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The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT) Pharaoh, Gavin; Kamat, Varun; Kannan, Sricharan; Stuppard, Rudolph S.; Whitson, Jeremy; Martin-Perez, Miguel; Qian, Wei-Jun; MacCoss, Michael J.; Villen, Judit; Rabinovitch, Peter; Campbell, Matthew D.; Sweet, Ian R.; Marcinek, David J. 分享 收藏
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The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging Sanchez-Contreras, Monica; Sweetwyne, Mariya T.; Tsantilas, Kristine A.; Whitson, Jeremy A.; Campbell, Matthew D.; Kohrn, Brenden F.; Kim, Hyeon Jeong; Hipp, Michael J.; Fredrickson, Jeanne; Nguyen, Megan M.; Hurley, James B.; Marcinek, David J.; Rabinovitch, Peter S.; Kennedy, Scott R. 分享 收藏
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health NIH SenNet联盟绘制人类整个生命周期中的衰老细胞以了解生理健康 Lee, Patty J.; Benz, Christopher C.; Blood, Philip; Boerner, Katy; Campisi, Judith; Chen, Feng; Daldrup-Link, Heike; De Jager, Phil; Ding, Li; Duncan, Francesca E.; Eickelberg, Oliver; Fan, Rong; Finkel, Toren; Furman, David; Garovic, Vesna; Gehlenborg, Nils; Glass, Carolyn; Heckenbach, Indra; Joseph, Ziv-Bar; Katiyar, Pragati; Kim, So-Jin; Koenigshoff, Melanie; Kuchel, George A.; Lee, Haesung; Lee, Jun Hee; Ma, Jian; Ma, Qin; Melov, Simon; Metis, Kay; Mora, Ana L.; Musi, Nicolas; Neretti, Nicola; Passos, Joao F.; Rahman, Irfan; Rivera-Mulia, Juan Carlos; Robson, Paul; Rojas, Mauricio; Roy, Ananda L.; Scheibye-Knudsen, Morten; Schilling, Birgit; Shi, Pixu; Silverstein, Jonathan C.; Suryadevara, Vidyani; Xie, Jichun; Wang, Jinhua; Wong, A. Ian; Niedernhofer, Laura J.; Wang, Siyuan (Steven); Anvari, Hannah; Balough, Julia; Benz, Christopher; Bons, Joanna; Brenerman, Boris; Evans, William; Gerencser, Akos; Gregory, Heather; Hansen, Malene; Justice, Jamie; Kapahi, Pankaj; Murad, Natalia; O'Broin, Amy; Pavone, Mary Ellen; Powell, Mark; Scott, Gary; Shanes, Elisheva; Shankaran, Mahalakshmi; Verdin, Eric; Winer, Daniel; Wu, Fei; Adams, Andrew; Blood, Philip D.; Bueckle, Andreas; Cao-Berg, Ivan; Chen, Hao; Davis, Michael; Filus, Shane; Hao, Yuhan; Hartman, Austin; Hasanaj, Euxhen; Helfer, Jesse; Herr, Bruce, II; Bar Joseph, Ziv; Molla, Gesmira; Mou, Gloria; Puerto, Juan; Quardokus, Ellen M.; Ropelewski, Alexander J.; Ruffalo, Matt; Satija, Rahul; Schwenk, Melissa; Scibek, Robin; Shirey, William; Sibilla, Max; Welling, Joel; Yuan, Zhou; Bonneau, Richard; Christiano, Angela; Izar, Benjamin; Menon, Vilas; Owens, David M.; Phatnani, Hemali; Smith, Colin; Suh, Yousin; Teich, Andrew F.; Bekker, Valerie; Chan, Cliburn; Coutavas, Elias; Hartwig, Matthew G.; Ji, Zhicheng; Nixon, Andrew B.; Dou, Zhixun; Rajagopal, Jayaraj; Slavov, Nikolai; Holmes, David, III; Jurk, Diana; Kirkland, James L.; Lagnado, Anthony; Tchkonia, Tamara; Abraham, Kristin; Dibattista, Amanda; Fridell, Yih-Woei; Howcroft, T. Kevin; Jhappan, Chamelli; Montes, Viviana