未登录Cholesterol reduction by immunization with a PCSK9 mimic
Zhang, Baoshan; Chuang, Gwo-Yu; Biju, Andrea; Biner, Daniel; Cheng, Jiaxuan; Wang, Yiran; Bao, Saran; Chao, Cara W.; Lei, Haotian; Liu, Tracy; Nazzari, Alexandra F.; Yang, Yongping; Zhou, Tongqing; Chen, Steven J.; Chen, Xuejun; Kong, Wing-Pui; Ou, Li; Parchment, Danealle K.; Sarfo, Edward K.; Sima, Haomin; Todd, John -Paul; Wang, Shuishu; Woodward, Ruth A.; Cheng, Cheng; Rawi, Reda; Mascola, John R.; Kwong, Peter D. .png)
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收藏分享 收藏 Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide siteBanach, Bailey B.; Pletnev, Sergei; Olia, Adam S.; Xu, Kai; Zhang, Baoshan; Rawi, Reda; Bylund, Tatsiana; Doria-Rose, Nicole A.; Nguyen, Thuy Duong; Fahad, Ahmed S.; Lee, Myungjin; Lin, Bob C.; Liu, Tracy; Louder, Mark K.; Madan, Bharat; Mckee, Krisha; O'Dell, Sijy; Sastry, Mallika; Schoen, Arne; Bui, Natalie; Shen, Chen-Hsiang; Wolfe, Jacy R.; Chuang, Gwo-Yu; Mascola, John R.; Kwong, Peter D.; Dekosky, Brandon J. 分享 收藏 An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challengeFreyn, Alec W.; Atyeo, Caroline; Earl, Patricia L.; Americo, Jeffrey L.; Chuang, Gwo-Yu; Natarajan, Harini; Frey, Tiffany R.; Gall, Jason G.; Moliva, Juan I.; Hunegnaw, Ruth; Arunkumar, Guha Asthagiri; Ogega, Clinton O.; Nasir, Arshan; Santos, Genesis; Levin, Rafael H.; Meni, Anusha; Jorquera, Patricia A.; Bennett, Hamilton; Johnson, Joshua A.; Durney, Michael A.; Stewart-Jones, Guillaume; Hooper, Jay W.; Colpitts, Tonya M.; Alter, Galit; Sullivan, Nancy J.; Carfi, Andrea; Moss, Bernard 分享 收藏 Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV NeutralizationSastry, Mallika; Changela, Anita; Gorman, Jason; Xu, Kai; Chuang, Gwo-Yu; Shen, Chen-Hsiang; Cheng, Cheng; Geng, Hui; O'Dell, Sijy; Ou, Li; Rawi, Reda; Reveiz, Mateo; Stewart-Jones, Guillaume B. E.; Wang, Shuishu; Zhang, Baoshan; Zhou, Tongqing; Biju, Andrea; Chambers, Michael; Chen, Xuejun; Corrigan, Angela R.; Lin, Bob C.; Louder, Mark K.; McKee, Krisha; Nazzari, Alexandra F.; Olia, Adam S.; Parchment, Danealle K.; Sarfo, Edward K.; Stephens, Tyler; Stuckey, Jonathan; Tsybovsky, Yaroslav; Verardi, Raffaello; Wang, Yiran; Zheng, Cheng-Yan; Chen, Yuling; Doria-Rose, Nicole A.; McDermott, Adrian B.; Mascola, John R.; Kwong, Peter D. 分享 收藏 Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in miceScheaffer, Suzanne M.; Lee, Diana; Whitener, Bradley; Ying, Baoling; Wu, Kai; Liang, Chieh-Yu; Jani, Hardik; Martin, Philippa; Amato, Nicholas J.; Avena, Laura E.; Berrueta, Daniela Montes; Schmidt, Stephen D.; O'Dell, Sijy; Nasir, Arshan; Chuang, Gwo-Yu; Stewart-Jones, Guillaume; Koup, Richard A.; Doria-Rose, Nicole A.; Carfi, Andrea; Elbashir, Sayda M.; Thackray, Larissa B.; Edwards, Darin K.; Diamond, Michael S. 