Pradeep K. Singh - Publications, H-index & Citations

Pradeep K. Singh

university of washington

48H指数

102论文数

1.6W被引数

收录论文 55

发表时间

Within-patient gene transfer between transiently and chronically infecting bacteria causes extreme antibiotic resistance during lung infections 在肺感染中，患者体内暂时感染和慢性感染的细菌之间的基因转移导致极端抗生素耐药性

Nature Microbiology

IF19.4

2026-07-23

OAAI

Sardar Karash; Hannah L. Betts; Matthew C. Radey; Samuel Lee; Sarah J. Morgan; Barbara J. Waddell; Sara Klee; Beth A. Traxler; Michael D. Parkins; Rafael E. Hernandez; Alison F. Feder; Colin Manoil; Pradeep K. Singh

Culture and Adaptation of Pseudomonas aeruginosa During Early Infection in Children With Cystic Fibrosis 铜绿假单胞菌(Pseudomonas aeruginosa)在囊性纤维化患儿早期感染过程中的培养与适应

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-10-01

PREAI

Mitra, Sumitra D.; Soneji, Maulin; Axline, Christopher M. R.; Hayden, Hillary S.; Radey, Matthew C.; Forsberg, Cara M.; Ozer, Egon A.; Wolter, Daniel J.; Pope, Christopher E.; Burns, Jane; Hoffman, Lucas R.; Mayer-Hamblett, Nicole; Singh, Pradeep; Hauser, Alan R.

Short tandem gene duplications as potential agents of genetic memory 短串联基因复制作为遗传记忆的潜在机制

MBIO

IF4.7

2025-10-01

PREAI

Lee, Samuel; Radey, Matthew; Singh, Pradeep; Manoil, Colin

Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation CFTR调节剂治疗后持续存在的铜绿假单胞菌感染遍布整个肺部，并驱动肺部炎症。

Cell Host & Microbe

IF18.7

2025-08-05

OAAI

Samantha L. Durfey; Siddhartha G. Kapnadak; Tahuanty Pena; Matthew M. Willmering; J. David Godwin; Mary E. Teresi; Sonya L. Heltshe; Anh T. Vo; Raul A. Villacreses; Ieva Aliukonyte; Linda Boyken; Mal R. Stroik; Sarah J. Morgan; Grace M. Wang; Hannah L. Betts; Shide Zhang; Christopher H. Goss; John P. Clancy; Moira L. Aitken; Chad Steele; Alison F. Feder; Charles R. Esther; Harm A.W.M. Tiddens; Jason C. Woods; David A. Stoltz; Pradeep K. Singh

Elexacaftor/Tezacaftor/Ivacaftor Markedly Reduces Aspergillus fumigatus in Cystic Fibrosis

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2024-11-01

PREAI

Morgan, Sarah J.; Nichols, David P.; Ni, Windy; Hong, Gina; Salipante, Stephen J.; Solomon, George M.; Rowe, Steven M.; Clancy, John P.; Cramer, Robert A.; Singh, Pradeep K.

Elexacaftor/tezacaftor/ivacaftor's effects on cystic fibrosis infections are maintained, but not increased, after 3.5 years of treatment

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-09-05

OAAI

Morgan, Sarah J.; Coulter, Ellis; Betts, Hannah L.; Solomon, George M.; Clancy, John P.; Rowe, Steven M.; Nichols, David P.; Singh, Pradeep K.

Cell-Free DNA Detects Pseudomonas aeruginosa Lung Infection in Modulator-treated People with Cystic Fibrosis

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2023-11-01

OAAI

Long, Dustin R.; Holmes, Elizabeth A.; Goss, Christopher H.; Singh, Pradeep K.; Waalkes, Adam; Salipante, Stephen J.

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist CFTR功能的药理学改善可迅速降低痰病原体密度，但肺部感染通常持续存在

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-05-15

OAAI

Nichols, David P.; Morgan, Sarah J.; Skalland, Michelle; Vo, Anh T.; Van Dalfsen, Jill M.; Singh, Sachinkumar B. P.; Ni, Wendy; Hoffman, Lucas R.; McGeer, Kailee; Heltshe, Sonya L.; Clancy, John P.; Rowe, Steven M.; Jorth, Peter; Singh, Pradeep K.

Acute Pulmonary Exacerbation Phenotypes in Patients with Cystic Fibrosis 囊性纤维化患者的急性肺加重表型

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2022-11-01

OAAI

Carter, Suzanne C.; Franciosi, Alessandro N.; O'Shea, Kate M.; O'Carroll, Orla M.; Sharma, Ashutosh; Bell, Aoife; Keogan, Brian; O'Reilly, Paul; Coughlan, Suzie; Law, Sheonagh M.; Gray, Robert D.; Hisert, Katherine B.; Singh, Pradeep K.; Cooke, Gordon; Grogan, Brenda; De Gascun, Cillian F.; Gallagher, Charles G.; Nicholson, Trevor T.; Quon, Bradley S.; McKone, Edward F.

Genome Capture Sequencing Selectively Enriches Bacterial DNA and Enables Genome-Wide Measurement of Intrastrain Genetic Diversity in Human Infections

MBIO

IF4.7

2022-10-26

OAAI

Hayden, Hillary S.; Joshi, Snehal; Radey, Mathew C.; Vo, Anh T.; Forsberg, Cara; Morgan, Sarah J.; Waalkes, Adam; Holmes, Elizabeth A.; Klee, Sara M.; Emond, Mary J.; Singh, Pradeep K.; Salipante, Stephen J.

