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I

Ian Zachary

5 university street

67H指数
176论文数
1.4W被引数
收录论文 69
发表时间
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Quinoline-Based Neuropilin-1 Antagonists Exhibit a Pure Antagonist Profile and Block Vascular Endothelial Growth Factor-Induced Pain喹啉类神经毡蛋白-1拮抗剂表现出纯拮抗剂特性并阻断血管内皮生长因子诱导的疼痛
errACS Pharmacology & Translational Science
IF3.7
err2025-10-29
err0
errOAAI
errSara Hestehave; Silvia Dragoni; Philip Fallon; Filipa Mota; Aida Calderon-Rivera; Kimberly Gomez; Jonathan Powell; Anastasia Patsiarika; Tifelle Reisinger; Stuart Crosby; A.W. Edith Chan; David Steadman; Natalie Winfield; Ashley Jarvis; John Martin; Ian C. Zachary; Paul Frankel; Snezana Djordjevic; Christiana Ruhrberg; Rajesh Khanna; David L. Selwood
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Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction母体PlGF和脐带多普勒可预测早发型胎儿生长受限的妊娠结局
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-09-15
err6
errOAAI
errSpencer, Rebecca; Maksym, Kasia; Hecher, Kurt; Marsal, Karel; Figueras, Francesc; Ambler, Gareth; Whitwell, Harry; Nene, Nuno Rocha; Sebire, Neil J.; Hansson, Stefan R.; Diemert, Anke; Brodszki, Jana; Gratacos, Eduard; Ginsberg, Yuval; Weissbach, Tal; Peebles, Donald M.; Zachary, Ian; Marlow, Neil; Huertas-Ceballos, Angela; David, Anna L.
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Macrophage-specific deletion of neuropilin-2 inhibits inflammatory signalling and attenuates atherosclerotic plaque development in apoe-deficient mice巨噬细胞特异性neuropilin-2缺失抑制apoe缺陷小鼠的炎症信号传导并减轻动脉粥样硬化斑块的发展
errHEART
IF4.4
err2023-06-02
err0
errOAAI
errPellet-Many, Caroline; Fernando-Sayers, Jacob; Zachary, Ian
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Mechanisms of Acquired Resistance to Anti-VEGF Therapy for Neovascular Eye Diseases新生血管性眼病抗VEGF治疗的获得性耐药机制
errINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
err2023-05-30
err23
errOAAI
errSharma, Dhyana; Zachary, Ian; Jia, Haiyan
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The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function
errJOURNAL OF CELL SCIENCE
IF3.6
err2023-05-25
err2
errOAAI
errCritchley, William R.; Smith, Gina A.; Zachary, Ian C.; Harrison, Michael A.; Ponnambalam, Sreenivasan
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Neuropilin-1 Signaling through p130Cas Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err106
errOAAI
errEvans, Ian M.; Yamaji, Maiko; Britton, Gary; Pellet-Many, Caroline; Lockie, Claire; Zachary, Ian C.; Frankel, Paul
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Endothelial C-Type Natriuretic Peptide Is a Critical Regulator of Angiogenesis and Vascular Remodeling
errCIRCULATION
IF38.6
err2019-03-26
err66
errOAAI
errBubb, Kristen J.; Aubdool, Aisah A.; Moyes, Amie J.; Lewis, Sarah; Drayton, Jonathan P.; Tang, Owen; Mehta, Vedanta; Zachary, Ian C.; Abraham, David J.; Tsui, Janice; Hobbs, Adrian J.
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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
errAMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
IF4.7
err2019-03-01
err9
errOAAI
errMahmoud, Marwa; Evans, Ian M.; Mehta, Vedanta; Pellet-Many, Caroline; Paliashvili, Ketevan; Zachary, Ian
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Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heartNeuropilin 1介导再生斑马鱼心脏的心外膜激活和血运重建
errDEVELOPMENT
IF3.6
err2019-01-01
err21
errOAAI
errLowe, Vanessa; Wisniewski, Laura; Sayers, Jacob; Evans, Ian; Frankel, Paul; Mercader-Huber, Nadia; Zachary, Ian C.; Pellet-Many, Caroline
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VEGF (Vascular Endothelial Growth Factor) Induces NRP1 (Neuropilin-1) Cleavage via ADAMs (a Disintegrin and Metalloproteinase) 9 and 10 to Generate Novel Carboxy-Terminal NRP1 Fragments That Regulate Angiogenic Signaling
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2018-08-01
