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W

Willeke van Roon‐Mom

Leiden University

44H指数
184论文数
6.8K被引数
收录论文 17
发表时间
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A simplified and reproducible protocol for percutaneous lumbar intrathecal injection in rats一种简化且可重复的经皮腰椎硬膜内注射大鼠的操作规程
errJournal of Neuroscience Methods
IF2.3
err2026-09-08
err0
errOAAI
errRaul Andres-Santamaria; Roan Hofstede; Maarten van de Wal; Annemieke Aartsma-Rus; Willeke van Roon-Mom; Marcel ter Veld
err分享
err收藏
Polyglutamine expansion induced dynamic misfolding of androgen receptor多聚谷氨酰胺扩展诱导雄激素受体的动态错误折叠
errPROTEIN SCIENCE
IF5.2
err2025-05-15
err0
errOAAI
errHeling, Laurens W. H. J.; Sheikhhassani, Vahid; Ng, Julian; van Vliet, Morris; Jimenez-Panizo, Alba; Alegre-Marti, Andrea; Woodard, Jaie; van Roon-Mom, Willeke; Mcewan, Iain J.; Estebanez-Perpina, Eva
err分享
err收藏
A Guide to Chemical Considerations for the Pre-Clinical Development of Oligonucleotides
errNUCLEIC ACID THERAPEUTICS
IF4.7
err2024-12-01
err0
PREAI
errO'Reilly, Daniel; van Roon-Mom, Willeke; Aartsma-Rus, Annemieke
err分享
err收藏
Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis炎症诱导的TRPV4通道加重多发性硬化患者血脑屏障功能障碍
errJOURNAL OF NEUROINFLAMMATION
IF10.1
err2024-03-23
err3
errOAAI
errHansen, Cathrin E.; Kamermans, Alwin; Mol, Kevin; Berve, Kristina; Rodriguez-Mogeda, Carla; Fung, Wing Ka; van het Hof, Bert; Fontijn, Ruud D.; van der Pol, Susanne M. A.; Michalick, Laura; Kuebler, Wolfgang M.; Kenkhuis, Boyd; van Roon-Mom, Willeke; Liedtke, Wolfgang; Engelhardt, Britta; Kooij, Gijs; Witte, Maarten E.; de Vries, Helga E.
err分享
err收藏
Possibilities and limitations of antisense oligonucleotide therapies for the treatment of monogenic disorders
errCOMMUNICATIONS MEDICINE
IF6.3
err2024-01-05
err65
errOAAI
errLauffer, Marlen C.; van Roon-Mom, Willeke; Aartsma-Rus, Annemieke
err分享
err收藏
Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice反义寡核苷酸介导的HTT caspase-6切割位点的破坏可改善YAC128亨廷顿病小鼠的表型
errNEUROBIOLOGY OF DISEASE
IF5.6
err2024-01-01
err2
errOAAI
errKuijper, Elsa C.; Overzier, Maurice; Suidgeest, Ernst; Dzyubachyk, Oleh; Maguin, Cecile; Perot, Jean-Baptiste; Flament, Julien; Ariyurek, Yavuz; Mei, Hailiang; Buijsen, Ronald A. M.; van der Weerd, Louise; van Roon-Mom, Willeke
err分享
err收藏
Consensus Guidelines for the Design and In Vitro Preclinical Efficacy Testing N-of-1 Exon Skipping Antisense Oligonucleotides
errNUCLEIC ACID THERAPEUTICS
IF4.7
err2023-02-01
err28
errOAAI
errAartsma-Rus, Annemieke; Garanto, Alejandro; Van Roon-Mom, Willeke; McConnell, Erin M.; Suslovitch, Victoria; Yan, Winston X.; Watts, Jonathan K.; Yu, Timothy W.
err分享
err收藏
Considerations in the Preclinical Assessment of the Safety of Antisense Oligonucleotides临床前评估反义寡核苷酸安全性的考虑因素
errNUCLEIC ACID THERAPEUTICS
IF4.7
err2023-02-01
err35
errOAAI
errGoyenvalle, Aurelie; Jimenez-Mallebrera, Cecilia; van Roon, Willeke; Sewing, Sabine; Krieg, Arthur M.; Arechavala-Gomeza, Virginia; Andersson, Patrik
err分享
err收藏
THERAPEUTIC EFFECT OF ANTISENSE OLIGONUCLEOTIDE TREATMENT IN YAC128 HUNTINGTON MICE
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errKuijper, Elsa; Overzier, Maurice; Suidgeest, Ernst; Van der Weerd, Louise; Toonen, Lodewijk; Van Roon-Mom, Willeke
err分享
err收藏
EXPLORING THE ENROLL-HD DATASET USING MACHINE LEARNING FOR PERSONALIZED PREDICTIONS
