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A phase 1 study of the combination of BH3-mimetic, navitoclax, and mTORC1/2 inhibitor, vistusertib, in patients with advanced solid tumors 一项关于BH3-mimetic（navitoclax）与mTORC1/2抑制剂（vistusertib）联合治疗晚期实体瘤患者的I期研究 Scott, Susan C.; Farago, Anna; Lai, W. Victoria; Zahurak, Marianna; Rudek, Michelle A.; Murray, Judy; Carducci, Michael A.; Uziel, Tamar; Takebe, Naoko; Gore, Steven D.; Rudin, Charles M.; Hann, Christine L. 分享 收藏
First-line Osimertinib for Lung Cancer With Uncommon EGFR Exon 19 Mutations and EGFR Compound Mutations 奥希替尼一线治疗不常见EGFR外显子19突变和EGFR复合突变的肺癌 Cheunkarndee, Tia; Guo, Matthew Z.; Houseknecht, Stefanie; Feliciano, Josephine L.; Hann, Christine L.; Lam, Vincent K.; Levy, Benjamin P.; Murray, Joseph C.; Brahmer, Julie R.; Forde, Patrick M.; Marrone, Kristen A.; Scott, Susan C. 分享 收藏
TNIK Inhibition Sensitizes TNIK-Overexpressing Lung Squamous Cell Carcinoma to Radiotherapy Nguyen, Triet; Carrieri, Francesca A.; Connis, Nick; Lafargue, Audrey; Chang, Jinhee; Chan, Aaron; Shetty, Amol C.; Song, Yang; Hoang, Tung; Jagtap, Shreya; Chowdhury, Dipanwita D.; Khan, Muhammad A.; Gabrielson, Kathleen L.; Rezaee, Mohammad; Torres-Ayuso, Pedro; Brognard, John; Hann, Christine L.; Tran, Phuoc T. 分享 收藏
Liquid biopsy-informed precision oncology clinical trial to evaluate the utility of ctDNA comprehensive genomic profiling Fatteh, Maria; Conroy, Michael; Wanchoo, Timsy; Teh, Selina Shiqing; Wehr, Jaime; Balan, Archana; Karchin, Rachel; Verner, Ellen; Karaindrou, Katerina; Xian, Rena; Gocke, Christopher; Lin, Ming-Tseh; Fitzpatrick, Peggy; Hann, Christine L.; Murray, Joseph C.; Lam, Vincent K.; Feliciano, Josephine L.; Brahmer, Julie R.; Marrone, Kristen A.; Forde, Patrick M.; Fiallos, Katie; Petry, Dana; Botsis, Taxiarchis; Sausen, Mark; Canzoniero, Jenna; Tao, Jessica; Anagnostou, Valsamo 分享 收藏
Comprehensive genomic and transcriptomic analyses capture the effects of epigenetic therapy priming on immune checkpoint blockade response in non-small cell lung cancer Landon, Blair V.; Marrone, Kristen A.; Topper, Michael J.; Annapragada, Akshaya; Tsai, Hua-Ling; Balan, Archana; Niknafs, Noushin; Cherry, Christopher; White, James R.; Pereira, Gavin; Adleff, Vilmos; Hu, Chen; Riemer, Joanne; Fitzpatrick, Margaret; Forde, Patrick; Hann, Christine L.; Kelly, Ronan J.; Ettinger, David S.; Levy, Benjamin; Nieva, Jorge; Herman, James; Velculescu, Victor E.; Baylin, Stephen; Brahmer, Julie; Anagnostou, Valsamo 分享 收藏
Clinical and Genomic Characterization of Long-Term Responders Receiving Immune Checkpoint Blockade for Metastatic Non-Small-Cell Lung Cancer 接受免疫检查点阻断治疗转移性非小细胞肺癌的长期应答者的临床和基因组特征 Ghanem, Paola; Murray, Joseph C.; Hsu, Melinda; Guo, Matthew Z.; Ettinger, David S.; Feliciano, Josephine; Forde, Patrick; Hann, Christine L.; Lam, Vincent K.; Levy, Benjamin; Anagnostou, Valsamo; Brahmer, Julie R.; Marrone, Kristen A. 分享 收藏
Clinical features and outcomes of advanced HER2D esophageal/GEJ cancer with brain metastasis Liang, K.; Feliciano, J. L.; Marrone, K. A.; Murray, J. C.; Hann, C. L.; Anagnostou, V.; Tackett, S. A.; Shin, E. J.; Hales, R. K.; Voong, K. R.; Battafarano, R. J.; Yang, S. C.; Broderick, S. R.; Ha, J. S.; Forde, P. M.; Brahmer, J. R.; Lam, V. K. 分享 收藏
Emerging therapies targeting the delta-like ligand 3 (DLL3) in small cell lung cancer Rudin, Charles M. M.; Reck, Martin; Johnson, Melissa L. L.; Blackhall, Fiona; Hann, Christine L. L.; Yang, James Chih-Hsin; Bailis, Julie M. M.; Bebb, Gwyn; Goldrick, Amanda; Umejiego, John; Paz-Ares, Luis 分享 收藏
A machine learning approach to determine the cellular origin of variants in liquid biopsies Canzoniero, Jenna V.; Balan, Archana; Phallen, Jillian; Landon, Blair V.; Sivapalan, Lavanya; Green, Benjamin; Belcaid, Zineb; Scott, Susan C.; Pereira, Gavin; Lam, Vincent K.; Zaidi, Ali H.; Kelly, Ronan J.; Hann, Christine L.; Iams, Wade T.; Lovly, Christine M.; Forde, Patrick M.; Meijer, Gerrit A.; Vink, Geraldine R.; Fijneman, Remond J.; Velculescu, Victor E.; Scharpf, Robert B.; Anagnostou, Valsamo 分享 收藏