分享 收藏 分享 收藏 Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2Cale, Evan M.; Driscoll, Jefferson, I; Lee, Myungjin; Gorman, Jason; Zhou, Tongqing; Lu, Maolin; Geng, Hui; Lai, Yen-Ting; Chuang, Gwo-Yu; Doria-Rose, Nicole A.; Mothes, Walther; Kwong, Peter D.; Mascola, John R. 分享 收藏 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodiesKratochvil, Sven; Shen, Chen-Hsiang; Lin, Ying-Cing; Xu, Kai; Nair, Usha; Pereira, Lais Da Silva; Tripathi, Prabhanshu; Arnold, Johan; Chuang, Gwo-Yu; Melzi, Eleonora; Schon, Arne; Zhang, Baoshan; Dillon, Marlon; Bonilla, Brian; Flynn, Barbara J.; Kirsch, Kathrin H.; Kisalu, Neville K.; Kiyuka, Patience K.; Liu, Tracy; Ou, Li; Pancera, Marie; Rawi, Reda; Reveiz, Mateo; Seignon, Kareen; Wang, Lawrence T.; Waring, Michael T.; Warner, John; Yang, Yongping; Francica, Joseph R.; Idris, Azza H.; Seder, Robert A.; Kwong, Peter D.; Batista, Facundo D. 分享 收藏 Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfacesLee, Myungjin; Changela, Anita; Gorman, Jason; Rawi, Reda; Bylund, Tatsiana; Chao, Cara W.; Lin, Bob C.; Louder, Mark K.; Olia, Adam S.; Zhang, Baoshan; Doria-Rose, Nicole A.; Zolla-Pazner, Susan; Shapiro, Lawrence; Chuang, Gwo-Yu; Kwong, Peter D. 分享 收藏 Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodiesCottrell, Christopher A.; Manne, Kartik; Kong, Rui; Wang, Shuishu; Zhou, Tongqing; Chuang, Gwo-Yu; Edwards, Robert J.; Henderson, Rory; Janowska, Katarzyna; Kopp, Megan; Lin, Bob C.; Louder, Mark K.; Olia, Adam S.; Rawi, Reda; Shen, Chen-Hsiang; Taft, Justin D.; Torres, Jonathan L.; Wu, Nelson R.; Zhang, Baoshan; Doria-Rose, Nicole A.; Cohen, Myron S.; Haynes, Barton F.; Shapiro, Lawrence; Ward, Andrew B.; Acharya, Priyamvada; Mascola, John R.; Kwong, Peter D. 分享 收藏 Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responsesStewart-Jones, Guillaume B. E.; Gorman, Jason; Ou, Li; Zhang, Baoshan; Joyce, M. Gordon; Yang, Lijuan; Cheng, Cheng; Chuang, Gwo-Yu; Foulds, Kathryn E.; Kong, Wing-Pui; Olia, Adam S.; Sastry, Mallika; Shen, Chen-Hsiang; Todd, John-Paul; Tsybovsky, Yaroslav; Verardi, Raffaello; Yang, Yongping; Collins, Peter L.; Corti, Davide; Lanzavecchia, Antonio; Scorpio, Diana G.; Mascola, John R.; Buchholz, Ursula J.; Kwong, Peter D. 分享 收藏 Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodiesFrank, Ines; Cigoli, Mariasole; Arif, Muhammad S.; Fahlberg, Marissa D.; Maldonado, Stephanie; Calenda, Giulia; Pegu, Amarendra; Yang, Eun Sung; Rawi, Reda; Chuang, Gwo-Yu; Geng, Hui; Liu, Cuiping; Zhou, Tongqing; Kwong, Peter D.; Arthos, James; Cicala, Claudia; Grasperge, Brooke F.; Blanchard, James L.; Gettie, Agegnehu; Fennessey, Christine M.; Keele, Brandon F.; Vaccari, Monica; Hope, Thomas J.; Fauci, Anthony S.; Mascola, John R.; Martinelli, Elena 分享 收藏 Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINsXu, Kai; Wang, Yiran; Shen, Chen-Hsiang; Chen, Yiwei; Zhang, Baoshan; Liu, Kevin; Tsybovsky, Yaroslav; Wang, Shuishu; Farney, S. Katie; Gorman, Jason; Stephens, Tyler; Verardi, Raffaello; Yang, Yongping; Zhou, Tongqing; Chuang, Gwo-Yu; Lanzavecchia, Antonio; Piccoli, Luca; Kwong, Peter D. 