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S

Sébastien Vigneau

Dana-Farber Cancer Institute
H指数:26
被引数:5,376

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Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss

单细胞表观遗传图谱揭示了一种与不良预后和BAP1缺失相关的ccRCC肿瘤内干扰素应答程序。

Science Advances
IF12.5
2026-02-200
OA
Sabrina Y. Camp; Meng Xiao He; Michael S. Cuoco; Amanda E. Garza; Sherin Xirenayi; Ziad Bakouny; Eddy Saad; Jad El Masri; Erica Pimenta; Kevin Meli; Chris Labaki; Breanna M. Titchen; Yun Jee Kang; Jack Horst; Rachel Trowbridge; Erin Shannon; Karla Helvie; Aaron R. Thorner; Sébastien Vigneau; Angie Mayorga; Jahnavi Kodali; Hannah Lachmayr; Meredith Bemus; Pengsheng Chen; Haiteng Deng; Jihye Park; Toni K. Choueiri; Kevin Bi; Eliezer M. Van Allen
Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer

早期激素受体阳性乳腺癌在抗PD-1和化疗治疗期间细胞的重编程

Nature Communications
IF15.7
2025-11-280
OAAI
Jingxin Fu; Adrienne G. Waks; Erica Pimenta; Breanna Titchen; Kevin Bi; Sabrina Camp; Theodora Pappa; Tanya Keenan; Erin Shannon; Sébastien Vigneau; Meredith Bemus; Anwesha Nag; Aaron R. Thorner; Jihye Park; Molly DiLullo; Eileen Wrabel; Rinath Jeselsohn; Elizabeth A. Mittendorf; Daniel L. Abravanel; Sara M. Tolaney; Eliezer M. Van Allen
A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma

TP53相关的组织重塑细胞和空间图谱定义了肺腺癌中的多细胞肿瘤生态系统

Nature Cancer
IF28.5
2025-10-070
PRE
William Zhao; Thinh T. Nguyen; Atharva Bhagwat; Akhil Kumar; Bruno Giotti; Benjamin Kepecs; Jason L. Weirather; Navin R. Mahadevan; Asa Segerstolpe; Komal Dolasia; Jamshid Abdul-Ghafar; Naomi R. Besson; Stephanie M. Jones; Brian Y. Soong; Chendi Li; Sebastien Vigneau; Michal Slyper; Isaac Wakiro; Mei-Ju Su; Karla Helvie; Allison Frangieh; Judit Jane-Valbuena; Orr Ashenberg; Mark Awad; Asaf Rotem; Raphael Bueno; Orit Rozenblatt-Rosen; Kathleen Pfaff; Scott Rodig; Aaron N. Hata; Aviv Regev; Bruce E. Johnson; Alexander M. Tsankov
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

