Nathan K. Yee - Publications, H-index & Citations

Nathan K. Yee

Boehringer Ingelheim

42H指数

240论文数

5.4K被引数

收录论文 90

发表时间

SWEET BUT SOUR: THE BITTER TRUTH BEHIND SGLT2 INHIBITORS AND DKA

CHEST

IF8.6

2024-10-01

PREAI

Chua, Janice Loren; Vintch, Janine R.; Yee, Nathan

Nectin-4 targeted therapy with MMAE protodrug results in anti-tumor efficacy mediated by click chemistry

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Coricor, George; McFarland, Jesse M.; Srinivasan, Sangeetha; Wagner, Stefanie; Yee, Nathan; Tri-Hung Nguyen; Oneto, Jose M. Mejia

Novel Insights from Clinical Practice Autologous Blood Patch Pleurodesis and Endobronchial Valves for Management of Persistent Air Leaks in Two Cases of Tuberculosis

RESPIRATION

IF3.8

2024-02-28

PREAI

Martinez, Aida F.; Tom, Zachary; Hsia, David W.; Vintch, Janine; Yee, Nathan

Retracted Covid-19 articles: significantly more cited than other articles within their journal of origin

SCIENTOMETRICS

IF3.5

2023-04-12

OAAI

Taros, Trenton; Zoppo, Christopher; Yee, Nathan; Hanna, Jack; MacGinnis, Christine

PHARMACOKINETIC AND IMMUNOLOGIC DATA FROM A PHASE I STUDY OF THE CLICK CHEMISTRY-BASED THERAPY SQ3370 IN ADVANCED SOLID TUMORS AND SOFT-TISSUE SARCOMA PROVIDES PROOF-OF-CONCEPT FOR THE CAPAC PLATFORM

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

Bhadri, Vivek; Subbiah, Vivek; Strauss, James; Chawla, Sant; Bui, Nam; Kwatra, Vineet; Weiss, Mia; Batty, Kathleen; Zakharian, Michael; Oneto, Jose Mejia; Srinivasan, Sangeetha; Yee, Nathan; Wilson, Rosalind; Saville, M. Wayne; Guminski, Alexander

SQ3370 enhances the safety and therapeutic index of cytotoxic agents via local activation therapy with improved local and systemic immune response

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Yee, Nathan; Srinivasan, Sangeetha; Mahmoodi, Amir; Zakharian, Michael; Royzen, Maksim; Oneto, Jose Mejia

Sulfone-Mediated SNAr Reaction as a Powerful Tool for the Synthesis of 4-Quinolinyl Ethers and More-Application to the Synthesis of HCV NS3/4a Protease Inhibitor BI 201420

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2020-05-28

PREAI

Patel, Nitinchandra D.; Wei, Xudong; Byrne, Denis; Narayanan, Bikshandarkoil A.; Pennino, Scott; Sarvestani, Max; Saha, Anjan; Haddad, Nizar; Kapadia, Suresh; Lorenz, Jon C.; DeCroos, Philomen; Ye, Andrew; Lee, Heewon; Grinberg, Nelu; Hossain, Azad; Busacca, Carl A.; Yee, Nathan K.; Senanayake, Chris H.

Nickel-Catalyzed Cross-Electrophile Reductive Couplings of Neopentyl Bromides with Aryl Bromides

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2020-05-26

PREAI

Biswas, Soumik; Qu, Bo; Desrosiers, Jean-Nicolas; Choi, Younggi; Haddad, Nizar; Yee, Nathan K.; Song, Jinghua J.; Senanayake, Chris H.

Application of a Preformed Pd-BIDIME Precatalyst to Suzuki-Miyaura Cross-Coupling Reaction in Flow

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2019-02-04

PREAI

Sieber, Joshua D.; Buono, Frederic; Brusoe, Andrew; Desrosiers, Jean-Nicolas; Haddad, Nizar; Lorenz, Jon C.; Xu, Yibo; Wu, Hao; Zhang, Li; Han, Zhengxu Steve; Roschangar, Frank; Song, Jinhua J.; Yee, Nathan K.; Senanayake, Chris H.