err37
errOAAI
errMehta, Vedanta; Fields, Laura; Evans, Ian M.; Yamaji, Maiko; Pellet-Many, Caroline; Jones, Timothy; Mahmoud, Marwa; Zachary, Ian
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Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production in Regulatory T-Cells
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2018-04-12
err62
errOAAI
errPowell, Jonathan; Mota, Filipa; Steadman, David; Soudy, Christelle; Miyauchi, Jeremy T.; Crosby, Stuart; Jarvis, Ashley; Reisinger, Tifelle; Winfield, Natalie; Evans, Graham; Finniear, Aled; Yelland, Tamas; Chou, Yi-Tai; Chan, A. W. Edith; O'Leary, Andrew; Cheng, Lili; Liu, Dan; Fotinou, Constantina; Milagre, Carla; Martin, John F.; Jin, Haiyan; Franke, Paul; Djordjevic, Snezana; Tsirka, Stella E.; Zachary, Ian C.; Selwood, David L.
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Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking受体酪氨酸激酶在信号转导和受体运输中的泛素化和去泛素化
errCELLS
IF5.2
err2018-03-15
err44
errOAAI
errCritchley, William R.; Pellet-Many, Caroline; Ringham-Terry, Benjamin; Harrison, Michael A.; Zachary, Ian C.; Ponnambalam, Sreenivasan
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Architecture and hydration of the arginine-binding site of neuropilin-1
errFEBS JOURNAL
IF4.2
err2018-02-25
err24
errOAAI
errMota, Filipa; Fotinou, Constantina; Rana, Rohini R.; Chan, A. W. Edith; Yelland, Tamas; Arooz, Mohamed T.; O'Leary, Andrew P.; Hutton, Jennie; Frankel, Paul; Zachary, Ian; Selwood, David; Djordjevic, Snezana
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Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2017-02-01
err22
errOAAI
errEvans, Ian M.; Kennedy, Susan A.; Paliashvili, Ketevan; Santra, Tapesh; Yamaji, Maiko; Lovering, Ruth C.; Britton, Gary; Frankel, Paul; Kolch, Walter; Zachary, Ian C.
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Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling
errSCIENTIFIC REPORTS
IF3.9
err2016-06-13
err38
errOAAI
errFrolov, Antonina; Evans, Ian M.; Li, Ningning; Sidlauskas, Kastytis; Paliashvili, Ketevan; Lockwood, Nicola; Barrett, Angela; Brandner, Sebastian; Zachary, Ian C.; Frankel, Paul
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Peri- and Postnatal Effects of Prenatal Adenoviral VEGF Gene Therapy in Growth-Restricted Sheep
errBIOLOGY OF REPRODUCTION
IF3
err2016-06-01
err40
errOAAI
errCarr, David J.; Wallace, Jacqueline M.; Aitken, Raymond P.; Milne, John S.; Martin, John F.; Zachary, Ian C.; Peebles, Donald M.; David, Anna L.
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Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket
errFEBS JOURNAL
IF4.2
err2016-04-01
err16
errOAAI
errTsai, Yi-Chun Isabella; Fotinou, Constantina; Rana, Rohini; Yelland, Tamas; Frankel, Paul; Zachary, Ian; Djordjevic, Snezana
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NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells (vol 11, pg 1577, 2015)NRP1调节CDC42活化以促进内皮尖端细胞中的丝状伪足形成 (第11卷，1577页，2015)
errCELL REPORTS
IF6.9
err2015-12-01
err0
errOAAI
errFantin, Alessandro; Lampropoulou, Anastasia; Gestri, Gaia; Raimondi, Claudio; Senatore, Valentina; Zachary, Ian; Ruhrberg, Christiana
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NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip CellsNRP1调节CDC42活化促进内皮细胞丝足形成
errCELL REPORTS
IF6.9
err2015-06-01
err81
errOAAI
errFantin, Alessandro; Lampropoulou, Anastasia; Gestri, Gaia; Raimondi, Claudio; Senatore, Valentina; Zachary, Ian; Ruhrberg, Christiana
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VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2014-08-15
err37
errOAAI
errFearnley, Gareth W.; Odell, Adam F.; Latham, Antony M.; Mughal, Nadeem A.; Bruns, Alexander F.; Burgoyne, Nicholas J.; Homer-Vanniasinkam, Shervanthi; Zachary, Ian C.; Hollstein, Monica C.; Wheatcroft, Stephen B.; Ponnambalam, Sreenivasan
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