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Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples 同源重组缺陷标志物（HRDsig）在泛肿瘤组织样本中的分析验证 Li, Wenshu; Leibowitz, Jeffrey A.; Wang, Shuoguo; Walker, Louisa; Xu, Chang; Chen, Kuei-Ting; Schrock, Alexa B.; Hughes, Jason; Patel, Nimesh; Elvin, Julia A.; Ritterhouse, Lauren L.; Sokol, Ethan; Frampton, Garrett; Dennis, Lucas; Yilmazel, Bahar; Decker, Brennan 分享 收藏
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LODESTAR: A Single Arm Phase II Study of Rucaparib in Solid Tumors with Pathogenic Germline or Somatic Variants in Homologous Recombination Repair (HRR) Genes Anbil, Sriram; Seewald, Nicholas J.; Lin, Kevin; Craib, Marcia; Connor, Christy; Giordano, Heidi; McLachlan, Karen; Kwan, Tanya; Maloney, Lara; Tukachinsky, Hanna; Schrock, Alexa; Wang, Shuoguo; Sokol, Ethan; Decker, Brennan; Nathanson, Katherine; Domchek, Susan; Reiss, Kim 分享 收藏
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Ancestry-associated co-alteration landscape of KRAS and EGFR-altered non-squamous NSCLC Sisoudiya, Saumya D.; Houle, Armande Ang; Fernando, Tharu; Wilson, Timothy R.; Schutzman, Jennifer L.; Lee, Jessica; Schrock, Alexa; Sokol, Ethan S.; Sivakumar, Smruthy; Shi, Zhen; Pathria, Gaurav 分享 收藏
Immune checkpoint inhibitors for POLE or POLD1 proofreading-deficient metastatic colorectal cancer Ambrosini, M.; Rousseau, B.; Manca, P.; Artz, O.; Marabelle, A.; Andre, T.; Maddalena, G.; Mazzoli, G.; Intini, R.; Cohen, R.; Cercek, A.; Segal, N. H.; Saltz, L.; Varghese, A. M.; Yaeger, R.; Nusrat, M.; Goldberg, Z.; Ku, G. Y.; El Dika, I.; Margalit, O.; Grinshpun, A.; Kasi, P. Murtaza; Schilsky, R.; Lutfi, A.; Shacham-Shmueli, E.; Afghan, M. Khan; Weiss, L.; Westphalen, C. B.; Conca, V.; Decker, B.; Randon, G.; Elez, E.; Fakih, M.; Schrock, A. B.; Cremolini, C.; Jayachandran, P.; Overman, M. J.; Lonardi, S.; Pietrantonio, F. 分享 收藏
ESR1 genomic alterations (GAs) and coexistent putative resistance alterations in comprehensive genomic profiling (CGP) of metastatic breast cancer (MBC) McArthur, Heather; Tukachinsky, Hanna; Schrock, Alexa; Madison, Russell; Holmes, Oliver; Sivakumar, Smruthy; Sokol, Ethan; Graf, Ryon; Quintanilha, Julia; Dougherty, Kali; Pasquina, Lincoln; Oxnard, Geoffrey; Levy, Mia; Winer, Eric 分享 收藏
ESR1 mutations (ESR1mut) in HR(+)HER2(-)patients with metastatic breast cancer (MBC): prevalence along treatment course and predictive value for endocrine therapy (ET) resistance in real-world practice Bhave, Manali; Quintanilha, Julia; Graf, Ryon; Scott, Takara; Tukachinsky, Hanna; Li, Gerald; Schrock, Alexa; Oxnard, Geoffrey; Levy, Mia; Kalinsky, Kevin 分享 收藏
Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors Pecci, Federica; Nakazawa, Seshiru; Ricciuti, Biagio; Harada, Guilherme; Lee, Jessica K.; Alessi, Joao V.; Barrichello, Adriana; Vaz, Victor R.; Lamberti, Giuseppe; Di Federico, Alessandro; Gandhi, Malini M.; Gazgalis, Dimitris; Feng, William W.; Jiang, Jie; Baldacci, Simon; Locquet, Marie-Anais; Gottlieb, Felix H.; Chen, Monica F.; Lee, Elinton; Haradon, Danielle; Smokovich, Anna; Voligny, Emma; Nguyen, Tom; Goel, Vikas K.; Zimmerman, Zachary; Atwal, Sumandeep; Wang, Xinan; Bahcall, Magda; Heist, Rebecca S.; Iqbal, Sumaiya; Gandhi, Nishant; Elliott, Andrew; Vanderwalde, Ari M.; Ma, Patrick C.; Halmos, Balazs; Liu, Stephen V.; Che, Jianwei; Schrock, Alexa B.; Drilon, Alexander; Janne, Pasi A.; Awad, Mark M. 分享 收藏