A population-level strain genotyping method to study pathogen strain dynamics in human infections

JCI INSIGHT

IF6.1

2021-12-22

OAAI

Morgan, Sarah J.; Durfey, Samantha L.; Ravishankar, Sumedha; Jorth, Peter; Ni, Wendy; Skerrett, Duncan T.; Aitken, Moira L.; McKone, Edward F.; Salipante, Stephen J.; Radey, Matthew C.; Singh, Pradeep K.

Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections

MBIO

IF4.7

2021-12-21

OAAI

Durfey, Samantha L.; Pipavath, Sudhakar; Li, Anna; Vo, Anh T.; Ratjen, Anina; Carter, Suzanne; Morgan, Sarah J.; Radey, Matthew C.; Grogan, Brenda; Salipante, Stephen J.; Welsh, Michael J.; Stoltz, David A.; Goss, Christopher H.; McKone, Edward F.; Singh, Pradeep K.

Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial

THORAX

IF7.7

2021-10-27

OAAI

Nichols, David P.; Singh, Pradeep K.; Baines, Arthur; Caverly, Lindsay J.; Chmiel, James F.; GIbson, Ronald L.; Lascano, Jorge; Morgan, Sarah J.; Retsch-Bogart, George; Saiman, Lisa; Sadeghi, Hossein; Billings, Joanne L.; Heltshe, Sonya L.; Kirby, Shannon; Kong, Ada; Nick, Jerry A.; Mayer-Hamblett, Nicole

PROMISE: Working with the CF community to understand emerging clinical and research needs for those treated with highly effective CFTR modulator therapy 承诺: 与CF社区合作，了解使用高效CFTR调节剂治疗的患者的新兴临床和研究需求

JOURNAL OF CYSTIC FIBROSIS

IF6

2021-03-01

OAAI

Nichols, Dave P.; Donaldson, Scott H.; Frederick, Carla A.; Freedman, Steven D.; Gelfond, Daniel; Hoffman, Lucas R.; Kelly, Andrea; Narkewicz, Michael R.; Pittman, Jessica E.; Ratjen, Felix; Sagel, Scott D.; Rosenfeld, Margaret; Schwarzenberg, Sarah Jane; Singh, Pradeep K.; Solomon, George M.; Stalvey, Michael S.; Kirby, Shannon; VanDalfsen, Jill M.; Clancy, John P.; Rowe, Steven M.

Cystic Fibrosis Lung Function Decline after Within-Host Evolution Increases Virulence of Infecting Pseudomonas aeruginosa

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2021-03-01

OAAI

Jorth, Peter; Durfey, Samantha; Rezayat, Amir; Garudathri, Jayanthi; Ratjen, Anina; Staudinger, Benjamin J.; Radey, Matthew C.; Genatossio, Alan; McNamara, Sharon; Cook, David A.; Aitken, Moira L.; Gibson, Ronald L.; Yahr, Timothy L.; Singh, Pradeep K.

Pseudomonas aeruginosa Susceptibility Patterns and Associated Clinical Outcomes in People with Cystic Fibrosis following Approval of Aztreonam Lysine for Inhalation

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2021-02-17

OAAI

Keating, Claire L.; Zuckerman, Jonathan B.; Singh, Pradeep K.; McKevitt, Matthew; Gurtovaya, Oksana; Bresnik, Mark; Marshall, Bruce C.; Saiman, Lisa

Ivacaftor modifies cystic fibrosis neutrophil phenotype in subjects with R117H residual function CFTR mutations

EUROPEAN RESPIRATORY JOURNAL

IF21

2020-08-27

OAAI

Hardisty, Gareth R.; Law, Sheonagh M.; Carter, Suzanne; Grogan, Brenda; Singh, Pradeep K.; McKone, Edward F.; Gray, Robert D.

Correlation between Ivacaftor-induced CFTR Activation in Airway Epithelial Cells and Improved Lung Function: A Proof-of-Concept Study

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2020-08-01

OAAI

Debley, Jason S.; Barrow, Kaitlyn A.; Rich, Lucille M.; Singh, Pradeep; McKone, Edward F.; Nichols, David P.

Cell free DNA from respiratory pathogens is detectable in the blood plasma of Cystic Fibrosis patients

SCIENTIFIC REPORTS

IF3.9

2020-04-23

OAAI

Barrett, Sara L. Rassoulian; Holmes, Elizabeth A.; Long, Dustin R.; Shean, Ryan C.; Bautista, Gilbert E.; Ravishankar, Sumedha; Peddu, Vikas; Cookson, Brad T.; Singh, Pradeep K.; Greninger, Alexander L.; Salipante, Stephen J.

In Vivo Proteome of Pseudomonas aeruginosa in Airways of Cystic Fibrosis Patients 囊性纤维化患者气道中铜绿假单胞菌的体内蛋白质组

JOURNAL OF PROTEOME RESEARCH

IF3.6

2019-05-07

OAAI

Wu, Xia; Siehnel, Richard J.; Garudathri, Jayanthi; Staudinger, Benjamin J.; Hisert, Katherine B.; Ozer, Egon A.; Hauser, Alan R.; Eng, Jimmy K.; Manoil, Colin; Singh, Pradeep K.; Bruce, James E.

研究方向