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Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease Xia, Zengjie; Prescott, Emily E.; Urbanek, Agnieszka; Wareing, Hollie E.; King, Marianne C.; Olerinyova, Anna; Dakin, Helen; Leah, Tom; Barnes, Katy A.; Matuszyk, Martyna M.; Dimou, Eleni; Hidari, Eric; Zhang, Yu P.; Lam, Jeff Y. L.; Danial, John S. H.; Strickland, Michael R.; Jiang, Hong; Thornton, Peter; Crowther, Damian C.; Ohtonen, Sohvi; Gomez-Budia, Mireia; Bell, Simon M.; Ferraiuolo, Laura; Mortiboys, Heather; Higginbottom, Adrian; Wharton, Stephen B.; Holtzman, David M.; Malm, Tarja; Ranasinghe, Rohan T.; Klenerman, David; De, Suman 分享 收藏
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The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia Nichols, Emma; Merrick, Richard; Hay, Simon, I; Himali, Dibya; Himali, Jayandra J.; Hunter, Sally; Keage, Hannah A. D.; Latimer, Caitlin S.; Scott, Matthew R.; Steinmetz, Jaimie; Walker, Jamie M.; Wharton, Stephen B.; Wiedner, Crystal; Crane, Paul K.; Keene, Dirk; Launer, Lenore J.; Matthews, Fiona E.; Schneider, Julie; Seshadri, Sudha; White, Lon; Brayne, Carol; Vos, Theo 分享 收藏
Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development Williamson, Daniel; Schwalbe, Edward C.; Aldinger, Kimberly A.; Hicks, Debbie; Lindsey, Janet C.; Crosier, Stephen; Richardson, Stacey; Goddard, Jack; Hill, Rebecca M.; Castle, Jemma; Grabovska, Yura; Hacking, James; Pizer, Barry; Wharton, Stephen B.; Jacques, Thomas S.; Joshi, Abhijit; Bailey, Simon; Clifford, Steven C. 分享 收藏
Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP 在TARDBP中携带p.Y374X截短突变的ALS系谱中的非典型TDP-43蛋白表达 Cooper-Knock, Johnathan; Julian, Thomas H.; Feneberg, Emily; Highley, J. Robin; Sidra, Maurice; Turner, Martin R.; Talbot, Kevin; Ansorge, Olaf; Allen, Scott P.; Moll, Tobias; Shelkovnikova, Tatyana; Castelli, Lydia; Hautbergue, Guillaume M.; Hewitt, Christopher; Kirby, Janine; Wharton, Stephen B.; Mead, Richard J.; Shaw, Pamela J. 分享 收藏
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke Hase, Yoshiki; Ameen-Ali, Kamar E.; Waller, Rachel; Simpson, Julie E.; Stafford, Charlotte; Mahesh, Ayushi; Ryan, Lucy; Pickering, Lucy; Bodman, Caroline; Hase, Mai; Boche, Delphine; Horsburgh, Karen; Wharton, Stephen B.; Kalaria, Raj N. 分享 收藏
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts 阿尔茨海默病神经病理学范围内晚期神经病理学变化的频率: 来自13个基于社区或基于人群的尸检队列的综合数据 Nelson, Peter T.; Brayne, Carol; Flanagan, Margaret E.; Abner, Erin L.; Agrawal, Sonal; Attems, Johannes; Castellani, Rudolph J.; Corrada, Maria M.; Cykowski, Matthew D.; Di, Jing; Dickson, Dennis W.; Dugger, Brittany N.; Ervin, John F.; Fleming, Jane; Graff-Radford, Jonathan; Grinberg, Lea T.; Hokkanen, Suvi R. K.; Hunter, Sally; Kapasi, Alifiya; Kawas, Claudia H.; Keage, Hannah A. D.; Keene, C. Dirk; Kero, Mia; Knopman, David S.; Kouri, Naomi; Kovacs, Gabor G.; Labuzan, Sydney A.; Larson, Eric B.; Latimer, Caitlin S.; Leite, Renata E. P.; Matchett, Billie J.; Matthews, Fiona E.; Merrick, Richard; Montine, Thomas J.; Murray, Melissa E.; Myllykangas, Liisa; Nag, Sukriti; Nelson, Ruth S.; Neltner, Janna H.; Nguyen, Aivi T.; Petersen, Ronald C.; Polvikoski, Tuomo; Reichard, R. Ross; Rodriguez, Roberta D.; Suemoto, Claudia K.; Wang, Shih-Hsiu J.; Wharton, Stephen B.; White, Lon; Schneider, Julie A. 分享 收藏
