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耿

耿美玉 (Meiyu Geng)

Bohai Rim Advanced Research Institute for Drug Discovery

56H指数
544论文数
1.3W被引数
收录论文 225
发表时间
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Duodenal α-Synuclein PFF Injection Induces Vagus-Related Gut-to-Brain Pathology in C57BL/6J and A53T Transgenic Mice十二指肠α-突触核蛋白PFF注射诱导C57BL/6J和A53T转基因小鼠发生迷走神经相关的肠道-大脑病理变化
errBrain Sciences
IF2.8
err2026-08-01
err0
errOAAI
errMengfei Wang; Guangqiang Sun; Peifeng Wan; Zitong Wang; Yali Nie; Hongchun Liu; Meiyu Geng; Ming Liu; Yu Zhang
err分享
err收藏
Sodium oligomannate reduces cerebral infarction and improves neurological function through microbiota remodeling in MCAO/R rats奥利加曼纳通过重塑肠道菌群减少MCAO/R大鼠的脑梗死并改善神经功能
errFrontiers in Pharmacology
IF4.8
err2026-07-20
err0
errOAAI
errJH Jin Han; WZ Wei Zhao; RD Rui Deng; YW Yu Wang; WG Wenping Gong; ZW Zitong Wang; GS Guangqiang Sun; HL Hongchun Liu; MG Meiyu Geng; YZ Yu Zhang
err分享
err收藏
GV-971 Ameliorates Chronic Restraint Stress-Induced Depression-like Phenotypes Accompanied by Reshaping of the Microbiota–Gut–Brain AxisGV-971改善慢性束缚应激诱导的抑郁样行为，并伴有重塑微生物-肠-脑轴
errMarine Drugs
IF5.4
err2026-05-24
err0
errOAAI
errZhuandi He; Yali Nie; Changcai Li; Guangqiang Sun; Wei Zheng; Hongchun Liu; Meiyu Geng; Jingwei Tian; Yu Zhang
err分享
err收藏
Microglial Nrf2 Activation Orchestrates Ferroptosis Inhibition and α-Synuclein Clearance in Parkinson’s Disease小胶质细胞Nrf2激活调控铁死亡抑制和α-突触核蛋白清除在帕金森病中的作用
errInternational Journal of Molecular Sciences
IF4.9
err2026-05-20
err0
errOAAI
errFeifan Chen; Yingneng Liang; Wen Li; Yaxin Guo; Hongchun Liu; Meiyu Geng; Ming Liu; Yu Zhang
err分享
err收藏
Transformable nanoassembly of CXCL16 peptide-SN38 conjugate improves intratumor permeation and retention in peritoneal metastasesCXCL16肽-SN38偶联物的可转换纳米组装体改善了腹膜转移瘤内的渗透和滞留
errJournal of Controlled Release
IF11.5
err2026-04-30
err0
PREAI
errYi Lu; Yifei Chi; Siyuwei Cao; Weimin Nie; Yichen Zhang; Shuai Wang; Mingxuan Huang; Yiyu Liang; Yao Wu; Jingbo Wu; Renjie Wang; Min Huang; Wenfu Tan; Meiyu Geng; Zhiwen Zhang
err分享
err收藏
Sphingosine-1-Phosphate Receptor 3 Confers Tumor Metastasis in Lung Cancer Resistant to Third-Generation EGFR Inhibitor鞘氨醇-1-磷酸受体3促进对第三代EGFR抑制剂耐药的肺癌转移
errMedComm
IF10.7
err2026-04-23
err0
errOAAI
errMengzhen Lai; Jiaying Chen; Ye Qin; Hui Zhang; Zilu Pan; Tao Zhang; Linjiang Tong; Haotian Tang; Gang Bai; Qiupei Liu; Yan Li; Fang Feng; Peiran Song; Yingqiang Liu; Yi Chen; Yan Fang; Bencan Tang; Meiyu Geng; Ker Yu; Hao Chen; Jian Ding; Hua Xie
err分享
err收藏