Perez; Prabhudas, Mercy; Resat, Haluk; Taylor, Veronica; Kumar, Manoj; Cigarroa, Francisco; Cohn, Rachel; Cortes, Tiffany M.; Courtois, Elise; Chuang, Jeffrey; Dave, Monica; Domanskyi, Sergii; Enninga, Elizabeth Ann Lieser; Eryilmaz, Giray Naim; Espinoza, Sara E.; Gelfond, Jon; Kirkland, James; Kuo, Chia-Ling; Lehman, Julia S.; Aguayo-Mazzucato, Cristina; Meves, Alexander; Rani, Meenakshi; Sanders, Shane; Thibodeau, Asa; Tullius, Stefan G.; Ucar, Duygu; White, Brian; Wu, Qian; Xu, Ming; Yamaguchi, Seiji; Assarzadegan, Naziheh; Cho, Chun-Seok; Hwang, Irene; Hwang, Yongha; Xi, Jingyue; Adeyi, Oyedele A.; Aliferis, Constantin F.; Bartolomucci, Alessandro; Dong, Xiao; DuFresne-To, Mickayla J.; Ikramuddin, Sayeed; Johnson, Steve G.; Nelson, Andrew C.; Revelo, Xavier S.; Trevilla-Garcia, Claudia; Sedivy, John M.; Thompson, Elizabeth L.; Robbins, Paul D.; Wang, Jinhua; Aird, Katherine M.; Alder, Jonathan K.; Beaulieu, Delphine; Bueno, Marta; Calyeca, Jazmin; Chamucero-Millaris, Julian A.; Chan, Stephen Y.; Chung, Dongjun; Corbett, Anthony; Gorbunova, Vera; Gowdy, Kymberly M.; Gurkar, Aditi; Horowitz, Jeffrey C.; Hu, Qianjiang; Kaur, Gagandeep; Khaliullin, Timur O.; Lafyatis, Robert; Lanna, Serafina; Li, Dongmei; Ma, Anjun; Morris, Alison; Muthumalage, Thivanka M.; Peters, Victor; Pryhuber, Gloria S.; Reader, Brenda F.; Rosas, Lorena; Sembrat, John C.; Shaikh, Sadiya; Shi, Hangchuan; Stacey, Sean D.; St Croix, Claudette; Wang, Cankun; Wang, Qixin; Watts, Andrew; Gu, Liangcai; Lin, Yiing; Rabinovitch, Peter S.; Sweetwyne, Mariya T.; Artyomov, Maxim N.; Ballentine, Samuel J.; Chheda, Milan G.; Davies, Sherri R.; DiPersio, John F.; Fields, Ryan C.; Fitzpatrick, James A. J.; Fulton, Robert S.; Imai, Shin-ichiro; Jain, Sanjay; Ju, Tao; Kushnir, Vladimir M.; Link, Daniel C.; Ben Major, Michael; Oh, Stephen T.; Rapp, Daniel; Rettig, Michael P.; Stewart, Shelia A.; Veis, Deborah J.; Vij, Kiran R.; Wendl, Michael C.; Wyczalkowski, Matthew A.; Craft, Joseph E.; Enninful, Archibald; Farzad, Negin; Gershkovich, Peter; Halene, Stephanie; Kluger, Yuval; VanOudenhove, Jennifer; Xu, Mina; Yang, Junchen; Yang, Mingyu 分享 收藏
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Elamipretide effects on the skeletal muscle phosphoproteome in aged female mice Campbell, Matthew D.; Martin-Perez, Miguel; Egertson, Jarrett D.; Gaffrey, Matthew J.; Wang, Lu; Bammler, Theo; Rabinovitch, Peter S.; MacCoss, Michael; Qian, Wei-Jun; Villen, Judit; Marcinek, David 分享 收藏
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice Strong, Randy; Miller, Richard A.; Cheng, Catherine J.; Nelson, James F.; Gelfond, Jonathan; Allani, Shailaja Kesaraju; Diaz, Vivian; Dorigatti, Angela Olsen; Dorigatti, Jonathan; Fernandez, Elizabeth; Galecki, Andrzej; Ginsburg, Brett; Hamilton, Karyn L.; Javors, Martin A.; Kornfeld, Kerry; Kaeberlein, Matt; Kumar, Suja; Lombard, David B.; Lopez-Cruzan, Marisa; Miller, Benjamin F.; Rabinovitch, Peter; Reifsnyder, Peter; Rosenthal, Nadia A.; Bogue, Molly A.; Salmon, Adam B.; Suh, Yousin; Verdin, Eric; Weissbach, Herbert; Newman, John; Maccchiarini, Francesca; Harrison, David E. 分享 收藏