分享 收藏 Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A VirusesChuang, Gwo-Yu; Shen, Chen-Hsiang; Cheung, Crystal Sao-Fong; Gorman, Jason; Creanga, Adrian; Joyce, M. Gordon; Leung, Kwanyee; Rawi, Reda; Wang, Lingshu; Yang, Eun Sung; Yang, Yongping; Zhang, Baoshan; Zhang, Yi; Kanekiyo, Masaru; Zhou, Tongqing; DeKosky, Brandon J.; Graham, Barney S.; Mascola, John R.; Kwong, Peter D. 分享 收藏 Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria设计呈现环子孢子连接表位的甲病毒病毒样颗粒，以引起对疟疾的保护Francica, Joseph R.; Shi, Wei; Chuang, Gwo-Yu; Chen, Steven J.; Da Silva Pereira, Lais; Farney, S. Katie; Flynn, Barbara J.; Ou, Li; Stephens, Tyler; Tsybovsky, Yaroslav; Wang, Lawrence T.; Anderson, Alexander; Beck, Zoltan; Dillon, Marlon; Idris, Azza H.; Hurlburt, Nicholas; Liu, Tracy; Zhang, Baoshan; Alving, Carl R.; Matyas, Gary R.; Pancera, Marie; Mascola, John R.; Kwong, Peter D.; Seder, Robert A. 分享 收藏 Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody突变适应性景观揭示了疫苗引发的HIV-1广泛中和抗体的遗传和结构改善途径Madan, Bharat; Zhang, Baoshan; Xu, Kai; Chao, Cara W.; O'Dell, Sijy; Wolfe, Jacy R.; Chuang, Gwo-Yu; Fahad, Ahmed S.; Geng, Hui; Kong, Rui; Louder, Mark K.; Thuy Duong Nguyen; Rawi, Reda; Schon, Arne; Sheng, Zizhang; Nimrania, Rajani; Wang, Yiran; Zhou, Tongqing; Lin, Bob C.; Doria-Rose, Nicole A.; Shapiro, Lawrence; Kwong, Peter D.; DeKosky, Brandon J. 分享 收藏 Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadthChen, Xuejun; Zhou, Tongqing; Schmidt, Stephen D.; Duan, Hongying; Cheng, Cheng; Chuang, Gwo-Yu; Gu, Ying; Louder, Mark K.; Lin, Bob C.; Shen, Chen-Hsiang; Sheng, Zizhang; Zheng, Michelle X.; Doria-Rose, Nicole A.; Joyce, M. Gordon; Shapiro, Lawrence; Tian, Ming; Alt, Frederick W.; Kwong, Peter D.; Mascola, John R. 分享 收藏 Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses显示融合前稳定的SARS-CoV-2尖峰的新城疫病毒样颗粒引起有效的中和反应Yang, Yongping; Shi, Wei; Abiona, Olubukola M.; Nazzari, Alexandra; Olia, Adam S.; Ou, Li; Phung, Emily; Stephens, Tyler; Tsybovsky, Yaroslav; Verardi, Raffaello; Wang, Shuishu; Werner, Anne; Yap, Christina; Ambrozak, David; Bylund, Tatsiana; Liu, Tracy; Nguyen, Richard; Wang, Lingshu; Zhang, Baoshan; Zhou, Tongqing; Chuang, Gwo-Yu; Graham, Barney S.; Mascola, John R.; Corbett, Kizzmekia S.; Kwong, Peter D. 分享 收藏 Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopesVerardi, Raffaello; Lindesmith, Lisa C.; Tsybovsky, Yaroslav; Gorman, Jason; Chuang, Gwo-Yu; Edwards, Caitlin E.; Brewer-Jensen, Paul D.; Mallory, Michael L.; Ou, Li; Schon, Arne; Shi, Wei; Tully, Ena S.; Georgiou, George; Baric, Ralph S.; Kwong, Peter D. 分享 收藏 
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