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Inhibition and transport mechanisms of the ABC transporter hMRP5 ABC转运蛋白hMRP5的抑制和转运机制 Huang, Ying; Xue, Chenyang; Bu, Ruiqian; Wu, Cang; Li, Jiachen; Zhang, Jinqiu; Chen, Jinyu; Shi, Zhaoying; Chen, Yonglong; Wang, Yong; Liu, Zhongmin 分享 收藏
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Conformational cycle of human polyamine transporter ATP13A2 Mu, Jianqiang; Xue, Chenyang; Fu, Lei; Yu, Zongjun; Nie, Minhan; Wu, Mengqi; Chen, Xinmeng; Liu, Kun; Bu, Ruiqian; Huang, Ying; Yang, Baisheng; Han, Jianming; Jiang, Qianru; Chan, Kevin C.; Zhou, Ruhong; Li, Huilin; Huang, Ancheng; Wang, Yong; Liu, Zhongmin 分享 收藏
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The pattern of apolipoprotein A-I lysine carbamylation reflects its lipidation state and the chemical environment within human atherosclerotic aorta Battle, Shawna; Gogonea, Valentin; Willard, Belinda; Wang, Zeneng; Fu, Xiaoming; Huang, Ying; Graham, Linda M.; Cameron, Scott J.; DiDonato, Joseph A.; Crabb, John W.; Hazen, Stanley L. 分享 收藏
Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies Huang, Ying; Sendzik, Martin; Zhang, Jeff; Gao, Zhenting; Sun, Yongfeng; Wang, Long; Gu, Justin; Zhao, Kehao; Yu, Zhengtian; Zhang, Lijun; Zhang, Qiong; Blanz, Joachim; Chen, Zijun; Dubost, Valerie; Fang, Douglas; Feng, Lijian; Fu, Xingnian; Kiffe, Michael; Li, Ling; Luo, Fangjun; Luo, Xiao; Mi, Yuan; Mistry, Prakash; Pearson, David; Piaia, Alessandro; Scheufler, Clemens; Terranova, Remi; Weiss, Andreas; Zeng, Jue; Zhang, Hailong; Zhang, Jiangwei; Zhao, Mengxi; Dillon, Michael P.; Jeay, Sebastien; Qi, Wei; Moggs, Jonathan; Pissot-Soldermann, Carole; Li, En; Atadja, Peter; Lingel, Andreas; Oyang, Counde 分享 收藏
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Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis Zamanian-Daryoush, Maryam; Gogonea, Valentin; DiDonato, Anthony J.; Buffa, Jennifer A.; Choucair, Ibrahim; Levison, Bruce S.; Hughes, Randall A.; Ellington, Andrew D.; Huang, Ying; Li, Xinmin S.; DiDonato, Joseph A.; Hazen, Stanley L. 分享 收藏
Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma Huang, Xianhai; Brubaker, Jason; Zhou, Wei; Biju, Purakkattle J.; Xiao, Li; Shao, Ning; Huang, Ying; Dong, Li; Liu, Zhidan; Bitar, Rema; Buevich, Alexei; Jung, Joon; Peterson, Scott L.; Butcher, John W.; Close, Joshua; Martinez, Michelle; MacCoss, Rachel N.; Zhang, Hongjun; Crawford, Scott; McCormick, Kevin D.; Aslanian, Robert; Nargund, Ravi; Correll, Craig; Gervais, Francois; Qiu, Hongchen; Yang, Xiaoxin; Garlisi, Charles; Rindgen, Diane; Maloney, Kevin M.; Siliphaivanh, Phieng; Palani, Anandan 分享 收藏
