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Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis Kamal, Mohamed A.; Kosloski, Matthew P.; Lai, Ching-Ha; Partridge, Michael A.; Rajadhyaksha, Manoj; Kanamaluru, Vanaja; Bansal, Ashish; Shabbir, Arsalan; Shumel, Brad; Ardeleanu, Marius; Richards, Susan M.; Yan, Hong; Xu, Christine R.; Rodriguez-Marco, Ainara; Xiao, Jing; Khokhar, Faisal A.; Gherardi, Guy; Babilonia, Elisa; Maloney, Jennifer; Mortensen, Eric; Akinlade, Bolanle; Braunstein, Ned; Stahl, Neil; Torri, Albert; Davis, John D.; Dicioccio, A. Thomas 分享 收藏
Discovery of first-in-class precision antibody drug conjugates with a potent SMARCA2/4 dual degrader payload that safely achieve maximal and tumor specific degradation and efficacy in mouse models Carter, J.; Agarwal, A.; Sivakumar, M.; Reichelderfer, A.; Park, J.; Osinubi, O.; Holmes, R.; Rager, J.; Stahl, N.; Cote, J.; Crossan, A.; Chen, C.; Pawley, S.; Wang, M.; Geeganage, S.; Lee, S.; Combs, A.; Scherle, P.; Buesking, A.; Ito, K. 分享 收藏
A therapeutic strategy to target distinct sources of IgE and durably reverse allergy Limnander, Andre; Kaur, Navneet; Asrat, Seblewongel; Tasker, Carley; Boyapati, Anita; Ben, Li-Hong; Janczy, John; Pedraza, Paulina; Abreu, Pablo; Chen, Wen-Chi; Godin, Stephen; Daniel, Benjamin J.; Chin, Harvey; Deveaux, Michelle; Lorenc, Karen Rodriguez; Sirulnik, Andres; Harari, Olivier; Stahl, Neil; Sleeman, Matthew A.; Murphy, Andrew J.; Yancopoulos, George D.; Orengo, Jamie M. 分享 收藏
A preoperative window-of-opportunity (WOO) study of imlunestrant in ER+, HER2-early breast cancer (EBC): Final analysis from EMBER-2 Neven, P.; Stahl, N.; Losada, M. J. Vidal; Jimenez, M. Martin; Kaufman, P. A.; Harbeck, N.; Hunt, K.; Carter, S. A.; Bidard, F. C.; Fasching, P.; Aftimos, P. G.; Wheatley, D.; Hamilton, E. P.; Aft, R.; Kulkarni, S.; Ismail-Khan, R.; Karacsonyi, C.; Estrem, S. T.; Ozbek, U.; Ciruelos, E. M. 分享 收藏
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Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial Herman, Gary A.; O'Brien, Meagan P.; Forleo-Neto, Eduardo; Sarkar, Neena; Isa, Flonza; Hou, Peijie; Chan, Kuo-Chen; Bar, Katharine J.; Barnabas, Ruanne, V; Barouch, Dan H.; Cohen, Myron S.; Hurt, Christopher B.; Burwen, Dale R.; Marovich, Mary A.; Musser, Bret J.; Davis, John D.; Turner, Kenneth C.; Mahmood, Adnan; Hooper, Andrea T.; Hamilton, Jennifer D.; Parrino, Janie; Subramaniam, Danise; Baum, Alina; Kyratsous, Christos A.; DiCioccio, A. Thomas; Stahl, Neil; Braunstein, Ned; Yancopoulos, George D.; Weinreich, David M. 分享 收藏
Casirivimab and Imdevimab for the Treatment of Hospitalized Patients With COVID-19 Casirivimab和Imdevimab用于治疗住院新型冠状病毒肺炎患者 Somersan-Karakaya, Selin; Mylonakis, Eleftherios; Menon, Vidya P.; Wells, Jason C.; Ali, Shazia; Sivapalasingam, Sumathi; Sun, Yiping; Bhore, Rafia; Mei, Jingning; Miller, Jutta; Cupelli, Lisa; Forleo-Neto, Eduardo; Hooper, Andrea T.; Hamilton, Jennifer D.; Pan, Cynthia; Pham, Viet; Zhao, Yuming; Hosain, Romana; Mahmood, Adnan; Davis, John D.; Turner, Kenneth C.; Kim, Yunji; Cook, Amanda; Kowal, Bari; Soo, Yuhwen; DiCioccio, A. Thomas; Geba, Gregory P.; Stahl, Neil; Lipsich, Leah; Braunstein, Ned; Herman, Gary A.; Yancopoulos, George D.; Weinreich, David M. 分享 收藏
