Craig M. Crews - Publications, H-index & Citations

Craig M. Crews

yale university

98H指数

315论文数

4.3W被引数

收录论文 126

发表时间

The atypical E3 ligase HOIL-1 safeguards the ribosome during cellular stress 非典型E3连接酶HOIL-1在细胞应激期间保护核糖体

Nature Cell Biology

IF19.1

2026-04-01

PREAI

Douglas, Todd; Nie, Pengju; Zhang, Jiasheng; Abdallah, Kyrillos S.; Wu, Zhiping; McReynolds, Meghan; Iwai, Kazuhiro; Peng, Junmin; Gilbert, Wendy V.; Young, Lawrence H.; Crews, Craig M.

Correction: Proteolysis targeting chimeras (PROTACs) come of age: entering the third decade of targeted protein degradation 勘误：蛋白酶体靶向嵌合体（PROTACs）走向成熟：进入靶向蛋白降解的第三个十年

rsc chem. biol.

IF0

2026-01-06

OAAI

Michael J. Bond; Craig M. Crews

Quantitative Degradation Rate Assessment of bioPROTACs Based on Peptide Degrons, E3 Domains, Adapters and Conjugated Small Molecules

ACS CHEMICAL BIOLOGY

IF3.8

2026-01-01

PREAI

Vukovic, David; Winkelvoss, Dorothea; Udovcic, Anto; Riermeier, Luca; Jaime-Figueroa, Saul; Crews, Craig M.; Pluckthun, Andreas

Next steps for targeted protein degradation

CELL CHEMICAL BIOLOGY

IF7.2

2025-02-01

PREAI

Krone, Mackenzie W.; Crews, Craig M.

Development of Ligands and Degraders Targeting MAGE-A3

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-08-27

PREAI

Li, Ke; Krone, Mackenzie W.; Butrin, Arseniy; Bond, Michael J.; Linhares, Brian M.; Crews, Craig M.

EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling

SCIENCE ADVANCES

IF12.5

2024-03-29

OAAI

Hu, Zhenyi; Chen, Po-Han; Li, Wenxue; Krone, Mackenzie; Zheng, Sijin; Saarbach, Jacques; Velasco, Ines Urquizo; Hines, John; Liu, Yansheng; Crews, Craig M.

Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-02-28

PREAI

Chase, Davis H.; Bebenek, Adrian M.; Nie, Pengju; Jaime-Figueroa, Saul; Butrin, Arseniy; Castro, Danielle A.; Hines, John; Linhares, Brian M.; Crews, Craig M.

Prostate cancer RIPTAC™ therapeutics demonstrate activity in preclinical models of Enzalutamide-resistant prostate cancer

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Yu, Xinheng; Eastman, Kyle J.; Raina, Kanak; Jones, Kelli M.; Forbes, Chris D.; Hundt, Abigail; Garcia, Marco; Stronk, Rebecca; Howard, Katia; McGovern, Andrew; Chenard, Rebekka; Denny, Allison; Forgione, Mia; Bassoli, Kyle; Garvin, Ethan; Mousseau, James J.; Li, Hao; King, Madeline P.; Bhardwaj, Amit; Kayser-Bricker, Katherine J.; Crews, Craig M.

Protein degraders enter the clinic - a new approach to cancer therapy 蛋白质降解剂进入临床-癌症治疗的新方法

NATURE REVIEWS CLINICAL ONCOLOGY

IF82.2

2023-02-13

210

PREAI

Chirnomas, Deborah; Hornberger, Keith R.; Crews, Craig M.

Targeted Dephosphorylation of Tau by Phosphorylation Targeting Chimeras (PhosTACs) as a Therapeutic Modality 磷酸化靶向嵌合体 (PhosTACs) 靶向Tau去磷酸化作为治疗方式

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-02-08

PREAI

Hu, Zhenyi; Chen, Po-Han; Li, Wenxue; Douglas, Todd; Hines, John; Liu, Yansheng; Crews, Craig M.

Life mimics art

CELL RESEARCH

IF25.9

2023-01-16

OAAI

Venkatachalapathy, Muthukumaran; Crews, Craig M.

Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC

ACS CHEMICAL BIOLOGY

IF3.8

2022-06-24

OAAI

Swartzel, Jake C.; Bond, Michael J.; Pintado-Urbanc, Andreas P.; Daftary, Mehana; Krone, Mackenzie W.; Douglas, Todd; Carder, Evan J.; Zimmer, Joshua T.; Maeda, Takahiro; Simon, Matthew D.; Crews, Craig M.

Hijacking Methyl Reader Proteins for Nuclear-Specific Protein Degradation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-03-21

OAAI

Nalawansha, Dhanusha A.; Li, Ke; Hines, John; Crews, Craig M.

PROTAC targeted protein degraders: the past is prologue PROTAC靶向蛋白质降解剂: 过去是序幕

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2022-01-18

1.4K

OAAI

Bekes, Miklos; Langley, David R.; Crews, Craig M.

OligoTRAFTACs: A generalizable method for transcription factor degradation

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-01

OAAI

Samarasinghe, Kusal T. G.; An, Elvira; Genuth, Miriam A.; Chu, Ling; Holley, Scott A.; Crews, Craig M.

Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)

ACS CHEMICAL BIOLOGY

IF3.8

2021-11-15

OAAI

Chen, Po-Han; Hu, Zhenyi; An, Elvira; Okeke, Ifunanya; Zheng, Sijin; Luo, Xuanmeng; Gong, Angela; Jaime-Figueroa, Saul; Crews, Craig M.

Targeted protein degradation: A promise for undruggable proteins

CELL CHEMICAL BIOLOGY

IF7.2

2021-07-01

164

OAAI

Samarasinghe, Kusal T. G.; Crews, Craig M.

Synthesis of Isoquinolones by Sequential Suzuki Coupling of 2-Halobenzonitriles with Vinyl Boronate Followed by Cyclization

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2021-05-28

PREAI

Jaime-Figueroa, Saul; Bond, Michael J.; Vergara, J. Ignacio; Swartzel, Jake C.; Crews, Craig M.

Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras

CELL CHEMICAL BIOLOGY

IF7.2

2021-05-01

114

OAAI

Samarasinghe, Kusal T. G.; Jaime-Figueroa, Saul; Burgess, Michael; Nalawansha, Dhanusha A.; Dai, Katherine; Hu, Zhenyi; Bebenek, Adrian; Holley, Scott A.; Crews, Craig M.

BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma

LEUKEMIA

IF13.4

2021-03-02

OAAI

Fiskus, Warren; Mill, Christopher P.; Perera, Dimuthu; Birdwell, Christine; Deng, Qing; Yang, Haopeng; Lara, Bernardo H.; Jain, Nitin; Burger, Jan; Ferrajoli, Alessandra; Davis, John A.; Saenz, Dyana T.; Jin, Wendy; Coarfa, Cristian; Crews, Craig M.; Green, Michael R.; Khoury, Joseph D.; Bhalla, Kapil N.

研究方向