Genomic profiling of KRAS and EGFR-altered non-squamous non-small cell lung cancer reveal ancestry-specific co-alterations with therapeutic implications Sisoudiya, Saumya D.; Houle, Armande A.; Fernando, Tharu M.; Wilson, Timothy R.; Schutzman, Jennifer L.; Lee, Jessica K.; Schrock, Alexa B.; Sokol, Ethan S.; Sivakumar, Smruthy; Shi, Zhen; Pathria, Gaurav 分享 收藏
Liquid biopsy-based circulating tumour (ct)DNA analysis of a spectrum of myeloid and lymphoid malignancies yields clinically actionable results Mata, Douglas A.; Lee, Jessica K.; Shanmugam, Vignesh; Marcus, Chelsea B.; Schrock, Alexa B.; Williams, Erik A.; Ritterhouse, Lauren L.; Hickman, Richard A.; Janovitz, Tyler; Patel, Nimesh R.; Kroger, Benjamin R.; Ross, Jeffrey S.; Mirza, Kamran M.; Oxnard, Geoffrey R.; Vergilio, Jo-Anne; Elvin, Julia A.; Benhamida, Jamal K.; Decker, Brennan; Xu, Mina L. 分享 收藏
Comprehensive genomic profiling and treatment patterns across ancestries in advanced prostate cancer: a large-scale retrospective analysis Sivakumar, Smruthy; Lee, Jessica K.; Moore, Jay A.; Hopkins, Julia; Newberg, Justin Y.; Madison, Russell; Graf, Ryon; Schrock, Alexa B.; Kobetz, Erin; Vince, Randy; Franco, Idalid; Seldon, Crystal; Frampton, Garrett M.; Mills, Jennifer; Venstrom, Jeffrey; Mahal, Brandon A. 分享 收藏
POLE-specific variant classification strategy is critical for identifying patients who may benefit from immunotherapy Keller, Rachel B.; Haberberger, James; Janovitz, Tyler; Schrock, Alexa B.; Tukachinsky, Hanna; Zhong, Lei; Mata, Douglas A.; Lopez, Lyle V.; Fleischmann, Zoe; Sharaf, Radwa; Sokol, Ethan S.; Frampton, Garrett M.; Patel, Nimesh R.; Lin, Douglas I.; Oxnard, Geoff R.; Williams, Erik A.; Elvin, Julia A.; Decker, Brennan 分享 收藏
Genomic landscape of 891 RET fusions detected across diverse solid tumor types Parimi, Vamsi; Tolba, Khaled; Danziger, Natalie; Kuang, Zheng; Sun, Daokun; Lin, Douglas I.; Hiemenz, Matthew C.; Schrock, Alexa B.; Ross, Jeffrey S.; Oxnard, Geoffrey R.; Huang, Richard S. P. 分享 收藏
Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis Huang, Richard S. P.; Carbone, David P.; Li, Gerald; Schrock, Alexa; Graf, Ryon P.; Zhang, Liangliang; Murugesan, Karthikeyan; Ross, Jeffrey S.; Tolba, Khaled; Sands, Jacob; Oxnard, Geoffrey R.; Spigel, David 分享 收藏
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Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors KRAS改变癌症的全面泛癌症基因组景观和实体瘤的现实世界结果 Lee, Jessica K.; Sivakumar, Smruthy; Schrock, Alexa B.; Madison, Russell; Fabrizio, David; Gjoerup, Ole; Ross, Jeffrey S.; Frampton, Garrett M.; Napalkov, Pavel; Montesion, Meagan; Schutzman, Jennifer L.; Ye, Xin; Hegde, Priti S.; Nagasaka, Misako; Oxnard, Geoffrey R.; Sokol, Ethan S.; Ou, Sai-Hong Ignatius; Shi, Zhen 分享 收藏
Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma Margolis, Matthew; Janovitz, Tyler; Laird, Jason; Mata, Douglas A.; Montesion, Meagan; Lee, Jessica K.; Madison, Russell W.; Schrock, Alexa B.; Tukachinsky, Hanna; Allen, Justin M.; Erlich, Rachel; Hiemenz, Matthew C.; Huang, Richard S. P.; Elvin, Julia; Vergilio, Jo-Anne; Lin, Douglas, I; Ross, Jeffrey; Oxnard, Geoffrey; Decker, Brennan 分享 收藏
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