未登录 Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity 人巨细胞病毒感染劫持染色质组织以减弱TEAD1转录因子活性 Sayeed, Khund; Parameswaran, Sreeja; Beucler, Matthew J.; Edsall, Lee E.; VonHandorf, Andrew; Crowther, Audrey; Donmez, Omer A.; Hass, Matthew R.; Richards, Scott; Forney, Carmy R.; Hesse, Hayley K.; Jones, Sydney H.; Dunn, Katelyn A.; Wright, Jay; Leong, Merrin Man Long; Murray-Nerger, Laura A.; Yechoor, Vijay; Gewurz, Ben E.; Kaufman, Kenneth M.; Harley, John B.; Zhao, Bo; Miller, William E.; Kottyan, Leah C.; Weirauch, Matthew T. 分享 收藏
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Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome Viel, Kenyatta C. M. F.; Parameswaran, Sreeja; Donmez, Omer A.; Forney, Carmy R.; Hass, Matthew R.; Yin, Cailing; Jones, Sydney H.; Prosser, Hayley K.; Diouf, Arame A.; Gittens, Olivia E.; Edsall, Lee E.; Chen, Xiaoting; Rowden, Hope; Dunn, Katelyn A.; Guo, Rui; Vonhandorf, Andrew; Leong, Merrin Man Long; Ernst, Kevin; Kaufman, Kenneth M.; Lawson, Lucinda P.; Gewurz, Ben; Zhao, Bo; Kottyan, Leah C.; Weirauch, Matthew T. 分享 收藏
The US Department of Veterans Affairs Science and Health Initiative to Combat Infectious and Emerging Life-Threatening Diseases (VA SHIELD): A Biorepository Addressing National Health Threats Harley, John B.; Pyarajan, Saiju; Partan, Elizabeth S.; Epstein, Lauren; Wertheim, Jason A.; Diwan, Abhinav; Woods, Christopher W.; Davey, Victoria; Blair, Sharlene; Clark, Dennis H.; Kaufman, Kenneth M.; Khan, Shagufta; Chepelev, Iouri; Devine, Alexander; Cameron, Perry; McCann, Monica F.; Ammons, Mary Cloud B.; Bolz, Devin D.; Battles, Jane K.; Curtis, Jeffrey L.; Holodniy, Mark; Marconi, Vincent C.; Searles, Charles D.; Beenhouwer, David O.; Brown, Sheldon T.; Moorman, Jonathan P.; Yao, Zhi Q.; Rodriguez-Barradas, Maria C.; Mohapatra, Shyam; De Rodriguez, Osmara Y. Molina; Padiernos, Emerson B.; McIndoo, Eric R.; Price, Emily; Burgoyne, Hailey M.; Robey, Ian; Schwenke, Dawn C.; Shive, Carey L.; Przygodzki, Ronald M.; Ramoni, Rachel B.; Krull, Holly K.; Bonomo, Robert A. 分享 收藏
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations 遗传多样性人群冠状动脉疾病的大规模全基因组关联研究 Tcheandjieu, Catherine; Zhu, Xiang; Hilliard, Austin T.; Clarke, Shoa L.; Napolioni, Valerio; Ma, Shining; Lee, Kyung Min; Fang, Huaying; Chen, Fei; Lu, Yingchang; Tsao, Noah L.; Raghavan, Sridharan; Koyama, Satoshi; Gorman, Bryan R.; Vujkovic, Marijana; Klarin, Derek; Levin, Michael G.; Sinnott-Armstrong, Nasa; Wojcik, Genevieve L.; Plomondon, Mary E.; Maddox, Thomas M.; Waldo, Stephen W.; Bick, Alexander G.; Pyarajan, Saiju; Huang, Jie; Song, Rebecca; Ho, Yuk-Lam; Buyske, Steven; Kooperberg, Charles; Haessler, Jeffrey; Loos, Ruth J. F.; Do, Ron; Verbanck, Marie; Chaudhary, Kumardeep; North, Kari E.; Avery, Christy L.; Graff, Mariaelisa; Haiman, Christopher A.; Le Marchand, Loic; Wilkens, Lynne R.; Bis, Joshua C.; Leonard, Hampton; Shen, Botong; Lange, Leslie A.; Giri, Ayush; Dikilitas, Ozan; Kullo, Iftikhar J.; Stanaway, Ian B.; Jarvik, Gail P.; Gordon, Adam S.; Hebbring, Scott; Namjou, Bahram; Kaufman, Kenneth M.; Ito, Kaoru; Ishigaki, Kazuyoshi; Kamatani, Yoichiro; Verma, Shefali S.; Ritchie, Marylyn D.; Kember, Rachel L.; Baras, Aris; Lotta, Luca A.; Kathiresan, Sekar; Hauser, Elizabeth R.; Miller, Donald R.; Lee, Jennifer S.; Saleheen, Danish; Reaven, Peter D.; Cho, Kelly; Gaziano, J. Michael; Natarajan, Pradeep; Huffman, Jennifer E.; Voight, Benjamin F.; Rader, Daniel J.; Chang, Kyong-Mi; Lynch, Julie A.; Damrauer, Scott M.; Wilson, Peter W. F.; Tang, Hua; Sun, Yan, V; Tsao, Philip S.; O'Donnell, Christopher J.; Assimes, Themistocles L. 分享 收藏
