Michael S. Lawrence - Publications, H-index & Citations

Michael S. Lawrence

harvard medical school

145H指数

648论文数

18.9W被引数

收录论文 122

发表时间

Gene clustering drives the transcriptional coherence of disparate biological processes in eukaryotes 基因聚类驱动真核生物中不同生物过程的转录一致性

iScience

IF4.1

2026-07-25

OAAI

Richard I. Joh; Michael S. Lawrence; Martin J. Aryee; Mo Motamedi

RB loss modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions RB loss调节染色质组织，通过调控cohesin依赖性环和增强子-启动子相互作用。

Nature Communications

IF15.7

2026-04-08

OAAI

Hanjun Lee; Ioanna-Maria Gkotinakou; Connor G. McGrath; Badri Krishnan; Sambhavi Animesh; Isabella Salinas; Robert Morris; Moshe Sade-Feldman; Wilhelm Hass; Michael S. Lawrence; Ioannis Sanidas

Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity 可遗传的染色质接触变化与跨代对饮食诱导的胰岛素失调和肥胖的易感性相关

Nature Communications

IF15.7

2026-02-12

OAAI

Richard C. Chang; Riann J. Egusquiza; Angélica Amorim Amato; Zhuorui Li; Alivia L. Dougherty; Kaitlin T. To; Michelle Avila; Erika M. Joloya; Hailey B. Wheeler; Angela Nguyen; Keiko Shioda; Junko Odajima; Michael S. Lawrence; Toshi Shioda; Bruce Blumberg

Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection

JNCI-Journal of the National Cancer Institute

IF7.2

2025-11-01

PREAI

Das, Dipon; Hirayama, Shun; Aye, Ling; Bryan, Michael E.; Naegele, Saskia; Zhao, Brian; Efthymiou, Vasileios; Mendel, Julia; Fisch, Adam S.; Guan, Zoe; Kroller, Lea; Michels, Birgitta E.; Waterboer, Tim; Richmon, Jeremy D.; Adalsteinsson, Viktor; Lawrence, Michael S.; Crowson, Matthew G.; Iafrate, A. John; Faden, Daniel L.

Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma

BLOOD CANCER JOURNAL

IF11.6

2024-08-27

OAAI

Bai, Baoyan; Wise, Jillian F.; Vodak, Daniel; Nakken, Sigve; Sharma, Ankush; Blaker, Yngvild Nuvin; Brodtkorb, Marianne; Hilden, Vera; Troen, Gunhild; Ren, Weicheng; Lorenz, Susanne; Lawrence, Michael S.; Myklebost, Ola; Kimby, Eva; Pan-Hammarstrom, Qiang; Steen, Chloe B.; Meza-Zepeda, Leonardo A.; Beiske, Klaus; Smeland, Erlend B.; Hovig, Eivind; Lingjaerde, Ole Christian; Holte, Harald; Myklebust, June Helen

Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy (vol 82, pg 773, 2022)

CANCER RESEARCH

IF16.6

2024-05-02

OAAI

Zhang, Songfa; Yan, Chuan; Millar, David G.; Yang, Qiqi; Heather, James M.; Langenbucher, Adam; Morton, Laura T.; Sepulveda, Sean; Alpert, Eric; Whelton, Lauren R.; Zarrella, Dominique T.; Guo, Mei; Minogue, Eleanor; Lawrence, Michael S.; Rueda, Bo R.; Spriggs, David R.; Lu, Weiguo; Langenau, David M.; Cobbold, Mark

Patterns in the tapestry of chromatin-bound RB

TRENDS IN CELL BIOLOGY

IF18.1

2024-04-01

OAAI

Sanidas, Ioannis; Lawrence, Michael S.; Dyson, Nicholas J.

RB represses cohesin-dependent loop formation and activates E2Findependent transcription

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Lee, Hanjun; Gkotinakou, Ioanna-Maria; Krishnan, Badri; Dyson, Nicholas J.; Lawrence, Michael S.; Sanidas, Ioannis

APOBEC3A drives tumor evolution through activation of ERVs in non small cell lung cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Isozaki, Hideko; Sakhtemani, Ramin; Nikpour, Naveed; Monroe, Susanna; Lawrence, Michael; Hata, Aaron

Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations

NATURE COMMUNICATIONS

IF15.7

2024-03-18

OAAI

Butt, Yasha; Sakhtemani, Ramin; Mohamad-Ramshan, Rukshana; Lawrence, Michael S.; Bhagwat, Ashok S.

Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes

NATURE COMMUNICATIONS

IF15.7

2024-03-18

OAAI

Sanchez, Ambrocio; Ortega, Pedro; Sakhtemani, Ramin; Manjunath, Lavanya; Oh, Sunwoo; Bournique, Elodie; Becker, Alexandrea; Kim, Kyumin; Durfee, Cameron; Temiz, Nuri Alpay; Chen, Xiaojiang S.; Harris, Reuben S.; Lawrence, Michael S.; Buisson, Remi

Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs

CANCER DISCOVERY

IF33.3

2024-02-21

OAAI

Choudhuri, Shreoshi Pal; Girard, Luc; Lim, Jun Yi Stanley; Wise, Jillian F.; Freitas, Braeden; Yang, Di; Wong, Edmond; Hamilton, Seth; Chien, Victor D.; Kim, Yoon Jung; Gilbreath, Collin; Zhong, Jun; Phat, Sarah; Myers, David T.; Christensen, Camilla L.; Mazloom-Farsibaf, Hanieh; Stanzione, Marcello; Wong, Kwok-Kin; Hung, Yin P.; Farago, Anna F.; Meador, Catherine B.; Dyson, Nicholas J.; Lawrence, Michael S.; Wu, Sihan; Drapkin, Benjamin J.

APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability APOBEC3A通过PRIMPOL诱导DNA缺口并赋予缺口相关的治疗脆弱性

SCIENCE ADVANCES

IF12.5

2024-01-19

OAAI

Kawale, Ajinkya S.; Ran, Xiaojuan; Patel, Parasvi S.; Saxena, Sneha; Lawrence, Michael S.; Zou, Lee

Revisiting the use of structural similarity index in Hi-C

NATURE GENETICS

IF31.8

2023-12-05

OAAI

Lee, Hanjun; Blumberg, Bruce; Lawrence, Michael S.; Shioda, Toshihiro

Epigenetic regulation of APOBEC3A mutagenesis and tumor evolution during targeted therapy in non-small cell lung cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Isozaki, Hideko; Sakhtemani, Ramin; Nikpour, Naveed; Monroe, Susanna; Lin, Jessica; Sequist, Lecia; Piotrowska, Zofia; Gainor, Justin; Buisson, Remi; Lawrence, Michael; Hata, Aaron

Genomics and transcriptomics profiling of BRCA mutation carriers revealed the landscape of early pathogenesis of BRCA1/2-associated breast cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Ren, Zuen; Lin, Po-Han; Koh, Siang Boon; Stewart, Kai; Haradhvala, Nick; Dedeoglu, Aylin S.; Smidt, Ilze; Suzuki, Akiko; Li, David; Thant, Win; Mueller, Sarah; Joseph, Taisha; Bossuyt, Veerle; Lawrence, Michael; Getz, Gad; Ellisen, Leif W.

The non-canonical role of Rb in enhancers and insulators

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Lee, Hanjun; Gkotinakou, Ioanna M.; Sanidas, Ioannis; Lawrence, Michael S.; Dyson, Nicholas J.

TGF β in the microenvironment induces a physiologically occurring immune-suppressive senescent state

CELL REPORTS

IF6.9

2023-03-01

OAAI

Matsuda, Satoru; Revandkar, Ajinkya; Dubash, Taronish D.; Ravi, Arvind; Wittner, Ben S.; Lin, Maoxuan; Morris, Robert; Burr, Risa; Guo, Hongshan; Seeger, Karsen; Szabolcs, Annamaria; Che, Dante; Nieman, Linda; Getz, Gad A.; Ting, David T.; Lawrence, Michael S.; Gainor, Justin; Haber, Daniel A.; Maheswaran, Shyamala

Hypomethylation of immune-related loci contribute to prostate tumorigenesis

CANCER RESEARCH

IF16.6

2023-01-15

PREAI

Haber, Daniel A.; Guo, Hongshan; Wittner, Ben S.; Vuille, Joanna A.; Lawrence, Michael S.; Wu, Chin-Lee; Toner, Mehmet; Miyamoto, David T.; Maheswaran, Shyamala

Pathway and network analysis of more than 2500 whole cancer genomes (vol 11, 729, 2020)超过2500个全癌症基因组的通路和网络分析 (第11卷，729，2020)

NATURE COMMUNICATIONS

IF15.7

2022-12-08

OAAI

Reyna, Matthew A.; Haan, David; Paczkowska, Marta; Verbeke, Lieven P. C.; Vazquez, Miguel; Kahraman, Abdullah; Pulido-Tamayo, Sergio; Barenboim, Jonathan; Wadi, Lina; Dhingra, Priyanka; Shrestha, Raunak; Getz, Gad; Lawrence, Michael S.; Pedersen, Jakob Skou; Rubin, Mark A.; Wheeler, David A.; Brunak, Sren; Izarzugaza, Jose M. G.; Khurana, Ekta; Marchal, Kathleen; von Mering, Christian; Sahinalp, S. Cenk; Valencia, Alfonso; Reimand, Jueri; Stuart, Joshua M.; Raphael, Benjamin J.

研究方向