Kang, Seokwon; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function

JOURNAL OF IMMUNOLOGY

IF3.4

2014-04-15

192

OAAI

Ghonime, Mohammed G.; Shamaa, Obada R.; Das, Srabani; Eldomany, Ramadan A.; Fernandes-Alnemri, Teresa; Alnemri, Emad S.; Gavrilin, Mikhail A.; Wewers, Mark D.

The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity

JOURNAL OF IMMUNOLOGY

IF3.4

2013-10-15

223

OAAI

Park, Sangjun; Juliana, Christine; Hong, Sujeong; Datta, Pinaki; Hwang, Inhwa; Fernandes-Alnemri, Teresa; Yu, Je-Wook; Alnemri, Emad S.

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

JOURNAL OF IMMUNOLOGY

IF3.4

2013-10-15

212

OAAI

Fernandes-Alnemri, Teresa; Kang, Seokwon; Anderson, Connor; Sagara, Junji; Fitzgerald, Katherine A.; Alnemri, Emad S.

Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death

CANCER LETTERS

IF10.1

2013-05-01

OAAI

Hong, Sujeong; Hwang, Inhwa; Lee, Yun-Sun; Park, Sangjun; Lee, Won-Keun; Fernandes-Alnemri, Teresa; Alnemri, Emad S.; Kim, You-Sun; Yu, Je-Wook

Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-04-01

OAAI

Yu, Je-Wook; Farias, Andrew; Hwang, Inhwa; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-10-01

682

OAAI

Juliana, Christine; Fernandes-Alnemri, Teresa; Kang, Seokwon; Farias, Andrew; Qin, Fengsong; Alnemri, Emad S.

Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging 成年小鼠非神经元组织中HtrA2/Omi活性的丧失会导致过早衰老

CELL DEATH AND DIFFERENTIATION

IF15.4

2012-09-14

OAAI

Kang, S.; Louboutin, J-P; Datta, P.; Landel, C. P.; Martinez, D.; Zervos, A. S.; Strayer, D. S.; Fernandes-Alnemri, T.; Alnemri, E. S.

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection

JOURNAL OF IMMUNOLOGY

IF3.4

2011-11-01

151

OAAI

Fang, Rendong; Tsuchiya, Kohsuke; Kawamura, Ikuo; Shen, Yanna; Hara, Hideki; Sakai, Shunsuke; Yamamoto, Takeshi; Fernandes-Alnemri, Teresa; Yang, Ruili; Hernandez-Cuellar, Eduardo; Dewamitta, Sita R.; Xu, Yanting; Qu, Huixin; Alnemri, Emad S.; Mitsuyama, Masao

Cutting Edge: Mutation of Francisella tularensis mviN Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence

JOURNAL OF IMMUNOLOGY

IF3.4

2010-09-01

OAAI

Ulland, Tyler K.; Buchan, Blake W.; Ketterer, Margaret R.; Fernandes-Alnemri, Teresa; Meyerholz, David K.; Apicella, Michael A.; Alnemri, Emad S.; Jones, Bradley D.; Nauseef, William M.; Sutterwala, Fayyaz S.

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes AIM2，NLRC4和NLRP3炎性小体参与单核细胞增生李斯特菌的Caspase-1激活

JOURNAL OF CLINICAL IMMUNOLOGY

IF5.7

2010-05-20

262

OAAI

Wu, Jianghong; Fernandes-Alnemri, Teresa; Alnemri, Emad S.

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis AIM2炎症小体对于土拉弗朗西斯菌的先天免疫至关重要

NATURE IMMUNOLOGY

IF27.6

2010-03-28

672

OAAI

Fernandes-Alnemri, Teresa; Yu, Je-Wook; Juliana, Christine; Solorzano, Leobaldo; Kang, Seokwon; Wu, Jianghong; Datta, Pinaki; McCormick, Margaret; Huang, Lan; McDermott, Erin; Eisenlohr, Laurence; Landel, Carlisle P.; Alnemri, Emad S.

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-03-01

565

OAAI

Juliana, Christine; Fernandes-Alnemri, Teresa; Wu, Jianghong; Datta, Pinaki; Solorzano, Leobaldo; Yu, Je-Wook; Meng, Rong; Quong, Andrew A.; Latz, Eicke; Scott, Charles P.; Alnemri, Emad S.

研究方向