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Shanisha Gordon-Mitchell

montefiore einstein comprehensive cancer centre
H指数:12
被引数:1,069

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A STAT3 degrader demonstrates efficacy in venetoclax resistant acute myeloid leukemia

STAT3降解剂在Venetoclax耐药急性髓系白血病中显示出疗效

Leukemia
IF13.4
2026-02-170
OAAI
Samarpana Chakraborty; Claudia Morganti; Kimberly Zaldana; Bianca Rivera Pena; Hui Zhang; Divij Verma; Nadege Gitego; Feiyang Ma; Srinivas Aluri; Kith Pradhan; Shanisha Gordon-Mitchell; Ioannis Mantzaris; Mendel Goldfinger; Eric Feldman; Kira Gritsman; Yang Shi; Stefan Hubner; Yi Hua Qiu; Brandon D. Brown; Abdullah Khasawneh; Anna Skwarska; Eduardo Sabino de Camargo Magalhães; Amit Verma; Marina Konopleva; Yoko Tabe; Evripidis Gavathiotis; Simona Colla; Jared Gollob; Joyoti Dey; Steven M. Kornblau; Sergei B. Koralov; Keisuke Ito; Aditi Shastri
Splicing regulatory dynamics for precision analysis and treatment of heterogeneous leukemias

异质性白血病精准分析与治疗的剪接调控动力学

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-05-070
PRE
Venkatasubramanian, Meenakshi; Schwartz, Leya; Ramachandra, Nandini; Bennett, Joshua; Subramanian, Krithika R.; Chen, Xiaoting; Gordon-Mitchell, Shanisha; Fromowitz, Ariel; Pradhan, Kith; Shechter, David; Sahu, Srabani; Heiser, Diane; Scherle, Peggy; Chetal, Kashish; Kulkarni, Aishwarya; Lee, Davy; Zhou, Jeff; Myers, Kasiani C.; Tseng, Elizabeth; Weirauch, Matthew T.; Grimes, H. Leighton; Starczynowski, Daniel T.; Verma, Amit; Salomonis, Nathan
Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: a phase 1b/2 clinical trial and correlative analyses

