Urs A. Ochsner - Publications, H-index & Citations

Urs A. Ochsner

crestone

52H指数

97论文数

1.3W被引数

收录论文 36

发表时间

Safety and efficacy of CRS3123 in adults with a primary episode or first recurrence of Clostridioides difficile infection: a phase 2, randomised, double-blind, multicentre, vancomycin-controlled study CRS3123在艰难梭菌感染初次发作或首次复发成人中的安全性和有效性: 一项2期、随机、双盲、多中心、万古霉素对照研究

The Lancet Infectious Diseases

IF31

2026-01-22

OAAI

Thomas Louie; Wendy Ribble; Louis Boccumini; Katherine Johnson; Mary A De Groote; Joshua Day; Clifford Mason; Xicheng Sun; Jane Freeman; Kenan Gu; Glenn Tillotson; Mark H Wilcox; Nebojsa Janjic; Thale C Jarvis; Seema U Nayak; Urs A Ochsner; Jon B Bruss

Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated Listeria monocytogenes intracellular hollow-fibre model

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2022-08-05

OAAI

Patel, Swati; Chapagain, Moti; Mason, Clifford; Gingrich, Matthew; Athale, Shruti; Ribble, Wendy; Hoang, Teresa; Day, Joshua; Sun, Xicheng; Jarvis, Thale; Ochsner, Urs A.; Howe, David; Gumbo, Tawanda

IL-10 induces IgG4 production in NOD-scid Il2rγnull mice humanized by engraftment of peripheral blood mononuclear cells

ALLERGY

IF12

2021-08-07

OAAI

Cevhertas, Lacin; Ma, Siyuan; Stanic, Barbara; Ochsner, Urs; Jansen, Kirstin; Ferstl, Ruth; Frei, Remo; Chijoke, Obinna; Munz, Christian; Zhang, Luo; O'Mahony, Liam; Akdis, Mubeccel; van de Veen, Willem

A novel proangiogenic B cell subset is increased in cancer and chronic inflammation

SCIENCE ADVANCES

IF12.5

2020-05-15

OAAI

van de Veen, Willem; Globinska, Anna; Jansen, Kirstin; Straumann, Alex; Kubo, Terufumi; Verschoor, Danielle; Wirz, Oliver F.; Castro-Giner, Francesc; Tan, Ge; Ruckert, Beate; Ochsner, Urs; Herrmann, Marietta; Stanic, Barbara; van Splunter, Marloes; Huntjens, Daan; Wallimann, Alexandra; Guevara, Rodney J. Fonseca; Spits, Hergen; Ignatova, Desislava; Chang, Yun-Tsan; Fassnacht, Christina; Guenova, Emmanuella; Flatz, Lukas; Akdis, Cezmi A.; Akdis, Mubeccel

Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-12-20

OAAI

Lomeli, Barbara K.; Galbraith, Hal; Schettler, Jared; Saviolakis, George A.; El-Amin, Wael; Osborn, Blaire; Ravel, Jacques; Hazleton, Keith; Lozupone, Catherine A.; Evans, Ronald J.; Bell, Stacie J.; Ochsner, Urs A.; Jarvis, Thale C.; Baqar, Shahida; Janjic, Nebojsa

Comparison of regulatory B cells in asthma and allergic rhinitis

ALLERGY

IF12

2018-12-17

OAAI

Wirz, Oliver F.; Globinska, Anna; Ochsner, Urs; de Veen, Willem van; Eller, Esben; Christiansen, Elisabeth S.; Halken, Susanne; Nielsen, Christian; Bindslev-Jensen, Carsten; Anto, Josep M.; Bousquet, Jean; Akdis, Cezmi A.; Akdis, Mubeccel

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

FRONTIERS IN MICROBIOLOGY

IF4.5

2018-09-20

OAAI

De Groote, Mary A.; Jackson, Mary; Gonzalez-Juarrero, Mercedes; Li, Wei; Young, Casey L.; Wong, Christina; Graham, James; Day, Joshua; Hoang, Teresa; Jarvis, Thale C.; Ribble, Wendy; Sun, Xicheng; Ochsner, Urs A.

Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis

JOURNAL OF CLINICAL MICROBIOLOGY

IF5.4

2017-10-01

OAAI

De Groote, Mary A.; Sterling, David G.; Hraha, Thomas; Russell, Theresa M.; Green, Louis S.; Wall, Kirsten; Kraemer, Stephan; Ostroff, Rachel; Janjic, Nebojsa; Ochsner, Urs A.

Safety, Tolerability, Systemic Exposure, and Metabolism of CRS3123, a MethionyltRNA Synthetase Inhibitor Developed for Treatment of Clostridium difficile, in a Phase 1 Study

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-08-01

OAAI

Nayak, Seema U.; Griffiss, J. McLeod; Blumer, Jeffrey; O'Riordan, Mary Ann; Gray, Wesley; McKenzie, Robin; Jurao, Robert A.; An, Amanda T.; Le, Melissa; Bell, Stacie J.; Ochsner, Urs A.; Jarvis, Thale C.; Janjic, Nebojsa; Zenilman, Jonathan M.

Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection (vol 55, pg 391, 2017)

JOURNAL OF CLINICAL MICROBIOLOGY

IF5.4

2017-05-01

OAAI

De Groote, Mary Ann; Higgins, Michael; Hraha, Thomas; Wall, Kirsten; Wilson, Michael L.; Sterling, David G.; Janjic, Nebojsa; Reves, Randall; Ochsner, Urs A.; Belknap, Robert

Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection

JOURNAL OF CLINICAL MICROBIOLOGY

IF5.4

2017-02-01

OAAI

De Groote, Mary Ann; Higgins, Michael; Hraha, Thomas; Wall, Kirsten; Wilson, Michael L.; Sterling, David G.; Janjic, Nebojsa; Reves, Randall; Ochsner, Urs A.; Belknap, Robert

A novel, dual cytokine-secretion assay for the purification of human Th22 cells that do not co-produce IL-17A

ALLERGY

IF12

2015-11-04

PREAI

Wawrzyniak, M.; Ochsner, U.; Wirz, O.; Wawrzyniak, P.; van de Veen, W.; Akdis, C. A.; Akdis, M.

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2014-01-01

430

OAAI

Rohloff, John C.; Gelinas, Amy D.; Jarvis, Thale C.; Ochsner, Urs A.; Schneider, Daniel J.; Gold, Larry; Janjic, Nebojsa

Association of Toxin-Producing Clostridium botulinum with the Macroalga Cladophora in the Great Lakes

ENVIRONMENTAL SCIENCE & TECHNOLOGY

IF11.3

2013-03-04

PREAI

Chun, Chan Lan; Ochsner, Urs; Byappanahalli, Muruleedhara N.; Whitman, Richard L.; Tepp, William H.; Lin, Guangyun; Johnson, Eric A.; Peller, Julie; Sadowsky, Michael J.

Discovery and Analysis of 4H-Pyridopyrimidines, a Class of Selective Bacterial Protein Synthesis Inhibitors

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2010-11-01

OAAI

Ribble, Wendy; Hill, Walter E.; Ochsner, Urs A.; Jarvis, Thale C.; Guiles, Joseph W.; Janjic, Nebojsa; Bullard, James M.

Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2009-03-05

PREAI

Critchley, Ian A.; Green, Louis S.; Young, Casey L.; Bullard, James M.; Evans, Ron J.; Price, Melissa; Jarvis, Thale C.; Guiles, Joseph W.; Janjic, Nebojsa; Ochsner, Urs A.

Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2009-03-05

OAAI

Ochsner, Urs A.; Bell, Stacie J.; O'Leary, Ann L.; Hoang, Teresa; Stone, Kimberley Clawson; Young, Casey L.; Critchley, Ian A.; Janjic, Nebojsa

Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2009-01-01

OAAI

Green, Louis S.; Bullard, James M.; Ribble, Wendy; Dean, Frank; Ayers, David F.; Ochsner, Urs A.; Janjic, Nebojsa; Jarvis, Thale C.