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A

A. Heine

Philipps University Marburg

47H指数
493论文数
7.4K被引数
收录论文 81
发表时间
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Pain Reduction in Patellofemoral Knee Patients During 3-Month Intervention with Biomechanical and Sensorimotor Foot Orthoses: A Randomized Controlled Clinical Study
errBIOMEDICINES
IF3.9
err2024-12-27
err0
errOAAI
errSimon, Steven; Heine, Andreas; Dully, Jonas; Dindorf, Carlo; Ludwig, Oliver; Froehlich, Michael; Becker, Stephan
err分享
err收藏
Potent anti-coronaviral activity of pateamines and new insights into their mode of action
errHELIYON
IF3.6
err2024-07-01
err1
errOAAI
errMagari, Francesca; Messner, Henri; Salisch, Florian; Schmelzle, Stella M.; van Zandbergen, Ger; Fuerstner, Alois; Ziebuhr, John; Heine, Andreas; Mueller-Ruttloff, Christin; Gruenweller, Arnold
err分享
err收藏
Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC
errACS OMEGA
IF4.3
err2023-11-20
err2
errOAAI
errGardonyi, Marina; Hasewinkel, Christian; Wallbaum, Johanna; Wollenhaupt, Jan; Weiss, Manfred S.; Klebe, Gerhard; Reuter, Klaus; Heine, Andreas
err分享
err收藏
Mutational Studies of Aldose Reductase to Trace a Transient Pocket Opening and to Explain Ligand Affinity Cliffs
errCHEMMEDCHEM
IF3.4
err2023-07-05
err0
errOAAI
errKlee, Lea-Sophie; Gardonyi, Marina; Huefner, Tobias; Heine, Andreas; Klebe, Gerhard
err分享
err收藏
Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-01-01
err5
PREAI
errHeyder, Lukas; Hochban, Phil M. M.; Taylor, Corey; Chevillard, Florent; Siefker, Christof; Iking, Christian; Borchardt, Hannes; Aigner, Achim; Klebe, Gerhard; Heine, Andreas; Kolb, Peter; Diederich, Wibke E.
err分享
err收藏
Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease
errCHEMMEDCHEM
IF3.4
err2022-11-21
err4
errOAAI
errBraun, Niklas J.; Huber, Simon; Schmacke, Luna C.; Heine, Andreas; Steinmetzer, Torsten
err分享
err收藏
Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-08-01
err10
PREAI
errPilgram, Oliver; Keils, Aline; Benary, Gerrit E.; Mueller, Janis; Merkl, Stefan; Ngaha, Sandrine; Huber, Simon; Chevillard, Florent; Harbig, Anne; Magdolen, Viktor; Heine, Andreas; Bottcher-Friebertshauser, Eva; Steinmetzer, Torsten
err分享
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Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase
errACS CHEMICAL BIOLOGY
IF3.8
err2022-07-11
err8
errOAAI
errSebastiani, Maurice; Behrens, Christina; Doerr, Stefanie; Gerber, Hans-Dieter; Benazza, Rania; Hernandez-Alba, Oscar; Cianferani, Sarah; Klebe, Gerhard; Heine, Andreas; Reuter, Klaus
err分享
err收藏
19F-NMR Unveils the Ligand-Induced Conformation of a Catalytically Inactive Twisted Homodimer of tRNA-Guanine Transglycosylase
errACS CHEMICAL BIOLOGY
IF3.8
err2022-06-28
err0
PREAI
errNguyen, Andreas; Gemmecker, Gerd; Softley, Charlotte A.; Movsisyan, Levon D.; Pfaffeneder, Toni; Heine, Andreas; Reuter, Klaus; Diederich, Francois; Sattler, Michael; Klebe, Gerhard
err分享
err收藏
Structure-Based Optimization and Characterization of MacrocyclicZika Virus NS2B-NS3 Protease Inhibitors br
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-04-27
err15
PREAI
errHuber, Simon; Braun, Niklas J.; Schmacke, Luna C.; Quek, Jun Ping; Murra, Robin; Bender, Daniela; Hildt, Eberhard; Luo, Dahai; Heine, Andreas; Steinmetzer, Torsten
err分享
err收藏
Unraveling a Ligand-Induced Twist of a Homodimeric Enzyme by Pulsed Electron-Electron Double Resonance