谷氨酰胺酶抑制联合氮杂胞苷治疗骨髓增生异常综合征: 1b/2期临床试验及相关分析

NATURE CANCER
IF28.5
2024-09-190
PRE
Dinardo, Courtney D.; Verma, Divij; Baran, Natalia; Bhagat, Tushar D.; Skwarska, Anna; Lodi, Alessia; Saxena, Kapil; Cai, Tianyu; Su, Xiaoping; Guerra, Veronica A.; Poigaialwar, Gowri; Kuruvilla, Vinitha M.; Konoplev, Sergej; Gordon-Mitchell, Shanisha; Pradhan, Kith; Aluri, Srinivas; Hackman, G. Lavender; Chaudhry, Sovira; Collins, Meghan; Sweeney, Shannon R.; Busquets, Jonathan; Rathore, Atul Singh; Deng, Qing; Green, Michael R.; Grant, Steven; Demo, Susan; Choudhary, Gaurav S.; Sahu, Srabani; Agarwal, Beamon; Spodek, Mason; Thiruthuvanathan, Victor; Will, Britta; Steidl, Ulrich; Tippett, George D.; Burger, Jan; Borthakur, Gautam; Jabbour, Elias; Pemmaraju, Naveen; Kadia, Tapan; Kornblau, Steven; Daver, Naval G.; Naqvi, Kiran; Short, Nicholas J.; Garcia-Manero, Guillermo; Tiziani, Stefano; Verma, Amit; Konopleva, Marina
Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-02-201
OAAI
Aminov, Sarah; Giricz, Orsi; Melnekoff, David T.; Sica, R. Alejandro; Polishchuk, Veronika; Papazoglu, Cristian; Yates, Bonnie; Wang, Hao-Wei; Sahu, Srabani; Wang, Yanhua; Gordon-Mitchell, Shanisha; Leshchenko, Violetta V.; Schinke, Carolina; Pradhan, Kith; Aluri, Srinivas; Sohn, Moah; Barta, Stefan K.; Agarwal, Beamon; Goldfinger, Mendel; Mantzaris, Ioannis; Shastri, Aditi; Matsui, William; Steidl, Ulrich; Brody, Joshua D.; Shah, Nirali N.; Parekh, Samir; Verma, Amit
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations
ELIFE
IF0
2022-08-3040
OA
Choudhary, Gaurav S.; Pellagatti, Andrea; Agianian, Bogos; Smith, Molly A.; Bhagat, Tushar D.; Gordon-Mitchell, Shanisha; Sahu, Srabani; Pandey, Sanjay; Shah, Nishi; Aluri, Srinivas; Aggarwal, Ritesh; Aminov, Sarah; Schwartz, Leya; Steeples, Violetta; Booher, Robert N.; Ramachandra, Murali; Samson, Maria; Carbajal, Milagros; Pradhan, Kith; Bowman, Teresa, V; Pillai, Manoj M.; Will, Britta; Wickrema, Amittha; Shastri, Aditi; Bradley, Robert K.; Martell, Robert E.; Steidl, Ulrich G.; Gavathiotis, Evripidis; Boultwood, Jacqueline; Starczynowski, Daniel T.; Verma, Amit
Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer (vol 15, 70, 2022)
JOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
2022-07-260
OAAI
Zhang, Yang; Chen, Xiaoyi; Wang, Huamin; Gordon-Mitchell, Shanisha; Sahu, Srabani; Bhagat, Tushar D.; Choudhary, Gaurav; Aluri, Srinivas; Pradhan, Kith; Sahu, Plabani; Carbajal, Milagros; Zhang, Hui; Agarwal, Beamon; Shastri, Aditi; Martell, Robert; Starczynowski, Daniel; Steidl, Ulrich; Maitra, Anirban; Verma, Amit
Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer
JOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
2022-05-2316
OAAI
Zhang, Yang; Chen, Xiaoyi; Wang, Huamin; Gordon-Mitchell, Shanisha; Sahu, Srabani; Bhagat, Tushar D.; Choudhary, Gaurav; Aluri, Srinivas; Pradhan, Kith; Sahu, Plabani; Carbajal, Milagros; Zhang, Hui; Agarwal, Beamon; Shastri, Aditi; Martell, Robert; Starczynowski, Daniel; Steidl, Ulrich; Maitra, Anirban; Verma, Amit
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster
NATURE MEDICINE
IF50
2022-03-0720
OA
Jasra, Sakshi; Giricz, Orsi; Zeig-Owens, Rachel; Pradhan, Kith; Goldfarb, David G.; Barreto-Galvez, Angelica; Silver, Alexander J.; Chen, Jiahao; Sahu, Srabani; Gordon-Mitchell, Shanisha; Choudhary, Gaurav S.; Aluri, Srinivas; Bhagat, Tushar D.; Shastri, Aditi; Bejan, Cosmin A.; Stockton, Shannon S.; Spaulding, Travis P.; Thiruthuvanathan, Victor; Goto, Hiroki; Gerhardt, Jeannine; Haider, Syed Hissam; Veerappan, Arul; Bartenstein, Matthias; Nwankwo, George; Landgren, Ola; Weiden, Michael D.; Lekostaj, Jacqueline; Bender, Ryan; Fletcher, Frederick; Greenberger, Lee; Ebert, Benjamin L.; Steidl, Ulrich; Will, Britta; Nolan, Anna; Madireddy, Advaitha; Savona, Michael R.; Prezant, David J.; Verma, Amit
ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine
BLOOD CANCER JOURNAL
IF11.6
2021-09-2139
OAAI
Rahmani, Nora E.; Ramachandra, Nandini; Sahu, Srabani; Gitego, Nadege; Lopez, Andrea; Pradhan, Kith; Bhagat, Tushar D.; Gordon-Mitchell, Shanisha; Pena, Bianca Rivera; Kazemi, Mohammad; Rao, Keshav; Giricz, Orsi; Maqbool, Shahina Bano; Olea, Raul; Zhao, Yongmei; Zhang, Jinghang; Dolatshad, Hamid; Tittrea, Vickram; Tatwavedi, Dharamveer; Singh, Shalini; Lee, Juseong; Sun, Tianyu; Steidl, Ulrich; Shastri, Aditi; Inoue, Daichi; Abdel-Wahab, Omar; Pellagatti, Andrea; Gavathiotis, Evripidis; Boultwood, Jacqueline; Verma, Amit
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts
ELIFE
IF0
2019-11-01126
OA
Bhagat, Tushar D.; Von Ahrens, Dagny; Dawlaty, Meelad; Zou, Yiyu; Baddour, Joelle; Achreja, Abhinav; Zhao, Hongyun; Yang, Lifeng; Patel, Brijesh; Kwak, Changsoo; Choudhary, Gaurav S.; Gordon-Mitchell, Shanisha; Aluri, Srinivas; Bhattacharyya, Sanchari; Sahu, Srabani; Bhagat, Prafulla; Yu, Yiting; Bartenstein, Matthias; Giricz, Orsi; Suzuki, Masako; Sohal, Davendra; Gupta, Sonal; Guerrero, Paola A.; Batra, Surinder; Goggins, Michael; Steidl, Ulrich; Greally, John; Agarwal, Beamon; Pradhan, Kith; Banerjee, Debabrata; Nagrath, Deepak; Maitra, Anirban; Verma, Amit
U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

