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A

Asaf Rotem

astrazeneca
H指数:28
被引数:1.2万

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A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma

TP53相关的组织重塑细胞和空间图谱定义了肺腺癌中的多细胞肿瘤生态系统

Nature Cancer
IF28.5
2025-10-070
PRE
William Zhao; Thinh T. Nguyen; Atharva Bhagwat; Akhil Kumar; Bruno Giotti; Benjamin Kepecs; Jason L. Weirather; Navin R. Mahadevan; Asa Segerstolpe; Komal Dolasia; Jamshid Abdul-Ghafar; Naomi R. Besson; Stephanie M. Jones; Brian Y. Soong; Chendi Li; Sebastien Vigneau; Michal Slyper; Isaac Wakiro; Mei-Ju Su; Karla Helvie; Allison Frangieh; Judit Jane-Valbuena; Orr Ashenberg; Mark Awad; Asaf Rotem; Raphael Bueno; Orit Rozenblatt-Rosen; Kathleen Pfaff; Scott Rodig; Aaron N. Hata; Aviv Regev; Bruce E. Johnson; Alexander M. Tsankov
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

跨临床病理特征的转移性乳腺癌活检的多模态单细胞和空间表达图

NATURE MEDICINE
IF50
2024-10-301
OAAI
Klughammer, Johanna; Abravanel, Daniel L.; Segerstolpe, Asa; Blosser, Timothy R.; Goltsev, Yury; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Ashenberg, Orr; Slyper, Michal; Vigneau, Sebastien; Jane-Valbuena, Judit; Alon, Shahar; Caraccio, Chiara; Chen, Judy; Cohen, Ofir; Cullen, Nicole; DelloStritto, Laura K.; Dionne, Danielle; Files, Janet; Frangieh, Allison; Helvie, Karla; Hughes, Melissa E.; Inga, Stephanie; Kanodia, Abhay; Lako, Ana; MacKichan, Colin; Mages, Simon; Moriel, Noa; Murray, Evan; Napolitano, Sara; Nguyen, Kyleen; Nitzan, Mor; Ortiz, Rebecca; Patel, Miraj; Pfaff, Kathleen L.; Porter, Caroline B. M.; Rotem, Asaf; Strauss, Sarah; Strasser, Robert; Thorner, Aaron R.; Turner, Madison; Wakiro, Isaac; Waldman, Julia; Wu, Jingyi; Zanudo, Jorge Gomez Tejeda; Zhang, Diane; Lin, Nancy U.; Tolaney, Sara M.; Winer, Eric P.; Boyden, Edward S.; Chen, Fei; Nolan, Garry P.; Rodig, Scott J.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Liquid biopsy tracking of immunotherapy-induced T cell dynamics in MSS colorectal and endometrial tumors