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2021-09-21
err8
errOAAI
errDzung Nguyen; Abdullin, Dinar; Heubach, Caspar A.; Pfaffeneder, Toni; Nguyen, Andreas; Heine, Andreas; Reuter, Klaus; Diederich, Francois; Schiemann, Olav; Klebe, Gerhard
err分享
err收藏
Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface
errACS CHEMICAL BIOLOGY
IF3.8
err2021-06-03
err2
PREAI
errDzung Nguyen; Xie, Xiulan; Jakobi, Stephan; Terwesten, Felix; Metz, Alexander; Nguyen, T. X. Phong; Palchykov, Vitalii A.; Heine, Andreas; Reuter, Klaus; Klebe, Gerhard
err分享
err收藏
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-01-20
err2
PREAI
errSandner, Anna; Ngo, Khang; Schiebel, Johannes; Pizarroso, Angela Ilse Marca; Schmidt, Linda; Wenzel, Benjamin; Steinmetzer, Torsten; Ostermann, Andreas; Heine, Andreas; Klebe, Gerhard
err分享
err收藏
The Importance of Charge in Perturbing the Aromatic Glue Stabilizing the Protein-Protein Interface of Homodimeric tRNA-Guanine Transglycosylase
errACS CHEMICAL BIOLOGY
IF3.8
err2020-11-09
err3
errOAAI
errNguyen, Andreas; Dzung Nguyen; Tran Xuan Phong Nguyen; Sebastiani, Maurice; Doerr, Stefanie; Hernandez-Alba, Oscar; Debaene, Francois; Cianferani, Sarah; Heine, Andreas; Klebe, Gerhard; Reuter, Klaus
err分享
err收藏
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding Poses
errCHEMMEDCHEM
IF3.4
err2020-10-30
err20
errOAAI
errWienen-Schmidt, Barbara; Oebbeke, Matthias; Ngo, Khang; Heine, Andreas; Klebe, Gerhard
err分享
err收藏
Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses
errCHEMMEDCHEM
IF3.4
err2020-06-30
err36
errOAAI
errBraun, Niklas J.; Quek, Jun P.; Huber, Simon; Kouretova, Jenny; Rogge, Dorothee; Lang-Henkel, Heike; Cheong, Ezekiel Z. K.; Chew, Bing L. A.; Heine, Andreas; Luo, Dahai; Steinmetzer, Torsten
err分享
err收藏
Structure-Based Design of FXIIIa-Blockers: Addressing a Transient Hydrophobic Pocket in the Active Site of FXIIIa
errCHEMMEDCHEM
IF3.4
err2020-04-07
err3
errOAAI
errStieler, Martin; Buechold, Christian; Schmitt, Marisa; Heine, Andreas; Hils, Martin; Pasternack, Ralf; Klebe, Gerhard
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err收藏
Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach
errCHEMMEDCHEM
IF3.4
err2020-03-18
err5
errOAAI
errKonstantinidou, Markella; Magari, Francesca; Sutanto, Fandi; Haupenthal, Joerg; Jumde, Varsha R.; Unver, M. Yagiz; Heine, Andreas; Camacho, Carlos Jamie; Hirsch, Anna K. H.; Klebe, Gerhard; Domling, Alexander
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Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors
errACS CHEMICAL BIOLOGY
IF3.8
err2020-02-06
err12
PREAI
errGloeckner, Steffen; Ngo, Khang; Sager, Christoph P.; Huefner-Wulsdorf, Tobias; Heine, Andreas; Klebe, Gerhard
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err收藏
Protein-Induced Change in Ligand Protonation during Trypsin and Thrombin Binding: Hint on Differences in Selectivity Determinants of Both Proteins?
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-02-03
err7
PREAI
errKhang Ngo; Collins-Kautz, Chelsey; Gerstenecker, Stefan; Wagner, Bjoern; Heine, Andreas; Klebe, Gerhard
err分享
err收藏

研究方向

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H 指数: 179 · 论文数: 1.7K
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R
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C
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