TurnoveR: A Skyline External Tool for Analysis of Protein Turnover in Metabolic Labeling Studies Basisty, Nathan; Shulman, Nicholas; Wehrfritz, Cameron; Marsh, Alexandra N.; Shah, Samah; Rose, Jacob; Ebert, Scott; Miller, Matthew; Dai, Dao-Fu; Rabinovitch, Peter S.; Adams, Christopher M.; MacCoss, Michael J.; MacLean, Brendan; Schilling, Birgit 分享 收藏
Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment Whitson, Jeremy A.; Johnson, Richard; Wang, Lu; Bammler, Theo K.; Imai, Shin-Ichiro; Zhang, Huiliang; Fredrickson, Jeanne; Latorre-Esteves, Elena; Bitto, Alessandro; MacCoss, Michael J.; Rabinovitch, Peter S. 分享 收藏
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice 衰老小鼠视网膜和视网膜色素上皮细胞代谢变化的分析 Tsantilas, Kristine A.; Cleghorn, Whitney M.; Bisbach, Celia M.; Whitson, Jeremy A.; Hass, Daniel T.; Robbings, Brian M.; Sadilek, Martin; Linton, Jonathan D.; Rountree, Austin M.; Valencia, Ana P.; Sweetwyne, Mariya T.; Campbell, Matthew D.; Zhang, Huiliang; Jankowski, Connor S. R.; Sweet, Ian R.; Marcinek, David J.; Rabinovitch, Peter S.; Hurley, James B. 分享 收藏
A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA Sanchez-Contreras, Monica; Sweetwyne, Mariya T.; Kohrn, Brendan F.; Tsantilas, Kristine A.; Hipp, Michael J.; Schmidt, Elizabeth K.; Fredrickson, Jeanne; Whitson, Jeremy A.; Campbell, Matthew D.; Rabinovitch, Peter S.; Marcinek, David J.; Kennedy, Scott R. 分享 收藏
Persistent or recurrent Barrett's neoplasia after an endoscopic therapy session is associated with DNA content abnormality and can be detected by DNA flow cytometric analysis of paraffin-embedded tissue Bowman, Christopher J.; Zhang, Ruth; Balitzer, Dana; Wang, Dongliang; Rabinovitch, Peter S.; Kovari, Bence P.; Mattis, Aras N.; Kakar, Sanjay; Lauwers, Gregory Y.; Choi, Won-Tak 分享 收藏
Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins Elamipretide (SS-31) 治疗可减弱与年龄相关的心脏蛋白翻译后修饰 Whitson, Jeremy A.; Martin-Perez, Miguel; Zhang, Tong; Gaffrey, Matthew J.; Merrihew, Gennifer E.; Huang, Eric; White, Collin C.; Kavanagh, Terrance J.; Qian, Wei-Jun; Campbell, Matthew D.; MacCoss, Michael J.; Marcinek, David J.; Villen, Judit; Rabinovitch, Peter S. 分享 收藏
University of Washington Nathan Shock Center: innovation to advance aging research 华盛顿大学内森休克中心: 创新推进老龄化研究 Kaeberlein, Matt; Bitto, Alessandro; Dunham, Maitreya J.; Ladiges, Warren; Lee, Su-In; MacCoss, Michael J.; Mendenhall, Alexander; Promislow, Daniel E. L.; Rabinovitch, Peter S.; Villen, Judit; Wang, Lu; Wang, Yuliang; Young, Jessica E. 分享 收藏
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