Distinct spatial distribution patterns of ALK-inhibitor naive versus ALK-inhibitor treated ALK-positive NSCLC brain metastases Cheunkarndee, Tia; Ganem, Paola; Marrone, Kristen A.; Murray, Joseph C.; Feliciano, Josephine L.; Hann, Christine L.; Scott, Susan C.; Ettinger, David; Anagnostou, Valsamo; Forde, Patrick M.; Brahmer, Julie R.; Levy, Benjamin P.; Lam, Vincent; Kamson, David O. 分享 收藏
Persistent mutation burden drives sustained anti-tumor immune responses in human cancers Niknafs, Noushin; Balan, Archana; Cherry, Christopher; Hummelink, Karlijn; Monkhorst, Kim; Shao, Xiaoshan M.; Belcaid, Zineb; Marrone, Kristen A.; Murray, Joseph; Smith, Kellie N.; Levy, Benjamin; Feliciano, Josephine; Hann, Christine L.; Lam, Vincent; Pardoll, Drew M.; Karchin, Rachel; Seiwert, Tanguy Y.; Brahmer, Julie R.; Forde, Patrick M.; Velculescu, Victor E.; Anagnostou, Valsamo K. 分享 收藏
Dynamics of sequence and structural cell-free DNA landscapes in small-cell lung cancer during systemic therapy Sivapalan, Lavanya; Iams, Wade T.; Belcaid, Zineb; Scott, Susan C.; Niknafs, Noushin; Balan, Archana; White, James R.; Kopparapu, Prasad; Cann, Christopher; Landon, Blair V.; Pereira, Gavin; Velculescu, Victor E.; Hann, Christine L.; Lovly, Christine M.; Anagnostou, Valsamo 分享 收藏
Investigating TNIK as a radiosensitizing target in lung squamous cell carcinoma Nguyen, Triet M.; Lafargue, Audrey M.; Carrieri, Francesca A.; Connis, Nick; Chang, Jinhee; Jagtap, Shreya; Torres-Ayuso, Pedro; Brognard, John; Hann, Christine L.; Tran, Phuoc T. 分享 收藏
Griseofulvin Radiosensitizes Non-Small Cell Lung Cancer Cells and Activates cGAS Wang, Xing; Raman, Natasha; Lemtiri-Chlieh, Ghali; Chang, Jinhee; Jagtap, Shreya; Chowdhury, Dipanwita Dutta; Ballew, Matthew; Carrieri, Francesca Anna; Nguyen, Triet; Nugent, Katriana; Peck, Travis; Levine, Michelle S.; Chan, Aaron; Lam, Christine; Malek, Reem; Hoang, Tung; Phillips, Ryan; Cheng, ZhuoAn; Taparra, Kekoa; Connis, Nick; Hann, Christine L.; Holland, Andrew; Tran, Phuoc T.; Lafargue, Audrey; Wang, Hailun 分享 收藏
Persistent mutation burden drives sustained anti-tumor immune responses Niknafs, Noushin; Balan, Archana; Cherry, Christopher; Hummelink, Karlijn; Monkhorst, Kim; Shao, Xiaoshan M.; Belcaid, Zineb; Marrone, Kristen A.; Murray, Joseph; Smith, Kellie N.; Levy, Benjamin; Feliciano, Josephine; Hann, Christine L.; Lam, Vincent; Pardoll, Drew M.; Karchin, Rachel; Seiwert, Tanguy Y.; Brahmer, Julie R.; Forde, Patrick M.; Velculescu, Victor E.; Anagnostou, Valsamo 分享 收藏
Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice Khan, Sajid; Kellish, Patrick; Connis, Nick; Thummuri, Dinesh; Wiegand, Janet; Zhang, Peiyi; Zhang, Xuan; Budamagunta, Vivekananda; Hua, Nan; Yang, Yang; De, Umasankar; Jin, Lingtao; Zhang, Weizhou; Zheng, Guangrong; Hromas, Robert; Hann, Christine; Zajac-Kaye, Maria; Kaye, Frederic J.; Zhou, Daohong 分享 收藏
Definitive Chemoradiation and Durvalumab Consolidation for Locally Advanced, Unresectable KRAS-mutated Non-Small Cell Lung Cancer Guo, Matthew Z.; Murray, Joseph C.; Ghanem, Paola; Voong, K. Ranh; Hales, Russell K.; Ettinger, David; Lam, Vincent K.; Hann, Christine L.; Forde, Patrick M.; Brahmer, Julie R.; Levy, Benjamin P.; Feliciano, Josephine L.; Marrone, Kristen A. 分享 收藏
Sex-specific differences in immunogenomic features of response to immune checkpoint blockade 免疫检查点阻断反应的免疫基因组学特征的性别特异性差异 Scott, Susan C.; Shao, Xiaoshan M.; Niknafs, Noushin; Balan, Archana; Pereira, Gavin; Marrone, Kristen A.; Lam, Vincent K.; Murray, Joseph C.; Feliciano, Josephine L.; Levy, Benjamin P.; Ettinger, David S.; Hann, Christine L.; Brahmer, Julie R.; Forde, Patrick M.; Karchin, Rachel; Naidoo, Jarushka; Anagnostou, Valsamo 分享 收藏
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