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errOuwerkerk, Jasper; Feleus, Stephanie; van der Zwaan, Kasper F.; Li, Yunlei; Roos, Marco; van Roon-Mom, Willeke; de Bot, Susanne T.; Wolstencroft, Katherine; Mina, Eleni
err分享
err收藏
REDUCED LEVELS OF THE GLUCOSE TRANSPORTER GLUT-1 IN BRAIN STRIATUM AND PERIPHERY REVEALS CLUES TO SPECIFIC PATHOMECHANISMS IN CHILDHOOD-ONSET HUNTINGTON DISEASE
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errPerrone, Federica; Bakels, Hannah; Tramutola, Antonella; Di Nottia, Michela; Abruzzese, Maria Pia; Zoccola, Martina; Carrozzo, Rosalba; de Bot, Susanne; Perluigi, Marzia; van Roon-Mom, Willeke; Squitieri, Ferdinando
err分享
err收藏
GLIAL-SPECIFIC TRANSCRIPTOMIC CHANGES IN HD
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2022-09-12
err0
PREAI
errBostrand, Sunniva M. K.; Seeker, Luise A.; Kazakou, Nina-Lydia; Bestard-Cuche, Nadine; Jaekel, Sarah; Henderson, Neil C.; van Roon-Mom, Willeke; Priller, Josef; Williams, Anna
err分享
err收藏
Delivery of oligonucleotide-based therapeutics: challenges and opportunities
errEMBO MOLECULAR MEDICINE
IF8.3
err2021-04-06
err212
errOAAI
errHammond, Suzan M.; Aartsma-Rus, Annemieke; Alves, Sandra; Borgos, Sven E.; Buijsen, Ronald A. M.; Collin, Rob W. J.; Covello, Giuseppina; Denti, Michela A.; Desviat, Lourdes R.; Echevarria, Lucia; Foged, Camilla; Gaina, Gisela; Garanto, Alejandro; Goyenvalle, Aurelie T.; Guzowska, Magdalena; Holodnuka, Irina; Jones, David R.; Krause, Sabine; Lehto, Taavi; Montolio, Marisol; Van Roon-Mom, Willeke; Arechavala-Gomeza, Virginia
err分享
err收藏
QRX-704, A NOVEL ANTISENSE OLIGONUCLEOTIDE THERAPY, DESIGNED TO PREVENT HD PATHOLOGY WHILE MAINTAINING HTT FUNCTION
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2018-09-01
err0
PREAI
errKlein, Pontus; Kameva, Zhana; Toonen, Lodewijk; Kim, Hyeongju; Caron, Nicholas; van der Graaf, Linda; Buil, Levi; van der Horst, Geert; Anthonijsz, Herma; van der Ham, Frits; Beumer, Wouter; Hayden, Michael; Song, Ji-Joon; van Roon-Mom, Willeke; Platenburg, Gerard
err分享
err收藏
A COMPARATIVE STUDY ON BLOOD AND BRAIN HD SIGNATURES: COMPARING MOUSE AND HUMAN HD GENE EXPRESSION DATA
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2018-09-01
err0
PREAI
errMina, Eleni; Toonen, Lodewijk; Kuijper, Elsa; Evers, Melvin; Roos, Marco; van Roon-Mom, Willeke
err分享
err收藏
COMMON DISEASE SIGNATURES FROM GENE EXPRESSION ANALYSIS IN HUNTINGTON'S DISEASE HUMAN BLOOD AND BRAIN
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2016-09-13
err0
PREAI
errMina, Eleni; van Roon-Mom, Willeke; Hettne, Kristina; van Zwet, Erik W.; Goeman, Jelle J.; Neri, Christian; 't Hoen, Peter A. C.; Mons, Barend; Roos, Marco
err分享
err收藏
PREVENTING FORMATION OF TOXIC N-TERMINAL HUNTINGTIN FRAGMENTS THROUGH ANTISENSE OLIGONUCLEOTIDE-MEDIATED PROTEIN MODIFICATION
errJOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
IF7.5
err2014-09-17
err0
PREAI
errEvers, M.; Casaca-Carreira, J.; Toonen, L.; Jahanshahi, A.; Temel, Y.; van Roon-Mom, W.
err分享
err收藏

研究方向

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合作学者
合作期刊
M
Michael R. Hayden
H 指数: 146 · 论文数: 1.2K
B
Britta Engelhardt
H 指数: 101 · 论文数: 390
A
Arthur Μ. Krieg
H 指数: 93 · 论文数: 403
J
Josef Priller
H 指数: 89 · 论文数: 579
H
Helga E. de Vries
H 指数: 86 · 论文数: 335
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