液体活检追踪免疫疗法诱导的T细胞动态变化在微卫星稳定性结直肠癌和子宫内膜肿瘤中的作用

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Heyn, H.; Melero, J. L.; Deuner, G.; Baraibar Argota, I.; Grzelak, M.; Caratu, G.; Garcia Duran, C.; Grau Bejar, J. F.; Illescas, D. G.; Farinas Madrid, L.; Nieto, P.; Morabito, S.; Rotem, A.; Casbas-Hernandez, P.; Gros, A.; Tabernero, J.; Oaknin, A.; Sachica, J. N.; Borcherding, N.; Elez Fernandez, M. E.
Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors
SCIENCE ADVANCES
IF12.5
2023-09-294
OAAI
Hoffman, Samantha E.; Dowrey, Todd W.; Villacorta Martin, Carlos; Bi, Kevin; Titchen, Breanna; Johri, Shreya; Dellostritto, Laura; Patel, Miraj; Mackichan, Colin; Inga, Stephanie; Chen, Judy; Grimaldi, Grace; Napolitano, Sara; Wakiro, Isaac; Wu, Jingyi; Yeung, Jason; Rotem, Asaf; Sicinska, Ewa; Shannon, Erin; Clancy, Thomas; Wang, Jiping; Denning, Sarah; Brais, Lauren; Besson, Naomi R.; Pfaff, Kathleen L.; Huang, Ying; Kao, Katrina Z.; Rodig, Scott; Hornick, Jason L.; Vigneau, Sebastien; Park, Jihye; Kulke, Matthew H.; Chan, Jennifer; Van Allen, Eliezer M.; Murphy, George J.
Spatio-molecular dissection of the breast cancer metastatic microenvironment
CANCER RESEARCH
IF16.6
2022-02-150
PRE
Abravanel, Daniel L.; Klughammer, Johanna; Blosser, Timothy; Goltsev, Yury; Jiang, Sizun; Bai, Yunjao; Murray, Evan; Alon, Shahar; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Cohen, Ofir; Slyper, Michal; Ashenberg, Orr; Dionne, Danielle; Jane-Valbuena, Judit; Porter, Caroline BM.; Segerstolpe, Asa; Waldman, Julia; Vigneau, Sebastien; Helvie, Karla; Frangieh, Allison; DelloStritto, Laura; Patel, Miraj; We, Jingyi; Pfaff, Kathleen; Cullen, Nicole; Lako, Ana; Turner, Madison; Wakiro, Isaac; Napolitano, Sara; Kanodia, Abhay; Ortiz, Rebecca; MacKichan, Colin; Inga, Stephanie; Chen, Judy; Thorner, Aaron R.; Rotem, Asaf; Rodig, Scott; Chen, Fei; Boyden, Edward S.; Nolan, Garry P.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Transcriptional mediators of treatment resistance in lethal prostate cancer
NATURE MEDICINE
IF50
2021-03-04101
OAAI
He, Meng Xiao; Cuoco, Michael S.; Crowdis, Jett; Bosma-Moody, Alice; Zhang, Zhenwei; Bi, Kevin; Kanodia, Abhay; Su, Mei-Ju; Ku, Sheng-Yu; Garcia, Maria Mica; Sweet, Amalia R.; Rodman, Christopher; DelloStritto, Laura; Silver, Rebecca; Steinharter, John; Shah, Parin; Izar, Benjamin; Walk, Nathan C.; Burke, Kelly P.; Bakouny, Ziad; Tewari, Alok K.; Liu, David; Camp, Sabrina Y.; Vokes, Natalie I.; Salari, Keyan; Park, Jihye; Vigneau, Sebastien; Fong, Lawrence; Russo, Joshua W.; Yuan, Xin; Balk, Steven P.; Beltran, Himisha; Rozenblatt-Rosen, Orit; Regev, Aviv; Rotem, Asaf; Taplin, Mary-Ellen; Van Allen, Eliezer M.
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

