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Role of SCAP in regulation of pancreatic homeostasis, pancreatitis, and tumorigenesis SCAP在调节胰腺稳态、胰腺炎和肿瘤发生中的作用 Lilly, Anna C.; Pavlov, Valerii A.; Pirestani, Shabnam; Chatoff, Adam; Cai, Kathy Q.; Cukierman, Edna; Snyder, Nathaniel W.; Astsaturov, Igor; Golemis, Erica A. 分享 收藏
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RTx-303, an Orally Bioavailable Polθ Polymerase Inhibitor That Potentiates PARP Inhibitors in BRCA Mutant Tumors Chandramouly, Gurushankar; Fried, William; Gordon, John; Ralph, Douglas; Keuk, Channita; Kumari, Sangeeta; Ramanjulu, Mercy; Auerbacher, William; Minakhin, Leonid; Tredinnick, Taylor; Tiberi, Bernadette; Morton, George; Betsch, Robert; Cai, Kathy Q.; Vekariya, Umeshkumar M.; Tyagi, Mrityunjay; Skorski, Tomasz; Karakashev, Sergey; Johnson, Neil; Childers Jr, Wayne E.; Chen, Xiaojiang S.; Pomerantz, Richard T. 分享 收藏
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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma Hueser, Laura; Chhabra, Yash; Gololobova, Olesia; Wang, Vania; Liu, Guanshu; Dixit, Agrani; Rocha, Murilo Ramos; Harper, Elizabeth I.; Fane, Mitchell E.; Marino-Bravante, Gloria E.; Zabransky, Daniel J.; Cai, Kathy Q.; Utikal, Jochen; Slusher, Barbara S.; Walston, Jeremy; Lipson, Evan J.; Witwer, Kenneth W.; Weeraratna, Ashani T. 分享 收藏
BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance Nesic, Ksenija; Krais, John J.; Wang, Yifan; Vandenberg, Cassandra J.; Patel, Pooja; Cai, Kathy Q.; Kwan, Tanya; Lieschke, Elizabeth; Ho, Gwo-Yaw; Barker, Holly E.; Bedo, Justin; Casadei, Silvia; Farrell, Andrew; Radke, Marc; Shield-Artin, Kristy; Penington, Jocelyn S.; Geissler, Franziska; Kyran, Elizabeth; Betsch, Robert; Xu, Lijun; Zhang, Fan; Dobrovic, Alexander; Olesen, Inger; Kristeleit, Rebecca; Oza, Amit; McNeish, Iain; Ratnayake, Gayanie; Traficante, Nadia; DeFazio, Anna; Bowtell, David D. L.; Harding, Thomas C.; Lin, Kevin; Swisher, Elizabeth M.; Kondrashova, Olga; Scott, Clare L.; Johnson, Neil; Wakefield, Matthew J. 分享 收藏
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Targeting DHX9 triggers interferon response and replication stress in small cell lung cancer Murayama, Takahiko; Nakayama, Jun; Cai, Kathy Q.; Miyata, Kenichi; Efimov, Andrey; Tan, Yinfei; Zhou, Yan; Campbell, Kerry S.; Yang, Yibin; Balachandran, Siddharth; Canadas, Israel 分享 收藏
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Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints Cannon, Alexa C.; Budagyan, Konstantin; Uribe-Alvarez, Cristina; Kurimchak, Alison M.; Araiza-Olivera, Daniela; Cai, Kathy Q.; Peri, Suraj; Zhou, Yan; Duncan, James S.; Chernoff, Jonathan 分享 收藏
Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer 靶向DHX9触发小细胞肺癌的肿瘤内在干扰素反应和复制应激 Murayama, Takahiko; Nakayama, Jun; Jiang, Xinpei; Miyata, Kenichi; Morris, Alexander D.; Cai, Kathy Q.; Prasad, Rahul M.; Ma, Xueying; Efimov, Andrey; Belani, Neel; Gerstein, Emily R.; Tan, Yinfei; Zhou, Yan; Kim, William; Maruyama, Reo; Campbell, Kerry S.; Chen, Lu; Yang, Yibin; Balachandran, Siddharth; Canadas, Israel 分享 收藏
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential Klochkova, Alena; Karami, Adam L.; Fuller, Annie D.; Parham, Louis R.; Panchani, Surali R.; Natarajan, Shruthi; Jackson, Jazmyne L.; Mu, Anbin; Tan, Yinfei; Cai, Kathy Q.; Klein-Szanto, Andres J.; Muir, Amanda B.; Tetreault, Marie-Pier; Grana, Xavier; Hamilton, Kathryn E.; Whelan, Kelly A. 分享 收藏
Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies Restifo, Diana; McDermott, Joseph R.; Cvetkovic, Dusica; Dos Santos, Troy; Ogier, Charline; Surumbayeva, Aizhan; Handorf, Elizabeth A.; Schimke, Caleb; Ma, Charlie; Cai, Kathy Q.; Olszanski, Anthony J.; Kathad, Umesh; Bhatia, Kishor; Sharma, Panna; Kulkarni, Aditya; Astsaturov, Igor 分享 收藏
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TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype TET1和TDG抑制肠道肿瘤发生中的炎症反应: 对具有CpG岛甲基化表型的结直肠肿瘤的影响 Tricarico, Rossella; Madzo, Jozef; Scher, Gabrielle; Cohen, Maya; Jelinek, Jaroslav; Maegawa, Shinji; Nagarathinam, Rajeswari; Scher, Carly; Chang, Wen-Chi; Nicolas, Emmanuelle; Slifker, Michael; Zhou, Yan; Devarajan, Karthik; Cai, Kathy Q.; Kwok, Tim; Nakajima, Pamela; Xu, Jinfei; Mancuso, Pietro; Doneddu, Valentina; Bagella, Luigi; Williams, Riley; Balachandran, Siddharth; Maskalenko, Nicholas; Campbell, Kerry; Ma, Xueying; Canadas, Israel; Viana-Errasti, Julen; Moreno, Victor; Valle, Laura; Grivennikov, Sergei; Peshkova, Iuliia; Kurilenko, Natalia; Mazitova, Aleksandra; Koltsova, Ekaterina; Lee, Hayan; Walsh, Martin; Duttweiler, Reuben; Whetstine, Johnathan R.; Yen, Timothy J.; Issa, Jean-Pierre; Bellacosa, Alfonso 分享 收藏
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