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Nanoparticle encapsulation enables systemic IGF-Trap delivery to inhibit intracerebral glioma growth 纳米颗粒包封实现了系统性IGF-Trap递送以抑制颅内胶质瘤生长 Chen, Yinhsuan Michely; Chambon, Julien; Moquin, Alexandre; Hashimoto, Masakazu; Perrino, Stephanie; Leibovitch, Matthew; Benslimane, Yasmine; Hacariz, Orcun; Yang, Qin; Nakano, Ichiro; Meehan, Brian; Rak, Janusz; Gagne, Stephane 分享 收藏
GLIOMA STEM CELLS INDUCE VASECTASIA - A NON-ANGIOGENIC BRAIN TUMOUR NEOVASCULARIZATION PROCESS DRIVEN BY INTERCELLULAR EGFR TRANSFER THROUGH EXTRACELLULAR VESICLES Rak, Janusz; Spinelli, Cristiana; Adnani, Lata; Wong, Fang Cheng; Meehan, Brian; Montermini, Laura; Huang, Sidong; Kim, Minjun; Nishimura, Tamiko; Croul, Sidney; Nakano, Ichiro; Riazalhosseini, Yasser 分享 收藏
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Mesenchymal glioma stem cells trigger vasectasia-distinct neovascularization process stimulated by extracellular vesicles carrying EGFR Spinelli, Cristiana; Adnani, Lata; Meehan, Brian; Montermini, Laura; Huang, Sidong; Kim, Minjun; Nishimura, Tamiko; Croul, Sidney E.; Nakano, Ichiro; Riazalhosseini, Yasser; Rak, Janusz 分享 收藏
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SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria (vol 12, 5404, 2021) Xue, Yibo; Morris, Jordan L.; Yang, Kangning; Fu, Zheng; Zhu, Xianbing; Johnson, Fraser; Meehan, Brian; Witkowski, Leora; Yasmeen, Amber; Golenar, Tunde; Coatham, Mackenzie; Morin, Genevieve; Monast, Anie; Pilon, Virginie; Fiset, Pierre Olivier; Jung, Sungmi; Gonzalez, Anne V.; Camilleri-Broet, Sophie; Fu, Lili; Postovit, Lynne-Marie; Spicer, Jonathan; Gotlieb, Walter H.; Guiot, Marie-Christine; Rak, Janusz; Park, Morag; Lockwood, William; Foulkes, William D.; Prudent, Julien; Huang, Sidong 分享 收藏
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Detection of temozolomide-induced hypermutation and response to PD-1 checkpoint inhibitor in recurrent glioblastoma 复发性胶质母细胞瘤中替莫唑胺诱导的超突变和对PD-1检查点抑制剂的反应的检测 Daniel, Paul; Meehan, Brian; Sabri, Siham; Jamali, Fatemeh; Sarkaria, Jann N.; Choi, Dongsic; Garnier, Delphine; Kitange, Gaspar; Glennon, Kate, I; Paccard, Antoine; Karamchandani, Jason; Riazalhosseini, Yasser; Rak, Janusz; Abdulkarim, Bassam 分享 收藏
Synthetic glycans control gut microbiome structure and mitigate colitis in mice 合成聚糖控制肠道微生物组结构并减轻小鼠结肠炎 Tolonen, Andrew C.; Beauchemin, Nicholas; Bayne, Charlie; Li, Lingyao; Tan, Jie; Lee, Jackson; Meehan, Brian; Meisner, Jeffrey; Millet, Yves; LeBlanc, Gabrielle; Kottler, Robert; Rapp, Erdmann; Murphy, Chris; Turnbaugh, Peter J.; von Maltzahn, Geoffrey; Liu, Christopher M.; Vlieg, Johan E. T. van Hylckama 分享 收藏
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria Xue, Yibo; Morris, Jordan L.; Yang, Kangning; Fu, Zheng; Zhu, Xianbing; Johnson, Fraser; Meehan, Brian; Witkowski, Leora; Yasmeen, Amber; Golenar, Tunde; Coatham, Mackenzie; Morin, Genevieve; Monast, Anie; Pilon, Virginie; Fiset, Pierre Olivier; Jung, Sungmi; Gonzalez, Anne, V; Camilleri-Broet, Sophie; Fu, Lili; Postovit, Lynne-Marie; Spicer, Jonathan; Gotlieb, Walter H.; Guiot, Marie-Christine; Rak, Janusz; Park, Morag; Lockwood, William; Foulkes, William D.; Prudent, Julien; Huang, Sidong 分享 收藏
