David M. Shlaes - Publications, H-index & Citations

David M. Shlaes

AstraZeneca

51H指数

167论文数

1.0W被引数

收录论文 37

发表时间

Innovation, Nontraditional Antibacterial Drugs, and Clinical Utility

ACS INFECTIOUS DISEASES

IF3.8

2021-05-12

PREAI

Shlaes, David M.

Antibacterial Drugs: The Last Frontier

ACS INFECTIOUS DISEASES

IF3.8

2020-06-12

OAAI

Shlaes, David M.

Personal View of the Antibiotic Value Proposition

ACS INFECTIOUS DISEASES

IF3.8

2020-06-12

PREAI

Shlaes, David M.

Can Europe Pull It Together?

CLINICAL INFECTIOUS DISEASES

IF7.3

2020-02-15

PREAI

Shlaes, David M.

The Economic Conundrum for Antibacterial Drugs

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2019-12-20

OAAI

Shlaes, David M.

Research and Development of Antibiotics: The Next Battleground

ACS INFECTIOUS DISEASES

IF3.8

2015-05-05

PREAI

Shlaes, David M.

Simple Solutions Reflect Misunderstanding of Animal Antibiotic Use

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2015-01-01

OAAI

Metz, Matthew; Shlaes, David M.

Prioritized Current Unmet Needs for Antibacterial Therapies

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2014-08-01

OAAI

Spellberg, B.; Shlaes, D.

Eight More Ways To Deal with Antibiotic Resistance

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-08-01

OAAI

Metz, Matthew; Shlaes, David M.

Activities of Ceftazidime and Avibactam against β-Lactamase-Producing Enterobacteriaceae in a Hollow-Fiber Pharmacodynamic Model

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-06-01

OAAI

Coleman, Ken; Levasseur, Premavathy; Girard, Anne-Marie; Borgonovi, Monica; Miossec, Christine; Merdjan, Henri; Drusano, George; Shlaes, David; Nichols, Wright W.

In Memoriam: John P. Quinn, MD

CLINICAL INFECTIOUS DISEASES

IF7.3

2013-12-12

OAAI

Perez, Federico; Arias, Cesar A.; Bush, Karen; Drusano, George L.; Lolans, Karen; Munoz-Price, L. Silvia; Nicolau, David P.; Queenan, Anne Marie; Rice, Louis B.; Segreti, John; Shlaes, David M.; Weinstein, Robert A.; Bonomo, Robert A.

The FDA Reboot of Antibiotic Development

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2013-10-01

130

OAAI

Shlaes, David M.; Sahm, Dan; Opiela, Carol; Spellbergc, Brad

New β-lactam-β-lactamase inhibitor combinations in clinical development 临床开发中的新型 β-内酰胺-β-内酰胺酶抑制剂组合

ANTIMICROBIAL THERAPEUTICS REVIEWS: THE BACTERIAL CELL WALL AS AN ANTIMICROBIAL TARGET

IF0

2013-01-24

123

PREAI

Shlaes, David M.

Overcoming the challenges to developing new antibiotics

CURRENT OPINION IN PHARMACOLOGY

IF4.2

2012-10-01

PREAI

Shlaes, David M.; Spellberg, Brad

Fix the antibiotics pipeline

NATURE

IF48.5

2011-04-06

448

OAAI

Cooper, Matthew A.; Shlaes, David

Telithromycin and the FDA: implications for the future

LANCET INFECTIOUS DISEASES

IF31

2008-02-01

PREAI

Shlaes, David M.; Moellering, Robert C.

Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum β-lactamase inhibitors:: Evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-07-01

PREAI

Venkatesan, Aranapakam M.; Agarwal, Atul; Abe, Takao; Ushirogochi, Hideki; Yamamura, Itsuka; Ado, Mihira; Tsuyoshi, Takasaki; Dos Santos, Osvaldo; Gu, Yansong; Sum, Fuk-Wah; Li, Zhong; Francisco, Gerry; Lin, Yang-I; Petersen, Peter J.; Yang, Youjun; Kumagai, Toshio; Weiss, William J.; Shlaes, David M.; Knox, James R.; Mansour, Tarek S.

3,5-dioxopyrazolidines, novel inhibitors of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2006-02-01

OAAI

Yang, YJ; Severin, A; Chopra, R; Krishnamurthy, G; Singh, G; Hu, W; Keeney, D; Svenson, K; Petersen, PJ; Labthavikul, P; Shlaes, DM; Rasmussen, BA; Failli, AA; Shumsky, JS; Kutterer, KMK; Gilbert, A; Mansour, TS

Novel imidazole substituted 6-methylidene-penems as broad-spectrum β-lactamase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2004-11-01

PREAI

Venkatesan, AM; Agarwal, A; Abe, T; Ushirogochi, H; Yamamura, I; Kumagai, T; Petersen, PJ; Weiss, WJ; Lenoy, E; Yang, YJ; Shlaes, DM; Ryan, JL; Mansour, TS

Hydrophobic acetal and ketal derivatives of mannopeptimycin-α and desmethylhexahydromannopeptimycin-α:: Semisynthetic glycopeptides with potent activity against gram-positive bacteria

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-06-05

PREAI

Dushin, RG; Wang, TZ; Sum, PE; He, HY; Sutherland, AG; Ashcroft, JS; Graziani, EI; Koehn, FE; Bradford, PA; Petersen, PJ; Wheless, KL; How, D; Torres, N; Lenoy, EB; Weiss, WJ; Lang, SA; Projan, SJ; Shlaes, DM; Mansour, TS

研究方向