未登录 RAC1 regulates Sonic Hedgehog-medulloblastoma growth via GLI-mediated transcription RAC1通过GLI介导的转录调节Sonic Hedgehog髓母细胞瘤生长 Jangde, Nitish; Lee, Mi-Hye; Ruiz, Luz; Egan, Isabelle; Jermakowicz, Anna M.; Chowdary, Rishika; Chu, Jonathan; Wynn, Daniel T.; Goka, Erik; Lippman, Marc; Robbins, David J.; Ayad, Nagi G. 分享 收藏
Wnt signaling inhibits casein kinase 1a activity by modulating its interaction with protein phosphatase 2A Wnt信号通过调节其与蛋白磷酸酶2A的相互作用来抑制酪蛋白激酶1a的活性。 Shen, Chen; Lu, Wenhui; Merugu, Siva B.; Bharti, Aradhana; Afify, Said M.; Schnitkey, Lauren; Wynn, Daniel T.; Yang, Fan; Rohwetter, Thomas M.; Nayak, Anmada; Bunnag, Nawat; Cywiak, Carolina; Tang, Hsin-Yao; Harris, Brent T.; Albanese, Christopher; Ihemelandu, Chukwuemeka; Cobb, Melanie H.; Kettenbach, Arminja; Lee, Ethan; Ahmed, Yashi; Robbins, David J. 分享 收藏
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Enhancing precision in colorectal cancer surgery: development of an LGR5-targeting RSPO1 peptide mimetic as a contrast agent for intraoperative fluorescence molecular imaging Parasido, Erika; Ribeiro, Patricia; Chingle, Ramesh M.; Rohwetter, Thomas; Gupta, Nikita; Avetian, George; Bladelli, Elisa; Pierobon, Mariaelena; Chen, Yu; Tang, Qinggong; Schnermann, Martin; Rodriguez, Olga; Robbins, David; Burke Jr, Terrence R.; Albanese, Chris; Ihemelandu, Chukwuemeka 分享 收藏
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Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models Rodriguez-Blanco, Jezabel; Salvador, April D.; Suter, Robert K.; Swiderska-Syn, Marzena; Palomo-Caturla, Isabel; Kliebe, Valentin; Shahani, Pritika; Peterson, Kendell; Turos-Cabal, Maria; Vieira, Megan E.; Wynn, Daniel T.; Howell, Ashley J.; Yang, Fan; Ban, Yuguang; McCrea, Heather J.; Zindy, Frederique; Danis, Etienne; Vibhakar, Rajeev; Jermakowicz, Anna; Martin, Vanesa; Coss, Christopher C.; Harris, Brent T.; de Cubas, Aguirre; Chen, X. Steven; Barnoud, Thibaut; Roussel, Martine F.; Ayad, Nagi G.; Robbins, David J. 分享 收藏
Rectal implantation paves the path to evaluate the metabolic machinery responsible for CRC metastasis Afify, Said M.; Shen, Chen; Merugu, Siva B.; Wynn, Daniel T.; Nayak, Anmada; Lu, Wenhui; Calderin, Ricardo M.; Pannkuk, Evan; Hong, Sung H.; Ayad, Nagi G.; Robbins, David J. 分享 收藏
The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6 Spencer, Zachary T.; Ng, Victoria H.; Benchabane, Hassina; Siddiqui, Ghalia Saad; Duwadi, Deepesh; Maines, Ben; Bryant, Jamal M.; Schwarzkopf, Anna; Yuan, Kai; Kassel, Sara N.; Mishra, Anant; Pimentel, Ashley; Lebensohn, Andres M.; Rohatgi, Rajat; Gerber, Scott A.; Robbins, David J.; Lee, Ethan; Ahmed, Yashi 分享 收藏
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USP47 deubiquitylates Groucho/TLE to promote Wnt-?-catenin signaling Kassel, Sara; Hanson, Alison J.; Benchabane, Hassina; Saito-Diaz, Kenyi; Cabel, Carly R.; Goldsmith, Lily; Taha, Muhammad; Kanuganti, Aksheta; Ng, Victoria H.; Xu, George; Ye, Fei; Picker, Julia; Port, Fillip; Boutros, Michael; Weiss, Vivian L.; Robbins, David J.; Thorne, Curtis A.; Ahmed, Yashi; Lee, Ethan 分享 收藏
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A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth Yang, Fan; Rodriguez-Blanco, Jezabel; Long, Jun; Swiderska-Syn, Marzena; Wynn, Daniel T.; Li, Bin; Shen, Chen; Nayak, Anmada; Ban, Yuguang; Sun, Xiaodian; Suter, Robert K.; McCrea, Heather J.; Capobianco, Anthony J.; Ayad, Nagi G.; Robbins, David J. 分享 收藏
The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon Shen, Chen; Nayak, Anmada; Neitzel, Leif R.; Yang, Fan; Li, Bin; Williams, Charles H.; Hong, Charles C.; Ahmed, Yashi; Lee, Ethan; Robbins, David J. 分享 收藏
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