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Steven J. Isakoff

mass general brig ham cancer institute

60H指数
449论文数
2.6W被引数
收录论文 138
发表时间
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Metastatic metaplastic triple negative breast cancer response to sacituzumab govitecan and biomarker targetability转移性化生性三阴性乳腺癌对沙库巴曲珠单抗的应答及生物标志物靶向性
errBreast Cancer Research and Treatment
IF3
err2026-09-30
err0
PREAI
errShivahamy Maheswaran; Aylin S. Dedeoglu; Andrzej Niemierko; Rachel O. Abelman; Rachel Jimenez; Olivia Rieur; Jennifer Hutchinson; Neelima Vidula; Laura M. Spring; Leif W. Ellisen; Steven J. Isakoff; Seth A. Wander; Aditya Bardia; Arielle J. Medford
err分享
err收藏
Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer来自12,827例转移性乳腺癌患者循环DNA中可操作的遗传景观和动态
errNature Communications
IF15.7
err2026-09-22
err0
errOAAI
errIgnaty Leshchiner; Arielle J. Medford; Justin Cha; Lesli A. Kiedrowski; Andrzej Niemierko; Jennifer C. Keenan; Charles S. Dai; Laura M. Spring; Beverly Moy; Seth A. Wander; Neelima Vidula; Steven J. Isakoff; Dejan Juric; Mendy Miller; Andrew A. Davis; Lorenzo Gerratana; Ami Shah; Ben H. Park; Adam Brufsky; Joyce O’Shaughnessy; Rebecca J. Nagy; Leif W. Ellisen; Massimo Cristofanilli; Aditya Bardia; Gad Getz
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err收藏
Safety and antitumour activity of ipatasertib combined with endocrine therapy and a CDK4/6 inhibitor in HR+/HER2– metastatic breast cancer (TAKTIC): a single-centre, open-label, phase 1b trial伊帕西替布联合内分泌疗法和CDK4/6抑制剂在HR+/HER2–转移性乳腺癌中的安全性和抗肿瘤活性（TAKTIC）：一项单中心、开放标签、1b期临床试验
errThe Lancet Oncology
IF0
err2026-04-27
err0
PREAI
errSeth A Wander; Maxwell R Lloyd; Jennifer C Keenan; Elizabeth C Scott; Andrzej Niemierko; Laura M Spring; Geoffrey G Fell; Jennifer Shin; Steven J Isakoff; Beverly Moy; Lianne Ryan; Sarah Padden; Elizabeth Fisher; Amber Newton; Karleen R Habin; Elene T Viscosi-Spieler; Lauren Scarpetti; Andreas Varkaris; Leif W Ellisen; Taronish Dubash
err分享
err收藏
A TROP2/Claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errWu, Bogang; Thant, Win; Bitman, Elena; Liu, Ting; Liu, Jie; Ilios, Eleftherios Paschalis; Xu, Katherine; Nieman, Linda; Ting, David; Thimmiah, Nayana; Sun, Sheng; Abelman, Rachel; Isakoff, Steven; Spring, Laura; Bardia, Aditya; Ellisen, Leif
err分享
err收藏
Leveraging real-world evidence to personalize adjuvant therapy in HR+/HER2- early breast cancer利用真实世界证据个性化HR+/HER2-早期乳腺癌的辅助治疗
errJNCI CANCER SPECTRUM
IF4.1
err2025-10-01
err0
PREAI
errBar, Yael; Isakoff, Steven J.; Wander, Seth A.