COVID-19 prevention with subcutaneous administration of the monoclonal antibodies casirivimab and imdevimab: Subgroup analysis in participants with cardiovascular disease and diabetes O'Brien, Meagan P.; Forleo-Neto, Eduardo; Musser, Bret J.; Isa, Flonza; Chan, Kuo-Chen; Sarkar, Neena; Bar, Katharine J.; Barnabas, Ruanne V.; Barouch, Dan H.; Cohen, Myron S.; Marovich, Mary A.; Hou, Peijie; Heirman, Ingeborg; Davis, John D.; Turner, Kenneth C.; Ramesh, Divya; Mahmood, Adnan; Purcell, Lisa; Hooper, Andrea T.; Hamilton, Jennifer D.; Kim, Yunji; Baum, Alina; Kyratsous, Christos A.; Krainson, James; Perez-Perez, Richard; Mohseni, Rizwana; Kowal, Bari; DiCioccio, A. Thomas; Stahl, Neil; Lipsich, Leah; Braunstein, Ned; Herman, Gary; Yancopoulos, George D.; Weinreich, David M. 分享 收藏
Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 O'Brien, M. P.; Forleo-Neto, E.; Musser, B. J.; Isa, F.; Chan, K-C; Sarkar, N.; Bar, K. J.; Barnabas, R., V; Barouch, D. H.; Cohen, M. S.; Hurt, C. B.; Burwen, D. R.; Marovich, M. A.; Hou, P.; Heirman, I; Davis, J. D.; Turner, K. C.; Ramesh, D.; Mahmood, A.; Hooper, A. T.; Hamilton, J. D.; Kim, Y.; Purcell, L. A.; Baum, A.; Kyratsous, C. A.; Krainson, J.; Perez-Perez, R.; Mohseni, R.; Kowal, B.; DiCioccio, A. T.; Stahl, N.; Lipsich, L.; Braunstein, N.; Herman, G.; Yancopoulos, G. D.; Weinreich, D. M. 分享 收藏
Passive Prophylactic Administration with a Single Dose of Anti-Fel d 1 Monoclonal Antibodies REGN1908-1909 in Cat Allergen-induced Allergic Rhinitis A Randomized, Double-Blind, Placebo-controlled Clinical Trial Shamji, Mohamed H.; Singh, Iesha; Layhadi, Janice A.; Ito, Constance; Karamani, Angeliki; Kouser, Lubna; Sharif, Hanisah; Tang, Jiaqian; Handijiev, Sava; Parkin, Rebecca, V; Durham, Stephen R.; Kostic, Ana; Orengo, Jamie M.; DeVeaux, Michelle; Kamal, Mohamed; Stahl, Neil; Yancopoulos, George D.; Wang, Claire Q.; Radin, Allen R. 分享 收藏
Human Monoclonal Antibody Cocktail for the Treatment or Prophylaxis of Middle East Respiratory Syndrome Coronavirus Sivapalasingam, Sumathi; Saviolakis, George A.; Kulcsar, Kirsten; Nakamura, Aya; Conrad, Thomas; Hassanein, Mohamed; Sumner, Giane; Elango, Chinnasamy; Kamal, Mohamed A.; Eng, Simon; Kyratsous, Christos A.; Musser, Bret J.; Frieman, Matthew; Kantrowitz, Joel; Weinreich, David M.; Yancopoulos, George; Stahl, Neil; Lipsich, Leah 分享 收藏
REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19 Weinreich, D. M.; Sivapalasingam, S.; Norton, T.; Ali, S.; Gao, H.; Bhore, R.; Musser, B. J.; Soo, Y.; Rofail, D.; Im, J.; Perry, C.; Pan, C.; Hosain, R.; Mahmood, A.; Davis, J. D.; Turner, K. C.; Hooper, A. T.; Hamilton, J. D.; Baum, A.; Kyratsous, C. A.; Kim, Y.; Cook, A.; Kampman, W.; Kohli, A.; Sachdeva, Y.; Graber, X.; Kowal, B.; DiCioccio, T.; Stahl, N.; Lipsich, L.; Braunstein, N.; Herman, G.; Yancopoulos, G. D. 分享 收藏
