Kevin D. Raney - Publications, H-index & Citations

Kevin D. Raney

university of arkansas for medical sciences

43H指数

132论文数

4.6K被引数

收录论文 57

发表时间

The nucleoside analog CMX521 inhibits coronavirus RNA-dependent RNA polymerase via a two-pronged mechanism 核苷类似物CMX521通过双机制抑制冠状病毒RNA依赖性RNA聚合酶

Journal of Biological Chemistry

IF3.9

2026-09-16

OAAI

Asif Rakib; Calvin J. Gordon; Thomas K. Anderson; John C. Marecki; Quinte Smitskamp; Nathaniel J. Moorman; Mark T. Heise; Heidi M. Colton; Dean Selleseth; Randall Lanier; Kevin D. Raney; Robert N. Kirchdoerfer; Matthias Götte; David Dulin

Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir 冠状病毒聚合酶介导的复制回环RNA合成需要解旋酶活性，并受到瑞德西韦和莫诺拉韦的刺激

Science Advances

IF12.5

2026-06-19

OAAI

Asif Rakib; Arnab Das; Subhas C. Bera; Jelmer Cnossen; Refugio Robles-Sikisaka; Meghan V. Diefenbacher; Pim P. B. America; Misha Klein; Thomas K. Anderson; John C. Marecki; Bing Wang; Eline Bogers; Joy Y. Feng; John P. Bilello; Flávia S. Papini; Quinte Smitskamp; Timothy P. Sheahan; Jamie J. Arnold; Andrew Routh; Irina Artsimovitch; Robert N. Kirchdoerfer; Craig E. Cameron; Kevin D. Raney; David Dulin

RNA virus polymerase-helicase coupling enables rapid elongation through duplex RNA RNA病毒聚合酶-解旋酶偶联通过双链RNA实现快速延伸

Cell Reports

IF6.9

2026-04-16

OAAI

Pim P.B. America; Subhas C. Bera; Arnab Das; Thomas K. Anderson; John C. Marecki; Flávia S. Papini; Jamie J. Arnold; Robert N. Kirchdoerfer; Craig E. Cameron; Kevin D. Raney; Martin Depken; David Dulin

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent 组装后的构象变化使SARS-CoV-2聚合酶获得延伸活性。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-06-10

PREAI

Klein, Misha; Das, Arnab; Bera, Subhas C.; Anderson, Thomas K.; Kocincova, Dana; Lee, Hery W.; Wang, Bing; Papini, Flavia S.; Marecki, John C.; Arnold, Jamie J.; Cameron, Craig E.; Raney, Kevin D.; Artsimovitch, Irina; Gotte, Mathias; Kirchdoerfer, Robert N.; Depken, Martin; Dulin, David

Autophosphorylation of the Tousled-like kinases TLK1 and TLK2 regulates recruitment to damaged chromatin via PCNA interaction

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-27

OAAI

West, Kirk L.; Nguyen, Tram T. N.; Tengler, Kyle A.; Kreiling, Natasha; Raney, Kevin D.; Ghosal, Gargi; Leung, Justin W.

Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge

NATURE COMMUNICATIONS

IF15.7

2024-07-19

OAAI

Hong, Zebin; Byrd, Alicia K.; Gao, Jun; Das, Poulomi; Tan, Vanessa Qianmin; Malone, Emory G.; Osei, Bertha; Marecki, John C.; Protacio, Reine U.; Wahls, Wayne P.; Raney, Kevin D.; Song, Haiwei

Two residues in the DNA binding site of Pif1 helicase are essential for nuclear functions but dispensable for mitochondrial respiratory growth

NUCLEIC ACIDS RESEARCH

IF13.1

2024-05-16

OAAI

Gao, Jun; Proffitt, David R.; Marecki, John C.; Protacio, Reine U.; Wahls, Wayne P.; Byrd, Alicia K.; Raney, Kevin D.