Epigenetic and transcriptional dysregulation in CD4+T cells in patients with atopic dermatitis Eapen, Amy A.; Parameswaran, Sreeja; Forney, Carmy; Edsall, Lee E.; Miller, Daniel; Donmez, Omer; Dunn, Katelyn; Lu, Xiaoming; Granitto, Marissa; Rowden, Hope; Magier, Adam Z.; Pujato, Mario; Chen, Xiaoting; Kaufman, Kenneth; Bernstein, David, I; Devonshire, Ashley L.; Rothenberg, Marc E.; Weirauch, Matthew T.; Kottyan, Leah C. 分享 收藏
Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery 狼疮增强子风险变异通过协同lncRNA和DNA甲基化机制导致IRF8失调 Zhou, Tian; Zhu, Xinyi; Ye, Zhizhong; Wang, Yong-Fei; Yao, Chao; Xu, Ning; Zhou, Mi; Ma, Jianyang; Qin, Yuting; Shen, Yiwei; Tang, Yuanjia; Yin, Zhihua; Xu, Hong; Zhang, Yutong; Zang, Xiaoli; Ding, Huihua; Yang, Wanling; Guo, Ya; Harley, John B.; Namjou, Bahram; Kaufman, Kenneth M.; Kottyan, Leah C.; Weirauch, Matthew T.; Hou, Guojun; Shen, Nan 分享 收藏
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Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis Shoda, Tetsuo; Kaufman, Kenneth M.; Wen, Ting; Caldwell, Julie M.; Osswald, Garrett A.; Purnima, Pathre; Zimmermann, Nives; Collins, Margaret H.; Rehn, Kira; Foote, Heather; Eby, Michael D.; Zhang, Wenying; Morgenstern, Netali Ben-Baruch; Ballaban, Adina Y.; Habel, Jeff E.; Kottyan, Leah C.; Abonia, J. Pablo; Mukkada, Vincent A.; Putnam, Philip E.; Martin, Lisa J.; Rothenberg, Marc E. 分享 收藏
Validation of low-coverage whole-genome sequencing for mitochondrial DNA variants suggests mitochondrial DNA as a genetic cause of preterm birth 线粒体DNA变异的低覆盖率全基因组测序验证表明线粒体DNA是早产的遗传原因 Yang, Zeyu; Slone, Jesse; Wang, Xinjian; Zhan, Jack; Huang, Yongbo; Namjou, Bahram; Kaufman, Kenneth M.; Pauciulo, Michael; Harley, John B.; Muglia, Louis J.; Chepelev, Iouri; Huang, Taosheng 分享 收藏
Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis 类风湿性关节炎遗传易感性的多效性: 一项全表型关联研究和逆方差加权Meta分析 Kawai, Vivian K.; Shi, Mingjian; Feng, Qiping; Chung, Cecilia P.; Liu, Ge; Cox, Nancy J.; Jarvik, Gail P.; Lee, Ming T. M.; Hebbring, Scott J.; Harley, John B.; Kaufman, Kenneth M.; Namjou, Bahram; Larson, Eric; Gordon, Adam S.; Roden, Dan M.; Stein, C. Michael; Mosley, Jonathan D. 分享 收藏
Complete Tracheal Ring Deformity A Translational Genomics Approach to Pathogenesis Sinner, Debora I.; Carey, Brenna; Zgherea, Daniela; Kaufman, K. M.; Leesman, Lauren; Wood, Robert E.; Rutter, Michael J.; de Alarcon, Alessandro; Elluru, Ravindhra G.; Harley, John B.; Whitsett, Jeffrey A.; Trapnell, Bruce C. 分享 收藏
Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma Bernstein, David I.; Lummus, Zana L.; Kesavalu, Banu; Yao, Jianbo; Kottyan, Leah; Miller, Daniel; Cartier, Andre; Cruz, Maria-Jesus; Lemiere, Catherine; Munoz, Xavier; Quirce, Santiago; Tarlo, Susan; Sastre, Joaquin; Boulet, Louis Philippe; Weirauch, Matthew T.; Kaufman, Kenneth 分享 收藏
Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans Hanscombe, Ken B.; Morris, David L.; Noble, Janelle A.; Dilthey, Alexander T.; Tombleson, Philip; Kaufman, Kenneth M.; Comeau, Mary; Langefeld, Carl D.; Alarcon-Riquelme, Marta E.; Gaffney, Patrick M.; Jacob, Chaim O.; Sivils, Kathy L.; Tsao, Betty P.; Alarcon, Graciela S.; Brown, Elizabeth E.; Croker, Jennifer; Edberg, Jeff; Gilkeson, Gary; James, Judith A.; Kamen, Diane L.; Kelly, Jennifer A.; McCune, Joseph; Merri, Joan T.; Petri, Michelle; Ramsey-Goldman, Rosalind; Reveille, John D.; Salmon, Jane E.; Scofield, Hal; Utset, Tammy; Wallace, Daniel J.; Weisman, Michael H.; Kimberly, Robert P.; Harley, John B.; Lewis, Cathryn M.; Criswell, Lindsey A.; Vyse, Timothy J. 分享 收藏
Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis Kottyan, Leah C.; Maddox, Avery; Braxton, Julian R.; Stucke, Emily M.; Mukkada, Vince; Putnam, Philip E.; Abonia, J. Pablo; Chehade, Mirna; Wood, Robert A.; Pesek, Robbie D.; Vickery, Brian P.; Furuta, Glenn T.; Dawson, Peter; Sampson, Hugh A.; Martin, Lisa J.; Kelly, Jennifer A.; Kimberly, Robert P.; Sivils, Kathy; Gaffney, Patrick M.; Kaufman, Kenneth; Harley, John B.; Rothenberg, Marc E. 分享 收藏
Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis Sherrill, Joseph D.; Kiran, K. C.; Wang, Xinjian; Wen, Ting; Chamberlin, Adam; Stucke, Emily M.; Collins, Margaret H.; Abonia, J. Pablo; Peng, Yanyan; Wu, Qiang; Putnam, Philip E.; Dexheimer, Phillip J.; Aronow, Bruce J.; Kottyan, Leah C.; Kaufman, Kenneth M.; Harley, John B.; Huang, Taosheng; Rothenberg, Marc E. 分享 收藏
A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus STAT1-STAT4基因座中可能具有因果关系的功能性狼疮相关风险变体 Patel, Zubin H.; Lu, Xiaoming; Miller, Daniel; Forney, Carmy R.; Lee, Joshua; Lynch, Arthur; Schroeder, Connor; Parks, Lois; Magnusen, Albert F.; Chen, Xiaoting; Pujato, Mario; Maddox, Avery; Zoller, Erin E.; Namjou, Bahram; Brunner, Hermine, I; Henrickson, Michael; Huggins, Jennifer L.; Williams, Adrienne H.; Ziegler, Julie T.; Comeau, Mary E.; Marion, Miranda C.; Glenn, Stuart B.; Adler, Adam; Shen, Nan; Nath, Swapan K.; Stevens, Anne M.; Freedman, Barry, I; Pons-Estel, Bernardo A.; Tsao, Betty P.; Jacob, Chaim O.; Kamen, Diane L.; Brown, Elizabeth E.; Gilkeson, Gary S.; Alarcon, Graciela S.; Martin, Javier; Reveille, John D.; Anaya, Juan-Manuel; James, Judith A.; Sivils, Kathy L.; Criswell, Lindsey A.; Vila, Luis M.; Petri, Michelle; Scofield, R. Hal; Kimberly, Robert P.; Edberg, Jeffrey C.; Ramsey-Goldman, Rosalind; Bang, So-Young; Lee, Hye-Soon; Bae, Sang-Cheol; Boackle, Susan A.; Graham, Deborah Cunninghame; Vyse, Timothy J.; Merrill, Joan T.; Niewold, Timothy B.; Ainsworth, Hannah C.; Silverman, Earl D.; Weisman, Michael H.; Wallace, Daniel J.; Raj, Prithvi; Guthridge, Joel M.; Gaffney, Patrick M.; Kelly, Jennifer A.; Alarcon-Riquelme, Marta E.; Langefeld, Carl D.; Wakeland, Edward K.; Kaufman, Kenneth M.; Weirauch, Matthew T.; Harley, John B.; Kottyan, Leah C. 分享 收藏
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity Harley, John B.; Chen, Xiaoting; Pujato, Mario; Miller, Daniel; Maddox, Avery; Forney, Carmy; Magnusen, Albert F.; Lynch, Arthur; Chetal, Kashish; Yukawa, Masashi; Barski, Artem; Salomonis, Nathan; Kaufman, Kenneth M.; Kottyan, Leah C.; Weirauch, Matthew T. 分享 收藏
Regulatory Variants of ATF3, CDH17 and FAM71A are Risk Factors for Diisocyanate Induced Occupational Asthma (DA) Lummus, Zana L.; Kesavalu, Banu; Kaufman, Kenneth; Yao, Jianbo; Weirauch, Matthew T.; Kottyan, Leah C.; Miller, Daniel; Cartier, Andre; Cruz, Maria-Jesus; Lemiere, Catherine; Munoz, Xavier; Quirce, Santiago; Sastre, Joaquin; Tarlo, Susan M.; Bernstein, David I. 分享 收藏
X chromosomal linkage to eosinophilic esophagitis susceptibility Kottyan, Leah C.; Maddox, Avery; Hoffman, Kate; Ray, Leanne; Forney, Carmey; Eby, Michael; Mingler, Melissa K.; Kaufman, Kenneth; Dexheimer, Phillip; Lukac, Nina; Caldwell, Julie M.; Rochman, Mark; Shoda, Tetsuo; Wen, Ting; Wheeler, Justin C.; Hogan, Simon P.; Mukkada, Vincent A.; Putnam, Philip E.; Abonia, Pablo P.; Genta, Robert M.; Martin, Lisa J.; Dellon, Evan S.; Rothenberg, Marc E. 分享 收藏
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