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Contribution of intact viral genomes persisting in blood and tissues during ART to plasma viral rebound in SHIV-infected rhesus macaques 在ART治疗期间，持续存在于血液和组织中的完整病毒基因组对SHIV感染恒河猴血浆病毒反弹的贡献 Trifone, Cesar; Richard, Corentin; Pagliuzza, Amelie; Dufour, Caroline; Lemieux, Audree; Clark, Natasha M.; Janaka, Sanath K.; Fennessey, Christine M.; Keele, Brandon E.; Fromentin, Remi; Estes, Jacob D.; Kaufmann, Daniel E.; Finzi, Andres; Evans, David T.; Chomont, Nicolas 分享 收藏
IL-32 Drives the Differentiation of Cardiotropic CD4+ T Cells Carrying HIV DNA in People With HIV Ramani, Hardik; Gosselin, Annie; Bunet, Remi; Jenabian, Mohammad-Ali; Sylla, Mohamed; Pagliuzza, Amelie; Chartrand-Lefebvre, Carl; Routy, Jean-Pierre; Goulet, Jean-Philippe; Thomas, Rejean; Trottier, Benoit; Martel-Laferriere, Valerie; Fortin, Claude; Chomont, Nicolas; Fromentin, Remi; Landay, Alan L.; Durand, Madeleine; Ancuta, Petronela; El-Far, Mohamed; Tremblay, Cecile 分享 收藏
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia Benlarbi, Mehdi; Richard, Jonathan; Bourassa, Catherine; Tolbert, William D.; Chartrand-Lefebvre, Carl; Gendron-Lepage, Gabrielle; Sylla, Mohamed; El-Far, Mohamed; Messier-Peet, Marc; Guertin, Camille; Turcotte, Isabelle; Fromentin, Remi; Verly, Myriam Maude; Prevost, Jeremie; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Maldarelli, Frank; Chomont, Nicolas; Begin, Philippe; Tremblay, Cecile; Baril, Jean-Guy; Trottier, Benoit; Trottier, Sylvie; Duerr, Ralf; Pazgier, Marzena; Durand, Madeleine; Finzi, Andres 分享 收藏
CD8+ T-cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy 在接受抗逆转录病毒治疗的HIV-1患者中，CD8 T细胞启动在数量上受损，但在质量上没有受损 Cabral-Piccin, Mariela P.; Briceno, Olivia; Papagno, Laura; Liouville, Benjamin; White, Eoghann; Perdomo-Celis, Federico; Autaa, Gaelle; Volant, Stevenn; Llewellyn-Lacey, Sian; Fromentin, Remi; Chomont, Nicolas; Price, David A.; Saez-Cirion, Asier; Lambotte, Olivier; Katlama, Christine; Appay, Victor 分享 收藏
Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART 尸检后收集的多个组织中的近全长HIV测序揭示了ART期间跨不同水库的共享克隆扩张 Dufour, Caroline; Ruiz, Maria Julia; Pagliuzza, Amelie; Richard, Corentin; Shahid, Aniqa; Fromentin, Remi; Ponte, Rosalie; Cattin, Amelie; Salinas, Tomas Raul Wiche; Salahuddin, Syim; Sandstrom, Teslin; Schinkel, Stephanie Burke; Costiniuk, Cecilia T.; Jenabian, Mohammad-Ali; Ancuta, Petronela; Routy, Jean-Pierre; Cohen, Eric A.; Brumme, Zabrina L.; Power, Christopher; Angel, Jonathan B.; Chomont, Nicolas 分享 收藏
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HIV rapidly targets a diverse pool of CD4+T cells to establish productive and latent infections Gantner, Pierre; Buranapraditkun, Supranee; Pagliuzza, Amelie; Dufour, Caroline; Pardons, Marion; Mitchell, Julie L.; Kroon, Eugene; Sacdalan, Carlo; Tulmethakaan, Nicha; Pinyakorn, Suteeraporn; Robb, Merlin L.; Phanuphak, Nittaya; Ananworanich, Jintanat; Hsu, Denise; Vasan, Sandhya; Trautmann, Lydie; Fromentin, Remi; Chomont, Nicolas 分享 收藏
Phenotypic characterization of single CD4+T cells harboring genetically intact and inducible HIV genomes Dufour, Caroline; Richard, Corentin; Pardons, Marion; Massanella, Marta; Ackaoui, Antoine; Murrell, Ben; Routy, Bertrand; Thomas, Rejean; Routy, Jean-Pierre; Fromentin, Remi; Chomont, Nicolas 分享 收藏
Association Between the Development of Subclinical Cardiovascular Disease and Human Immunodeficiency Virus (HIV) Reservoir Markers in People With HIV on Suppressive Antiretroviral Therapy Turcotte, Isabelle; El-Far, Mohamed; Sadouni, Manel; Chartrand-Lefebvre, Carl; Filali-Mouhim, Ali; Fromentin, Remi; Chamberland, Annie; Jenabian, Mohammad-Ali; Baril, Jean-Guy; Trottier, Benoit; Thomas, Rejean; Tremblay, Cecile L.; Durand, Madeleine; Chomont, Nicolas; Canadian HIV Aging Cohort Study 分享 收藏
Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency Rasmussen, Thomas A.; Zerbato, Jennifer M.; Rhodes, Ajantha; Tumpach, Carolin; Dantanarayana, Ashanti; McMahon, James H.; Lau, Jillian S. Y.; Chang, J. Judy; Gubser, Celine; Brown, Wendy; Hoh, Rebecca; Krone, Melissa; Pascoe, Rachel; Chiu, Chris Y.; Bramhall, Michael; Lee, Hyun Jae; Haque, Ashraful; Fromentin, Remi; Chomont, Nicolas; Milush, Jeffrey; Van der Sluis, Renee M.; Palmer, Sarah; Deeks, Steven G.; Cameron, Paul U.; Evans, Vanessa; Lewin, Sharon R. 分享 收藏
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy Uldrick, Thomas S.; Adams, Scott, V; Fromentin, Remi; Roche, Michael; Fling, Steven P.; Goncalves, Priscila H.; Lurain, Kathryn; Ramaswami, Ramya; Wang, Chia-Ching Jackie; Gorelick, Robert J.; Welker, Jorden L.; O'Donoghue, Liz; Choudhary, Harleen; Lifson, Jeffrey D.; Rasmussen, Thomas A.; Rhodes, Ajantha; Tumpach, Carolin; Yarchoan, Robert; Maldarelli, Frank; Cheever, Martin A.; Sekaly, Rafick; Chomont, Nicolas; Deeks, Steven G.; Lewin, Sharon R. 分享 收藏
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription Okoye, Afam A.; Fromentin, Remi; Takata, Hiroshi; Brehm, Jessica H.; Fukazawa, Yoshinori; Randall, Bryan; Pardons, Marion; Tai, Vincent; Tang, Jun; Smedley, Jeremy; Axthelm, Michael; Lifson, Jeffrey D.; Picker, Louis J.; Favre, David; Trautmann, Lydie; Chomont, Nicolas 分享 收藏
Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy Chiu, Chris Y.; Chang, Judy J.; Dantanarayana, Ashanti, I; Solomon, Ajantha; Evans, Vanessa A.; Pascoe, Rachel; Gubser, Celine; Trautman, Lydie; Fromentin, Remi; Chomont, Nicolas; McMahon, James H.; Cameron, Paul U.; Rasmussen, Thomas A.; Lewin, Sharon R. 分享 收藏
Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality Brunet-Ratnasingham, Elsa; Anand, Sai Priya; Gantner, Pierre; Dyachenko, Alina; Moquin-Beaudry, Gael; Brassard, Nathalie; Beaudoin-Bussieres, Guillaume; Pagliuzza, Amelie; Gasser, Romain; Benlarbi, Mehdi; Point, Floriane; Prevost, Jeremie; Laumaea, Annemarie; Niessl, Julia; Nayrac, Manon; Sannier, Geremy; Orban, Catherine; Messier-Peet, Marc; Butler-Laporte, Guillaume; Morrison, David R.; Zhou, Sirui; Nakanishi, Tomoko; Boutin, Marianne; Descoteaux-Dinelle, Jade; Gendron-Lepage, Gabrielle; Goyette, Guillaume; Bourassa, Catherine; Medjahed, Halima; Laurent, Laetitia; Rebillard, Rose-Marie; Richard, Jonathan; Dube, Mathieu; Fromentin, Remi; Arbour, Nathalie; Prat, Alexandre; Larochelle, Catherine; Durand, Madeleine; Richards, J. Brent; Chasse, Michael; Tetreault, Martine; Chomont, Nicolas; Finzi, Andres; Kaufmann, Daniel E. 分享 收藏
Combined single-cell transcriptional, translational, and genomic profiling reveals HIV-1 reservoir diversity Sannier, Geremy; Dube, Mathieu; Dufour, Caroline; Richard, Corentin; Brassard, Nathalie; Delgado, Gloria-Gabrielle; Pagliuzza, Amelie; Baxter, Amy E.; Niessl, Julia; Brunet-Ratnasingham, Elsa; Charlebois, Roxanne; Routy, Bertrand; Routy, Jean-Pierre; Fromentin, Remi; Chomont, Nicolas; Kaufmann, Daniel E. 分享 收藏
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Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time 随着时间的推移，细胞激活，分化和增殖会影响遗传完整的原病毒的动力学 Horsburgh, Bethany A.; Hiener, Bonnie; Fisher, Katie; Lee, Eunok; Morgan, Hannah; Eden, John-Sebastian; von Stockenstrom, Susanne; Odevall, Lina; Milush, Jeffrey M.; Hoh, Rebecca; Fromentin, Remi; Chomont, Nicolas; Hecht, Frederick M.; Schlub, Timothy E.; Deeks, Steven G.; Palmer, Sarah 分享 收藏
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