err分享
err收藏
Selection biases in the systematic collection of breast biobank specimens系统化收集乳腺生物样本库标本时的选择偏倚
errnpj Breast Cancer
IF7.6
err2025-08-01
err0
errOAAI
errYael Bar; Gary X. Wang; Gabrielle E. Gioia; Geoffrey Fell; Shinn-Huey S. Chou; Veerle Bossuyt; Steven J. Isakoff; Beverly Moy; Leif W. Ellisen; Constance D. Lehman; Laura M. Spring
err分享
err收藏
Dynamic HER2-low status among patients with triple negative breast cancer (TNBC) and the impact of repeat biopsies三阴性乳腺癌（TNBC）患者中动态HER2-low状态及重复活检的影响
errNPJ BREAST CANCER
IF7.6
err2025-03-11
err0
errOAAI
errBar, Yael; Fell, Geoffrey; Dedeoglu, Aylin; Moffett, Natalie; Vidula, Neelima; Spring, Laura; Wander, Seth A.; Bardia, Aditya; Ko, Naomi; Moy, Beverly; Ellisen, Leif W.; Isakoff, Steven J.
err分享
err收藏
Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2- breast cancer (LEADER)
errNPJ BREAST CANCER
IF7.6
err2025-01-07
err0
errOAAI
errSpring, Laura M.; Scarpetti, Lauren; Medford, Arielle J.; Niemierko, Andrzej; Comander, Amy; Mulvey, Therese; Schnipper, Lowell; Isakoff, Steven J.; Moy, Beverly; Wander, Seth A.; Shin, Jennifer; Ephrem, Zanta; Laposta, Anneke R.; Denault, Elyssa; Abraham, Elizabeth; Calistro, Gayle; Kalashnikova, Ekaterina; Rodriguez, Angel; Liu, Minetta C.; Aleshin, Alexey; Peppercorn, Jeffrey; Ellisen, Leif W.; Bardia, Aditya
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A prospective study of HER3 expression pre and post neoadjuvant therapy of different breast cancer subtypes: implications for HER3 imaging therapy guidance不同乳腺癌亚型新辅助治疗前后HER3表达的前瞻性研究: 对HER3影像学治疗指导的意义
errBREAST CANCER RESEARCH
IF5.6
err2024-06-29
err1
errOAAI
errSinevici, Nicoleta; Edmonds, Christine E.; Dontchos, Brian N.; Wang, Gary; Lehman, Constance D.; Isakoff, Steven; Mahmood, Umar
err分享
err收藏
Functional hemodynamic imaging markers for the prediction of pathological outcomes in breast cancer patients treated with neoadjuvant chemotherapy
errJOURNAL OF BIOMEDICAL OPTICS
IF2.9
err2024-05-11
err0
errOAAI
errDeng, Bin; Muldoon, Ailis; Cormier, Jayne; Mercaldo, Nathaniel D.; Niehoff, Elizabeth; Moffett, Natalie; Saksena, Mansi A.; Isakoff, Steven J.; Carp, Stefan A.
err分享
err收藏
Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errVarkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth; Nordern, Bryanna; Chevalier, Nicholas; Leshchiner, Ignaty; Stavridi, Anastasia; Kim, Janice; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg; Bardia, Aditya; Spring, Laura; Isakoff, Steven; Lennerz, Jochen; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan; Juric, Dejan
err分享
err收藏
Sequencing Antibody-Drug Conjugate after Antibody-Drug Conjugate in Metastatic Breast Cancer (A3 study): Multi-Institution Experience and Biomarker Analysis
errCANCER RESEARCH
IF16.6
err2024-05-02
err4
PREAI
errAbelman, Rachel Occhiogrosso; Spring, Laura; Fell, Geoffrey; Davis, Andrew; Hensing, Whitney; Ryan, Phoebe; Vidula, Neelima; Wander, Seth; Medford, Arielle; Shin, Jennifer; Abraham, Elizabeth; Isakoff, Steven; Moy, Beverly; Ellisen, Leif; Bardia, Aditya
err分享
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Personalized ctDNA testing for detection of molecular residual disease in patients with localized HR plus breast cancer: temporal dynamics and impact on clinical outcomes
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errMedford, Arielle; Denault, Elyssa; Ephrem, Zanta; Micalizzi, Douglas; Bar, Yael; Abelman, Rachel; Comander, Amy; Knape, Justine; Liu, Minetta; Rodriguez, Angel; Isakoff, Steven; Moy, Beverly; Spring, Laura; Bardia, Aditya
err分享
err收藏
A first-inhuman study of the highly selective PI3Ka inhibitor RLY-5836 in patients with advanced breast cancer and other solid tumors
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errVarkaris, Andreas; Isakoff, Steven; Perez, Cesar A.; O'Neil, Bert; Hamilton, Erika; Conlin, Erin; Tan, Gege; Li, Xiaoyan; Timm, Alison; Samadani, Ramin; Puente-Poushnejad, Erika; Kwak, Eunice; Mar, Brenton G.; Schram, Alison M.
