未登录 The epigenetic impact and therapeutic opportunity of AR-directed therapy for desmoplastic small round cell tumor Truong, Danh D.; Lamhamedi-Cherradi, Salah-Eddine; Maitituoheti, Mayinuer; Beird, Hannah C.; Wu, Chia-Chin; Krishnan, Sandhya; Ingram, Davis; Futreal, P. Andrew; Titus, Mark; Lazar, Alexander; Rai, Kunal; MacLeod, A. Robert; Daw, Najat C.; Hayes, Andrea; Ludwig, Joseph 分享 收藏
The epigenetic impact and therapeutic opportunity of AR-directed therapy for DSRCT Truong, Danh; Lamhamedi-Cherradi, Salah-Eddine; Maitituoheti, Mayinuer; Beird, Hannah C.; Arslan, Emre; Wu, Chia-Chin; Krishnan, Sandhya; Ingram, Davis; Futreal, P. Andrew; Titus, Mark; Rai, Kunal; Lazar, Alexander; MacLeod, A. Robert; Ratan, Ravin; Livingston, John Andrew; Daw, Najat; Hayes-Dixon, Andrea; Ludwig, Joseph 分享 收藏
The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma Lamhamedi-Cherradi, Salah-Eddine; Maitituoheti, Mayinuer; Menegaz, Brian A.; Krishnan, Sandhya; Vetter, Amelia M.; Camacho, Pamela; Wu, Chia-Chin; Beird, Hannah C.; Porter, Robert W.; Ingram, Davis R.; Ramamoorthy, Vandhana; Mohiuddin, Sana; McCall, David; Truong, Danh D.; Cuglievan, Branko; Futreal, P. Andrew; Velasco, Alejandra Ruiz; Anvar, Nazanin Esmaeili; Utama, Budi; Titus, Mark; Lazar, Alexander J.; Wang, Wei-Lien; Rodriguez-Aguayo, Cristian; Ratan, Ravin; Livingston, John A.; Rai, Kunal; MacLeod, A. Robert; Daw, Najat C.; Hayes-Jordan, Andrea; Ludwig, Joseph A. 分享 收藏
Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target (vol 74, pg 1155, 2021) Ningarhari, Massih; Caruso, Stefano; Hirsch, Theo Z.; Bayard, Quentin; Franconi, Andrea; Vedie, Anne-Laure; Noblet, Benedicte; Blanc, Jean-Frederic; Amaddeo, Giuliana; Ganne, Nathalie; Ziol, Marianne; Paradis, Valerie; Guettier, Catherine; Calderaro, Julien; Morcrette, Guillaume; Kim, Youngsoo; MacLeod, A. Robert; Nault, Jean-Charles; Rebouissou, Sandra; Zucman-Rossi, Jessica 分享 收藏
Inhibition of Prekallikrein for Hereditary Angioedema Fijen, Laure M.; Riedl, Marc A.; Bordone, Laura; Bernstein, Jonathan A.; Raasch, Jason; Tachdjian, Raffi; Craig, Timothy; Lumry, William R.; Manning, Michael E.; Alexander, Veronica J.; Newman, Kenneth B.; Revenko, Alexey; Baker, Brenda F.; Nanavati, Charvi; MacLeod, A. Robert; Schneider, Eugene; Cohn, Danny M. 分享 收藏
Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling Kapustin, Alexander N.; Davey, Paul; Longmire, David; Matthews, Carl; Linnane, Emily; Rustogi, Nitin; Stavrou, Maria; Devine, Paul W. A.; Bond, Nicholas J.; Hanson, Lyndsey; Sonzini, Silvia; Revenko, Alexey; MacLeod, A. Robert; Ross, Sarah; Chiarparin, Elisabetta; Puri, Sanyogitta 分享 收藏
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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption Mondala, Phoebe K.; Vora, Ashni A.; Zhou, Tianyuan; Lazzari, Elisa; Ladel, Luisa; Luo, Xiaolin; Kim, Youngsoo; Costello, Caitlin; MacLeod, A. Robert; Jamieson, Catriona H. M.; Crews, Leslie A. 分享 收藏
LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma (vol 18, 141, 2019) Xu, Yan; Li, Yuan; Jin, Jiankang; Han, Guangchun; Sun, Chengcao; Pizzi, Melissa Pool; Huo, Longfei; Scott, Ailing; Wang, Ying; Ma, Lang; Lee, Jeffrey H.; Bhutani, Manoop S.; Weston, Brian; Vellano, Christopher; Yang, Liuqing; Lin, Chunru; Kim, Youngsoo; MacLeod, A. Robert; Wang, Linghua; Wang, Zhenning; Song, Shumei; Ajani, Jaffer A. 分享 收藏
Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis Koehlera, Juliane; Maletzki, Claudia; Koczan, Dirk; Frank, Marcus; Springer, Armin; Steffen, Carolin; Revenko, Alexey S.; MacLeod, A. Robert; Mikkat, Stefan; Kreikemeyer, Bernd; Oehmcke-Hecht, Sonja 分享 收藏
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LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma LncRNA PVT1上调是不良的预后指标，可作为食管腺癌的治疗靶点 Xu, Yan; Li, Yuan; Jin, Jiankang; Han, Guangchun; Sun, Chengcao; Pizzi, Melissa Pool; Huo, Longfei; Scott, Ailing; Wang, Ying; Ma, Lang; Lee, Jeffrey H.; Bhutani, Manoop S.; Weston, Brian; Vellano, Christopher; Yang, Liuqing; Lin, Chunru; Kim, Youngsoo; MacLeod, A. Robert; Wang, Linghua; Wang, Zhenning; Song, Shumei; Ajani, Jaffer A. 分享 收藏
Targeting castration-resistant prostate cancer with androgen receptor antisense oligonucleotide therapy De Velasco, Marco A.; Kura, Yurie; Sakai, Kazuko; Hatanaka, Yuji; Davies, Barry R.; Campbell, Hayley; Klein, Stephanie; Kim, Youngsoo; MacLeod, A. Robert; Sugimoto, Koichi; Yoshikawa, Kazuhiro; Nishio, Kazuto; Uemura, Hirotsugu 分享 收藏
Enhanced Potency of GalNAc-Conjugated Antisense Oligonucleotides in Hepatocellular Cancer Models Kim, Youngsoo; Jo, Minji; Schmidt, Joanna; Luo, Xiaolin; Prakash, Thazha P.; Zhou, Tianyuan; Klein, Stephanie; Xiao, Xiaokun; Post, Noah; Yin, Zhengfeng; MacLeod, A. Robert 分享 收藏
The contact system proteases play disparate roles in streptococcal sepsis Koehler, Juliane; Maletzki, Claudia; Koczan, Dirk; Frank, Marcus; Trepesch, Carolin; Revenko, Alexey S.; Crosby, Jeffrey R.; Macleod, A. Robert; Mikkat, Stefan; Oehmcke-Hecht, Sonja 分享 收藏
Discovery and characterization of AZD8701, a high affinity antisense oligonucleotide targeting FOXP3 to relieve immunosuppression in cancer Sinclair, Charles; Revenko, Alexey S.; Johnson, R. B.; Peter, Alison; Taylor, Molly A.; Hettrick, Lisa A.; Klein, Stephanie; Solanki, Anisha; Chapman, Melissa; Yates, James; Angell, Helen K.; Watt, Andrew; Gattis, Danielle; Monia, Brett P.; Barry, Simon T.; Lyne, Paul; Edbrooke, Mark; Goldberg, Frederick; Macleod, A. R. 分享 收藏
An HK2 Antisense Oligonucleotide Induces Synthetic Lethality in HK1-HK2+ Multiple Myeloma Xu, Shili; Zhou, Tianyuan; Doh, Hanna M.; Trinh, K. Ryan; Catapang, Art; Lee, Jason T.; Braas, Daniel; Bayley, Nicholas A.; Yamada, Reiko E.; Vasuthasawat, Alex; Sasine, Joshua P.; Timmerman, John M.; Larson, Sarah M.; Kim, Youngsoo; MacLeod, A. Robert; Morrison, Sherie L.; Herschman, Harvey R. 分享 收藏
IONIS-PKKRx a Novel Antisense Inhibitor of Prekallikrein and Bradykinin Production Ferrone, Jason D.; Bhattacharjee, Gourab; Revenko, Alexey S.; Zanardi, Thomas A.; Warren, Marshelle S.; Derosier, Frederick J.; Viney, Nicholas J.; Pham, Nguyen C.; Kaeser, Gwendolyn E.; Baker, Brenda F.; Schneider, Eugene; Hughes, Steven G.; Monia, Brett P.; MacLeod, A. Robert 分享 收藏
Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines Linnane, Emily; Davey, Paul; Zhang, Pei; Puri, Sanyogitta; Edbrooke, Mark; Chiarparin, Elisabetta; Revenko, Alexey S.; Macleod, A. Robert; Norman, Jim C.; Ross, Sarah J. 分享 收藏
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