Leo A. Joyce - Publications, H-index & Citations

Leo A. Joyce

merck & company

30H指数

86论文数

3.5K被引数

收录论文 35

发表时间

Strategies for the Evaluation and Characterization of Higher-Order Structures, Supramolecular Higher-Order Structures, and Aggregates in Oligonucleotide Therapeutics 寡核苷酸治疗药物中高阶结构、超分子高阶结构和聚集体的评估与表征策略

Journal of Pharmaceutical Sciences

IF3.8

2025-06-22

PREAI

Laure-Elie Carloni; George Bou-Assaf; Arani Chanda; Lingwen Cui; Ahmed Elmekawy; Maryam Farzan; Leo Joyce; Ranajoy Majumdar; Zahid Nazir; Ulrike Rieder; Eric Shi; Haiqing Yin; Yueheng Zhang

Racemic Synthesis of a Key 1,4-Dihydro-2H-spiro[isoquinoline-3,4′- piperidin]-3′-ol Building Block

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2022-11-08

PREAI

Candito, David A.; Martinot, Theodore A.; Su, Jing; Sauri, Josep; Lam, Yu-hong; Joyce, Leo A.; Silverman, Steven M.; Sloman, David L.; Maddess, Matthew L.; Macha, Michelle R.

Synthesis of a novel cyclopropyl phosphonate nucleotide as a phosphate mimic

CHEMICAL COMMUNICATIONS

IF4.2

2021-01-01

PREAI

Altenhofer, Erich F.; Lawler, Michael J.; Kumar, Pankaj; Joyce, Leo A.; Fowler-Watters, Matthew; Pei, Tao; Li, Zhen

A chiroptical approach for the absolute stereochemical determination of P-stereogenic centers

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Chakraborty, Debarshi; Gholami, Hadi; Sarkar, Aritra; Joyce, Leo A.; Jackson, James E.; Borhan, Babak

Next-Generation TLC: A Quantitative Platform for Parallel Spotting and Imaging

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2020-06-19

OAAI

Boulgakov, Alexander A.; Moor, Sarah R.; Jo, Hyun Hwa; Metola, Pedro; Joyce, Leo A.; Marcotte, Edward M.; Welch, Christopher J.; Anslyn, Eric, V

The Structural Origins of Intense Circular Dichroism in a Waggling Helicene Nanoribbon

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-04-03

OAAI

Schuster, Nathaniel J.; Joyce, Leo A.; Paley, Daniel W.; Ng, Fay; Steigerwald, Michael L.; Nuckolls, Colin

Combination of HDX-MS and in silico modeling to study enzymatic reactivity and stereo-selectivity at different solvent conditions

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2020-04-01

PREAI

Makarov, Alexey A.; Iacob, Roxana E.; Pirrone, Gregory F.; Rodriguez-Granillo, Agustina; Joyce, Leo; Mangion, Ian; Moore, Jeffrey C.; Sherer, Edward C.; Engen, John R.

C-C Cleavage Approach to C-H Functionalization of Saturated Aza-Cycles

ACS CATALYSIS

IF13.1

2020-01-16

OAAI

Roque, Jose B.; Kuroda, Yusuke; Jurczyk, Justin; Xu, Li-Ping; Ham, Jin Su; Gottemann, Lucas T.; Roberts, Charis A.; Adpressa, Donovon; Sauri, Josep; Joyce, Leo A.; Musaev, Djamaladdin G.; Yeung, Charles S.; Sarpong, Richmond

Direct regioisomer analysis of crude reaction mixtures via molecular rotational resonance (MRR) spectroscopy

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Joyce, Leo A.; Schultz, Danielle M.; Sherer, Edward C.; Neill, Justin L.; Sonstrom, Reilly E.; Pate, Brooks H.

Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-11-06

OAAI

Pyser, Joshua B.; Dockrey, Summer A. Baker; Benitez, Attabey Rodriguez; Joyce, Leo A.; Wiscons, Ren A.; Smith, Janet L.; Narayan, Alison R. H.

Manipulating Solid Forms of Contact Insecticides for Infectious Disease Prevention

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-10-11

PREAI

Zhu, Xiaolong; Hu, Chunhua T.; Yang, Jingxiang; Joyce, Leo A.; Qiu, Mengdi; Ward, Michael D.; Kahr, Bart

Rhodium-Catalyzed Asymmetric Hydroamination of Allyl Amines 铑催化烯丙基胺的不对称氢胺化反应

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-01-07

OAAI

Vanable, Evan P.; Kennemur, Jennifer L.; Joyce, Leo A.; Ruck, Rebecca T.; Schultz, Danielle M.; Hull, Kami L.

Optical Analysis of Reaction Yield and Enantiomeric Excess: A New Paradigm Ready for Prime Time

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2018-07-30

132

PREAI

Herrera, Brenden T.; Pilicer, Samantha L.; Anslyn, Eric V.; Joyce, Leo A.; Wolf, Christian

Optical Chirality Sensing with a Stereodynamic Aluminum Biphenolate Probe

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2018-07-18

PREAI

De los Santos, Zeus A.; Joyce, Leo A.; Sherer, Edward C.; Welch, Christopher J.; Wolf, Christian

Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2018-02-27

PREAI

Blincoe, William D.; Rodriguez-Granillo, Agustina; Sauri, Josep; Pierson, Nicholas A.; Joyce, Leo A.; Mangion, Ian; Sheng, Huaming

Beyond optical rotation: what's left is not always right in total synthesis

CHEMICAL SCIENCE

IF7.4

2018-01-01

OAAI

Joyce, Leo A.; Nawrat, Christopher C.; Sherer, Edward C.; Biba, Mirlinda; Brunskill, Andrew; Martin, Gary E.; Cohen, Ryan D.; Davies, Ian W.

Oxyfunctionalization of the Remote C-H Bonds of Aliphatic Amines by Decatungstate Photocatalysis

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2017-10-26

119

PREAI

Schultz, Danielle M.; Levesque, Francois; DiRocco, Daniel A.; Reibarkh, Mikhail; Ji, Yining; Joyce, Leo A.; Dropinski, James F.; Sheng, Huaming; Sherry, Benjamin D.; Davies, Ian W.

Parameterization of Acyclic Diaminocarbene Ligands Applied to a Gold(I)-Catalyzed Enantioselective Tandem Rearrangement/Cyclization

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2017-09-08

OAAI

Niemeyer, Zachary L.; Pindi, Suresh; Khrakovsky, Dimitri A.; Kuzniewski, Christian N.; Hong, Cynthia M.; Joyce, Leo A.; Sigman, Matthew S.; Toste, F. Dean

Palladium-catalyzed enantioselective Heck alkenylation of trisubstituted allylic alkenols: a redox-relay strategy to construct vicinal stereocenters

CHEMICAL SCIENCE

IF7.4

2017-01-01

OAAI

Zhang, Chun; Tutkowski, Brandon; DeLuca, Ryan J.; Joyce, Leo A.; Wiest, Olaf; Sigman, Matthew S.

Ultrafast chiral separations for high throughput enantiopurity analysis

CHEMICAL COMMUNICATIONS

IF4.2

2017-01-01

129

PREAI

Barhate, Chandan L.; Joyce, Leo A.; Makarov, Alexey A.; Zawatzky, Kerstin; Bernardoni, Frank; Schafer, Wes A.; Armstrong, Daniel W.; Welch, Christopher J.; Regalado, Erik L.

研究方向