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Zishuo Cheng

sanofi r&d, framingham, massachusetts 01701, united states

19H指数
40论文数
1.1K被引数
收录论文 28
发表时间
Stress-Induced Antibody Aggregates: Insights from Native SEC-MS with Postcolumn Denaturation压力诱导的抗体聚集物:来自原位SEC-MS与柱后变性实验的见解
err2025-12-09
err0
errOAAI
errDaniil Ivanov; Christine Lee; Dennis Delgado; Luke Brewer; Julie Corbo; Christopher Fitzpatrick; Zishuo Cheng; Karen Albee; Karen Lee; Fatemeh Tousi
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Inhibitor Affinity Differs among Clinical Variants of IMP Metallo-β-Lactamases: Analysis and Implications for Inhibitor Design抑制剂亲和力在不同临床类型的IMP金属-β-内酰胺酶之间存在差异:分析与抑制剂设计的意义
err2025-07-24
err0
PREAI
errCaitlyn A. Thomas; John Paul Alao; Thomas Smisek; Zishuo Cheng; Christopher R. Bethel; Kundi Yang; Ikponwmosa Obaseki; Richard C. Page; Robert A. Bonomo; Peter Oelschlaeger; Walter Fast; Andrea N. Kravats; Michael W. Crowder
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Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase
err2024-05-10
err0
errOAAI
errCheng, Zishuo; Aitha, Mahesh; Thomas, Caitlyn A.; Sturgill, Aidan; Fairweather, Mitch; Hu, Amy; Bethel, Christopher R.; Rivera, Dann D.; Dranchak, Patricia; Thomas, Pei W.; Li, Han; Feng, Qi; Tao, Kaicheng; Song, Minshuai; Sun, Na; Wang, Shuo; Silwal, Surendra Bikram; Page, Richard C.; Fast, Walt; Bonomo, Robert A.; Weese, Maria; Martinez, Waldyn; Inglese, James; Crowder, Michael W.
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The directed evolution of NDM-1NDM-1的定向进化
err2023-11-15
err1
errOAAI
errThomas, Caitlyn A.; Cheng, Zishuo; Bethel, Christopher R.; Hujer, Andrea M.; Sturgill, Aidan M.; Onuoha, Kelechi; Page, Richard C.; Bonomo, Robert A.; Crowder, Michael W.; Tamma, Pranita D.
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Targeting Mitochondrial Sirtuins in Age-Related Neurodegenerative Diseases and Fibrosis在年龄相关的神经退行性疾病和纤维化中靶向线粒体Sirtuins
err2023-01-01
err7
errOAAI
errXiao, Haoxiang; Xie, Yuqiao; Xi, Kaiwen; Xie, Jinyi; Liu, Mingyue; Zhang, Yangming; Cheng, Zishuo; Wang, Wenting; Guo, Baolin; Wu, Shengxi
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Spectroscopic and biochemical characterization of metallo-8-lactamase IMP-1 with dicarboxylic, sulfonyl, and thiol inhibitors
err2021-06-01
err5
errOAAI
errZhang, Huan; Yang, Kundi; Cheng, Zishuo; Thomas, Caitlyn; Steinbrunner, Abbie; Pryor, Cecily; Vulcan, Maya; Kemp, Claire; Orea, Diego; Paththamperuma, Chathura; Chen, Allie Y.; Cohen, Seth M.; Page, Richard C.; Tierney, David L.; Crowder, Michael W.
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Visualizing the Dynamic Metalation State of New Delhi Metallo-β-actamase-1 in Bacteria Using a Reversible Fluorescent Probe
err2021-05-26
err21
errOAAI
errMehta, Radhika; Rivera, Dann D.; Reilley, David J.; Tan, Dominique; Thomas, Pei W.; Hinojosa, Abigail; Stewart, Alesha C.; Cheng, Zishuo; Thomas, Caitlyn A.; Crowder, Michael W.; Alexandrova, Anastassia N.; Fast, Walter; Que, Emily L.
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Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants
err2021-03-18
err17
errOAAI
errCheng, Zishuo; Bethel, Christopher R.; Thomas, Pei W.; Shurina, Ben A.; Alao, John-Paul; Thomas, Caitlyn A.; Yang, Kundi; Marshall, Steven H.; Zhang, Huan; Sturgill, Aidan M.; Kravats, Andrea N.; Page, Richard C.; Fast, Walter; Bonomo, Robert A.; Crowder, Michael W.
