未登录 Non-genetic remodeling drives leukemia propagation and reveals actionable vulnerabilities in acute myeloid leukemia 非遗传性重塑驱动白血病传播并揭示急性髓系白血病中的可操作易损性 Larrue, Clement; Angelino, Paolo; Mouche, Sarah; Green, Alexa S.; Boet, Emeline; Boussaid, Ismael; Perez-Carretero, Claudia; Birsen, Rudy; Sajot, Maxime; Mckee, Thomas A.; Sahal, Ambrine; Chapuis, Nicolas; Vergez, Francois; Recher, Christian; Mansat-De Mas, Veronique; Kosmider, Olivier; Sujobert, Pierre; Catez, Frederic; Diaz, Jean-Jacques; Sarry, Jean-Emmanuel; Tsantoulis, Petros; Tamburini, Jerome 分享 收藏
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Specific modulation of 28S_Um2402 rRNA 2′-O-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial-mesenchymal transition in different mammary cell contexts 28S_Um2402 rRNA 2 ′-O-核糖甲基化的特异性调节作为不同乳腺细胞环境中ZEB1-induced上皮-间充质转化的新型表观遗传标记 Morin, Chloe; Paraqindes, Hermes; Van Long, Flora Nguyen; Isaac, Caroline; Thomas, Emilie; Pedri, Dennis; Pulido-Vicuna, Carlos Ariel; Morel, Anne-Pierre; Marchand, Virginie; Motorin, Yuri; Carrere, Marjorie; Auclair, Jessie; Attignon, Valery; Pommier, Roxane M.; Ruiz, Emmanuelle; Bourdelais, Fleur; Catez, Frederic; Durand, Sebastien; Ferrari, Anthony; Viari, Alain; Marine, Jean-Christophe; Puisieux, Alain; Diaz, Jean-Jacques; Moyret-Lalle, Caroline; Marcel, Virginie 分享 收藏
Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis 由白介素-6处理的造血干细胞和祖细胞生成的单核细胞分泌钙卫蛋白,该物质抑制红细胞生成。 Marchand, Valentine; Laplane, Lucie; Valensi, Louis; Plo, Isabelle; Aglave, Marine; Silvin, Aymeric; Pasquier, Florence; Porteu, Francoise; Vainchenker, William; Selimoglu-Buet, Dorothee; Droin, Nathalie; Raslova, Hana; Marcel, Virginie; Diaz, Jean-Jacques; Fontenay, Michaela; Solary, Eric 分享 收藏
Intricate ribosome composition and translational reprogramming in epithelial-mesenchymal transition 上皮-间质转化中复杂的核糖体组成和翻译重编程 Morin, Chloe; Baudin-Baillieu, Agnes; Van Long, Flora Nguyen; Isaac, Caroline; Bidou, Laure; Arbes, Hugo; Francois, Pauline; Pommier, Roxane M.; Adrait, Annie; Saku, Akari; Gran, Stephanie; Machkouri, Camelia; Vanbelle, Christophe; Morichon, Romain; Boissan, Mathieu; Catez, Frederic; Ferrari, Anthony; Morel, Anne-Pierre; Coute, Yohann; Chat, Sophie; Giudice, Emmanuel; Gillet, Reynald; Puisieux, Alain; Moyret-balle, Caroline; Diaz, Jean- Jacques; Namy, Olivier; Marcel, Virginie 分享 收藏
Selective translational activation of PBK (PDZ- binding kinase) reveals a molecular vulnerability of drug-tolerant persister cells to targeted therapies in EGFR-mutant lung adenocarcinoma Leonce, Camille; Desage, Anne-Laure; Mourksi, Nour El-Houda; De Souza, Genevieve; Vanbervliet, Beatrice; Charrondiere, Camille; Nicq, Constance; Neri, Jeremy; Swalduz, Aurelie; Tonon, Laurie; Cumunel, Eric; Gadot, Nicolas; Ichim, Gabriel; Diaz, Jean-Jacques; Lovly, Christine; Mazieres, Julien; Tabutin, Mayeul; Perol, Maurice; Lantuejoul, Sylvie; Calvayrac, Olivier; Forest, Fabien; Marcel, Virginie; Saintigny, Pierre; Ortiz-Cuaran, Sandra 分享 收藏
Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment Berthenet, Kevin; Aimontche, Eliezer; El Mrini, Sara; Briere, Johan; Pion, Nathalie; Iacono, Isabelle; Brejon, Stephanie; Monier, Karine; Catez, Frederic; Ichim, Gabriel; Combaret, Valerie; Mertani, Hichem C.; Diaz, Jean-Jacques; Albaret, Marie Alexandra 分享 收藏
Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration Schaeffer, Julia; Vilallongue, Noemie; Decourt, Charlotte; Blot, Beatrice; El Bakdouri, Nacera; Plissonnier, Elise; Excoffier, Blandine; Paccard, Antoine; Diaz, Jean-Jacques; Humbert, Sandrine; Catez, Frederic; Saudou, Frederic; Nawabi, Homaira; Belin, Stephane 分享 收藏
The stress sensor GCN2 differentially controls ribosome biogenesis in colon cancer according to the nutritional context Piecyk, Marie; Triki, Mouna; Laval, Pierre-Alexandre; Duret, Cedric; Fauvre, Joelle; Cussonneau, Laura; Machon, Christelle; Guitton, Jerome; Rama, Nicolas; Gibert, Benjamin; Ichim, Gabriel; Catez, Frederic; Bourdelais, Fleur; Durand, Sebastien; Diaz, Jean-Jacques; Coste, Isabelle; Renno, Toufic; Manie, Serge N.; Aznar, Nicolas; Ansieau, Stephane; Ferraro-Peyret, Carole; Chaveroux, Cedric 分享 收藏
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HSV-1 cellular model reveals links between aggresome formation and early step of Alzheimer's disease Albaret, Marie Alexandra; Textoris, Julien; Dalzon, Bastien; Lambert, Jeremy; Linard, Morgane; Helmer, Catherine; Hacot, Sabine; Ghayad, Sandra E.; Ferreol, Martial; Mertani, Hichem C.; Diaz, Jean-Jacques 分享 收藏
Ribosome biogenesis-based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group 在子宫内膜癌的内分泌治疗中基于核糖体生物发生的预测性生物标志物 (阿那曲唑) 联合mTOR抑制剂 (Vistusertib): VICTORIA试验与GINECO集团合作的转化研究 Mourksi, Nour-El-Houda; Dalban, Cecile; Colombe-Vermorel, Amelie; Odeyer, Laetitia; Simioni, Valentin; Frenel, Jean-Sebastien; Fabbro, Michel; Bazan, Fernando; Abadie-Lacourtoisie, Sophie; Coquan, Elodie; Martinez, Severine; Garin, Gwenaelle; Tabone-Eglinger, Severine; Treilleux, Isabelle; Chabaud, Sylvie; Perol, David; Ray-Coquard, Isabelle; Heudel, Pierre-Etienne; Diaz, Jean-Jacques; Marcel, Virginie 分享 收藏