U2AF1突变在髓系恶性肿瘤中诱导致癌IRAK4亚型并激活先天免疫途径

NATURE CELL BIOLOGY
IF19.1
2019-04-22170
OAAI
Smith, Molly A.; Choudhary, Gaurav S.; Pellagatti, Andrea; Choi, Kwangmin; Bolanos, Lyndsey C.; Bhagat, Tushar D.; Gordon-Mitchell, Shanisha; Von Ahrens, Dagny; Pradhan, Kith; Steeples, Violetta; Kim, Sanghyun; Steidl, Ulrich; Walter, Matthew; Fraser, Iain D. C.; Kulkarni, Aishwarya; Salomonis, Nathan; Komurov, Kakajan; Boultwood, Jacqueline; Verma, Amit; Starczynowski, Daniel T.
Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2019-03-0467
OA
Shenoy, Niraj; Bhagat, Tushar D.; Cheville, John; Lohse, Christine; Bhattacharyya, Sanchari; Tischer, Alexander; Machha, Venkata; Gordon-Mitchell, Shanisha; Choudhary, Gaurav; Wong, Li-Fan; Gross, LouAnn; Ressigue, Emily; Leibovich, Bradley; Boorjian, Stephen A.; Steidl, Ulrich; Wu, Xiaosheng; Pradhan, Kith; Gartrell, Benjamin; Agarwal, Beamon; Pagliaro, Lance; Suzuki, Masako; Greally, John M.; Rakheja, Dinesh; Thompson, R. Houston; Susztak, Katalin; Witzig, Thomas; Zou, Yiyu; Verma, Amit
Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2018-11-0569
OAAI
Shastri, Aditi; Choudhary, Gaurav; Teixeira, Margarida; Gordon-Mitchell, Shanisha; Ramachandra, Nandini; Bernard, Lumie; Bhattacharyya, Sanchari; Lopez, Robert; Pradhan, Kith; Giricz, Orsolya; Ravipati, Goutham; Wong, Li-Fan; Cole, Sally; Bhagat, Tushar D.; Feld, Jonathan; Dhar, Yosman; Bartenstein, Matthias; Thiruthuvanathan, Victor J.; Wickrema, Amittha; Ye, B. Hilda; Frank, David A.; Pellagatti, Andrea; Boultwood, Jacqueline; Zhou, Tianyuan; Kim, Youngsoo; MacLeod, Robert; Epling-Burnette, P. K.; Ye, Minwei; McCoon, Patricia; Woessner, Richard; Steidl, Ulrich; Will, Britta; Verma, Amit
Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia
CANCER RESEARCH
IF16.6
2016-08-1434
OAAI
Bachegowda, Lohith; Morrone, Kerry; Winski, Shannon L.; Mantzaris, Ioannis; Bartenstein, Matthias; Ramachandra, Nandini; Giricz, Orsi; Sukrithan, Vineeth; Nwankwo, George; Shahnaz, Samira; Bhagat, Tushar D.; Bhattacharyya, Sanchari; Assal, Amer; Shastri, Aditi; Gordon-Mitchell, Shanisha; Pellagatti, Andrea; Boultwood, Jacqueline; Schinke, Carolina; Yu, Yiting; Guha, Chandan; Rizzi, James; Garrus, Jennifer; Brown, Suzy; Wollenberg, Lance; Hogeland, Grant; Wright, Dale; Munson, Mark; Rodriguez, Mareli; Gross, Stefan; Chantry, David; Zou, Yiyu; Platanias, Leonidas C.; Burgess, Laurence E.; Pradhan, Kith; Steidl, Ulrich; Verma, Amit

研究方向

暂未获取到该数据
K
Kith Pradhan
H 指数:42论文数:321被引数:1.0万
U
Ulrich Steidl
H 指数:58论文数:454被引数:1.0万
S
Srabani Sahu
H 指数:17论文数:108被引数:1,961
T
Tushar D. Bhagat
H 指数:42论文数:194被引数:5,434
A
Aditi Shastri
H 指数:24论文数:307被引数:2,040
A
Amit Verma
H 指数:71论文数:708被引数:1.9万
S
Srinivas Aluri
H 指数:15论文数:115被引数:932
G
Gaurav S. Choudhary
H 指数:27论文数:144被引数:3,448
B
Beamon Agarwal
H 指数:25论文数:87被引数:4,275
D
Daniel T. Starczynowski
H 指数:41论文数:240被引数:1.1万