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Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1
err2020-09-01
err20
PREAI
errThomas, Caitlyn A.; Cheng, Zishuo; Yang, Kundi; Hellwarth, Elle; Yurkiewicz, Cole J.; Baxter, Faith M.; Fullington, Sarah A.; Klinsky, Spencer A.; Otto, Jen L.; Chen, Allie Y.; Cohen, Seth M.; Crowder, Michael W.
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Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development
err2020-05-07
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errOAAI
errChen, Allie Y.; Thomas, Caitlyn A.; Thomas, Pei W.; Yang Kundi; Cheng Zishuo; Fast, Walter; Crowder, Michael W.; Cohen, Seth M.
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Elusive structural changes of New Delhi metallo-β-lactamase revealed by ultraviolet photodissociation mass spectrometry
err2020-01-01
err17
errOAAI
errMehaffey, M. Rachel; Ahn, Yeong-Chan; Rivera, Dann D.; Thomas, Pei W.; Cheng, Zishuo; Crowder, Michael W.; Pratt, R. F.; Fast, Walter; Brodbelt, Jennifer S.
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A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions
errMBIO
IF4.7
err2019-12-24
err18
errOAAI
errCheng, Zishuo; Shurina, Ben A.; Bethel, Christopher R.; Thomas, Pei W.; Marshall, Steven H.; Thomas, Caitlyn A.; Yang, Kundi; Kimble, Robert L.; Montgomery, Jonathan S.; Orischak, Matthew G.; Miller, Callie M.; Tennenbaum, Jordan L.; Nix, Jay C.; Tierney, David L.; Fast, Walter; Bonomo, Robert A.; Page, Richard C.; Crowder, Michael W.
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Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-β-Lactamases
err2019-05-24
err29
errOAAI
errChen, Allie Y.; Thomas, Pei W.; Cheng, Zishuo; Xu, Nasa Y.; Tierney, David L.; Crowder, Michael W.; Fast, Walter; Cohen, Seth M.
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Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity
err2018-08-01
err85
errOAAI
errCheng, Zishuo; Thomas, Pei W.; Ju, Lincheng; Bergstrom, Alexander; Mason, Kelly; Clayton, Delaney; Miller, Callie; Bethel, Christopher R.; VanPelt, Jamie; Tierney, David L.; Page, Richard C.; Bonomo, Robert A.; Fast, Walter; Crowder, Michael W.
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Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1
err2018-07-18
err2
errOAAI
errChen, Allie Y.; Thomas, Pei W.; Stewart, Alesha C.; Bergstrom, Alexander; Cheng, Zishuo; Miller, Callie; Bethel, Christopher R.; Marshall, Steven H.; Credille, Cy V.; Riley, Christopher L.; Page, Richard C.; Bonomo, Robert A.; Crowder, Michael W.; Tierney, David L.; Fast, Walter; Cohen, Seth M.
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The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters
err2018-07-01
err118
errOAAI
errJu, Lin-Cheng; Cheng, Zishuo; Fast, Walter; Bonomo, Robert A.; Crowder, Michael W.
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Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7
err2017-11-09
err58
errOAAI
errBergstrom, Alexander; Katko, Andrew; Adkins, Zach; Hill, Jessica; Cheng, Zishuo; Burnett, Mia; Yang, Hao; Aitha, Mahesh; Mehaffey, M. Rachel; Brodbelt, Jennifer S.; Tehrani, Kamaleddin H. M. E.; Martin, Nathaniel I.; Bonomo, Robert A.; Page, Richard C.; Tierney, David L.; Fast, Walter; Wright, Gerard D.; Crowder, Michael W.
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Clinical Variants of New Delhi Metallo-β-Lactannase Are Evolving To Overcome Zinc Scarcity
err2017-10-11
err53
errOAAI
errStewart, Alesha C.; Bethel, Christopher R.; VanPelt, Jamie; Bergstrom, Alex; Cheng, Zishuo; Miller, Callie G.; Williams, Cameron; Poth, Robert; Morris, Matthew; Lahey, Olivia; Nix, Jay C.; Tierney, David L.; Page, Richard C.; Crowder, Michael W.; Bonomo, Robert A.; Fast, Walter
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