跨临床病理特征的转移性乳腺癌活检的多模态单细胞和空间表达图

NATURE MEDICINE
IF50
2024-10-301
OAAI
Klughammer, Johanna; Abravanel, Daniel L.; Segerstolpe, Asa; Blosser, Timothy R.; Goltsev, Yury; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Ashenberg, Orr; Slyper, Michal; Vigneau, Sebastien; Jane-Valbuena, Judit; Alon, Shahar; Caraccio, Chiara; Chen, Judy; Cohen, Ofir; Cullen, Nicole; DelloStritto, Laura K.; Dionne, Danielle; Files, Janet; Frangieh, Allison; Helvie, Karla; Hughes, Melissa E.; Inga, Stephanie; Kanodia, Abhay; Lako, Ana; MacKichan, Colin; Mages, Simon; Moriel, Noa; Murray, Evan; Napolitano, Sara; Nguyen, Kyleen; Nitzan, Mor; Ortiz, Rebecca; Patel, Miraj; Pfaff, Kathleen L.; Porter, Caroline B. M.; Rotem, Asaf; Strauss, Sarah; Strasser, Robert; Thorner, Aaron R.; Turner, Madison; Wakiro, Isaac; Waldman, Julia; Wu, Jingyi; Zanudo, Jorge Gomez Tejeda; Zhang, Diane; Lin, Nancy U.; Tolaney, Sara M.; Winer, Eric P.; Boyden, Edward S.; Chen, Fei; Nolan, Garry P.; Rodig, Scott J.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors
SCIENCE ADVANCES
IF12.5
2023-09-294
OAAI
Hoffman, Samantha E.; Dowrey, Todd W.; Villacorta Martin, Carlos; Bi, Kevin; Titchen, Breanna; Johri, Shreya; Dellostritto, Laura; Patel, Miraj; Mackichan, Colin; Inga, Stephanie; Chen, Judy; Grimaldi, Grace; Napolitano, Sara; Wakiro, Isaac; Wu, Jingyi; Yeung, Jason; Rotem, Asaf; Sicinska, Ewa; Shannon, Erin; Clancy, Thomas; Wang, Jiping; Denning, Sarah; Brais, Lauren; Besson, Naomi R.; Pfaff, Kathleen L.; Huang, Ying; Kao, Katrina Z.; Rodig, Scott; Hornick, Jason L.; Vigneau, Sebastien; Park, Jihye; Kulke, Matthew H.; Chan, Jennifer; Van Allen, Eliezer M.; Murphy, George J.
Spatio-molecular dissection of the breast cancer metastatic microenvironment
CANCER RESEARCH
IF16.6
2022-02-150
PRE
Abravanel, Daniel L.; Klughammer, Johanna; Blosser, Timothy; Goltsev, Yury; Jiang, Sizun; Bai, Yunjao; Murray, Evan; Alon, Shahar; Cui, Yi; Goodwin, Daniel R.; Sinha, Anubhav; Cohen, Ofir; Slyper, Michal; Ashenberg, Orr; Dionne, Danielle; Jane-Valbuena, Judit; Porter, Caroline BM.; Segerstolpe, Asa; Waldman, Julia; Vigneau, Sebastien; Helvie, Karla; Frangieh, Allison; DelloStritto, Laura; Patel, Miraj; We, Jingyi; Pfaff, Kathleen; Cullen, Nicole; Lako, Ana; Turner, Madison; Wakiro, Isaac; Napolitano, Sara; Kanodia, Abhay; Ortiz, Rebecca; MacKichan, Colin; Inga, Stephanie; Chen, Judy; Thorner, Aaron R.; Rotem, Asaf; Rodig, Scott; Chen, Fei; Boyden, Edward S.; Nolan, Garry P.; Zhuang, Xiaowei; Rozenblatt-Rosen, Orit; Johnson, Bruce E.; Regev, Aviv; Wagle, Nikhil
Transcriptional mediators of treatment resistance in lethal prostate cancer
NATURE MEDICINE
IF50
2021-03-04101
OAAI
He, Meng Xiao; Cuoco, Michael S.; Crowdis, Jett; Bosma-Moody, Alice; Zhang, Zhenwei; Bi, Kevin; Kanodia, Abhay; Su, Mei-Ju; Ku, Sheng-Yu; Garcia, Maria Mica; Sweet, Amalia R.; Rodman, Christopher; DelloStritto, Laura; Silver, Rebecca; Steinharter, John; Shah, Parin; Izar, Benjamin; Walk, Nathan C.; Burke, Kelly P.; Bakouny, Ziad; Tewari, Alok K.; Liu, David; Camp, Sabrina Y.; Vokes, Natalie I.; Salari, Keyan; Park, Jihye; Vigneau, Sebastien; Fong, Lawrence; Russo, Joshua W.; Yuan, Xin; Balk, Steven P.; Beltran, Himisha; Rozenblatt-Rosen, Orit; Regev, Aviv; Rotem, Asaf; Taplin, Mary-Ellen; Van Allen, Eliezer M.