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Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity Perez-Nievas, Beatriz G.; Johnson, Louisa; Beltran-Lobo, Paula; Hughes, Martina M.; Gammallieri, Luciana; Tarsitano, Francesca; Myszczynska, Monika A.; Vazquez-Villasenor, Irina; Jimenez-Sanchez, Maria; Troakes, Claire; Wharton, Stephen B.; Ferraiuolo, Laura; Noble, Wendy 分享 收藏
Dementia in the older population is associated with neocortex content of serum amyloid P component Ellmerich, Stephan; Taylor, Graham W.; Richardson, Connor D.; Minett, Thais; Schmidt, Amand Floriaan; Brayne, Carol; Matthews, Fiona E.; Ince, Paul G.; Wharton, Stephen B.; Pepys, Mark B. 分享 收藏
Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse 髓母细胞瘤复发时可行的遗传驱动因素的出现和维持 Richardson, Stacey; Hill, Rebecca M.; Kui, Christopher; Lindsey, Janet C.; Grabovksa, Yura; Keeling, Claire; Pease, Louise; Bashton, Matthew; Crosier, Stephen; Vinci, Maria; Andre, Nicolas; Figarella-Branger, Dominique; Hansford, Jordan R.; Lastowska, Maria; Zakrzewski, Krzysztof; Jorgensen, Mette; Pickles, Jessica C.; Taylor, Michael D.; Pfister, Stefan M.; Wharton, Stephen B.; Pizer, Barry; Michalski, Antony; Joshi, Abhijit; Jacques, Thomas S.; Hicks, Debbie; Schwalbe, Edward C.; Williamson, Daniel; Ramaswamy, Vijay; Bailey, Simon; Clifford, Steven C. 分享 收藏
Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics Crosier, Stephen; Hicks, Debbie; Schwalbe, Edward C.; Williamson, Daniel; Leigh Nicholson, Sarah; Smith, Amanda; Lindsey, Janet C.; Michalski, Antony; Pizer, Barry; Bailey, Simon; Bown, Nick; Cuthbert, Gavin; Wharton, Stephen B.; Jacques, Thomas S.; Joshi, Abhijit; Clifford, Steven C. 分享 收藏
Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer's and small vessel disease pathologies 衰老白质中细胞炎症反应的异质性以及与阿尔茨海默氏病和小血管病变的关系 Waller, Rachel; Narramore, Ruth; Simpson, Julie E.; Heath, Paul R.; Verma, Nikita; Tinsley, Megan; Barnes, Jordan R.; Haris, Hanna T.; Henderson, Frances E.; Matthews, Fiona E.; Richardson, Connor D.; Brayne, Carol; Ince, Paul G.; Kalaria, Raj N.; Wharton, Stephen B. 分享 收藏
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study Hill, Rebecca M.; Richardson, Stacey; Schwalbe, Edward C.; Hicks, Debbie; Lindsey, Janet C.; Crosier, Stephen; Rafiee, Gholamreza; Grabovska, Yura; Wharton, Stephen B.; Jacques, Thomas S.; Michalski, Antony; Joshi, Abhijit; Pizer, Barry; Williamson, Daniel; Bailey, Simon; Clifford, Steven C. 分享 收藏
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes 婴儿髓母细胞瘤的分子景观和相关临床经验: 第二代亚型的预后意义 Hicks, D.; Rafiee, G.; Schwalbe, E. C.; Howell, C., I; Lindsey, J. C.; Hill, R. M.; Smith, A. J.; Adidharma, P.; Steel, C.; Richardson, S.; Pease, L.; Danilenko, M.; Crosier, S.; Joshi, A.; Wharton, S. B.; Jacques, T. S.; Pizer, B.; Michalski, A.; Williamson, D.; Bailey, S.; Clifford, S. C. 分享 收藏
Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia Sharp, Matthew MacGregor; Saito, Satoshi; Keable, Abby; Gatherer, Maureen; Aldea, Roxana; Agarwal, Nivedita; Simpson, Julie E.; Wharton, Stephen B.; Weller, Roy O.; Carare, Roxana O. 分享 收藏
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