Discovery of Novel MLKL PROTAC Degraders for the Treatment of Hepatocellular Carcinoma via Promoting Parthanatos通过促进帕斯他托斯发现新型MLKL PROTAC降解剂，用于治疗肝细胞癌
errJournal of Medicinal Chemistry
IF6.8
err2026-03-16
err0
PREAI
errChao Chen; Kaiyuan Liu; Xinlei Wang; Ruyu Yan; Yang Dai; Yiming Li; Chaoyue Xia; Yue Zhang; Biyu Yang; Xiangli Chen; Wei Zheng; Meiyu Geng; Yaxi Yang; Xifei Jiang; Jing Ai; Bing Zhou
err分享
err收藏
Discovery of isoindoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents作为抗炎剂的异吲哚啉-2(1H)-甲酰胺STING抑制剂的发现
errMolecular Diversity
IF3.8
err2025-12-11
err0
PREAI
errXiaoqian Zhou; Shumin Zang; Shanyan Yao; Hongfei Zhou; Xiyuan Wang; Meiyu Geng; Zhengsheng Zhan; Zuoquan Xie; Wenhu Duan
err分享
err收藏
Discovery of a potent and orally bioavailable 3,3-dimethyl-2-oxoindoline STING inhibitor发现一种强效且口服生物利用度高的3,3-二甲基-2-氧代吲哚啉STING抑制剂
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-10-09
err0
PREAI
errWenxin Li; Xiyuan Wang; Shumin Zang; Rongyao Zhou; Hongfei Zhou; Hangtian Yue; Meiyu Geng; Zhengsheng Zhan; Zuoquan Xie; Wenhu Duan
err分享
err收藏
Discovery of 3,4-dihydroisoquinoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents作为抗炎药物的3,4-二氢异喹啉-2(1H)-甲酰胺STING抑制剂的发现
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-07-01
err0
PREAI
errXiaoqian Zhou; Hangtian Yue; Xiyuan Wang; Shumin Zang; Han Li; Shanyan Yao; Meiyu Geng; Zhengsheng Zhan; Zuoquan Xie; Wenhu Duan
err分享
err收藏
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1人参皂苷(20)S-APPT通过靶向FSP1诱导肝细胞癌和胆管癌发生铁死亡。
errActa Pharmacologica Sinica
IF8.4
err2025-06-23
err0
PREAI
errFan-yu Liu; Yuan-jie Yang; Xue-long Wang; Yan Hong; Xiao-peng Ou-Yang; Lu Chang; Nan-lin Zhu; Ao Huang; Min-min Zhang; Jia Liu; Mei-yu Geng; Ai-jun Shen
err分享
err收藏
Design, synthesis, and biological evaluation of KDM5B degraders against hematologic malignancy cellsKDM5B降解剂的设计、合成及其对血液恶性肿瘤细胞的生物活性评价
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-06-19
err0
PREAI
errXiaowen Liu; Jiarong Li; Yihao Guo; Zhicheng Xie; Meiyu Geng; Youhong Hu; Aijun Shen; Zhuo Zhang
err分享
err收藏
Discovery of indole derivatives as STING degraders作为STING降解剂的吲哚衍生物的发现
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-05-28
err0
PREAI
errAn, Yuxiang; Zhang, Yan; Luo, Xin; Lan, Yaohan; Geng, Meiyu; Duan, Wenhu; Xie, Zuoquan; Zhang, Hefeng
err分享
err收藏
Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth发现假榆酸B的肼基酰胺衍生物用于重编程肿瘤相关巨噬细胞以对抗肿瘤生长
errMOLECULES
IF4.6
err2025-05-08
err0
errOAAI
errPeng, Xia; Yu, Siqi; Xu, Lin; Wang, Qinghua; Yang, Lin; Su, Yi; Xiong, Zhirou; Shao, Mengjie; Geng, Meiyu; Zhang, Ao; Zhang, Lei; Ai, Jing; Ding, Chunyong