err分享
err收藏
Genomic spectrum of actionable alterations in serial cell free DNA (cfDNA) analysis of patients with metastatic breast cancer
errNPJ BREAST CANCER
IF7.6
err2024-04-11
err1
errOAAI
errBar, Yael; Keenan, Jennifer C.; Niemierko, Andrzej; Medford, Arielle J.; Isakoff, Steven J.; Ellisen, Leif W.; Bardia, Aditya; Vidula, Neelima
err分享
err收藏
Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errde la Cruz, Ferran Fece; Varkaris, Andreas; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Patel, Parasvi; Kim, Janice S.; Ellis, Haley; Sanidas, Ioannis; Lau, Kayao T.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan
err分享
err收藏
Response-guided neoadjuvant sacituzumab govitecan for localized triple-negative breast cancer: results from the NeoSTAR trialsacituzumab govitecan治疗局部三阴性乳腺癌的新辅助治疗: 来自NeoSTAR试验的结果
errANNALS OF ONCOLOGY
IF65.4
err2024-03-01
err13
errOAAI
errSpring, L. M.; Tolaney, S. M.; Fell, G.; Bossuyt, V.; Abelman, R. O.; Wu, B.; Maheswaran, S.; Trippa, L.; Comander, A.; Mulvey, T.; McLaughlin, S.; Ryan, P.; Ryan, L.; Abraham, E.; Rosenstock, A.; Garrido-Castro, A. C.; Lynce, F.; Moy, B.; Isakoff, S. J.; Tung, N.; Mittendorf, E. A.; Ellisen, L. W.; Bardia, A.
err分享
err收藏
Searching for the Holy Grail of breast cancer recurrence risk: a narrative review of the hunt for a better biomarker and the promise of circulating tumor DNA (ctDNA)寻找乳腺癌复发风险的圣杯: 寻找更好的生物标志物和循环肿瘤DNA (ctDNA) 的前景的叙述性回顾
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-02-15
err5
PREAI
errGao, Lucy; Medford, Arielle; Spring, Laura; Bar, Yael; Hu, Bonnie; Jimenez, Rachel; Isakoff, Steven J.; Bardia, Aditya; Peppercorn, Jeffrey
err分享
err收藏
Intratumoral heterogeneity drives resistance to Antibody Drug Conjugate therapy: Analysis of the NeoSTAR trial of neoadjuvant Sacituzumab govitecan for localized TNBC
errCANCER RESEARCH
IF16.6
err2024-02-01
err0
PREAI
errSpring, Laura M.; Wu, Bogang; Liu, Ting; Geisberg, Jacob; Cristea, Simona; Bossuyt, Veerle; Abelman, Rachel Occhiogrosso; Peiris, Nicole; Coates, James; Koh, Siang-Boon; Zhang, Mengran; Ryan, Lianne; Moy, Beverly; Isakoff, Steven J.; Tolaney, Sara M.; Michor, Franziska; Bardia, Aditya; Ellisen, Leif W.
err分享
err收藏
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations变构PI3Kα 抑制克服了继发性PIK3CA突变介导的对正构抑制剂的靶向抗性
errCANCER DISCOVERY
IF33.3
err2023-10-31
err14
errOAAI
errVarkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Stavridi, Anastasia-Maria; Yuan, Xin; Kim, Janice S.; Ellis, Haley; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian P.; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg M.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Del Vecchio, Kathryn; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan
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err收藏

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