Local drug activation: Making cytotoxics safer for local tumors

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Srinivasan, Sangeetha; Dela Cruz, Filemon; Kung, Andrew; Gaviria, Ervin; Miller, Ethan; Yee, Nathan; Royzen, Maksim; Mejia-Oneto, Jose

Enantioselective Synthesis of α-(Hetero)aryl Piperidines through Asymmetric Hydrogenation of Pyridinium Salts and Its Mechanistic Insights

ORGANIC LETTERS

IF5

2018-02-20

OAAI

Qu, Bo; Mangunuru, Hari P. R.; Tcyrulnikov, Sergei; Rivalti, Daniel; Zatolochnaya, Olga V.; Kurouski, Dmitry; Radomkit, Suttipol; Biswas, Soumik; Karyakarte, Shuklendu; Fandrick, Keith R.; Sieber, Joshua D.; Rodriguez, Sonia; Desrosiers, Jean-Nicolas; Haddad, Nizar; McKellop, Keith; Pennino, Scott; Lee, Heewon; Yee, Nathan K.; Song, Jinhua J.; Kozlowski, Marisa C.; Senanayake, Chris H.

Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2018-01-23

PREAI

Sieber, Joshua D.; Rodriguez, Sonia; Frutos, Rogelio; Buono, Frederic; Zhang, Yongda; Li, Ning; Qu, Bo; Premasiri, Ajith; Li, Zhibin; Han, Zhengxu S.; Xu, Yibo; Byrne, Denis; Haddad, Nizar; Lorenz, Jon; Grinberg, Nelu; Kurouski, Dmitry; Lee, Heewon; Narayanan, Bikshandarkoil; Nummy, Laurence; Mulder, Jason; Brown, Jack D.; Granger, Alice; Gao, Joe; Krawiec, Mariusz; Williams, Zeena; Pennino, Scott; Song, Jinhua J.; Hossain, Azad; Yee, Nathan K.; Busacca, Carl; Roschangar, Frank; Xin, Yanchao; Mao, Zhantong; Zhang, Xinzhu; Hong, Yaping; Senanayake, Chris H.

Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution

CHEMICAL SCIENCE

IF7.4

2018-01-01

OAAI

Zatolochnaya, Olga V.; Rodriguez, Sonia; Zhang, Yongda; Lao, Kendricks S.; Tcyrulnikov, Sergei; Li, Guisheng; Wang, Xiao-Jun; Qu, Bo; Biswas, Soumik; Mangunuru, Hari P. R.; Rivalti, Daniel; Sieber, Joshua D.; Desrosiers, Jean-Nicolas; Leung, Joyce C.; Grinberg, Nelu; Lee, Heewon; Haddad, Nizar; Yee, Nathan K.; Song, Jinhua J.; Kozlowski, Marisa C.; Senanayake, Chris H.

Early Development Scale-Up of a Structurally-Challenging 5-Lipoxygenase Activating Protein (FLAP) Inhibitor

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2017-07-18

PREAI

Mulder, Jason A.; Gao, Joe; Fandrick, Keith R.; Zeng, Xingzhong; Desrosiers, Jean-Nicolas; Patel, Nitinchandra D.; Li, Zhibin; Rodriguez, Sonia; Lorenz, Jon C.; Wang, Jun; Ma, Shengli; Fandrick, Daniel R.; Grinberg, Nelu; Lee, Heewon; Bosanac, Todd; Takahashi, Hidenori; Chen, Zhidong; Bartolozzi, Alessandra; Nemoto, Peter; Busacca, Carl A.; Song, Jinhua J.; Yee, Nathan K.; Mahoney, Paige E.; Senanayake, Chris H.

