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J

Jonathan C. Kagan

boston children's hospital and harvard medical school

64H指数
189论文数
2.2W被引数
收录论文 91
发表时间
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TRAM promotes Toll-like-receptor-free myddosome signal transductionTRAM促进无Toll样受体依赖的myddosome信号转导
errNature
IF48.5
err2026-09-23
err0
errOAAI
errDaniel Fisch; Vaani Ohri; Eleni Anastasakou; Lucia J. Wesemann; Joon H. Choi; Katherine E. Lindblad; Jonathan C. Kagan
err分享
err收藏
Functional chimeric mRNAs encode proteins in mammalian immunity功能性嵌合mRNAs编码哺乳动物免疫蛋白
errNature
IF48.5
err2026-09-02
err0
errOAAI
errOlivia Venezia; Harry Kane; Gang Du; Hannah D. Coughlan; Timothy M. Johanson; Hongshen Wang; Pathricia Tilstam; Samuel W. Kazer; Georgia Gunner; Daisy A. Hoagland; Megha G. Basavappa; Kanchana Ravichandran; Eren Ada; Ademi Zhakyp; Sandhya Kumar; Coco Duizer; Owen Searle; Chris Geo Provido; Leonel Joannas; Shilong Yang; Liam B. Healy; Qiankun Wang; Joia Capocchi; Bahawar Sharif Dhillon; Sarah Slavoff; Liang Shan; Jorge Henao-Mejia; Ruth A. Franklin; Isaac M. Chiu; Jose Ordovas-Montanes; Kate L. Jeffrey; Judy Lieberman; Rhys S. Allan; Jonathan C. Kagan; Hao Wu; Ruaidhrí Jackson
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Igniting antitumour immunity with cancer cell pyroptosis通过肿瘤细胞焦亡点燃抗肿瘤免疫
errNature Reviews Cancer
IF66.8
err2026-07-27
err0
PREAI
errXin Liu; Elena Goldberg; Jonathan C. Kagan; Hao Wu
err分享
err收藏
Purine and pyrimidine-based bacterial cyclic dinucleotides egress the phagosome and activate the innate immune sensor STING嘌呤和嘧啶基细菌环二核苷酸离开吞噬体并激活先天免疫传感器STING
errImmunity
IF26.3
err2026-07-17
err0
errOAAI
errStephanie A. Ragland; Katherine E. Lindblad; Yao Li; Joon H. Choi; Daniel Okin; Joshua Q. Mao; Desmond Richmond-Buccola; Daniela R. Coronado; Madison R. Brown; Scott B. Snapper; Philip J. Kranzusch; Jonathan C. Kagan
err分享
err收藏
Publisher Correction: Clinical development of cancer vaccines出版商更正: 癌症疫苗的临床开发
errNature Medicine
IF50
err2026-03-26
err0
PREAI
errJohn B. Haanen; Ton N. M. Schumacher; Jonathan C. Kagan; Edward F. Fritsch; Catherine J. Wu
err分享
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Clinical development of cancer vaccines癌症疫苗的临床开发
errNature Medicine
IF50
err2026-03-11
err0
PREAI
errJohn B. Haanen; Ton N. M. Schumacher; Jonathan C. Kagan; Edward F. Fritsch; Catherine J. Wu
err分享
err收藏
MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondriaMAVS寡聚化在过氧化物酶体中驱动更快速、更有效的抗病毒信号激活，相比线粒体。
errFEBS JOURNAL
IF4.2
err2025-12-01
err0
errOAAI
errRamos, Bruno; Sarabando, Jessica; Marques, Mariana; Kagan, Jonathan C.; Ribeiro, Daniela
err分享
err收藏
Discovery of functional chimeric mRNA encoded proteins in mammalian immunity
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errVenezia, Olivia; Kane, Harry; Wang, Hongshen; Tilstam, Pathricia; Ordovas-Montanes, Jose; Kagan, Jonathan C.; Jackson, Ruaidhri
err分享
err收藏
Towards a molecular and structural definition of cell death走向细胞死亡的分子与结构定义
errNature Structural & Molecular Biology
IF10.1
err2025-09-18
err0
PREAI
errEli Arama; Katia Cosentino; Peter E. Czabotar; Boyi Gan; Elizabeth Hartland; Xuejun Jiang; Jonathan C. Kagan; Shigekazu Nagata; Kate Schroder; Liming Sun; Daichao Xu; Junying Yuan
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An NLRP3-stimulatory adjuvant improves the immunogenicity of influenza virus vaccines in mice and non-human primates一种NLRP3刺激佐剂可增强小鼠和非人灵长类动物流感病毒疫苗的免疫原性
errMBIO
IF4.7
err2025-09-01
err0
errOAAI
errFinn, Kelsey; Chow, Jonathan; Zhivaki, Dania; Sengupta, Debrup; Concepcion, Holly; Komoroski, Veronica; MacFarlane, Carolyn; Coblentz, Philip D.; Chokshi, Milap; Matissek, Stephan; Gosselin, Emily; Alkekhia, Dahlia; Nikiforov, Anastasia; Lamberti, Nicolina; Iheanyichukwu, Victory; Kelly, Colin; Arinze, Chisom; Cornforth, Andrew; Elloul, Sivan; Kagan, Jonathan C.
err分享
err收藏
Regulation of inflammatory responses by pH-dependent transcriptional condensatespH依赖性转录凝聚体对炎症反应的调控
errCell
IF42.5
err2025-07-17
err0
errOAAI
