Christopher J. Earley - Publications, H-index & Citations

Christopher J. Earley

Johns Hopkins University

76H指数

247论文数

2.0W被引数

收录论文 144

发表时间

Dopaminergic hypersensitivity of the opioid-responsive striatal–entopeduncular pathway in a rodent model of restless legs syndrome 阿片反应性纹状体-内囊束通路的多巴胺能高敏感性：来自不安腿综合征啮齿动物模型的研究

Neuropsychopharmacology

IF7.1

2026-04-17

OAAI

Marta Valle-León; William Rea; César Quiroz; William N. Sánchez; Sandra Albornoz; Ana M. Rule; Ning-Sheng Cai; Francisco Ciruela; Christopher J. Earley; Sergi Ferré

Locomotor activity depends on β-arrestin recruitment by the dopamine D1 receptor in the striatal D1-D3 receptor heteromer 运动活动依赖于纹状体D1-D3受体异聚体中多巴胺D1受体对β-抑制蛋白的募集。

Pharmacological Research

IF10.5

2025-06-14

OAAI

Alexandra H. Evans; Marc Ciruela-Jardí; William Rea; Bradley M. Keegan; Marjorie R. Levinstein; Alessandro Bonifazi; Jianjing Cao; Shelley N. Jackson; Lei Shi; Nil Casajuana-Martin; Ning-Sheng Cai; Vicent Casadó; Christopher J. Earley; Amy H. Newman; Michael Michaelides; Leonardo Pardo; Estefanía Moreno; Sergi Ferré

Rethinking clinical trials in restless legs syndrome: A roadmap

SLEEP MEDICINE REVIEWS

IF9.7

2024-10-01

PREAI

Garcia-Borreguero, Diego; Black, Jed; Earley, Christopher J.; Fulda, Stephany; Hoegl, Birgit; Manconi, Mauro; Ondo, William; Roth, Thomas; Trenkwalder, Claudia; Winkelman, John W.

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction 不宁腿综合征的全基因组荟萃分析可深入了解遗传结构，疾病生物学和风险预测

NATURE GENETICS

IF31.8

2024-06-05

OAAI

Schormair, Barbara; Zhao, Chen; Bell, Steven; Didriksen, Maria; Nawaz, Muhammad S.; Schandra, Nathalie; Stefani, Ambra; Hoegl, Birgit; Dauvilliers, Yves; Bachmann, Cornelius G.; Kemlink, David; Sonka, Karel; Paulus, Walter; Trenkwalder, Claudia; Oertel, Wolfgang H.; Hornyak, Magdolna; Teder-Laving, Maris; Metspalu, Andres; Hadjigeorgiou, Georgios M.; Polo, Olli; Fietze, Ingo; Ross, Owen A.; Wszolek, Zbigniew K.; Ibrahim, Abubaker; Bergmann, Melanie; Kittke, Volker; Harrer, Philip; Dowsett, Joseph; Chenini, Sofiene; Ostrowski, Sisse Rye; Sorensen, Erik; Erikstrup, Christian; Pedersen, Ole B.; Bruun, Mie Topholm; Nielsen, Kaspar R.; Butterworth, Adam S.; Soranzo, Nicole; Ouwehand, Willem H.; Roberts, David J.; Danesh, John; Burchell, Brendan; Furlotte, Nicholas A.; Nandakumar, Priyanka; Earley, Christopher J.; Ondo, William G.; Xiong, Lan; Desautels, Alex; Perola, Markus; Vodicka, Pavel; Dina, Christian; Stoll, Monika; Franke, Andre; Lieb, Wolfgang; Stewart, Alexandre F. R.; Shah, Svati H.; Gieger, Christian; Peters, Annette; Rye, David B.; Rouleau, Guy A.; Berger, Klaus; Stefansson, Hreinn; Ullum, Henrik; Stefansson, Kari; Hinds, David A.; Di Angelantonio, Emanuele; Oexle, Konrad; Winkelmann, Juliane

Brain Iron Dysregulation in Iron Deficiency Anemia-Related Restless Leg Syndrome Revealed by Neuron-Derived Extracellular Vesicles: A Case-Control Study

ANNALS OF NEUROLOGY

IF7.7

2024-04-22

OAAI

Manolopoulos, Apostolos; York, William; Pucha, Krishna Ananthu; Earley, Christopher J.; Kapogiannis, Dimitrios

Clinical efficacy and safety of intravenous ferric carboxymaltose for treatment of restless legs syndrome: a multicenter, randomized, placebo-controlled clinical trial 静脉注射铁羧基麦芽糖治疗不宁腿综合征的临床疗效和安全性: 一项多中心，随机，安慰剂对照的临床试验

SLEEP

IF4.9

2024-04-16

PREAI

Earley, Christopher J.; Garcia-Borreguero, Diego; Falone, Mark; Winkelman, John W.