患者模型中的多模式混合扰动-cite-seq筛选定义了癌症免疫逃避的机制

NATURE GENETICS
IF31.8
2021-03-01132
OAAI
Frangieh, Chris J.; Melms, Johannes C.; Thakore, Pratiksha, I; Geiger-Schuller, Kathryn R.; Ho, Patricia; Luoma, Adrienne M.; Cleary, Brian; Jerby-Arnon, Livnat; Malu, Shruti; Cuoco, Michael S.; Zhao, Maryann; Ager, Casey R.; Rogava, Meri; Hovey, Lila; Rotem, Asaf; Bernatchez, Chantale; Wucherpfennig, Kai W.; Johnson, Bruce E.; Rozenblatt-Rosen, Orit; Schadendorf, Dirk; Regev, Aviv; Izar, Benjamin
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (vol 26, pg 792, 2020)
NATURE MEDICINE
IF50
2020-06-2515
OAAI
Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Nguyen Lan; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv
A single-cell landscape of high-grade serous ovarian cancer
NATURE MEDICINE
IF50
2020-06-22302
OAAI
Izar, Benjamin; Tirosh, Itay; Stover, Elizabeth H.; Wakiro, Isaac; Cuoco, Michael S.; Alter, Idan; Rodman, Christopher; Leeson, Rachel; Su, Mei-Ju; Shah, Parin; Iwanicki, Marcin; Walker, Sarah R.; Kanodia, Abhay; Melms, Johannes C.; Mei, Shaolin; Lin, Jia-Ren; Porter, Caroline B. M.; Slyper, Michal; Waldman, Julia; Jerby-Arnon, Livnat; Ashenberg, Orr; Brinker, Titus J.; Mills, Caitlin; Rogava, Meri; Vigneau, Sebastien; Sorger, Peter K.; Garraway, Levi A.; Konstantinopoulos, Panagiotis A.; Liu, Joyce F.; Matulonis, Ursula; Johnson, Bruce E.; Rozenblatt-Rosen, Orit; Rotem, Asaf; Regev, Aviv
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
NATURE MEDICINE
IF50
2020-05-11400
OAAI
Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Lan Nguyen; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv
A joint atlas of single-cell and bulk RNA-seq in metastatic breast cancer allows inference of oncogenic and drug-resistant transcriptional programs in malignant cells and the tumor microenvironment
CANCER RESEARCH
IF16.6
2020-02-150
PRE
Cohen, Ofir; Abravanel, Daniel; Slyper, Michal; Klughammer, Johanna; Jane-Valbuena, Judit; Helvie, Karla; Dellostritto, Laura; Frangieh, Allison; Vigneau, Sebastien; Wu, Jingyi; Mayorga, Angie; Waldman, Julia; Nguyen, Lan; Dionne, Danielle; Ashenberg, Orr; Hofree, Matan; Cuoco, Mike; Rodman, Christopher; Winer, Eric P.; Lin, Nancy; Johnson, Bruce; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv; Wagle, Nikhil
Development of therapeutic strategies by resolving the tumor ecosystem
CANCER RESEARCH
IF16.6
2019-07-010
PRE
Izar, Benjamin; Jerby-Arnon, Livnat; Tirosh, Itay; Shah, Parin; Cuoco, Michael C.; Rodman, Christopher; Su, Mei-Ju; Melms, Johannes C.; Leeson, Rachel; Kanodia, Abhay; Lin, Jia-Ren; Boland, Genevieve M.; Zhang, Gao; Hodi, F. Stephen; Sorger, Peter K.; Wucherpfennig, Kai W.; Van Allen, Eli M.; Schadendorf, Dirk; Rozenblatt-Rosen, Orit; Garraway, Levi A.; Rotem, Asaf; Yoon, Charles H.; Regev, Aviv
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
CANCER DISCOVERY
IF33.3
2018-02-04404
OAAI
Jenkins, Russell W.; Aref, Amir R.; Lizotte, Patrick H.; Ivanova, Elena; Stinson, Susanna; Zhou, Chensheng W.; Bowden, Michaela; Deng, Jiehui; Liu, Hongye; Miao, Diana; He, Meng Xiao; Walker, William; Zhang, Gao; Tian, Tian; Cheng, Chaoran; Wei, Zhi; Palakurthi, Sangeetha; Bittinger, Mark; Vitzthum, Hans; Kim, Jong Wook; Merlino, Ashley; Quinn, Max; Venkataramani, Chandrasekar; Kaplan, Joshua A.; Portell, Andrew; Gokhale, Prafulla C.; Phillips, Bart; Smart, Alicia; Rotem, Asaf; Jones, Robert E.; Keogh, Lauren; Anguiano, Maria; Stapleton, Lance; Jia, Zhiheng; Barzily-Rokni, Michal; Canadas, Israel; Thai, Tran C.; Hammond, Marc R.; Vlahos, Raven; Wang, Eric S.; Zhang, Hua; Li, Shuai; Hanna, Glenn J.; Huang, Wei; Hoang, Mai P.; Piris, Adriano; Eliane, Jean-Pierre; Stemmer-Rachamimov, Anat O.; Cameron, Lisa; Su, Mei-Ju; Shah, Parin; Izar, Benjamin; Thakuria, Manisha; LeBoeuf, Nicole R.; Rabinowits, Guilherme; Gunda, Viswanath; Parangi, Sareh; Cleary, James M.; Miller, Brian C.; Kitajima, Shunsuke; Thummalapalli, Rohit; Miao, Benchun; Barbie, Thanh U.; Sivathanu, Vivek; Wong, Joshua; Richards, William G.; Bueno, Raphael; Yoon, Charles H.; Miret, Juan; Herlyn, Meenhard; Garraway, Levi A.; Van Allen, Eliezer M.; Freeman, Gordon J.; Kirschmeier, Paul T.; Lorch, Jochen H.; Ott, Patrick A.; Hodi, F. Stephen; Flaherty, Keith T.; Kamm, Roger D.; Boland, Genevieve M.; Wong, Kwok-Kin; Dornan, David; Paweletz, Cloud Peter; Barbie, David A.

研究方向

暂未获取到该数据
B
Benjamin Izar
H 指数:46论文数:292被引数:1.8万
A
Aviv Regev
H 指数:208论文数:999被引数:22.4万
O
Orit Rozenblatt–Rosen
H 指数:95论文数:259被引数:5.7万
S
Sébastien Vigneau
H 指数:26论文数:84被引数:5,371
L
Levi A. Garraway
H 指数:147论文数:1,018被引数:14.8万
B
Bruce E. Johnson
H 指数:123论文数:1,090被引数:8.7万
M
Michal Slyper
H 指数:29论文数:93被引数:1.0万
J
Judit Jané‐Valbuena
H 指数:28论文数:74被引数:2.4万
I
Isaac Wakiro
H 指数:11论文数:43被引数:2,928
J
Julia Waldman
H 指数:25论文数:64被引数:8,030