errZhongyang Wu; Scott D. Pope; Nasiha S. Ahmed; Diana L. Leung; Yu Hong; Stephanie Hajjar; Cathleen Krabak; Zhe Zhong; Krishnan Raghunathan; Qiuyu Yue; Diya M. Anand; Elizabeth B. Kopp; Daniel Okin; Weiyi Ma; Ivan Zanoni; Jonathan C. Kagan; Jay R. Thiagarajah; Diana C. Hargreaves; Ruslan Medzhitov; Xu Zhou
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ARIES domains: functional signaling units of type I interferon responsesARIES结构域: I型干扰素反应的功能信号单位
errFEBS JOURNAL
IF4.2
err2025-02-18
err0
PREAI
errLandau, Lauren M.; Kagan, Jonathan C.
err分享
err收藏
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells
errNATURE IMMUNOLOGY
IF27.6
err2024-12-04
err0
errOAAI
errHolley, Caroline L.; Monteleone, Mercedes; Fisch, Daniel; Libert, Alexandre E. S.; Ju, Robert J.; Choi, Joon H.; Condon, Nicholas D.; Emming, Stefan; Crawford, Joanna; Lawrence, Grace M. E. P.; Coombs, Jared R.; Lefevre, James G.; Bajracharya, Rinie; Lahoud, Mireille H.; Yap, Alpha S.; Hamilton, Nicholas; Stehbens, Samantha J.; Kagan, Jonathan C.; Ariotti, Nicholas; Burgener, Sabrina S.; Schroder, Kate
err分享
err收藏
pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
errMOLECULAR CELL
IF16.6
err2024-07-01
err1
PREAI
errLandau, Lauren M.; Chaudhary, Neha; Tien, Yun Chen; Rogozinska, Magdalena; Joshi, Shakchhi; Yao, Conghui; Crowley, Joseph; Hullahalli, Karthik; Campbell, Ian W.; Waldor, Matthew K.; Haigis, Marcia; Kagan, Jonathan C.
err分享
err收藏
Structural transitions enable interleukin-18 maturation and signaling
errIMMUNITY
IF26.3
err2024-07-01
err4
PREAI
errDong, Ying; Bonin, Jeffrey P.; Devant, Pascal; Liang, Zhuoyi; Sever, Alexander I. M.; Mintseris, Julian; Aramini, James M.; Du, Gang; Gygi, Stephen P.; Kagan, Jonathan C.; Kay, Lewis E.; Wu, Hao
err分享
err收藏
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses
errSCIENCE IMMUNOLOGY
IF16.3
err2024-06-14
err0
PREAI
errRagland, Stephanie A.; Kagan, Jonathan C.
err分享
err收藏
Strategies of bacterial detection by inflammasomes炎症小体检测细菌的策略
errCELL CHEMICAL BIOLOGY
IF7.2
err2024-05-01
err1
PREAI
errJastrab, Jordan B.; Kagan, Jonathan C.
err分享
err收藏
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis
errSCIENCE IMMUNOLOGY
IF16.3
err2024-04-12
err26
PREAI
errBalasubramanian, Arumugam; Hsu, Alan Y.; Ghimire, Laxman; Tahir, Muhammad; Devant, Pascal; Fontana, Pietro; Du, Gang; Liu, Xing; Fabin, Dang; Kambara, Hiroto; Xie, Xuemei; Liu, Fei; Hasegawa, Tomoya; Xu, Rong; Yu, Hongbo; Chen, Mei; Kolakowski, Steven; Trauger, Sunia; Larsen, Martin Rossel; Wei, Wenyi; Wu, Hao; Kagan, Jonathan C.; Lieberman, Judy; Luo, Hongbo R.
err分享
err收藏
mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines
errMBIO
IF4.7
err2023-12-19
err9
errOAAI
errZhivaki, Dania; Gosselin, Emily A.; Sengupta, Debrup; Concepcion, Holly; Arinze, Chisom; Chow, Jonathan; Nikiforov, Anastasia; Komoroski, Veronica; Macfarlane, Carolyn; Sullivan, Caitlin; Kagan, Jonathan C.
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err收藏
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis线粒体内外膜的Gasdermin D透化作用加速并增强焦亡
errIMMUNITY
IF26.3
err2023-11-01
err97
errOAAI
errMiao, Rui; Jiang, Cong; Chang, Winston Y.; Zhang, Haiwei; An, Jinsu; Ho, Felicia; Chen, Pengcheng; Zhang, Han; Junqueira, Caroline; Amgalan, Dulguun; Liang, Felix G.; Zhang, Junbing; Evavold, Charles L.; Hafner-Bratkovic, Iva; Zhang, Zhibin; Fontana, Pietro; Xia, Shiyu; Waldeck-Weiermair, Markus; Pan, Youdong; Michel, Thomas; Bar-Peled, Liron; Wu, Hao; Kagan, Jonathan C.; Kitsis, Richard N.; Zhang, Peng; Liu, Xing; Lieberman, Judy
err分享
err收藏

研究方向

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合作学者
合作期刊
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Shizuo Akira
H 指数: 269 · 论文数: 1.5K
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Ramnik J. Xavier
H 指数: 186 · 论文数: 1.0K
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Katherine A. Fitzgerald
H 指数: 136 · 论文数: 609
Shigekazu Nagata 封面图
Shigekazu Nagata (Shigekazu Nagata)
H 指数: 133 · 论文数: 865
R
Ruslan Medzhitov
H 指数: 128 · 论文数: 347
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