A randomized double-blind pilot study to evaluate the efficacy, safety, and tolerability of intravenous iron versus oral iron for the treatment of restless legs syndrome in patients with iron deficiency anemia

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2024-03-13

PREAI

Short, Vanessa; Allen, Richard; Earley, Christopher J.; Bahrain, Huzefa; Rineer, Stella; Kashi, Kiumarce; Gerb, Jesse; Auerbach, Michael

On the optimization of 3D inflow-based vascular-space-occupancy (iVASO) MRI for the quantification of arterial cerebral blood volume (CBVa)

MAGNETIC RESONANCE IN MEDICINE

IF3

2023-12-19

PREAI

Gu, Chunming; Li, Yinghao; Cao, Di; Miao, Xinyuan; Paez, Adrian G.; Sun, Yuanqi; Cai, Jitong; Li, Wenbo; Li, Xu; Pillai, Jay J.; Earley, Christopher J.; van Zijl, Peter C. M.; Hua, Jun

Restless legs syndrome, neuroleptic-induced akathisia, and opioid-withdrawal restlessness: shared neuronal mechanisms?不宁腿综合征，精神安定药引起的静坐症和阿片类药物戒断躁动: 共同的神经元机制？

SLEEP

IF4.9

2023-10-21

OAAI

Ferre, Sergi; Winkelman, John; Garcia-Borreguero, Diego; Belcher, Annabelle; Chang, Joy; Earley, Christopher

Ferric carboxymaltose effects on restless legs syndrome and on brain iron in patients with iron deficiency anemia

SLEEP MEDICINE

IF3.4

2023-09-01

OAAI

Bae, Hyoeun; Cho, Yong Won; Kim, Keun Tae; Li, Xu; Earley, Christopher J.

Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants 多巴胺D4受体及其多态性变体的功能和药理作用

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2022-09-30

OAAI

Ferre, Sergi; Belcher, Annabelle M.; Bonaventura, Jordi; Quiroz, Cesar; Sanchez-Soto, Marta; Casado-Anguera, Veronica; Cai, Ning-Sheng; Moreno, Estefania; Boateng, Comfort A.; Keck, Thomas M.; Floran, Benjamin; Earley, Christopher J.; Ciruela, Francisco; Casado, Vicent; Rubinstein, Marcelo; Volkow, Nora D.

A pilot study to understand the relationship between cortical arousals and leg movements during sleep

SCIENTIFIC REPORTS

IF3.9

2022-07-25

OAAI

Bansal, Kanika; Garcia, Javier; Feltch, Cody; Earley, Christopher; Robucci, Ryan; Banerjee, Nilanjan; Brooks, Justin

Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs Syndrome 脑铁缺乏改变皮质-纹状体末梢腺苷受体亚型的化学计量: 对不宁腿综合征的影响

MOLECULES

IF4.6

2022-02-23

OAAI

Rodrigues, Matilde S.; Ferreira, Samira G.; Quiroz, Cesar; Earley, Christopher J.; Garcia-Borreguero, Diego; Cunha, Rodrigo A.; Ciruela, Francisco; Kofalvi, Attila; Ferre, Sergi

Randomized, placebo-controlled trial of ferric carboxymaltose in restless legs syndrome patients with iron deficiency anemia

SLEEP MEDICINE

IF3.4

2021-08-01

PREAI

Bae, Hyoeun; Cho, Yong Won; Kim, Keun Tae; Allen, Richard P.; Earley, Christopher J.

We need to do better: A systematic review and meta-analysis of diagnostic test accuracy of restless legs syndrome screening instruments

SLEEP MEDICINE REVIEWS

IF9.7

2021-08-01

PREAI

Fulda, Stephany; Allen, Richard P.; Earley, Christopher J.; Hogl, Birgit; Garcia-Borreguero, Diego; Inoue, Yuichi; Ondo, William; Walters, Arthur S.; Williams, Anne-Marie; Winkelman, John W.

The Management of Restless Legs Syndrome: An Updated Algorithm

MAYO CLINIC PROCEEDINGS

IF6.7

2021-07-01

OAAI

Silber, Michael H.; Buchfuhrer, Mark J.; Earley, Christopher J.; Koo, Brian B.; Manconi, Mauro; Winkelman, John W.

Akathisia and Restless Legs Syndrome Solving the Dopaminergic Paradox 静坐症和不宁腿综合征解决了多巴胺能悖论

SLEEP MEDICINE CLINICS

IF4.9

2021-06-01

PREAI

Ferre, Sergi; Guitart, Xavier; Quiroz, Cesar; Rea, William; Garcia-Malo, Celia; Garcia-Borreguero, Diego; Allen, Richard P.; Earley, Christopher J.