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Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles Tawil, Nadim; Bassawon, Rayhaan; Meehan, Brian; Nehme, Ali; Montermini, Laura; Gayden, Tenzin; De Jay, Nicolas; Spinelli, Cristiana; Chennakrishnaiah, Shilpa; Choi, Dongsic; Adnani, Lata; Zeinieh, Michele; Jabado, Nada; Kleinman, Claudia L.; Witcher, Michael; Riazalhosseini, Yasser; Key, Nigel S.; Schiff, David; Grover, Steven P.; Mackman, Nigel; Couturier, Charles P.; Petrecca, Kevin; Suva, Mario L.; Patel, Anoop; Tirosh, Itay; Najafabadi, Hamed; Rak, Janusz 分享 收藏
SMARCB1 loss induces druggable cyclinD1deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors Xue, Yibo; Zhu, Xianbing; Meehan, Brian; Venneti, Sriram; Martinez, Daniel; Morin, Genevieve; Maiga, Rayelle, I; Chen, Hongbo; Papadakis, Andreas, I; Johnson, Radia M.; O'Sullivan, Maureen J.; Erdreich-Epstein, Anat; Gotlieb, Walter H.; Park, Morag; Judkins, Alexander R.; Pelletier, Jerry; Foulkes, William D.; Rak, Janusz; Huang, Sidong 分享 收藏
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Identification of novel glycans that target gut microbiota-associated ammonia production Miller, Kelsey; Leff, Jonathan W.; Beauchemin, Nicholas; Liu, Christopher; Antalek, Mitchell; Belanger, David; Thieroff-Ekerdt, Ruth; Mahowald, Michael A.; Koziel, Margaret J.; Hartman, Madeline; Hecht, Maxwell; Murphy, Anastasia; Meehan, Brian 分享 收藏
SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer Xue, Yibo; Meehan, Brian; Fu, Zheng; Wang, Xue Qing D.; Fiset, Pierre Olivier; Rieker, Ralf; Levins, Cameron; Kong, Tim; Zhu, Xianbing; Morin, Genevieve; Skerritt, Lashanda; Herpel, Esther; Venneti, Sriram; Martinez, Daniel; Judkins, Alexander R.; Jung, Sungmi; Camilleri-Broet, Sophie; Gonzalez, Anne V.; Guiot, Marie-Christine; Lockwood, William W.; Spicer, Jonathan D.; Agaimy, Abbas; Pastor, William A.; Dostie, Josee; Rak, Janusz; Foulkes, William D.; Huang, Sidong 分享 收藏
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary CDK4/6抑制剂靶向SMARCA4-determined高钙血症性卵巢小细胞癌中的细胞周期蛋白D1缺陷 Xue, Yibo; Meehan, Brian; Macdonald, Elizabeth; Venneti, Sriram; Wang, Xue Qing D.; Witkowski, Leora; Jelinic, Petar; Kong, Tim; Martinez, Daniel; Morin, Genevieve; Firlit, Michelle; Abedini, Atefeh; Johnson, Radia M.; Cencic, Regina; Patibandla, Jay; Chen, Hongbo; Papadakis, Andreas I.; Auguste, Aurelie; de Rink, Iris; Kerkhoven, Ron M.; Bertos, Nicholas; Gotlieb, Walter H.; Clarke, Blaise A.; Leary, Alexandra; Witcher, Michael; Guiot, Marie-Christine; Pelletier, Jerry; Dostie, Josee; Park, Morag; Judkins, Alexander R.; Hass, Ralf; Levine, Douglas A.; Rak, Janusz; Vanderhyden, Barbara; Foulkes, William D.; Huang, Sidong 分享 收藏
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