未登录 The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma Chang, Cunjie; Rajasekaran, Muthukumar; Qiao, Yiting; Dong, Heng; Wang, Yu; Xia, Hongping; Deivasigamani, Amudha; Wu, Minjie; Sekar, Karthik; Gao, Hengjun; Sun, Mengqing; Niu, Yuqin; Li, Qian; Tao, Lin; Yan, Zhen; Wang, Menglan; Chen, Shasha; Zhao, Shujuan; Chen, Dajing; Li, Lina; Yang, Fan; Gao, Haojin; Chen, Baodong; Su, Ling; Xu, Liang; Chen, Ye; Seshachalam, Veerabrahma Pratap; Chen, Gongxing; Gunaratne, Jayantha; Hong, Wanjin; Shi, Junping; Chen, Gongying; Grierson, David S.; Chabot, Benoit; Xie, Tian; Hui, Kam Man; Chen, Jianxiang 分享 收藏
The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation Dahal, Subha; Cheng, Ran; Cheung, Peter K.; Been, Terek; Malty, Ramy; Geng, Melissa; Manianis, Sarah; Shkreta, Lulzim; Jahanshahi, Shahrazad; Toutant, Johanne; Chan, Rose; Park, Sean; Brockman, Mark A.; Babu, Mohan; Mubareka, Samira; Mossman, Karen; Banerjee, Arinjay; Gray-Owen, Scott; Brown, Martha; Houry, Walid A.; Chabot, Benoit; Grierson, David; Cochrane, Alan 分享 收藏
分享 收藏
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells Sohail, Muhammad; Shkreta, Lulzim; Toutant, Johanne; Rabea, Safwat; Babeu, Jean-Philippe; Huard, Caroline; Coulombe-Huntington, Jasmin; Delannoy, Aurelie; Placet, Morgane; Geha, Sameh; Gendron, Fernand-Pierre; Boudreau, Francois; Tyers, Mike; Grierson, David S.; Chabot, Benoit 分享 收藏
分享 收藏
Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production Chabrolles, Helene; Auclair, Heloise; Vegna, Serena; Lahlali, Thomas; Pons, Caroline; Michelet, Maud; Coute, Yohann; Belmudes, Lucid; Chadeuf, Gilliane; Kim, Yujin; Di Bernardo, Ariel; Jalaguier, Pascal; Cosset, Francois-Loic; Fusil, Floriane; Rivoire, Michel; Arnold, Lee D.; Lopatin, Uri; Combet, Christophe; Zoulim, Fabien; Grierson, David; Chabot, Benoit; Lucifora, Julie; Durantel, David; Salvetti, Anna 分享 收藏
分享 收藏
Development of Novel Monoamine Oxidase-B (MAO-B) Inhibitors with Reduced Blood-Brain Barrier Permeability for the Potential Management of Noncentral Nervous System (CNS) Diseases Gealageas, Ronan; Devineau, Alice; So, Pauline P. L.; Kim, Catrina M. J.; Surendradoss, Jayakumar; Buchwalder, Christian; Heller, Markus; Goebeler, Verena; Dullaghan, Edith M.; Grierson, David S.; Putnins, Edward E. 分享 收藏
Identification of hepatitis B virus core protein nuclear interacting factors points to RNA binding proteins as major regulators of HBV replication Chabrolles, H.; Vegna, S.; Heloise, A.; Coute, Y.; Belmudes, L.; Kim, Y.; Arnold, L.; Grierson, D.; Chabot, B.; Combet, C.; Zoulim, F.; Lucifora, J.; Durantel, D.; Salvetti, A. 分享 收藏
Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication Shkreta, Lulzim; Blanchette, Marco; Toutant, Johanne; Wilhelm, Emmanuelle; Bell, Brendan; Story, Benjamin A.; Balachandran, Ahalya; Cochrane, Alan; Cheung, Peter K.; Harrigan, P. Richard; Grierson, David S.; Chabot, Benoit 分享 收藏
A Parallel Synthesis Approach to the Identification of Novel Diheteroarylamide-Based Compounds Blocking HIV Replication: Potential Inhibitors of HIV-1 Pre-mRNA Alternative Splicing Cheung, Peter K.; Horhant, David; Bandy, Laura E.; Zamiri, Maryam; Rabea, Safwat M.; Karagiosov, Stoyan K.; Matloobi, Mitra; McArthur, Steven; Harrigan, P. Richard; Chabot, Benoit; Grierson, David S. 分享 收藏
Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth Prudent, Renaud; Vassal-Stermann, Emilie; Chi-Hung Nguyen; Pillet, Catherine; Martinez, Anne; Prunier, Chloe; Barette, Caroline; Soleilhac, Emmanuelle; Filhol, Odile; Beghin, Anne; Valdameri, Glaucio; Honore, Stephane; Aci-Seche, Samia; Grierson, David; Antonipillai, Juliana; Li, Rong; Di Pietro, Attilio; Dumontet, Charles; Braguer, Diane; Florent, Jean-Claude; Knapp, Stefan; Bernard, Ora; Lafanechere, Laurence 分享 收藏
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights Lopez-Ramos, Miriam; Prudent, Renaud; Moucadel, Virginie; Sautel, Celine F.; Barette, Caroline; Lafanechere, Laurence; Mouawad, Liliane; Grierson, David; Schmidt, Frederic; Florent, Jean-Claude; Filippakopoulos, Panagis; Bullock, Alex N.; Knapp, Stefan; Reiser, Jean-Baptiste; Cochet, Claude 分享 收藏
Synthesis and Biological Evaluation of C-5 Methyl Substituted 4-Arylthio and 4-Aryloxy-3-Iodopyridin-2(1H)-one Type Anti-HIV Agents Guillemont, Jerome; Benjahad, Abdellah; Oumouch, Said; Decrane, Laurence; Palandjian, Patrice; Vernier, Daniel; Queguiner, Laurence; Andries, Koen; de Bethune, Marie-Pierre; Hertogs, Kurt; Grierson, David S.; Nguyen, Chi Hung 分享 收藏
分享 收藏
分享 收藏
分享 收藏
In vitro phototoxicity of glycoconjugated porphyrins and chlorins in colorectal adenocarcinoma (HT29) and retinoblastoma (Y79) cell lines Maillard, Ph.; Loock, B.; Grierson, D. S.; Laville, I.; Blais, J.; Doz, F.; Desjardins, L.; Carrez, D.; Guerquin-Kern, J. -L.; Croisy, A. 分享 收藏
Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance Bakkour, Nadia; Lin, Yea-Lih; Maire, Sophie; Ayadi, Lilia; Mahuteau-Betzer, Florence; Nguyen, Chi Hung; Mettling, Clement; Portales, Pierre; Grierson, David; Chabot, Benoit; Jeanteur, Philippe; Branlant, Christiane; Corbeau, Pierre; Tazi, Jamal 分享 收藏
分享 收藏