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors (vol 26, pg 792, 2020)
NATURE MEDICINE
IF50
2020-06-2515
OAAI
Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Nguyen Lan; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv
A single-cell landscape of high-grade serous ovarian cancer
NATURE MEDICINE
IF50
2020-06-22302
OAAI
Izar, Benjamin; Tirosh, Itay; Stover, Elizabeth H.; Wakiro, Isaac; Cuoco, Michael S.; Alter, Idan; Rodman, Christopher; Leeson, Rachel; Su, Mei-Ju; Shah, Parin; Iwanicki, Marcin; Walker, Sarah R.; Kanodia, Abhay; Melms, Johannes C.; Mei, Shaolin; Lin, Jia-Ren; Porter, Caroline B. M.; Slyper, Michal; Waldman, Julia; Jerby-Arnon, Livnat; Ashenberg, Orr; Brinker, Titus J.; Mills, Caitlin; Rogava, Meri; Vigneau, Sebastien; Sorger, Peter K.; Garraway, Levi A.; Konstantinopoulos, Panagiotis A.; Liu, Joyce F.; Matulonis, Ursula; Johnson, Bruce E.; Rozenblatt-Rosen, Orit; Rotem, Asaf; Regev, Aviv
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
NATURE MEDICINE
IF50
2020-05-11400
OAAI
Slyper, Michal; Porter, Caroline B. M.; Ashenberg, Orr; Waldman, Julia; Drokhlyansky, Eugene; Wakiro, Isaac; Smillie, Christopher; Smith-Rosario, Gabriela; Wu, Jingyi; Dionne, Danielle; Vigneau, Sebastien; Jane-Valbuena, Judit; Tickle, Timothy L.; Napolitano, Sara; Su, Mei-Ju; Patel, Anand G.; Karlstrom, Asa; Gritsch, Simon; Nomura, Masashi; Waghray, Avinash; Gohil, Satyen H.; Tsankov, Alexander M.; Jerby-Arnon, Livnat; Cohen, Ofir; Klughammer, Johanna; Rosen, Yanay; Gould, Joshua; Lan Nguyen; Hofree, Matan; Tramontozzi, Peter J.; Li, Bo; Wu, Catherine J.; Izar, Benjamin; Haq, Rizwan; Hodi, F. Stephen; Yoon, Charles H.; Hata, Aaron N.; Baker, Suzanne J.; Suva, Mario L.; Bueno, Raphael; Stover, Elizabeth H.; Clay, Michael R.; Dyer, Michael A.; Collins, Natalie B.; Matulonis, Ursula A.; Wagle, Nikhil; Johnson, Bruce E.; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv
A joint atlas of single-cell and bulk RNA-seq in metastatic breast cancer allows inference of oncogenic and drug-resistant transcriptional programs in malignant cells and the tumor microenvironment
CANCER RESEARCH
IF16.6
2020-02-150
PRE
Cohen, Ofir; Abravanel, Daniel; Slyper, Michal; Klughammer, Johanna; Jane-Valbuena, Judit; Helvie, Karla; Dellostritto, Laura; Frangieh, Allison; Vigneau, Sebastien; Wu, Jingyi; Mayorga, Angie; Waldman, Julia; Nguyen, Lan; Dionne, Danielle; Ashenberg, Orr; Hofree, Matan; Cuoco, Mike; Rodman, Christopher; Winer, Eric P.; Lin, Nancy; Johnson, Bruce; Rotem, Asaf; Rozenblatt-Rosen, Orit; Regev, Aviv; Wagle, Nikhil

研究方向

暂未获取到该数据
A
Asaf Rotem
H 指数:28论文数:140被引数:1.2万
B
Bruce E. Johnson
H 指数:123论文数:1,090被引数:8.7万
A
Aviv Regev
H 指数:208论文数:999被引数:22.4万
O
Orit Rozenblatt–Rosen
H 指数:95论文数:259被引数:5.7万
M
Michal Slyper
H 指数:29论文数:93被引数:1.0万
I
Isaac Wakiro
H 指数:11论文数:43被引数:2,931
J
Julia Waldman
H 指数:25论文数:64被引数:8,033
J
Judit Jané‐Valbuena
H 指数:28论文数:74被引数:2.4万
D
Danielle Dionne
H 指数:41论文数:101被引数:2.3万
O
Ofir Cohen
H 指数:42论文数:264被引数:1.4万