err分享
err收藏
Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents具有二氟苯并二氧戊环结构基序的强效STING抑制剂的发现及其作为强效抗炎剂的应用
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-06
err0
PREAI
errShen, Ancheng; Wang, Xiyuan; Chen, Qingxuan; Zhang, Yan; Wang, Fang; Li, Yuqiang; Liu, Zhiguo; Deng, Liufu; Ouyang, Wanli; Geng, Meiyu; Song, Zilan; Xie, Zuoquan
err分享
err收藏
Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy基于优化后的超SILAC策略的全局组蛋白翻译后修饰定量揭示甘草素抗炎的表观遗传机制
errFRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
IF4.3
err2025-03-27
err0
errOAAI
errLiu, Ping; Zhang, Jun; Zhang, Jingdan; Yuan, Yucheng; Liu, Zhiqing; Chen, Sixian; Chen, Kaifeng; Dong, Li; Cheng, Zhiyuan; Zhang, Yinan; Geng, Meiyu; Zhao, Wensi; Xie, Dong
err分享
err收藏
Phosphinothio(seleno)ation of alkynes/olefins and application on the late-stage functionalization of natural products
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-12-05
err0
errOAAI
errShao, Chang-Wei; Wan, Pei-Feng; Xu, Quan; Yang, Ze-Nan; Geng, Mei-Yu; Zhang, Yu; Zhang, Xing-Hua; Li, Xu-Wen
err分享
err收藏
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-12-01
err2
PREAI
errTang, Mingze; Zhou, Xuan; Shen, Qianqian; Fang, Chen; Peng, Xia; Ji, Yinchun; Zhu, Guijun; Geng, Meiyu; Chen, Yi; Duan, Wenhu; Ai, Jing; Zhang, Hefeng
err分享
err收藏
Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
errCELL DISCOVERY
IF12.5
err2024-11-19
err0
errOAAI
errWang, Xinyi; Xie, Zuoquan; Yuan, Jie; Jin, Enjing; Lian, Wen; Chang, Shuaishuai; Sun, Guangqiang; Feng, Zhengnan; Xu, Hui; Du, Chen; Yang, Xinying; Xia, Aihua; Qiu, Ji; Zhang, Qingli; Lin, Feifei; Liu, Jia; Li, Liang; Du, Xiaoguang; Xiao, Zhongping; Yi, Zhou; Luo, Zhiyu; Ge, Changrong; Li, Rui; Zheng, Mingyue; Jiang, Yi; Wang, Tao; Zhang, Jing; Guo, Qihao; Geng, Meiyu
err分享
err收藏
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2024-11-01
err0
errOAAI
errXie, Zuoquan; Zhou, Qinming; Hu, Jin; He, Lu; Meng, Huangyu; Liu, Xiaoni; Sun, Guangqiang; Luo, Zhiyu; Feng, Yuan; Li, Liang; Chu, Xingkun; Du, Chen; Yang, Dabing; Yang, Xinying; Zhang, Jing; Ge, Changrong; Zhang, Xiang; Chen, Sheng; Geng, Meiyu
err分享
err收藏

研究方向

靶向Aβ抗阿尔茨海默病药物研发激酶c-MetALKFGFR抑制剂及其生物标志物Hsp90抑制剂及其生物标志物肿瘤代谢及其治疗策略肿瘤微环境及其治疗策略
合作学者
合作期刊
J
Jeffrey L. Cummings
H 指数: 176 · 论文数: 1.5K
刘泓 封面图
刘泓 (Hong Liu)
H 指数: 135 · 论文数: 2.8K
樊
樊嘉 (Jia Fan)
H 指数: 126 · 论文数: 1.5K
S
Sarah Spiegel
H 指数: 124 · 论文数: 597
杨
杨敏 (Min Yang)
H 指数: 121 · 论文数: 3.6K
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