Enantioselective Nickel-Catalyzed Mizoroki Heck Cyclizations To Generate Quaternary Stereocenters

ORGANIC LETTERS

IF5

2017-06-12

OAAI

Desrosiers, Jean-Nicolas; Wen, Jialin; Tcyrulnikov, Sergei; Biswas, Soumik; Qu, Bo; Hie, Liana; Kurouski, Dmitry; Wu, Ling; Grinberg, Nelu; Haddad, Nizar; Busacca, Carl A.; Yee, Nathan K.; Song, Jinhua J.; Garg, Neil K.; Zhang, Xumu; Kozlowski, Marisa C.; Senanayake, Chris H.

Synthesis of P-Chiral Dihydrobenzooxaphosphole Core for BI Ligands in Asymmetric Transformations

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2017-05-05

PREAI

Li, Guisheng; Wang, Xiao-Jun; Zhang, Yongda; Tan, Zhulin; DeCroos, Philomen; Lorenz, Jon C.; Wei, Xudong; Grinberg, Nelu; Yee, Nathan K.; Senanayake, Chris H.

Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

GREEN CHEMISTRY

IF9.2

2017-01-01

PREAI

Marsini, Maurice A.; Buono, Frederic G.; Lorenz, Jon C.; Yang, Bing-Shiou; Reeves, Jonathan T.; Sidhu, Kanwar; Sarvestani, Max; Tan, Zhulin; Zhang, Yongda; Li, Ning; Lee, Heewon; Brazzillo, Jason; Nummy, Laurence J.; Chung, J. C.; Luvaga, Irungu K.; Narayanan, Bikshandarkoil A.; Wei, Xudong; Song, Jinhua J.; Roschangar, Frank; Yee, Nathan K.; Senanayake, Chris H.

Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-11-17

OAAI

Wei, Xudong; Qu, Bo; Zeng, Xingzhong; Savoie, Jolaine; Fandrick, Keith R.; Desrosiers, Jean -Nicolas; Tcyrulnikov, Sergei; Marsini, Maurice A.; Buono, Frederic G.; Li, Zhibin; Yang, Bing-Shiou; Tang, Wenjun; Haddad, Nizar; Gutierrez, Osvaldo; Wang, Jun; Lee, Heewon; Ma, Shengli; Campbell, Scot; Lorenz, Jon C.; Eckhardt, Matthias; Himmelsbach, Frank; Peters, Stefan; Patel, Nitinchandra D.; Tan, Zhulin; Yee, Nathan K.; Song, Jinhua J.; Roschangar, Frank; Kozlowski, Marisa C.; Senanayake, Chris H.

Reengineered BI-DIME Ligand Core Based on Computer Modeling to Increase Selectivity in Asymmetric Suzuki-Miyaura Coupling for the Challenging Axially Chiral HIV Integrase Inhibitor

ADVANCED SYNTHESIS & CATALYSIS

IF4

2016-09-27

PREAI

Haddad, Nizar; Mangunuru, Hari P. R.; Fandrick, Keith R.; Qu, Bo; Sieber, Joshua D.; Rodriguez, Sonia; Desrosiers, Jean-Nicolas; Patel, Nitinchandra D.; Lee, Heewon; Kurouski, Dmitry; Grinberg, Nelu; Yee, Nathan K.; Song, Jinhua J.; Senanayake, Chris H.

Synthesis of Enantioenriched 2-Alkyl Piperidine Derivatives through Asymmetric Reduction of Pyridinium Salts

ORGANIC LETTERS

IF5

2016-09-23

OAAI

Qu, Bo; Mangunuru, Hari P. R.; Wei, Xudong; Fandrick, Keith R.; Desrosiers, Jean-Nicolas; Sieber, Joshua D.; Kurouski, Dmitry; Haddad, Nizar; Samankumara, Lalith P.; Lee, Heewon; Savoie, Jolaine; Ma, Shengli; Grinberg, Nelu; Sarvestani, Max; Yee, Nathan K.; Song, Jinhua J.; Senanayake, Chris H.

研究方向