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An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED Qi, Wei; Zhao, Kehao; Gu, Justin; Huang, Ying; Wang, Youzhen; Zhang, Hailong; Zhang, Man; Zhang, Jeff; Yu, Zhengtian; Li, Ling; Teng, Lin; Chuai, Shannon; Zhang, Chao; Zhao, Mengxi; Chan, HoMan; Chen, Zijun; Fang, Douglas; Qi, Fei; Feng, Leying; Feng, Lijian; Gao, Yuan; Ge, Hui; Ge, Xinjian; Lingel, Andreas; Li, Guobin; Lin, Ying; Liu, Yueqin; Luo, Fangjun; Shi, Minlong; Wang, Long; Wang, Zhaofu; Yu, Yanyan; Zeng, Jue; Zeng, Chenhui; Zhang, Lijun; Zhang, Qiong; Zhou, Shaolian; Oyang, Counde; Atadja, Peter; Li, En 分享 收藏
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Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy Huang, Ying; Zhang, Jeff; Yu, Zhengtian; Zhang, Hailong; Wang, Youzhen; Lingel, Andreas; Qi, Wei; Gu, Justin; Zhao, Kehao; Shultz, Michael D.; Wang, Long; Fu, Xingian; Sun, Yongfeng; Zhang, Qiong; Jiang, Xiangqing; Zhang, Jiangwei; Zhang, Chunye; Li, Ling; Zeng, Jue; Feng, Lijian; Zhang, Chao; Liu, Yueqin; Zhang, Man; Zhang, Lijun; Zhao, Mengxi; Gao, Zhenting; Liu, Xianghui; Fang, Douglas; Guo, Haibing; Mi, Yuan; Gabriel, Tobias; Dillon, Michael P.; Atadja, Peter; Oyang, Counde 分享 收藏
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED Qi, Wei; Zhao, Kehao; Gu, Justin; Huang, Ying; Wang, Youzhen; Zhang, Hailong; Zhang, Man; Zhang, Jeff; Yu, Zhengtian; Li, Ling; Teng, Lin; Chuai, Shannon; Zhang, Chao; Zhao, Mengxi; Chan, Homan; Chen, Zijun; Fang, Douglas; Fei, Qi; Feng, Leying; Feng, Lijian; Gao, Yuan; Ge, Hui; Ge, Xinjian; Li, Guobin; Lingel, Andreas; Lin, Ying; Liu, Yueqin; Luo, Fangjun; Shi, Minlong; Wang, Long; Wang, Zhaofu; Yu, Yanyan; Zeng, Jue; Zeng, Chenhui; Zhang, Lijun; Zhang, Qiong; Zhou, Shaolian; Oyang, Counde; Atadja, Peter; Li, En 分享 收藏
Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase Lingel, Andreas; Sendzik, Martin; Huang, Ying; Shultz, Michael D.; Cantwell, John; Dillon, Michael P.; Fu, Xingnian; Fuller, John; Gabriel, Tobias; Gu, Justin; Jiang, Xiangqing; Li, Ling; Liang, Fang; McKenna, Maureen; Qi, Wei; Rao, Weijun; Sheng, Xijun; Shu, Wei; Sutton, James; Taft, Benjamin; Wang, Long; Zeng, Jue; Zhang, Hailong; Zhang, Maya; Zhao, Kehao; Lindvall, Mika; Bussiere, Dirksen E. 分享 收藏
A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein Gu, Xiaodong; Wu, Zhiping; Huang, Ying; Wagner, Matthew A.; Baleanu-Gogonea, Camelia; Mehl, Ryan A.; Buffa, Jennifer A.; DiDonato, Anthony J.; Hazen, Leah B.; Fox, Paul L.; Gogonea, Valentin; Parks, John S.; DiDonato, Joseph A.; Hazen, Stanley L. 分享 收藏
Interaction of β1-adrenoceptor with RAGE mediates cardiomyopathy via CaMKII signaling Zhu, Weizhong; Tsang, Sharon; Browe, David M.; Woo, Anthony Y. H.; Huang, Ying; Xu, Chanjuan; Liu, Jian-Feng; Lv, Fengxiang; Zhang, Yan; Xiao, Rui-ping 分享 收藏
Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein Interaction Gu, Xiaodong; Huang, Ying; Levison, Bruce S.; Gerstenecker, Gary; DiDonato, Anthony J.; Hazen, Leah B.; Lee, Joonsue; Gogonea, Valentin; DiDonato, Joseph A.; Hazen, Stanley L. 分享 收藏
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