Suptavumab for the Prevention of Medically Attended Respiratory Syncytial Virus Infection in Preterm Infants Simoes, Eric A. F.; Forleo-Neto, Eduardo; Geba, Gregory P.; Kamal, Mohamed; Yang, Feng; Cicirello, Helen; Houghton, Matthew R.; Rideman, Ronald; Zhao, Qiong; Benvin, Sarah L.; Hawes, Alicia; Fuller, Erin D.; Wloga, Elzbieta; Pizarro, Jose M. Novoa; Munoz, Flor M.; Rush, Scott A.; McLellan, Jason S.; Lipsich, Leah; Stahl, Neil; Yancopoulos, George D.; Weinreich, David M.; Kyratsous, Christos A.; Sivapalasingam, Sumathi 分享 收藏
Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis A Randomized Clinical Trial Worm, Margitta; Simpson, Eric L.; Thaci, Diamant; Bissonnette, Robert; Lacour, Jean-Philippe; Beissert, Stefan; Kawashima, Makoto; Ferrandiz, Carlos; Smith, Catherine H.; Beck, Lisa A.; Chan, Kuo-Chen; Chen, Zhen; Akinlade, Bolanle; Hultsch, Thomas; Staudinger, Heribert; Gadkari, Abhijit; Eckert, Laurent; Davis, John D.; Rajadhyaksha, Manoj; Graham, Neil M. H.; Pirozzi, Gianluca; Stahl, Neil; Yancopoulos, George D.; Ardeleanu, Marius 分享 收藏
Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation 需要用IL-4Rα 抗体dupilumab双重阻断IL-4和IL-13，以广泛抑制2型炎症 Le Floc'h, Audrey; Allinne, Jeanne; Nagashima, Kirsten; Scott, George; Birchard, Dylan; Asrat, Seblewongel; Bai, Yu; Lim, Wei Keat; Martin, Joel; Huang, Tammy; Potocky, Terra B.; Kim, Jee H.; Rafique, Ashique; Papadopoulos, Nicholas J.; Stahl, Neil; Yancopoulos, George D.; Murphy, Andrew J.; Sleeman, Matthew A.; Orengo, Jamie M. 分享 收藏
A study of dupilumab in the treatment of adolescents with eczema Cork, M. J.; Thaci, D.; Eichenfield, L. F.; Arkwright, P. D.; Hultsch, T.; Davis, J. D.; Zhang, Y.; Zhu, X.; Chen, Z.; Li, M.; Ardeleanu, M.; Teper, A.; Akinlade, B.; Gadkari, A.; Eckert, L.; Kamal, M. A.; Ruddy, M.; Graham, N. M. H.; Pirozzi, G.; Stahl, N.; DiCioccio, A. T.; Bansal, A. 分享 收藏
Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis Hirano, Ikuo; Dellon, Evan S.; Hamilton, Jennifer D.; Collins, Margaret H.; Peterson, Kathryn; Chehade, Mirna; Schoepfer, Alain M.; Safroneeva, Ekaterina; Rothenberg, Marc E.; Falk, Gary W.; Assouline-Dayan, Yehudith; Zhao, Qiong; Chen, Zhen; Swanson, Brian N.; Pirozzi, Gianluca; Mannent, Leda; Graham, Neil M. H.; Akinlade, Bolanle; Stahl, Neil; Yancopoulos, George D.; Radin, Allen 分享 收藏
Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis A Phase 3 Randomized Clinical Trial Simpson, Eric L.; Paller, Amy S.; Siegfried, Elaine C.; Boguniewicz, Mark; Sher, Lawrence; Gooderham, Melinda J.; Beck, Lisa A.; Guttman-Yassky, Emma; Pariser, David; Blauvelt, Andrew; Weisman, Jamie; Lockshin, Benjamin; Hultsch, Thomas; Zhang, Qin; Kamal, Mohamed A.; Davis, John D.; Akinlade, Bolanle; Staudinger, Heribert; Hamilton, Jennifer D.; Graham, Neil M. H.; Pirozzi, Gianluca; Gadkari, Abhijit; Eckert, Laurent; Stahl, Neil; Yancopoulos, George D.; Ruddy, Marcella; Bansal, Ashish 分享 收藏
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation Allinne, Jeanne; Scott, George; Lim, Wei Keat; Birchard, Dylan; Erjefalt, Jonas S.; Sanden, Caroline; Ben, Li-Hong; Agrawal, Amit; Kaur, Navneet; Kim, Jee Hae; Kamat, Vishal; Fury, Wen; Huang, Tammy; Stahl, Neil; Yancopoulos, George D.; Murphy, Andrew J.; Sleeman, Matthew A.; Orengo, Jamie M. 分享 收藏
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