Hepatitis C virus nonstructural protein NS3 unfolds viral G-quadruplex RNA structures

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-11-01

OAAI

Belachew, Binyam; Gao, Jun; Byrd, Alicia K.; Raney, Kevin D.

Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-06-01

OAAI

Delgado, Magdalena; Rainwater, Randall R.; Heflin, Billie; Urbaniak, Alicja; Butler, Kaitlynn; Davidson, Mari; Protacio, Reine M.; Baldini, Giulia; Edwards, Andrea; Reed, Megan R.; Raney, Kevin D.; Chambers, Timothy C.

G-quadruplex DNA inhibits unwinding activity but promotes liquid-liquid phase separation by the DEAD-box helicase Ded1p G-四链体DNA抑制解旋活性，但通过死盒解旋酶Ded1p促进液-液相分离

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-01

OAAI

Gao, Jun; Gao, Zhaofeng; Putnam, Andrea A.; Byrd, Alicia K.; Venus, Sarah L.; Marecki, John C.; Edwards, Andrea D.; Lowe, Haley M.; Jankowsky, Eckhard; Raney, Kevin D.

G-Quadruplex loops regulate PARP-1 enzymatic activation

NUCLEIC ACIDS RESEARCH

IF13.1

2020-12-11

OAAI

Edwards, Andrea D.; Marecki, John C.; Byrd, Alicia K.; Gao, Jun; Raney, Kevin D.

Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro

HUMAN MOLECULAR GENETICS

IF3.2

2020-03-19

OAAI

Butler, Thomas J.; Estep, Katrina N.; Sommers, Joshua A.; Maul, Robert W.; Moore, Ann Zenobia; Bandinelli, Stefania; Cucca, Francesco; Tuke, Marcus A.; Wood, Andrew R.; Bharti, Sanjay Kumar; Bogenhagen, Daniel F.; Yakubovskaya, Elena; Garcia-Diaz, Miguel; Guilliam, Thomas A.; Byrd, Alicia K.; Raney, Kevin D.; Doherty, Aidan J.; Ferrucci, Luigi; Schlessinger, David; Ding, Jun; Brosh, Robert M., Jr.

Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles 复制障碍解释了DNA合成过程中正确核苷酸的过度切除

EMBO JOURNAL

IF8.3

2020-02-09

OAAI

Singh, Anupam; Pandey, Manjula; Nandakumar, Divya; Raney, Kevin D.; Yin, Y. Whitney; Patel, Smita S.

Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases

NATURE COMMUNICATIONS

IF15.7

2019-11-26

OAAI

Su, Nannan; Byrd, Alicia K.; Bharath, Sakshibeedu R.; Yang, Olivia; Jia, Yu; Tang, Xuhua; Ha, Taekjip; Raney, Kevin D.; Song, Haiwei

Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase

NUCLEIC ACIDS RESEARCH

IF13.1

2019-06-19

OAAI

Lu, Chen; Le, Shimin; Chen, Jin; Byrd, Alicia K.; Rhodes, Daniela; Raney, Kevin D.; Yan, Jie

DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA

CHEMICAL COMMUNICATIONS

IF4.2

2019-01-01

OAAI

Gao, Jun; Byrd, Alicia K.; Zybailov, Boris L.; Marecki, John C.; Guderyon, Michael J.; Edwards, Andrea D.; Chib, Shubeena; West, Kirk L.; Waldrip, Zachary J.; Mackintosh, Samuel G.; Gao, Zhaofeng; Putnam, Andrea A.; Jankowsky, Eckhard; Raney, Kevin D.

Pif1 helicase unfolding of G-quadruplex DNA is highly dependent on sequence and reaction conditions G-四链体DNA的Pif1解旋酶解折叠高度依赖于序列和反应条件

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-11-01

OAAI

Byrd, Alicia K.; Bell, Matthew R.; Raney, Kevin D.

When Helicase and Polymerases Collides and Unfolds G4-Quadruplex on their Track

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Croquette, Vincent; Hodeib, Samar; Boule, Jean-Baptiste; Chib, Shubeena; Raney, Kevin D.